EKS-POA-00164

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00164

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	493.8	1.3E-148	524	790	267

Status

Unreviewed

Ensembl Protein

ENSPPYP00000018801

UniProt Accession

H2PJN3;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000016795	ENSPPYP00000018801	ENSPPYT00000019543

Organism

Pongo abelii

Functional Description

Protein Length

855

Protein Sequence
(FASTA)

MESEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK ISADTTDNSG TVNQIMMMAN 60

NPEDWLSLLL KLEKNSVPLS DALLNKLIGR YSQAIEALPP DKYGQNESFA RIQVRFAELK 120

AIQEPDDARD YFQMARANCK KFAFVHISFA QFELSQGNVK KSKQLLQKAV ERGAVPLEML 180

EIALRNLNLQ KKQLLSEEEK KNLSASTVLT AQESFSSSLG HLQNRNNSCD SRGQTTKARF 240

LYGENMPPQD AEIGYRNSLR QTNKTKSSCP FGRVPVNLLS SPDCDVKTDD SVVPCFIKRQ 300

TSRSECRDLV PGSKPSGNDS CELRNLKSVQ NSHFKEPLVS DEKSSELIIT DSITLKNKTE 360

SSLLAKLEET KEYQEPEVPE SNQKQWQSKR KSECINQNPA ASSNHWQIPE LARKVNTEQK 420

HTTFEQPVFS VSKQSPPISA SKWFDPKSIC KTPSSNTLDD YMSCFRTPVV KNDFPPACQL 480

STPYGQPACF QQQQQQILAT PLQNLQVLAS SSANECISVK GRIYSILKQI GSGGSSKVFQ 540

VLNEKKQIYA IKYVNLEEAD NQTLDSYRNE IAYLNKLQQH SDKIIRLYDY EITDQYIYMV 600

MECGNIDLNS WLKKKKSIDP WERKSYWKNM LEAVHTIHQH GIVHSDLKPA NFLIVDGMLK 660

LIDFGIANQM QPDTTSIVKD SQVGTVNYMP PEAIKDMSSS RENGKSKSKI SPKSDVWSLG 720

CILYYMTYGK TPFQQIINQI SKLHAIIDPN HEIEFPDIPE KDLQDVLKCC LKRDPKQRIS 780

IPELLAHPYV QIQTHPGNQM AKGTTEEMKY VLGQLVGLNS PNSILKAAKT LYEHYSGGES 840

HNSSSKTFEK KREKK 855

Nucleotide Sequence
(FASTA)

ATGGAGTCCG AGGATTTAAG TGGCAGAGAA TTGACAATTG ATTCCATAAT GAACAAAGTG 60

AGAGACATTA AAAATAAGTT TAAAAATGAA GACCTTACTG ATGAACTAAG CTTGAATAAA 120

ATTTCTGCTG ATACTACAGA TAACTCGGGA ACTGTTAACC AAATTATGAT GATGGCAAAC 180

AACCCAGAGG ACTGGTTGAG TTTGTTGCTC AAACTGGAGA AAAACAGTGT TCCGCTAAGT 240

GATGCTCTTT TAAATAAATT GATTGGTCGT TACAGTCAAG CAATTGAAGC GCTTCCCCCA 300

GATAAATATG GCCAAAATGA GAGTTTTGCT AGAATTCAAG TGAGATTTGC TGAATTAAAA 360

GCTATTCAAG AGCCAGATGA TGCACGTGAC TACTTTCAAA TGGCCAGAGC AAACTGCAAG 420

AAATTTGCTT TTGTTCATAT CTCTTTTGCA CAATTTGAAC TGTCACAAGG TAATGTCAAA 480

AAAAGTAAAC AACTTCTTCA AAAAGCTGTA GAACGTGGAG CAGTACCACT AGAAATGCTG 540

GAAATTGCCC TACGGAATTT AAACCTCCAA AAAAAGCAGC TGCTTTCAGA GGAGGAAAAG 600

AAGAATTTAT CAGCATCTAC GGTATTAACT GCCCAAGAAT CATTTTCCAG TTCACTTGGG 660

CATTTACAGA ATAGGAACAA CAGTTGTGAT TCCAGAGGAC AGACTACTAA AGCCAGGTTT 720

TTATATGGAG AGAACATGCC ACCACAAGAT GCAGAAATAG GTTATCGGAA TTCATTGAGA 780

CAAACTAACA AAACTAAATC ATCATGCCCA TTTGGAAGAG TCCCAGTTAA CCTTCTAAGT 840

AGCCCAGATT GTGATGTGAA GACAGATGAT TCAGTTGTAC CTTGTTTTAT AAAAAGACAA 900

ACCTCTAGAT CAGAATGCCG AGATTTGGTG CCCGGATCTA AACCAAGTGG AAATGATTCC 960

TGTGAATTGA GAAATTTAAA GTCCGTTCAG AATAGCCATT TCAAGGAACC TCTGGTGTCA 1020

GATGAAAAGA GTTCTGAACT TATTATTACT GATTCAATAA CCCTGAAGAA TAAAACTGAA 1080

TCAAGTCTTC TAGCTAAATT AGAAGAAACT AAAGAGTATC AAGAACCAGA GGTTCCAGAG 1140

AGTAACCAGA AACAGTGGCA ATCTAAGAGA AAGTCAGAGT GTATTAACCA GAATCCTGCT 1200

GCATCTTCAA ATCACTGGCA GATTCCAGAG TTAGCCCGAA AAGTTAATAC AGAGCAGAAA 1260

CATACCACTT TTGAGCAACC TGTCTTTTCA GTTTCAAAAC AGTCACCACC AATATCAGCA 1320

TCTAAATGGT TTGACCCAAA ATCTATTTGT AAGACACCAA GCAGCAATAC CTTGGATGAT 1380

TACATGAGCT GTTTTAGAAC TCCAGTTGTA AAGAATGACT TTCCACCTGC TTGTCAGTTG 1440

TCAACACCTT ATGGCCAACC TGCCTGTTTC CAGCAGCAAC AGCAGCAAAT ACTTGCTACT 1500

CCACTTCAAA ATTTACAGGT TTTAGCATCC TCTTCAGCAA ATGAATGCAT TTCGGTTAAA 1560

GGAAGAATTT ATTCCATATT AAAGCAGATA GGAAGTGGAG GTTCAAGCAA GGTATTTCAG 1620

GTGTTGAATG AAAAGAAACA GATATATGCT ATAAAATATG TGAACTTAGA AGAAGCAGAT 1680

AACCAAACTC TTGATAGTTA CCGGAACGAA ATAGCTTATT TGAATAAACT ACAGCAACAC 1740

AGTGATAAGA TCATCCGACT TTATGATTAT GAAATCACGG ACCAGTACAT CTACATGGTA 1800

ATGGAGTGTG GAAATATTGA TCTTAATAGT TGGCTTAAAA AGAAAAAATC CATTGATCCA 1860

TGGGAACGCA AGAGTTACTG GAAAAATATG TTAGAGGCGG TTCACACAAT CCATCAACAT 1920

GGCATTGTTC ACAGTGATCT TAAACCAGCT AACTTTCTGA TAGTTGATGG AATGCTAAAG 1980

CTAATTGATT TTGGGATTGC AAACCAAATG CAACCAGATA CAACAAGTAT TGTTAAAGAT 2040

TCTCAGGTTG GCACAGTTAA TTATATGCCA CCAGAAGCAA TCAAAGATAT GTCTTCCTCC 2100

AGAGAGAATG GGAAATCTAA ATCAAAGATA AGCCCCAAAA GTGATGTTTG GTCCTTAGGA 2160

TGTATTTTGT ACTATATGAC TTACGGGAAA ACACCATTTC AGCAGATAAT TAATCAGATT 2220

TCTAAATTGC ATGCCATAAT TGATCCTAAT CATGAAATTG AATTTCCCGA TATTCCAGAG 2280

AAAGATCTTC AAGATGTGTT AAAGTGTTGT TTAAAAAGGG ACCCAAAACA GAGGATATCC 2340

ATTCCTGAGC TCCTGGCTCA TCCATATGTT CAAATTCAAA CTCATCCAGG TAACCAAATG 2400

GCCAAGGGAA CCACTGAAGA AATGAAATAT GTTCTGGGCC AACTTGTTGG TCTGAATTCT 2460

CCTAACTCCA TTTTGAAAGC TGCTAAAACT TTATATGAAC ACTATAGTGG TGGTGAAAGT 2520

CATAATTCAT CATCCAAGAC TTTTGAAAAA AAAAGGGAAA AAAAA 2565

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y+ilk++GsGGsskvf+v++ekk++ya+k+v+le+ad+qt+d+y+nei++l+klq++s k

Q: 524   YSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSdK  583

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++d+++y+vmecG+idln++lkkkksi+p +e++sy+k+mleav++ihqhGi

Q: 584   IIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDP-WERKSYWKNMLEAVHTIHQHGI  642

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfl+vdG+lklidfGian++++dttsivk+sqvGtvny++Pea+kdmsss

Q: 643   VHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMPPEAIKDMSSS--  700

         **********************************************************..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

           re++ksk+k+s+ksdvwslGcily+++ygktPf++i+nq+skl+aii+P++eiefP+i

Q: 701   --RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDI  758

         ..**********************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk+clkr+Pk+ris++ell++p+v

Q: 759   P---EKDLQDVLKCCLKRDPKQRISIPELLAHPYV  790

         *...*****************************96

Domain Sequence
(FASTA)

YSILKQIGSG GSSKVFQVLN EKKQIYAIKY VNLEEADNQT LDSYRNEIAY LNKLQQHSDK 60

IIRLYDYEIT DQYIYMVMEC GNIDLNSWLK KKKSIDPWER KSYWKNMLEA VHTIHQHGIV 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSIVKDSQV GTVNYMPPEA IKDMSSSREN 180

GKSKSKISPK SDVWSLGCIL YYMTYGKTPF QQIINQISKL HAIIDPNHEI EFPDIPEKDL 240

QDVLKCCLKR DPKQRISIPE LLAHPYV 267

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR011990	; TPR-like_helical.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013