EKS-PES-00185

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00185

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	461.5	8.1E-139	13	297	285

Status

Unreviewed

Ensembl Protein

ENSPSIP00000014123

UniProt Accession

K7G1G2;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL5

Gene Synonyms/Alias

CDKL5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000012675	ENSPSIP00000014123	ENSPSIT00000014189

Organism

Pelodiscus sinensis

Functional Description

Protein Length

644

Protein Sequence
(FASTA)

MKILNIGNVM NKFEILGVVG EGAYGVVLKC RHKETHEIVA IKKFKDSEEN EEVKETTLRE 60

LKMLRTLKQE NIVELKEAFR RRGKLYLVFE YVEKNMLELL EEMPNGVPPE KVKSYIYQLI 120

KAINWCHKND IVHRDIKPEN LLISHSDVLK LCDFGFARNL SEGSNANYTE YVATRWYRSP 180

ELLLGAPYGK SVDMWSVGCI LGELSDGQPL FPGESEIDQL FTIQKVLGPL PSEQMKLFYS 240

NPRFHGLRFP AVNHPQSLER RYLGILSGVL LDLMKNLLKL DPADRYLTEQ CLNHPSFQTQ 300

RLLDRCGSSP SRSAKRKPYH DSNTLSNRNQ ASKSSVVQSH HRSNSKDMQT LGAGLQRGEE 360

VLPANESFIN GNLPVSAHSP MHTKKPSNPA GSGNKDLANN NMPHLLSPKE SKAKTEFDFN 420

LDPKASDGPG TKYLKSNTRS QQNRHSFMET SQSKTGTLQP SEKHSRHSYI DTIPQSSKSP 480

SYRTKSKNHG VLTDSKSVGN LSEARAQIAE PNSSRYFPSS CLDLNSPTSP TPPRHSDSRT 540

LLSPSGRNNR SDGTLDSRRP STRHSKTMEE LKLPDHMDTS HSHSLSAPHE SFSYGLGYTS 600

PFSSQQRPHR HSMCSIGHSH DLLALHGKTV QKMLIGRVIR SHQR 644

Nucleotide Sequence
(FASTA)

ATGAAGATTC TTAACATTGG TAATGTGATG AATAAATTTG AGATCCTTGG GGTTGTAGGT 60

GAAGGAGCCT ATGGGGTTGT ACTTAAATGC AGACACAAGG AGACACATGA AATTGTGGCT 120

ATCAAGAAAT TCAAAGATAG TGAAGAAAAT GAGGAAGTCA AAGAAACTAC TTTACGAGAG 180

CTTAAAATGC TTCGCACATT GAAACAGGAA AACATAGTGG AGCTGAAGGA AGCCTTCAGA 240

AGAAGAGGAA AATTATACTT AGTGTTTGAA TATGTGGAAA AAAATATGCT TGAGTTGCTA 300

GAAGAAATGC CAAATGGAGT TCCACCTGAA AAAGTAAAAA GCTATATCTA CCAGTTAATC 360

AAAGCAATTA ACTGGTGTCA TAAGAATGAT ATTGTTCATA GAGATATCAA ACCAGAAAAT 420

CTTTTAATAA GCCACTCTGA TGTTCTGAAG TTATGTGACT TTGGCTTTGC TCGGAATCTC 480

TCAGAAGGAA GTAATGCAAA CTATACAGAA TATGTGGCCA CCAGGTGGTA CCGTTCACCT 540

GAACTCTTGC TTGGTGCCCC CTATGGGAAG TCTGTTGATA TGTGGTCTGT TGGCTGCATT 600

CTTGGCGAAC TTAGTGATGG GCAGCCACTG TTTCCTGGAG AAAGTGAAAT TGACCAGCTT 660

TTTACAATTC AGAAGGTGCT AGGACCACTT CCATCAGAGC AGATGAAGCT TTTCTACAGC 720

AATCCTCGTT TTCATGGACT GCGGTTCCCA GCAGTCAACC ATCCTCAATC TTTGGAAAGA 780

AGATACTTAG GAATTTTAAG TGGTGTTTTG CTTGACCTTA TGAAGAACTT GCTGAAGCTG 840

GATCCAGCAG ATAGATACTT GACAGAGCAA TGTTTGAACC ATCCTTCGTT TCAAACTCAG 900

AGACTCTTGG ATCGTTGTGG AAGTTCACCT TCACGATCAG CTAAGAGAAA ACCTTACCAT 960

GACAGCAATA CATTGTCTAA CCGAAATCAA GCCAGCAAAA GCTCTGTTGT ACAGTCACAT 1020

CACAGATCAA ATAGCAAGGA CATGCAGACT CTAGGGGCTG GACTGCAGAG AGGAGAAGAG 1080

GTTCTTCCAG CAAATGAAAG TTTTATAAAT GGAAACCTTC CTGTATCTGC ACACAGTCCA 1140

ATGCATACAA AAAAACCTAG TAACCCAGCT GGATCTGGCA ACAAGGATCT AGCCAACAAC 1200

AACATGCCAC ATCTTCTCAG TCCAAAGGAA TCAAAGGCAA AAACAGAATT TGATTTTAAT 1260

TTGGACCCAA AAGCGTCTGA TGGTCCAGGT ACAAAATACC TGAAGTCAAA CACCAGATCT 1320

CAACAGAACC GGCACTCATT TATGGAAACT TCTCAAAGCA AAACTGGCAC GCTGCAGCCA 1380

AGTGAGAAAC ATAGTCGCCA CAGTTATATT GATACCATTC CCCAGTCTTC AAAGAGTCCT 1440

TCCTATCGGA CAAAGTCAAA GAATCATGGG GTTCTGACAG ACTCAAAATC TGTGGGGAAT 1500

CTTTCTGAGG CCAGAGCTCA AATTGCAGAA CCAAATAGCA GTAGGTATTT TCCATCAAGC 1560

TGCTTGGACT TGAACTCTCC TACCAGTCCT ACACCTCCCC GGCACAGTGA CAGTAGAACT 1620

TTACTCAGTC CTTCAGGGAG AAATAACCGA AGTGATGGTA CCCTTGATTC CCGAAGACCA 1680

TCAACAAGAC ATTCCAAAAC CATGGAAGAG TTGAAGTTGC CAGATCACAT GGATACAAGC 1740

CATTCACATT CATTATCTGC CCCACATGAA TCATTTTCAT ATGGTCTAGG TTACACAAGT 1800

CCCTTTTCCT CACAGCAGCG CCCTCATAGA CATTCCATGT GCAGCATAGG TCACTCACAC 1860

GATCTGTTGG CTCTTCACGG GAAGACTGTA CAGAAGATGC TAATAGGCAG AGTGATCAGA 1920

TCCCACCAGA GATGA 1935

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         +e lg+vGeG+yGvvlkcr+k+t++ivaikkf++se+++evk+++lre+k+l++lk+en+

Q: 13    FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI  72

         799*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+l+e+frr+ klylvfeyv+k++l+ le++pnGv+ e+vk+++yq++kai++chkn+i+

Q: 73    VELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAINWCHKNDIV  132

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGks  179

         hrdikpen+lis+s+v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGks

Q: 133   HRDIKPENLLISHSDVLKLCDFGFARNLSeGSNANYTEYVATRWYRSPELLLG-APYGKS  191

         ****************************98999********************.9*****

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpe  239

         vd+w++Gc+l el++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+

Q: 192   VDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPA  251

         ************************************************************

S: 240   vedleslekkyp.klnevlldllkkclkldpaerlsceellkheyf  284

         v++++sle++y   l+ vlldl+k++lkldpa+r+++e++l+h+ f

Q: 252   VNHPQSLERRYLgILSGVLLDLMKNLLKLDPADRYLTEQCLNHPSF  297

         ***********98899***************************987

Domain Sequence
(FASTA)

FEILGVVGEG AYGVVLKCRH KETHEIVAIK KFKDSEENEE VKETTLRELK MLRTLKQENI 60

VELKEAFRRR GKLYLVFEYV EKNMLELLEE MPNGVPPEKV KSYIYQLIKA INWCHKNDIV 120

HRDIKPENLL ISHSDVLKLC DFGFARNLSE GSNANYTEYV ATRWYRSPEL LLGAPYGKSV 180

DMWSVGCILG ELSDGQPLFP GESEIDQLFT IQKVLGPLPS EQMKLFYSNP RFHGLRFPAV 240

NHPQSLERRY LGILSGVLLD LMKNLLKLDP ADRYLTEQCL NHPSF 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>