EKS-PES-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	338.8	2.4E-101	67	376	310

Status

Unreviewed

Ensembl Protein

ENSPSIP00000011967

UniProt Accession

K7FVA7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK8

Gene Synonyms/Alias

CDK8;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000010808	ENSPSIP00000011967	ENSPSIT00000012025

Organism

Pelodiscus sinensis

Functional Description

Protein Length

476

Protein Sequence
(FASTA)

MHAGPGGGLG ALSRLDSTWC FSRCCWGGVA VRAASRRRAL KMDYDFKVKL TGERERVEDL 60

FEYEGCKVGR GTYGHVYKAK RKDGKDDKDY ALKQIEGTGI SMSACREIAL LRELKHPNVI 120

SLQKVFLSHA DRKVWLLFDY AEHDLWHIIK FHRASKANKK PVQLPRGMVK SLLYQILDGI 180

HYLHANWVLH RDLKPANILV MGEGPERGRV KIADMGFARL FNSPLKPLAD LDPVVVTFWY 240

RAPELLLGAR HYTKAIDIWA IGCIFAELLT SEPIFHCRQE DIKTSNPYHH DQLDRIFNVM 300

GFPADKDWED IKKMPEHSTL MKDFRRNTYT NCSLIKYMEK HKVKPDSKAF HLLQKLLTMD 360

PIKRITSEQA MQDPYFLEDP LPTSDVFAGC QIPYPKREFL TEEEPDDKGD KKNQQQQQGN 420

NHTNGTGHPG NQDSSHTQGP PLKKVRVVPP TTTSGGLIMT SDYQISASLC HISNSA 476

Nucleotide Sequence
(FASTA)

ATGCATGCCG GTCCGGGAGG TGGACTGGGC GCTCTCAGCC GGCTAGATTC CACGTGGTGT 60

TTTAGTCGCT GCTGCTGGGG AGGTGTCGCG GTGAGAGCGG CTTCGCGGCG GCGGGCGCTG 120

AAGATGGACT ATGACTTCAA GGTGAAGCTG ACTGGGGAGC GGGAGCGGGT GGAGGACCTG 180

TTCGAGTACG AGGGCTGCAA GGTGGGGAGA GGCACCTACG GGCACGTCTA CAAAGCCAAG 240

CGGAAAGACG GGAAAGATGA TAAAGATTAT GCTTTAAAAC AAATAGAAGG TACTGGAATT 300

TCTATGTCTG CATGCAGAGA AATAGCACTG CTGCGAGAGC TCAAGCATCC AAACGTCATT 360

TCTTTGCAAA AGGTGTTTCT GTCTCATGCT GACAGGAAAG TGTGGCTTCT CTTTGACTAT 420

GCTGAACATG ACCTCTGGCA CATAATCAAG TTTCACAGAG CTTCTAAAGC AAACAAGAAA 480

CCAGTTCAGT TACCTCGGGG AATGGTGAAG TCACTATTAT ATCAGATCCT AGATGGTATT 540

CACTACCTGC ATGCTAACTG GGTGTTACAC AGGGATTTGA AACCTGCTAA TATTTTAGTT 600

ATGGGTGAAG GTCCTGAGCG AGGAAGAGTA AAAATTGCTG ATATGGGCTT TGCCAGATTA 660

TTTAATTCAC CTCTGAAGCC TTTAGCAGAT TTGGATCCAG TAGTTGTAAC GTTCTGGTAC 720

CGAGCTCCAG AATTGCTTCT TGGAGCAAGG CATTATACCA AAGCTATCGA TATTTGGGCG 780

ATAGGGTGTA TATTTGCAGA GCTGCTAACA TCAGAGCCAA TATTCCACTG TCGACAAGAA 840

GACATCAAAA CTAGTAATCC TTATCACCAT GACCAGCTGG ACAGAATATT CAATGTAATG 900

GGATTTCCTG CAGATAAAGA TTGGGAGGAT ATAAAAAAGA TGCCTGAACA TTCAACATTA 960

ATGAAAGATT TCAGAAGAAA CACGTATACC AACTGCAGCC TTATCAAATA TATGGAAAAA 1020

CATAAAGTTA AACCAGATAG TAAGGCATTC CACTTGCTTC AGAAATTGCT TACTATGGAT 1080

CCTATAAAGA GAATTACCTC AGAACAGGCT ATGCAGGATC CTTATTTCTT AGAAGATCCA 1140

CTTCCCACAT CTGATGTTTT TGCAGGTTGT CAGATCCCCT ATCCAAAACG AGAATTTTTA 1200

ACAGAAGAAG AACCCGATGA TAAAGGAGAC AAAAAGAACC AGCAGCAGCA GCAGGGCAAT 1260

AACCATACTA ATGGAACTGG TCATCCAGGG AACCAAGACA GCAGTCATAC ACAGGGACCC 1320

CCATTGAAAA AAGTGAGAGT TGTTCCTCCT ACCACTACCT CAGGTGGACT TATTATGACC 1380

TCAGACTATC AGATCTCAGC AAGCCTCTGC CACATCAGTA ATTCTGCTTG A 1431

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vykak+k+  +++ +AlK+i    e +g++++a+rEi+ll+elkh+n+++L

Q: 67    KVGRGTYGHVYKAKRKDgkDDKDYALKQI----EGTGISMSACREIALLRELKHPNVISL  122

         79************986447778******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k ++++       +l++ +vksll+q+l+g++y

Q: 123   QKVFLsHADRKVWLLFDYAEHDLWHIIKFHRASkankkpvQLPRGMVKSLLYQILDGIHY  182

         ****94555*********************9999999999********************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 183   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  242

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 243   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpyhHDQLDRIFNVMGF  302

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pe++   k+f++++++  +l ++++k k    +ka++ll+kll++dp

Q: 303   PADKDWEDIKKMPEHStlmKDFRRNTYTncSLIKYMEKHKvkpdSKAFHLLQKLLTMDPI  362

         ***************96644777777764455666644333354679*************

S: 271   kRisakealqhkyf  284

         kRi++++a+q++yf

Q: 363   KRITSEQAMQDPYF  376

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKAKRKDGKD DKDYALKQIE GTGISMSACR EIALLRELKH PNVISLQKVF 60

LSHADRKVWL LFDYAEHDLW HIIKFHRASK ANKKPVQLPR GMVKSLLYQI LDGIHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PYHHDQLDRI FNVMGFPADK 240

DWEDIKKMPE HSTLMKDFRR NTYTNCSLIK YMEKHKVKPD SKAFHLLQKL LTMDPIKRIT 300

SEQAMQDPYF 310

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>