EKS-PES-00357

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00357

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	574.8	7.1E-173	565	899	335

Status

Unreviewed

Ensembl Protein

ENSPSIP00000009260

UniProt Accession

K7FMK0;

Protein Name

Protein Synonyms/Alias

Gene Name

KIT

Gene Synonyms/Alias

KIT;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000008233	ENSPSIP00000009260	ENSPSIT00000009306

Organism

Pelodiscus sinensis

Functional Description

Protein Length

947

Protein Sequence
(FASTA)

MYFVFLPGGT IPSITPGKSS LVVNSGQEVR LICNDDGPVT WDFQNSEPLA KPRHFNNKEW 60

YLKNASAKDT GRYICKNKES LNTSIYVFVK DQHKLFLAES ESFFYVKEDS DILVACPVTD 120

PDVSDFTLKL CGGKPFPENL TFISNPQKGI IIKNVQRSFK GCYQCSGKQN GVEKTSENKY 180

LIVRPVHKTL PVITLSKPSQ LLKEGEEFEV TCTITDVDSS LQANWIPQNN TTVKTKSKNV 240

GDYGYEKKLT LSIRSVGVND SGAFTCQARN PFGTSNVTIT LNVLDKGFVN VSTMKNTTID 300

VNAGENLNLI VEYEAYPRPE EEVWLYMNET LHNSSDHYVK FKTVGNNRYR SELHLTRLKG 360

TEGGIYTFFV SNSDAKSSIT FNVYVNTKPE ILTSDRLSNG MLQCVAAGFP APTIDWYFCP 420

GTEQRCFDSP AISPVDVKIS YRNSSVPSFG RIVVESTIDA STFRNNGTIS CEASNDVARS 480

SAFFNFAIKE HISTHTLFTP LLIGFGVAAG LMCIIVMILM YKYLQKPKYE VQWKVVEEIN 540

GNNYVYIDPT QLPYDQKWEF PRNRLSFGKT LGAGAFGKVV EATAYGLFKS DAAMTVAVKM 600

LKPSAHLTER EALMSELKVL SYLGNHINIV NLLGACTIGG PTLVITEYCC YGDLLNFLRR 660

KRDSFICPKH DECAETAAYE NLLHQKESAC DVINEYMDMK PGVSYVVPPK ADKRRSGRTG 720

SYIDRDVTIA ILEDDELALD VEDLLSFSYQ VAKGMSFLAS KNCIHRDLAA RNILLTHGRI 780

TKICDFGLAR DIKNDSNYVV KGNARLPVKW MAPESIFNCV YTFESDVWSY GILLWELFSL 840

GSSPYPGMPV DSKFYKMIKE GYRMFSPECA PVEMYEIMKS CWDADPVQRP TFKQIVQLIE 900

QQLSDNGNHA YSNFTPHQVN AADHSVRINS VGSSASSTQP LLVREDA 947

Nucleotide Sequence
(FASTA)

ATGTATTTTG TTTTTCTGCC AGGTGGTACA ATACCTTCCA TTACTCCAGG AAAATCTTCC 60

TTAGTTGTGA ATAGTGGACA AGAAGTAAGA CTGATTTGCA ACGATGATGG TCCAGTGACT 120

TGGGATTTTC AGAATTCAGA ACCTTTGGCA AAACCAAGAC ATTTCAATAA TAAAGAATGG 180

TACTTAAAAA ATGCATCAGC CAAAGACACA GGCAGATACA TATGCAAAAA CAAAGAGAGT 240

TTGAACACTT CTATATATGT TTTCGTTAAA GATCAACATA AGCTTTTCCT TGCTGAATCT 300

GAGTCTTTCT TCTATGTCAA AGAAGACAGT GATATTCTTG TGGCATGTCC AGTGACAGAT 360

CCGGATGTTT CAGATTTCAC CTTGAAATTA TGTGGTGGCA AACCATTCCC CGAAAATTTG 420

ACATTTATTT CCAATCCCCA AAAAGGAATA ATTATTAAAA ATGTACAGAG ATCATTTAAA 480

GGGTGCTATC AATGCTCAGG AAAACAAAAT GGAGTTGAGA AAACTTCAGA AAATAAATAC 540

TTGATTGTAA GGCCAGTTCA CAAAACCCTC CCAGTTATCA CCTTATCCAA ACCCAGCCAG 600

CTTCTCAAAG AAGGGGAAGA ATTTGAAGTT ACATGCACAA TAACAGATGT AGATAGCTCG 660

TTGCAAGCTA ATTGGATTCC TCAAAATAAC ACGACTGTTA AAACCAAAAG CAAGAATGTG 720

GGTGATTATG GATATGAAAA GAAATTAACA TTGAGCATCC GTTCAGTGGG AGTTAATGAT 780

TCTGGAGCAT TCACATGCCA AGCAAGAAAC CCTTTTGGAA CATCCAATGT CACAATAACC 840

TTGAATGTAC TAGATAAAGG ATTTGTCAAT GTGTCTACTA TGAAGAATAC AACAATAGAT 900

GTGAATGCTG GAGAAAATTT AAATTTAATA GTTGAGTATG AGGCTTATCC AAGACCAGAA 960

GAAGAAGTGT GGTTATATAT GAATGAAACA TTACACAATT CATCTGATCA TTATGTCAAA 1020

TTCAAGACTG TGGGCAATAA CAGATATAGG AGTGAGCTTC ACCTTACCAG ACTAAAAGGA 1080

ACAGAAGGAG GCATTTACAC ATTTTTTGTA TCCAATTCTG ATGCCAAGTC CTCTATAACA 1140

TTTAATGTCT ATGTGAACAC AAAACCAGAG ATTCTCACTT CAGACAGACT TAGCAATGGC 1200

ATGCTCCAGT GTGTGGCTGC TGGCTTCCCT GCCCCTACTA TAGATTGGTA TTTTTGTCCA 1260

GGAACTGAGC AAAGATGTTT TGATTCACCA GCTATATCTC CAGTGGATGT GAAGATCAGT 1320

TATAGAAATT CATCAGTTCC ATCATTTGGA AGAATAGTAG TTGAAAGTAC CATTGATGCC 1380

AGCACGTTCA GAAACAATGG CACCATTTCA TGTGAGGCTT CCAATGATGT TGCCAGAAGT 1440

TCTGCTTTTT TCAATTTTGC AATTAAAGAA CATATCAGTA CCCACACCCT CTTCACTCCT 1500

TTACTGATAG GGTTTGGAGT TGCAGCAGGA CTGATGTGCA TCATAGTAAT GATTCTCATG 1560

TACAAATATT TACAGAAACC CAAATATGAA GTTCAGTGGA AAGTCGTTGA AGAAATAAAT 1620

GGAAACAACT ATGTTTACAT AGACCCAACA CAACTTCCTT ATGATCAAAA ATGGGAGTTT 1680

CCTAGAAATC GATTGAGTTT TGGTAAAACT CTTGGTGCTG GAGCTTTTGG GAAAGTTGTG 1740

GAGGCTACTG CATATGGTCT GTTTAAATCT GATGCTGCAA TGACAGTAGC AGTAAAAATG 1800

CTCAAACCAA GTGCCCATTT AACGGAGAGG GAAGCATTAA TGTCTGAGCT CAAAGTTCTA 1860

AGTTACCTTG GTAACCATAT TAATATTGTG AATCTTCTTG GAGCCTGCAC GATTGGAGGT 1920

CCCACTCTGG TCATCACGGA ATATTGCTGC TATGGTGATC TTTTGAATTT TCTGAGAAGG 1980

AAACGCGATT CATTTATTTG CCCAAAGCAT GACGAATGTG CAGAAACGGC AGCTTATGAG 2040

AACCTTCTGC ATCAAAAAGA GTCTGCATGT GATGTCATCA ATGAATACAT GGACATGAAA 2100

CCAGGAGTCT CTTATGTTGT TCCACCAAAA GCAGATAAAA GAAGATCAGG GAGGACAGGA 2160

TCATATATTG ATCGAGACGT TACCATTGCA ATATTAGAAG ATGATGAATT AGCTCTGGAT 2220

GTTGAAGATC TACTGAGTTT TTCTTATCAG GTGGCTAAGG GCATGAGCTT CCTTGCCTCC 2280

AAAAACTGCA TTCATAGGGA TTTGGCGGCA AGAAACATTC TTCTCACTCA TGGTCGAATA 2340

ACAAAAATTT GTGACTTTGG CCTTGCTAGA GATATCAAGA ATGACTCAAA TTATGTAGTC 2400

AAAGGAAATG CTCGGCTTCC TGTAAAGTGG ATGGCTCCTG AAAGTATTTT CAACTGTGTA 2460

TATACCTTTG AGAGCGATGT CTGGTCTTAC GGAATATTAC TTTGGGAACT GTTTTCTTTA 2520

GGAAGCAGCC CTTACCCTGG AATGCCTGTG GACTCCAAGT TTTATAAAAT GATTAAGGAA 2580

GGATACAGAA TGTTTAGTCC AGAATGTGCA CCTGTTGAAA TGTATGAGAT AATGAAGAGT 2640

TGCTGGGATG CTGATCCTGT ACAGAGACCA ACATTTAAGC AAATTGTACA GCTAATTGAG 2700

CAGCAGCTTT CAGATAATGG AAACCATGCT TACTCTAACT TTACACCCCA TCAAGTTAAT 2760

GCTGCAGATC ACTCAGTGAG GATTAATTCT GTGGGAAGCA GCGCTTCATC TACTCAGCCC 2820

CTTCTGGTTC GTGAAGATGC TTGA 2844

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         l++Gk+lG+GafGkvveatayGl ksda+++vavkmlk++a+ +e+ealmselk+ls+lG

Q: 565   LSFGKTLGAGAFGKVVEATAYGLFKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLG  624

         79**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeeldska  120

         +h nivnllGact gGp++viteyccyGdlln+lrrkr+sf+   + k+ e +e + +++

Q: 625   NHINIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFI---CPKHDECAETAAYEN  681

         ******************************************...556666777788887

S: 121   lladkslrsksslssesseeyvdlkkdvsdvssskadklasekkksalerevkaaleeed  180

         l     l++k+s   +  +ey+d+k++vs+v + kadk++s ++ s+++r+v+ a+ e+d

Q: 682   L-----LHQKESA-CDVINEYMDMKPGVSYVVPPKADKRRSGRTGSYIDRDVTIAILEDD  735

         7.....5655555.5999******************************************

S: 181   sevleledllsfsyqvakGmeflaskncvhrdlaarnvllteGkvvkicdfGlardimkd  240

         + +l++edllsfsyqvakGm flasknc+hrdlaarn+llt+G+++kicdfGlardi++d

Q: 736   ELALDVEDLLSFSYQVAKGMSFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKND  795

         ************************************************************

S: 241   snyvvkGnarlpvkwmapesifdslytvksdvwsyGillweifslGstpypgllvdskfy  300

         snyvvkGnarlpvkwmapesif+++yt++sdvwsyGillwe+fslGs+pypg++vdskfy

Q: 796   SNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGILLWELFSLGSSPYPGMPVDSKFY  855

         ************************************************************

S: 301   klikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlvell  344

         k+ikeGyrm +p+ a+ e+yeim++cw+a+p +rp+fkq+v+l+

Q: 856   KMIKEGYRMFSPECAPVEMYEIMKSCWDADPVQRPTFKQIVQLI  899

         *****************************************996

Domain Sequence
(FASTA)

LSFGKTLGAG AFGKVVEATA YGLFKSDAAM TVAVKMLKPS AHLTEREALM SELKVLSYLG 60

NHINIVNLLG ACTIGGPTLV ITEYCCYGDL LNFLRRKRDS FICPKHDECA ETAAYENLLH 120

QKESACDVIN EYMDMKPGVS YVVPPKADKR RSGRTGSYID RDVTIAILED DELALDVEDL 180

LSFSYQVAKG MSFLASKNCI HRDLAARNIL LTHGRITKIC DFGLARDIKN DSNYVVKGNA 240

RLPVKWMAPE SIFNCVYTFE SDVWSYGILL WELFSLGSSP YPGMPVDSKF YKMIKEGYRM 300

FSPECAPVEM YEIMKSCWDA DPVQRPTFKQ IVQLI 335

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>