EKS-POA-00456

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00456

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	338.7	2.7E-101	14	308	295

Status

Unreviewed

Ensembl Protein

ENSPPYP00000021251

UniProt Accession

H2PRE1;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK15

Gene Synonyms/Alias

MAPK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000018946	ENSPPYP00000021251	ENSPPYT00000022098
ENSPPYG00000018946	ENSPPYP00000021252	ENSPPYT00000022099

Organism

Pongo abelii

Functional Description

Protein Length

546

Protein Sequence
(FASTA)

MCTAVDPRIV RRYLLRRQLG QGAYGIVWKA VDRRTGEVVA IKKIFDAFRD KTDAQRTFRE 60

ITLLQEFGDH PNFIGLLDVI RAENDRDISP PPPTGVTLSA DTDLNAVIRK GGLLQDIHVR 120

SIFYQLLRAT RFLHSGHVVH RDQKPSNVLL DANCTVKLCD FGLARSLGDL PEGPEDQALT 180

EYVTRWYRAP EVLLSSHRYT LGVDMWSLGC ILGEMLRGRP LFPGTSTLHQ LELILETIPP 240

PSEEDLLALG SGCRAPVLHH LGSRPRQTLD ALLPPDTSPE ALDLLRQLLV FAPDKRLSAT 300

QALQHPYVQR FHCPSDEWAR KADVRLRAHE GVQLAAPEYR SRVYQMILER GGSSGTSRKK 360

GPERVSRSQA HVHKPRADPQ LPSGTRVQGP RPRPQSSLGH DPPEHESPCA AKNIPRQNSA 420

PLLQTALLGN GERPGAKEAP LTLSLVKPSG RGAAPSLTSQ AAAQVANQVL IRGDWNRGGG 480

VRVASTQQVP PRLPPEARPG RRMFSTSALQ GAQGAARALL GGYSQAYGTV CHSALGHLPL 540

LEGHRV 546

Nucleotide Sequence
(FASTA)

ATGTGCACCG CAGTGGACCC TCGCATCGTC CGGAGATACC TACTCAGGCG GCAGCTCGGG 60

CAGGGGGCCT ATGGCATTGT GTGGAAGGCA GTGGACCGGA GGACTGGTGA GGTCGTGGCC 120

ATCAAGAAAA TCTTTGATGC TTTTAGGGAT AAGACAGATG CCCAGAGAAC ATTCCGGGAA 180

ATCACGCTCC TCCAGGAGTT TGGGGACCAT CCCAACTTTA TTGGCCTCCT TGACGTGATC 240

CGGGCAGAGA ACGACAGGGA CATTAGCCCC CCACCCCCGA CTGGAGTGAC CCTCTCCGCA 300

GACACTGACC TGAACGCAGT CATCCGGAAG GGCGGGCTGC TGCAGGACAT CCACGTGCGC 360

TCCATCTTCT ACCAGCTCCT GCGGGCCACC CGGTTCCTCC ACTCCGGGCA CGTTGTGCAC 420

CGGGACCAGA AGCCGTCCAA TGTGCTCCTG GATGCCAACT GCACAGTGAA GCTGTGTGAC 480

TTTGGCCTGG CCCGCTCCCT GGGCGACCTC CCCGAGGGGC CTGAGGACCA GGCCTTGACA 540

GAGTACGTGA CACGCTGGTA CCGAGCTCCG GAGGTGTTGC TCTCTTCGCA CCGATACACC 600

CTTGGGGTGG ACATGTGGAG TCTGGGCTGT ATCCTGGGGG AGATGCTGCG AGGGAGGCCC 660

CTGTTCCCGG GTACGTCCAC CCTCCACCAG CTGGAGCTGA TCCTGGAGAC CATCCCGCCA 720

CCATCCGAGG AGGACCTCCT GGCTCTCGGT TCAGGCTGCC GTGCCCCTGT GCTGCACCAC 780

CTGGGGTCCC GGCCACGACA GACGCTGGAT GCCCTCCTAC CGCCAGACAC CTCCCCAGAG 840

GCGTTGGACC TCCTTAGGCA ACTCCTGGTG TTCGCCCCGG ACAAGCGGTT AAGCGCGACC 900

CAGGCACTGC AGCACCCCTA CGTGCAGAGG TTCCACTGCC CCAGTGACGA GTGGGCACGA 960

AAGGCAGATG TGCGGCTCCG GGCACACGAA GGGGTCCAGC TCGCTGCACC TGAGTACCGC 1020

AGCCGCGTCT ATCAGATGAT CCTGGAGCGT GGAGGCAGCA GCGGCACCTC GAGAAAGAAG 1080

GGCCCGGAGC GTGTCTCCCG GAGCCAGGCA CACGTGCACA AACCCAGAGC CGACCCTCAG 1140

CTGCCTTCTG GGACACGTGT GCAGGGTCCC AGACCCAGGC CTCAGAGTAG CCTGGGCCAC 1200

GACCCCCCCG AGCACGAGTC CCCCTGTGCA GCCAAGAACA TTCCCAGGCA GAACTCCGCT 1260

CCCCTGCTCC AAACTGCACT CCTAGGGAAT GGGGAAAGGC CTGGGGCGAA GGAAGCGCCC 1320

TTGACACTCT CGCTGGTGAA GCCAAGCGGC AGGGGAGCTG CGCCCTCCCT GACCTCCCAG 1380

GCTGCGGCTC AGGTGGCCAA CCAGGTCCTG ATCCGGGGTG ACTGGAACCG GGGCGGTGGG 1440

GTGAGGGTGG CCAGCACACA ACAGGTCCCT CCCCGGCTTC CTCCGGAGGC CCGGCCCGGC 1500

CGGAGGATGT TCAGCACCTC TGCCTTGCAG GGTGCCCAGG GGGCTGCCAG GGCTTTGCTT 1560

GGAGGCTACT CCCAAGCCTA CGGGACTGTG TGCCACTCGG CACTGGGCCA CCTGCCCCTG 1620

CTGGAGGGGC ACCGTGTGTG A 1641

Domain Profile

S: 2     eslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkel.kheNi  60

           +++lg+Gayg+v++avd+rt+e vaikk++++f+++t+a+rt+RE++ll+e+ +h+N+

Q: 14    LLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFgDHPNF  73

         56799*******************************************************

S: 61    iklldvftpeeeleelk.dvYlvtelmetdLkkviksq.klsdehiklllyqilrglkyl  118

         i lldv+++e++ +        vt   +tdL++vi++   l+d h+++++yq+lr++++l

Q: 74    IGLLDVIRAENDRDISPpPPTGVTLSADTDLNAVIRKGgLLQDIHVRSIFYQLLRATRFL  133

         *********995554331345688899**********999********************

S: 119   HsanviHrDlKPsNllvnedcelkildFGlarsadkekekk....lteyvatrwYraPei  174

         Hs +v+HrD+KPsN+l++++c++k++dFGlars  +  e      lteyv trwYraPe+

Q: 134   HSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPedqaLTEYV-TRWYRAPEV  192

         *********************************766554444566***97.9********

S: 175   llslkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkiese  234

         lls+++yt  vD+Ws+GCIl+E+l+g+plfpg+++++qle+ile+++ psee+l ++ s

Q: 193   LLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSG  252

         ************************************************************

S: 235   earnyikslpkkkkkdfeelfpk.aseealdLleklLvldpdkRisveeaLehpYl  289

         + + ++++l +++++++++l+p  +s+ealdLl++lLv++pdkR+s+++aL+hpY+

Q: 253   CRAPVLHHLGSRPRQTLDALLPPdTSPEALDLLRQLLVFAPDKRLSATQALQHPYV  308

         ********************986599*****************************7

Domain Sequence
(FASTA)

LLRRQLGQGA YGIVWKAVDR RTGEVVAIKK IFDAFRDKTD AQRTFREITL LQEFGDHPNF 60

IGLLDVIRAE NDRDISPPPP TGVTLSADTD LNAVIRKGGL LQDIHVRSIF YQLLRATRFL 120

HSGHVVHRDQ KPSNVLLDAN CTVKLCDFGL ARSLGDLPEG PEDQALTEYV TRWYRAPEVL 180

LSSHRYTLGV DMWSLGCILG EMLRGRPLFP GTSTLHQLEL ILETIPPPSE EDLLALGSGC 240

RAPVLHHLGS RPRQTLDALL PPDTSPEALD LLRQLLVFAP DKRLSATQAL QHPYV 295

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013