EKS-POA-00139

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00139

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	286.2	1.8E-85	96	318	223

Status

Unreviewed

Ensembl Protein

ENSPPYP00000017504

UniProt Accession

H2PG62;

Protein Name

Protein Synonyms/Alias

Gene Name

RIOK2

Gene Synonyms/Alias

RIOK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000015654	ENSPPYP00000017504	ENSPPYT00000018212

Organism

Pongo abelii

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MGKVNVAKLR YMSRDDFRVL TAVEMGMKNH EIVPGSLIAS IASLKHGGCN KVLRELVKHK 60

LIAWERTKTV QGYRLTNAGY DYLALKTLSS RQVVESVGNQ MGVGKESDIY IVANEEGQQF 120

ALKLHRLGRT SFRNLKNKRD YHKHRHNVSW LYLSRLSAMK EFAYMKALYE RKFPVPKPID 180

YNRHAVVMEL INGYPLCQIH HVEDPASVYD EAMELIVRLA NHGLIHGDFN EFNLILDEND 240

HITMIDFPQM VSTSHPNAEW YFDRDVKCIK DFFMKRFSYE SELFPAFKDI KREDTLDVEV 300

SASGYTKEMQ ADDELLHPLG PDDKNIETKE GSEFSFSDGE VAEKAEVYRS ENESERNCLE 360

ESEGCYCRSS GDPEQIKEDS LSEESADARS FEMTEFNQAL EEIKGQVVEK NSVTEFSEEK 420

NRTENYNRQD GQRVQVGVPA GSDEYEDECP HLIALSSLNR EFRPFRDEEN MGAMNQYRTR 480

TLSITSSGSV VSCSTIPPEL VKQKVKRQLT KQQKSAVRRR LQKGEANIFT KQRRENMQNI 540

KSSLEAASFW GE 552

Nucleotide Sequence
(FASTA)

ATGGGGAAGG TGAATGTGGC TAAGTTGCGT TACATGAGCC GAGATGACTT CAGGGTCTTG 60

ACCGCAGTTG AAATGGGCAT GAAGAACCAT GAAATTGTTC CCGGCAGTTT GATTGCTTCT 120

ATAGCCAGCC TTAAACATGG TGGCTGTAAT AAAGTTTTAA GAGAATTAGT GAAACATAAA 180

CTCATAGCTT GGGAGCGTAC CAAAACTGTC CAGGGCTATC GGTTGACAAA TGCAGGATAT 240

GATTACCTAG CTTTGAAAAC ACTCTCTTCT AGGCAAGTAG TTGAGTCTGT TGGAAACCAG 300

ATGGGTGTTG GCAAAGAATC AGATATTTAC ATTGTTGCAA ATGAAGAAGG ACAACAATTT 360

GCATTAAAGC TTCACAGACT AGGAAGAACC TCGTTTCGAA ATCTGAAAAA CAAACGCGAT 420

TATCATAAAC ATAGGCACAA TGTGTCTTGG CTTTATTTAT CTCGTCTCTC TGCCATGAAG 480

GAATTTGCCT ATATGAAGGC ATTGTATGAG AGGAAATTTC CAGTTCCAAA GCCAATTGAT 540

TACAATCGTC ATGCAGTGGT CATGGAACTC ATAAATGGTT ATCCACTATG TCAGATACAC 600

CATGTTGAAG ATCCTGCATC AGTATACGAT GAAGCTATGG AACTAATTGT CAGACTTGCA 660

AATCATGGGC TGATTCATGG AGATTTTAAT GAATTTAATC TCATTTTGGA TGAAAATGAC 720

CATATCACCA TGATTGATTT TCCACAGATG GTTTCAACTT CTCATCCCAA TGCTGAGTGG 780

TATTTTGACA GAGATGTTAA ATGCATTAAA GATTTCTTCA TGAAACGTTT CAGCTACGAA 840

AGTGAGCTTT TTCCAGCCTT TAAGGATATC AAGAGGGAAG ATACTCTTGA TGTGGAGGTT 900

TCTGCCAGTG GCTACACAAA GGAAATGCAG GCAGATGATG AACTGCTTCA TCCATTAGGT 960

CCAGATGATA AAAATATTGA AACAAAAGAG GGATCTGAAT TCTCATTTTC AGATGGAGAA 1020

GTGGCAGAAA AAGCAGAGGT TTACAGGTCA GAAAATGAAA GTGAGCGGAA CTGTCTAGAA 1080

GAATCAGAGG GCTGCTATTG CAGATCATCT GGAGACCCTG AACAAATAAA GGAAGACAGT 1140

TTATCAGAAG AGAGTGCTGA TGCACGGAGT TTTGAAATGA CTGAATTCAA TCAAGCTTTA 1200

GAAGAAATAA AAGGGCAGGT TGTTGAAAAG AACTCTGTAA CTGAATTTTC TGAGGAGAAA 1260

AACAGAACTG AAAATTACAA CAGGCAAGAT GGTCAGAGAG TTCAAGTAGG AGTCCCTGCT 1320

GGCTCTGACG AGTATGAAGA TGAGTGCCCT CATCTAATTG CCTTGTCGTC ATTAAATAGA 1380

GAATTCAGGC CTTTCAGAGA TGAAGAAAAT ATGGGAGCTA TGAATCAGTA TAGAACAAGA 1440

ACTCTGAGTA TCACTTCTTC AGGCAGTGTT GTAAGCTGTT CAACAATTCC TCCAGAACTG 1500

GTGAAACAGA AGGTGAAACG TCAGTTGACA AAACAGCAAA AATCAGCTGT CAGACGTCGA 1560

TTACAGAAAG GAGAAGCAAA TATATTTACC AAGCAACGTC GGGAAAACAT GCAAAATATC 1620

AAATCAAGTT TGGAAGCAGC TAGCTTTTGG GGAGAATAA 1659

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiy...ktsllvlknrdkYvdgefrfkksrska  58

         svgn++gvgkesd+y v++++g+++a+K++   +ts+++lkn+++Y       +k+r+++

Q: 96    SVGNQMGVGKESDIYIVANEEGQQFALKLHrlgRTSFRNLKNKRDY-------HKHRHNV  148

         79********************************************.......9******

S: 59    nprklsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklke  118

         ++++lsrl+A+KEf+++k+lye+++pvP+pid++rh++vmeli  +gyp+++++    +

Q: 149   SWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NGYPLCQIH----HV  202

         *******************************************..*********....9*

S: 119   eeikelYsdllalivklynegrLvHaDlsEfnill.eddklvliDvsqsveieHpdalef  177

         e+ +++Y+++++liv+l+n+g L+H+D++Efn++l e+d++++iD++q+v+++Hp+a+++

Q: 203   EDPASVYDEAMELIVRLANHG-LIHGDFNEFNLILdENDHITMIDFPQMVSTSHPNAEWY  261

         *********************.*************889**********************

S: 178   lrrDvknvkefFkkklvy.........dvlrerelfelvsasgltkekeaddeilea  225

         ++rDvk++k+fF+k+++y         d++re++l+ +vsasg+tke++adde+l++

Q: 262   FDRDVKCIKDFFMKRFSYeselfpafkDIKREDTLDVEVSASGYTKEMQADDELLHP  318

         *****************************************************9987

Domain Sequence
(FASTA)

SVGNQMGVGK ESDIYIVANE EGQQFALKLH RLGRTSFRNL KNKRDYHKHR HNVSWLYLSR 60

LSAMKEFAYM KALYERKFPV PKPIDYNRHA VVMELINGYP LCQIHHVEDP ASVYDEAMEL 120

IVRLANHGLI HGDFNEFNLI LDENDHITMI DFPQMVSTSH PNAEWYFDRD VKCIKDFFMK 180

RFSYESELFP AFKDIKREDT LDVEVSASGY TKEMQADDEL LHP 223

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

pon:100438719

;

InterPros

IPR011009	; Kinase-like_dom.
IPR018934	; RIO-like_kinase.
IPR015285	; RIO2_kinase_winged_hlx_N.
IPR018935	; RIO_kinase_CS.
IPR011991	; WHTH_trsnscrt_rep_DNA-bd.

Pfam

PF01163	; RIO1; 1.
PF09202	; Rio2_N; 1.

SMARTs

Prosites

PS01245

; RIO1; 1.

Prints

Created Date

20-Feb-2013