EKS-PES-00360

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00360

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	491.4	1.6E-147	550	883	334

Status

Unreviewed

Ensembl Protein

ENSPSIP00000013842

UniProt Accession

K7G0N2;

Protein Name

Protein Synonyms/Alias

Gene Name

FLT3

Gene Synonyms/Alias

FLT3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000012352	ENSPSIP00000013842	ENSPSIT00000013907

Organism

Pelodiscus sinensis

Functional Description

Protein Length

934

Protein Sequence
(FASTA)

EDLGCDLSSQ STENVYESAK NVEVDLFGDI ELKVIMNISE TISCLWVFKE NQADCTPSLD 60

SENRYVISLV FSKIQENQAG KYTLAVQGEN SIYTIIFTVL VRSNILCKPR KPYFVKSENL 120

TIINCMSESY PPPLIEWLFC RTPDDRIELE QLKENGIMHD TLFQTDIQCC ATNELGRECT 180

KLYTIDLNEN LGASLPELLL KVGEPLLIRC RAVYESYAFK LKWYFENREL KKARWFEEST 240

YRKDLSMVRI LYAFASSMGR SDSGHYTCSS TEHPNKTALV TVLEEGFIKV TDSREDFEID 300

LLEKFCFEIK LKVYPPIRCI WISSQQSFPC EQNYSADGYS ISSRFCDHKY QSGEYVFYAE 360

NDDTYVNKTM TLHVKRKPEV IIQSTSKQIT CFSDSYPAPF WTWRKCLGPD FSNCTEEITE 420

GIWRGTPERI TFGSWHSSST LDVQNTMIGF YVECCANNSV GASCVKGFTN QQGAVSSLRD 480

NISFYATIGF CLPFIAVLLI FIFHKYKKQF RYESQMQMIQ VVGPSDNEYI YIDFSEFEYD 540

LKWEFPRENL EFGQALGSGA FGKVMNATAY GISKTGDSVQ VAVKMLKEKS DPSEEDALMS 600

ELKMMTHIGS HENIVNLLGA CTITGNIHCI EIDYCLSSLV LVLLWNKREK FHRTWTDIFK 660

QHNFSFYHNF HLDQNARLDD FGGMQLRRDS DLTSGSNWIT LYSEEEEMKY INRRVYEEED 720

FNVLTFEDLL CFSYQVAKGM EFLESKSCIH RDLAARNVLV TCGKVVKICD FGLARDIMND 780

SNYVIRGNAR LPVKWMAPES LFDRIYTIKS DVWSYGILLW EIFSLGVNPY PGIQVDSNFY 840

KLIQSGFKMD QPFYATEAIY FVMQSCWALD SRKRPFFSQL RPLIERQLVD AEGAVYQNTE 900

NNISTYSSNS KTKSRESRED EPFPSSVPSQ DEDS 934

Nucleotide Sequence
(FASTA)

GAAGATCTTG GTTGTGATTT GAGTTCTCAA AGCACAGAAA ATGTCTATGA ATCAGCAAAA 60

AATGTGGAAG TTGACCTGTT TGGAGACATT GAATTAAAAG TGATAATGAA TATTTCAGAG 120

ACCATTTCAT GCCTTTGGGT CTTCAAAGAG AACCAAGCTG ACTGCACACC CTCACTGGAC 180

TCAGAAAACC GATATGTTAT TTCGCTGGTC TTTTCAAAAA TACAAGAAAA TCAAGCTGGA 240

AAATACACCC TTGCAGTTCA AGGTGAAAAC AGTATCTACA CGATAATATT TACAGTTCTC 300

GTAAGAAGTA ATATTCTCTG TAAACCAAGG AAGCCTTATT TTGTAAAAAG TGAAAATTTG 360

ACCATTATAA ACTGCATGTC TGAAAGCTAC CCTCCACCAC TTATTGAATG GTTATTTTGC 420

AGAACACCTG ATGACAGGAT TGAACTTGAA CAACTGAAGG AGAACGGAAT TATGCATGAT 480

ACGTTATTTC AAACAGACAT ACAGTGCTGC GCAACTAATG AGCTGGGCAG AGAATGCACT 540

AAACTATATA CAATAGATCT AAATGAAAAT CTTGGAGCAT CTTTACCAGA ATTACTTCTT 600

AAAGTTGGGG AACCATTATT AATAAGATGT AGAGCAGTTT ATGAAAGCTA TGCATTCAAA 660

TTGAAATGGT ATTTTGAAAA CAGAGAATTA AAGAAGGCAC GCTGGTTTGA AGAATCAACC 720

TATCGAAAAG ACTTGTCTAT GGTTCGGATT CTCTATGCAT TTGCCTCATC GATGGGACGA 780

AGTGATAGTG GACATTATAC CTGTTCTTCT ACAGAACATC CAAATAAAAC AGCTTTGGTT 840

ACAGTCTTAG AAGAGGGATT TATAAAAGTA ACTGACTCGA GAGAAGATTT TGAGATTGAC 900

CTGTTGGAAA AGTTTTGTTT TGAAATCAAA CTTAAAGTAT ACCCACCAAT CAGATGTATA 960

TGGATTTCTT CCCAACAATC GTTTCCTTGT GAGCAAAATT ACAGTGCAGA TGGATACAGC 1020

ATTTCATCAA GGTTCTGTGA TCATAAATAT CAATCAGGGG AATACGTATT CTATGCAGAA 1080

AATGATGATA CGTATGTGAA TAAAACAATG ACGTTGCATG TAAAACGAAA ACCTGAAGTA 1140

ATCATACAGT CAACATCAAA ACAGATTACT TGCTTCTCTG ATAGTTACCC TGCACCATTT 1200

TGGACTTGGA GGAAATGTCT GGGACCTGAT TTTTCTAATT GTACAGAAGA AATCACAGAA 1260

GGAATTTGGA GAGGAACACC TGAGCGAATA ACCTTTGGGT CCTGGCATTC CAGCAGCACT 1320

TTAGATGTAC AGAATACAAT GATAGGCTTC TATGTGGAGT GCTGTGCAAA CAATTCCGTT 1380

GGCGCATCCT GCGTGAAGGG GTTCACTAAC CAACAAGGAG CTGTTTCTTC CCTCCGAGAT 1440

AACATTTCAT TCTATGCAAC TATCGGATTT TGCCTTCCAT TTATAGCTGT TTTGCTTATA 1500

TTTATTTTTC ATAAATACAA AAAGCAATTT AGATATGAAA GTCAAATGCA AATGATACAG 1560

GTAGTTGGTC CTTCAGATAA TGAGTACATC TACATTGATT TCAGTGAATT TGAATATGAT 1620

CTCAAATGGG AGTTTCCAAG AGAAAATCTG GAATTTGGGC AGGCACTCGG CTCTGGTGCC 1680

TTTGGAAAGG TTATGAATGC TACAGCTTAT GGAATTAGTA AAACCGGGGA TTCAGTCCAA 1740

GTTGCAGTCA AAATGCTGAA AGAAAAATCT GACCCTTCCG AAGAAGATGC TCTAATGTCA 1800

GAACTCAAAA TGATGACTCA TATTGGAAGC CATGAAAACA TTGTAAATCT ATTAGGCGCT 1860

TGCACCATAA CAGGTAATAT ACACTGTATT GAAATAGATT ATTGCTTAAG TTCATTAGTG 1920

CTAGTGCTCC TCTGGAATAA GAGAGAAAAA TTTCACCGGA CGTGGACAGA CATCTTCAAA 1980

CAGCACAATT TCAGCTTTTA CCACAATTTC CACTTGGACC AAAATGCCAG ATTGGATGAT 2040

TTTGGAGGTA TGCAGCTAAG GCGGGACTCA GATTTGACCT CTGGATCAAA CTGGATTACA 2100

TTGTATTCTG AGGAAGAAGA AATGAAATAT ATCAACCGAA GGGTTTATGA AGAGGAGGAC 2160

TTCAATGTGC TCACCTTTGA GGATCTTCTC TGCTTCTCAT ATCAAGTTGC CAAAGGAATG 2220

GAGTTTCTTG AGTCAAAATC GTGCATCCAC AGAGACCTGG CTGCTAGGAA TGTATTAGTG 2280

ACTTGTGGCA AAGTGGTGAA AATATGTGAC TTTGGCCTAG CTAGAGATAT AATGAATGAC 2340

TCTAACTACG TCATCAGAGG CAACGCTCGG TTACCAGTCA AATGGATGGC TCCTGAAAGT 2400

TTATTTGACA GGATTTACAC AATTAAGAGT GATGTCTGGT CTTATGGAAT ATTACTGTGG 2460

GAAATATTCT CTCTCGGTGT GAATCCTTAC CCTGGAATTC AGGTTGATTC AAACTTTTAC 2520

AAACTCATTC AAAGTGGATT TAAAATGGAC CAGCCATTTT ATGCTACAGA AGCAATATAC 2580

TTTGTAATGC AGTCCTGTTG GGCACTGGAC TCTCGAAAAA GGCCCTTCTT TTCACAGCTG 2640

CGTCCTCTCA TAGAACGTCA GCTGGTTGAT GCAGAAGGAG CGGTATATCA AAATACGGAG 2700

AACAATATTT CTACATACTC TTCCAATTCC AAAACCAAAT CACGTGAAAG CAGGGAAGAT 2760

GAACCCTTTC CATCCAGTGT TCCATCCCAG GATGAAGATT CT 2802

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         le+G+ lGsGafGkv++atayG+sk++ +++vavkmlk++++ se +almselk+++h+G

Q: 550   LEFGQALGSGAFGKVMNATAYGISKTGDSVQVAVKMLKEKSDPSEEDALMSELKMMTHIG  609

         79**********************************************************

S: 61    ehenivnllGactkgGpiyvi.teyccyGdllnylrrkresflkkslekkkekeeeldsk  119

         +henivnllGact +G i+ i ++yc    +l  l +kre+f++++++++k+++++++++

Q: 610   SHENIVNLLGACTITGNIHCIeIDYCLSSLVLVLLWNKREKFHRTWTDIFKQHNFSFYHN  669

         ******************988579********************************9998

S: 120   alladkslrsksslssesseeyvdlkkdvsdvssskadklasek.kksalerevkaalee  178

                ++ +++   ++ +  ++l++d++  s s+  +l+se+ + ++++r+v    ee

Q: 670   -------FHLDQNARLDDFGG-MQLRRDSDLTSGSNWITLYSEEeEMKYINRRV---YEE  718

         .......67777777788777.9****999999999888777650445555554...589

S: 179   edsevleledllsfsyqvakGmeflaskncvhrdlaarnvllteGkvvkicdfGlardim  238

         ed +vl++edll+fsyqvakGmefl+sk+c+hrdlaarnvl+t GkvvkicdfGlardim

Q: 719   EDFNVLTFEDLLCFSYQVAKGMEFLESKSCIHRDLAARNVLVTCGKVVKICDFGLARDIM  778

         99**********************************************************

S: 239   kdsnyvvkGnarlpvkwmapesifdslytvksdvwsyGillweifslGstpypgllvdsk  298

         +dsnyv++Gnarlpvkwmapes+fd +yt+ksdvwsyGillweifslG++pypg+ vds+

Q: 779   NDSNYVIRGNARLPVKWMAPESLFDRIYTIKSDVWSYGILLWEIFSLGVNPYPGIQVDSN  838

         ************************************************************

S: 299   fyklikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlvel  343

         fykli++G++m+qp+yate iy +mq+cw+ +++krp f+ql  l

Q: 839   FYKLIQSGFKMDQPFYATEAIYFVMQSCWALDSRKRPFFSQLRPL  883

         *****************************************9766

Domain Sequence
(FASTA)

LEFGQALGSG AFGKVMNATA YGISKTGDSV QVAVKMLKEK SDPSEEDALM SELKMMTHIG 60

SHENIVNLLG ACTITGNIHC IEIDYCLSSL VLVLLWNKRE KFHRTWTDIF KQHNFSFYHN 120

FHLDQNARLD DFGGMQLRRD SDLTSGSNWI TLYSEEEEMK YINRRVYEEE DFNVLTFEDL 180

LCFSYQVAKG MEFLESKSCI HRDLAARNVL VTCGKVVKIC DFGLARDIMN DSNYVIRGNA 240

RLPVKWMAPE SLFDRIYTIK SDVWSYGILL WEIFSLGVNP YPGIQVDSNF YKLIQSGFKM 300

DQPFYATEAI YFVMQSCWAL DSRKRPFFSQ LRPL 334

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>