EKS-PES-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Jak	327.2	8.6E-98	878	1150	273

Status

Unreviewed

Ensembl Protein

ENSPSIP00000010631

UniProt Accession

K7FRF6;

Protein Name

Protein Synonyms/Alias

Gene Name

JAK1

Gene Synonyms/Alias

JAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000009400	ENSPSIP00000010631	ENSPSIT00000010684
ENSPSIG00000009400	ENSPSIP00000010616	ENSPSIT00000010669

Organism

Pelodiscus sinensis

Functional Description

Protein Length

1159

Protein Sequence
(FASTA)

MQYLNVKEDC KAMAFCAKLR NSKKSEVTTE AREQGLEIVF YLQEKPPIWY TSGEYTAEDL 60

CIEAAQKCAV SPLCHNLFAL FEESRKLWYA PNHVFKIDDK TALRLYYRMR FYFTNWHGTS 120

ENEPSVWRHS PKKKQKNSYE KKLVPDGTPI LDANSLEYLF AQGQYDLVKC LAPVRDPKND 180

QEVHEIENEC LGMAVLAISH YAIKKNMKLP ELPKDISYKR YIPETLNKTI RQRNILTRIR 240

INNVFKDFLK EFNNKTICDS SVSPHDLKVK YLSTMETLTK HYGAEIFETS SLQISTENEK 300

HGFNLGDNGI MPQYEVMVTG NNGIQWRRKP NVIQPEREKH NKLKRKKMDS KNRKGEEKNK 360

SREEWNSFSY FPEITLLVIK ESTININKQN HEKMEIKLSS HEEALSFASL VDGYFRLTAD 420

AHLYLCTDVA PPLIVHNIRN GCHGPICTEY AINKLRQEGN EEGMYVLRWS CTDFNHILMT 480

VTCSEISQQR LNESVQYKNF QIEVTKDGCF LHGPNKFFPS LKELMDHLKG QTLRTDNISF 540

TLKRCCQPKP KEISNLLVAT KKGQEWHPVC PLGQLSFHRI LKEEILQEEH LGRGTRTQIY 600

SGILNYKADE NDGYQDEKEK KVLLKVLDPS HRDISLAFFE TASMMRQICH KHIVFLHGVC 660

VRDVENIMVE EFVEFGPLDL FMHRKSDVLT TPWKFKVAKQ LASALSYLED KELVHGNVCT 720

KNILLAREGI DHEYGPFIKL SDPGIPITVL SRQECVERIP WIAPECVEDS KNLSVAADKW 780

SFGTTLWEIC YNGEAPLKDK TLAEKERFYE GHFMLVTPSC KELADLMKQC MNYDPNQRPF 840

FRAIMRDINK VEEQNPDIVS EKTPFAEVDP TLFEKRFLKR IRDLGEGHFG KVELCRYDPE 900

GDNTGEQVAV KSLKPESGGN HIADLKKEIE ILRNLYHENI VKYKGICIED GGSGIKLIME 960

FLPSGSLKEY LPRNKSKITL KHQLRYAVQI CKGMDYLGSR QYVHRDLAAR NVLVESENRV 1020

KIGDFGLTKV IETNKEYYTV KDDLDSPVFW YAPECLLQSK FYIASDVWSF GVTLYELLTY 1080

CDSESSPMAE FLKMIGPTQG QMTVTRLVRV LGEGKRLPRP PNCPEEVDQL MRKCWINNPG 1140

DRTTFQNLIQ GFEALINKL 1159

Nucleotide Sequence
(FASTA)

ATGCAGTATC TAAATGTAAA AGAGGATTGC AAAGCCATGG CTTTCTGTGC AAAACTGAGA 60

AACTCAAAAA AAAGTGAAGT GACCACAGAA GCACGAGAGC AGGGATTGGA AATCGTATTC 120

TATTTGCAAG AGAAGCCTCC CATTTGGTAT ACCAGTGGCG AGTACACAGC AGAAGACCTG 180

TGTATTGAAG CTGCCCAGAA GTGCGCTGTA TCTCCATTGT GCCACAATCT CTTTGCGCTA 240

TTTGAGGAGA GTAGAAAACT CTGGTATGCA CCGAACCATG TTTTCAAAAT AGATGACAAG 300

ACAGCCCTCC GACTCTATTA TCGCATGAGG TTTTATTTTA CAAACTGGCA TGGGACAAGT 360

GAAAACGAGC CATCAGTCTG GAGGCATTCT CCAAAAAAAA AACAAAAGAA TTCTTATGAG 420

AAGAAACTAG TGCCAGATGG AACCCCTATC CTTGATGCAA ATTCATTAGA ATATCTCTTT 480

GCACAGGGAC AGTATGATTT GGTGAAGTGC CTGGCACCAG TTCGAGACCC TAAAAATGAT 540

CAGGAGGTTC ATGAAATTGA AAATGAATGT CTGGGAATGG CTGTCCTTGC AATCTCGCAC 600

TATGCCATCA AGAAAAATAT GAAGCTACCA GAGCTTCCCA AGGATATCAG TTACAAACGC 660

TATATTCCTG AAACTTTGAA TAAGACCATC AGACAAAGGA ATATCTTAAC GAGAATTCGG 720

ATAAATAATG TTTTCAAGGA TTTCCTTAAG GAGTTCAATA ATAAAACCAT TTGTGACAGC 780

AGTGTCTCTC CGCATGATCT GAAGGTTAAA TACTTATCAA CAATGGAGAC TTTAACTAAG 840

CATTATGGAG CAGAAATTTT TGAGACTTCA TCATTGCAGA TTTCAACAGA GAATGAAAAA 900

CATGGATTTA ATTTGGGAGA CAATGGGATC ATGCCACAAT ATGAAGTGAT GGTGACAGGA 960

AACAATGGAA TACAGTGGAG GCGCAAACCA AATGTTATAC AGCCTGAAAG AGAGAAACAT 1020

AATAAACTGA AGAGGAAAAA AATGGACAGC AAAAACAGGA AAGGTGAAGA AAAAAACAAA 1080

AGCCGAGAGG AGTGGAACAG TTTTTCATAT TTTCCTGAAA TCACACTACT TGTCATAAAG 1140

GAGTCCACAA TCAATATTAA CAAGCAGAAT CATGAAAAGA TGGAAATAAA ACTTTCTTCA 1200

CACGAGGAGG CCTTGTCATT TGCATCTTTA GTAGATGGAT ACTTCAGACT TACTGCAGAT 1260

GCCCACCTCT ATCTCTGCAC TGATGTAGCT CCACCTTTGA TAGTGCACAA CATAAGAAAT 1320

GGCTGTCATG GACCCATTTG CACAGAGTAT GCCATCAACA AATTAAGACA AGAAGGGAAT 1380

GAGGAGGGGA TGTATGTGCT GAGGTGGAGC TGTACAGACT TTAATCACAT CCTCATGACA 1440

GTGACATGTT CTGAAATCTC TCAGCAAAGA CTAAATGAGT CAGTCCAGTA CAAGAACTTC 1500

CAGATCGAGG TGACAAAAGA TGGTTGCTTC CTTCATGGTC CAAATAAGTT TTTCCCATCT 1560

TTAAAAGAAC TGATGGATCA CTTGAAGGGA CAGACCCTTA GAACGGATAA CATAAGCTTT 1620

ACGCTGAAGA GATGCTGCCA GCCAAAACCA AAAGAAATCT CAAACTTGTT AGTGGCAACA 1680

AAGAAAGGCC AGGAATGGCA TCCTGTTTGC CCTCTAGGTC AACTGAGTTT CCATCGAATC 1740

CTCAAAGAAG AAATTCTGCA GGAAGAACAC CTTGGAAGAG GAACAAGAAC ACAAATTTAC 1800

TCTGGGATTC TCAATTATAA GGCAGATGAG AATGACGGGT ACCAGGATGA AAAAGAGAAA 1860

AAAGTCCTCC TCAAAGTCTT GGACCCCAGT CACAGAGACA TTTCTTTGGC ATTTTTTGAG 1920

ACAGCAAGCA TGATGAGGCA AATTTGCCAC AAACACATCG TCTTCCTTCA TGGGGTCTGT 1980

GTCCGTGATG TAGAAAATAT CATGGTTGAA GAGTTTGTTG AATTTGGACC ACTGGATCTC 2040

TTTATGCACC GGAAAAGTGA TGTTCTTACA ACTCCTTGGA AATTCAAAGT AGCCAAACAG 2100

CTGGCAAGTG CATTAAGCTA CTTGGAGGAT AAAGAGTTGG TACACGGGAA TGTTTGCACA 2160

AAAAATATAC TGTTGGCAAG AGAGGGAATT GACCATGAAT ATGGTCCTTT CATTAAACTG 2220

AGTGACCCAG GAATTCCAAT AACTGTGCTA TCCAGACAAG AATGTGTTGA ACGAATCCCT 2280

TGGATTGCAC CTGAATGTGT TGAAGATTCA AAAAATTTAA GTGTTGCAGC AGATAAGTGG 2340

AGTTTTGGCA CAACACTGTG GGAAATCTGC TACAATGGAG AAGCACCCCT GAAAGATAAG 2400

ACGTTAGCAG AGAAGGAGAG ATTCTATGAA GGGCATTTCA TGTTGGTAAC ACCATCCTGT 2460

AAGGAACTAG CTGATCTCAT GAAGCAGTGC ATGAACTATG ACCCCAATCA GAGGCCATTT 2520

TTCAGAGCCA TTATGAGAGA CATCAATAAA GTGGAAGAAC AAAATCCTGA TATTGTCTCT 2580

GAGAAGACAC CATTTGCTGA AGTTGATCCT ACTCTCTTTG AAAAACGGTT TTTGAAAAGA 2640

ATCCGAGATT TGGGAGAGGG TCACTTTGGC AAAGTTGAAC TCTGCAGGTA TGATCCAGAA 2700

GGTGATAATA CAGGAGAGCA GGTGGCAGTC AAGTCTCTGA AACCTGAGAG TGGTGGAAAT 2760

CATATCGCTG ATCTGAAGAA AGAAATTGAA ATCTTGAGGA ATCTTTATCA TGAAAACATT 2820

GTCAAATACA AAGGAATTTG CATAGAAGAT GGAGGAAGTG GGATCAAACT CATAATGGAG 2880

TTTCTTCCAT CTGGAAGCCT AAAGGAATAT CTCCCACGAA ATAAGAGCAA AATCACTCTC 2940

AAACATCAGC TCCGTTATGC AGTTCAGATC TGCAAGGGAA TGGATTATTT GGGCTCTCGT 3000

CAGTATGTTC ACCGGGATTT AGCAGCAAGA AATGTCCTAG TTGAAAGTGA GAACCGAGTG 3060

AAGATTGGGG ATTTTGGCCT CACCAAAGTA ATTGAAACCA ATAAGGAGTA CTACACGGTC 3120

AAAGATGATC TCGACAGTCC TGTGTTTTGG TATGCTCCAG AATGTCTGCT TCAGAGCAAG 3180

TTTTATATTG CTTCAGATGT CTGGTCATTT GGAGTGACGC TATACGAACT ACTGACCTAC 3240

TGTGATTCAG AGTCCAGTCC AATGGCGGAA TTTTTGAAAA TGATTGGCCC AACTCAAGGC 3300

CAGATGACAG TAACAAGGCT TGTGCGTGTA TTAGGAGAAG GAAAACGCTT GCCACGTCCG 3360

CCAAACTGCC CAGAAGAGGT GGACCAACTG ATGAGGAAAT GTTGGATAAA CAATCCAGGT 3420

GACCGGACGA CCTTTCAAAA TCTTATTCAA GGATTTGAGG CTCTTATAAA TAAATTATAA 3480

Domain Profile

S: 1     lkqiesLgkgtftkvfevredaegdsteeevalkvLk.esgedisrdfkreaeilsqlsh  59

         lk+i++Lg+g+f+kv+++r+d+egd+t+e+va+k Lk esg ++++d+k+e+eil++l+h

Q: 878   LKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKpESGGNHIADLKKEIEILRNLYH  937

         6899********************************************************

S: 60    ehivklkgvcvaegen..rlVmeyvesGsLdiyLrkkkealslsslldvakqlakameYL  117

         e+ivk+kg+c+++g    +l+me+++sGsL++yL+++k +++l+ +l +a q++k+m+YL

Q: 938   ENIVKYKGICIEDGGSgiKLIMEFLPSGSLKEYLPRNKSKITLKHQLRYAVQICKGMDYL  997

         *************9999*******************************************

S: 118   edkklvhrdvaarnvLveresnegtppfvklsdpglakavnqd.eYylvreerdsripwl  176

         +++++vhrd+aarnvLve+e++      vk++d+gl+k+++++ eYy+v+++ ds+++w+

Q: 998   GSRQYVHRDLAARNVLVESENR------VKIGDFGLTKVIETNkEYYTVKDDLDSPVFWY  1051

         **********************......********************************

S: 177   apeclseaknlstasdvWsFgvtlyellt.cskgesp....lrsesle.......rklel  224

         apecl ++k +++asdvWsFgvtlyellt c++++sp    l++++++       r++++

Q: 1052  APECLLQSK-FYIASDVWSFGVTLYELLTyCDSESSPmaefLKMIGPTqgqmtvtRLVRV  1110

         *********.*******************************9999999999*********

S: 225   leekerlpkpk.cpaelaelmtnclsyepsqrpsFraile  263

         l e++rlp+p+ cp+e+ +lm++c+ ++p +r++F+++++

Q: 1111  LGEGKRLPRPPnCPEEVDQLMRKCWINNPGDRTTFQNLIQ  1150

         *************************************986

Domain Sequence
(FASTA)

LKRIRDLGEG HFGKVELCRY DPEGDNTGEQ VAVKSLKPES GGNHIADLKK EIEILRNLYH 60

ENIVKYKGIC IEDGGSGIKL IMEFLPSGSL KEYLPRNKSK ITLKHQLRYA VQICKGMDYL 120

GSRQYVHRDL AARNVLVESE NRVKIGDFGL TKVIETNKEY YTVKDDLDSP VFWYAPECLL 180

QSKFYIASDV WSFGVTLYEL LTYCDSESSP MAEFLKMIGP TQGQMTVTRL VRVLGEGKRL 240

PRPPNCPEEV DQLMRKCWIN NPGDRTTFQN LIQ 273

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>