EPS-PES-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PES-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	208.4	1.6E-61	642	887	246

Status

Unreviewed

Ensembl Protein

ENSPSIP00000003365

UniProt Accession

K7F5Q5;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000003216	ENSPSIP00000003365	ENSPSIT00000003381

Organism

Pelodiscus sinensis

Functional Description

Protein Length

1170

Protein Sequence
(FASTA)

SGKPHSTGNS ERIQLSGMYN VRKGKMHLPV NRWTRRQVIL CGTCLIVSSV KESQTGKMHV 60

LPLIGGKVEE VKKHQHCLAF SSSGPQSQTY YICFDTFTEY LRWLRQASKV ASQRISSVDL 120

SCCSLEHLPA NLFYSQDLTH LNLKQNFLRL NPSVSTTRGL SELQRFTKLK SLNLSNNNLG 180

DFPLAVCSIP TLTELNVSCN ALKSIPAAVG DMHNLQTLLL DGNFLHSLPN YLSLSFNEFT 240

DIPGVLEKLN GMDKLCMSGN CMETLSLQAL RRMPHIKHVD LRLNVIRRLV VDEVDFLHHV 300

TQLDLRDNKL CELDATIFNN IEVLHCERNH LVTLKISGYF LKALYAFSNE LVHLDVYPVP 360

NYLTSMDISR NHLESLPEWV CDSRKLEVLD VGHNQLCELP TRLFCSSSLR KLLSGHNQLG 420

RLPERFERTQ LEVLDVQHNQ LLELPSNLLL KADSLRSLNA SANKLETLPP ATLSEETNSI 480

LQELYLTNNN LTDKCVPLLT GHPHLKILHM AYNRLQSFPA SKMAKLEELE EIDISGNKLK 540

AIPTTIMNCR RMHTVIAHSN CIEVFPEVMQ LVEIKCVDLS CNELSEITLP ENLPPKLQEL 600

DLTGNPRLVL DHKTLELLNN IRCFKIDQPS AGDASGAPAV WSHGYTEASG VKNKLCVAAL 660

SANNFCDNRE ALYGVFDGDR NVEVPYLLQC TMSDILAEEL QKTKSEEEYM INTFIVMQRK 720

LGTAGQKLGG SAVLCHIKHD PMDPGGCFTL TSANVGKCQT VLCRNGKPLP LSRSYVMSCE 780

EELKRIKQHK AIITEDGKVN GVTDSTRILG YTFLHPSVVP RPHVQSITLT PQDEFFILGS 840

KGLWDSLSTE EAVEAVRNVP EPLAAAKKLC TLAQSYGYND SISAVVVQLN VTEDSFCCCE 900

LNGVPPPSPG IFPQSVNVVI KDRPTDALGM PSSSSGMASE ISSEISTSEM SSEVGSTASD 960

EPPQVALNEN SPAYPNEQRC MLHPVCLANS FQRQLSSATF SSAFSDNGLD SDDEEPIEGV 1020

FTNGSRVEVE VDIHCSRAKE KQLLHVPVEA SDEGIVISAN EDETGLSRKA DYSATGTIGR 1080

RRGNGSVAPQ EGSHNLIEVA ADAPLRKTGG YFAAPAQPDP DDQFIIPPEL EEEVKEIMKQ 1140

HQEQQQQQQQ QQQQRQYQMD QLPDYYDTPL 1170

Nucleotide Sequence
(FASTA)

TCAGGAAAGC CCCACAGCAC TGGCAACTCT GAACGGATTC AGCTCTCAGG AATGTACAAT 60

GTTCGAAAAG GGAAAATGCA TTTGCCAGTC AACAGATGGA CAAGGCGCCA AGTTATCCTT 120

TGTGGGACGT GCCTAATCGT ATCATCGGTG AAAGAAAGCC AAACTGGAAA GATGCACGTT 180

CTCCCTCTAA TTGGTGGAAA AGTGGAAGAA GTGAAAAAGC ACCAGCACTG TTTAGCATTT 240

AGTTCCTCTG GACCTCAGAG CCAGACCTAT TACATTTGTT TTGATACCTT CACAGAGTAC 300

TTACGGTGGC TTCGACAAGC ATCAAAGGTT GCATCACAGC GCATCAGTTC AGTGGATCTC 360

TCATGTTGCA GCTTGGAGCA TCTTCCTGCC AACCTCTTCT ACAGCCAGGA CCTCACACAT 420

CTCAATTTAA AACAGAACTT CCTGAGGCTA AATCCTAGTG TGTCAACAAC CAGAGGGCTT 480

AGTGAACTAC AAAGGTTCAC AAAGTTGAAG AGCCTTAACC TTTCCAATAA TAATTTAGGA 540

GACTTCCCGT TGGCAGTTTG CAGTATTCCA ACTCTGACTG AACTCAATGT GTCCTGTAAT 600

GCCCTCAAAA GCATTCCAGC AGCAGTAGGT GATATGCACA ATTTGCAGAC ACTTTTGCTG 660

GATGGTAACT TTCTTCACTC CCTTCCTAAT TATCTGAGTC TTTCATTCAA TGAATTCACT 720

GACATTCCAG GAGTACTAGA GAAGCTAAAT GGCATGGATA AACTCTGTAT GTCTGGAAAC 780

TGTATGGAGA CACTCAGTCT ACAGGCATTA AGAAGAATGC CACATATTAA ACATGTGGAT 840

CTAAGATTGA ATGTAATTAG GAGGCTGGTG GTGGATGAAG TTGACTTCCT GCATCATGTG 900

ACTCAGTTAG ATCTACGGGA CAATAAACTC TGTGAACTAG ATGCAACAAT TTTCAACAAC 960

ATTGAAGTGC TACACTGTGA AAGAAACCAT CTGGTGACCC TCAAAATCAG TGGATATTTT 1020

CTCAAAGCTC TTTATGCCTT TTCAAATGAA CTTGTTCATC TTGATGTATA TCCTGTTCCA 1080

AATTATCTGA CCTCCATGGA TATTTCTAGA AACCACTTGG AAAGCCTGCC TGAGTGGGTA 1140

TGTGACAGCA GGAAGCTAGA AGTGTTGGAT GTTGGCCACA ATCAACTATG TGAACTGCCT 1200

ACCCGGTTGT TTTGCAGTAG TAGTTTGCGT AAGCTTCTAT CAGGACATAA CCAATTAGGA 1260

AGGCTACCGG AAAGGTTTGA AAGAACACAA CTGGAGGTCC TCGATGTGCA ACACAACCAG 1320

CTCCTAGAGC TCCCATCAAA CCTTCTTCTG AAAGCTGACA GCTTGAGAAG CTTGAATGCC 1380

TCTGCCAACA AACTCGAAAC ACTCCCTCCA GCCACCCTGT CTGAGGAGAC CAACAGCATC 1440

TTGCAGGAAC TTTATTTGAC CAATAACAAC CTCACAGATA AATGTGTGCC CTTGTTAACA 1500

GGCCATCCAC ACCTAAAGAT CCTTCATATG GCCTACAATC GGTTACAGAG CTTTCCTGCA 1560

AGTAAAATGG CCAAGCTTGA GGAGTTGGAA GAAATTGATA TTAGCGGGAA CAAACTGAAA 1620

GCCATTCCAA CAACCATTAT GAACTGTAGA CGGATGCATA CTGTGATTGC TCACTCCAAC 1680

TGCATTGAAG TCTTCCCAGA AGTCATGCAA CTTGTTGAAA TAAAGTGTGT GGACCTGAGC 1740

TGCAATGAAC TGAGTGAAAT CACATTACCT GAAAACCTGC CTCCAAAACT ACAGGAACTA 1800

GACCTGACTG GAAACCCCCG ACTAGTCCTA GATCACAAAA CTCTAGAGTT GCTGAATAAC 1860

ATTCGTTGTT TCAAGATTGA CCAACCCTCA GCTGGTGATG CTTCAGGGGC CCCAGCAGTG 1920

TGGAGTCACG GTTATACTGA AGCTTCCGGA GTTAAGAACA AATTGTGTGT GGCAGCTCTT 1980

TCAGCCAATA ATTTCTGTGA CAACAGGGAG GCACTGTATG GAGTCTTTGA TGGTGATCGC 2040

AATGTGGAAG TGCCCTACCT CCTGCAATGT ACAATGAGTG ACATCTTGGC AGAAGAGCTG 2100

CAGAAGACGA AGAGTGAAGA GGAATACATG ATCAACACTT TCATCGTTAT GCAGAGGAAA 2160

CTTGGAACTG CTGGACAAAA ACTTGGAGGC TCTGCTGTCC TTTGCCATAT AAAACATGAT 2220

CCCATGGACC CAGGTGGATG CTTCACATTA ACTTCAGCAA ATGTGGGGAA GTGCCAAACC 2280

GTTCTCTGTA GGAATGGAAA ACCTTTGCCT TTGTCCAGGT CTTATGTGAT GAGTTGTGAA 2340

GAAGAGCTAA AGAGGATTAA ACAGCACAAG GCCATTATCA CAGAGGATGG CAAAGTAAAT 2400

GGGGTGACCG ATTCCACAAG AATCTTGGGA TACACCTTCC TTCACCCAAG CGTTGTGCCC 2460

CGCCCTCACG TCCAGTCCAT TACCTTGACT CCACAAGATG AGTTCTTCAT TCTGGGTAGC 2520

AAGGGATTGT GGGACAGCCT GTCCACTGAG GAGGCGGTGG AAGCCGTCAG AAATGTGCCT 2580

GAACCACTGG CAGCTGCAAA GAAGCTTTGC ACTTTGGCCC AGAGCTATGG CTACAATGAC 2640

AGCATCAGTG CTGTGGTGGT TCAGCTCAAT GTGACTGAGG ACAGCTTTTG CTGCTGTGAG 2700

CTTAATGGAG TCCCACCTCC CAGCCCGGGC ATCTTTCCCC AGTCAGTCAA TGTAGTCATT 2760

AAAGACAGAC CTACAGATGC TTTGGGAATG CCATCTTCCA GCAGCGGGAT GGCCTCTGAG 2820

ATCAGCAGCG AGATCTCCAC TTCTGAAATG AGCAGCGAGG TGGGGTCCAC AGCCTCTGAT 2880

GAGCCCCCTC AAGTAGCCCT GAATGAGAAC AGCCCAGCCT ACCCCAATGA GCAGCGCTGC 2940

ATGCTTCACC CAGTCTGCCT GGCCAATTCT TTCCAAAGGC AGTTATCCAG CGCTACCTTC 3000

TCCAGTGCTT TTTCTGACAA TGGCCTTGAC AGTGATGACG AGGAGCCGAT CGAGGGTGTC 3060

TTCACCAACG GCAGCCGGGT AGAAGTGGAG GTGGACATCC ACTGTAGCCG AGCGAAGGAG 3120

AAACAGCTGC TCCACGTCCC TGTGGAAGCC AGCGATGAAG GCATCGTCAT TAGTGCAAAT 3180

GAGGATGAAA CTGGCCTTTC CAGGAAAGCA GATTACTCAG CCACTGGTAC AATTGGGCGG 3240

CGACGGGGCA ATGGGTCTGT GGCTCCTCAG GAAGGGAGCC ATAACTTGAT TGAAGTAGCG 3300

GCCGATGCAC CTCTCAGAAA AACGGGGGGC TACTTTGCAG CCCCAGCCCA ACCAGATCCA 3360

GATGACCAAT TCATCATCCC GCCAGAGCTT GAAGAAGAGG TAAAGGAGAT TATGAAACAA 3420

CACCAGGAAC AACAACAACA ACAACAACAG CAGCAGCAGC AGCGGCAGTA TCAGATGGAT 3480

CAACTGCCAG ACTATTATGA TACACCATTA TGA 3513

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 642   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  696

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    +++  ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 697   AEELQ----KTKSEEEYMINTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  746

         ***99....9999999*************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv+

Q: 747   cfTLTSANVGKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKQHKAIITEDG--KVNGVTD  804

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr+v e

Q: 805   STRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSTEEAVEAVRNVPE---  861

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g +d++sa+vv

Q: 862   -PLAAAKKLCTLAQSYGYNDSISAVVV  887

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKSEEEYMI NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR 180

PHVQSITLTP QDEFFILGSK GLWDSLSTEE AVEAVRNVPE PLAAAKKLCT LAQSYGYNDS 240

ISAVVV 246

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>