EKS-PES-00235

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PES-00235

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	473.3	3.9E-142	219	532	314

Status

Unreviewed

Ensembl Protein

ENSPSIP00000018894

UniProt Accession

K7GF33;

Protein Name

Protein Synonyms/Alias

Gene Name

DYRK2

Gene Synonyms/Alias

DYRK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPSIG00000016789	ENSPSIP00000018894	ENSPSIT00000018980

Organism

Pelodiscus sinensis

Functional Description

Protein Length

598

Protein Sequence
(FASTA)

ERFPCGAAAT GKGRGGGPGG GGRQLQSSPG IGAGGSRTGA GTGPPSPIAL PPLRSSNAAH 60

TSQHTVGGSK HTMNEHLHVG SHGQIQVQQL FEDNSNKRTV LTTQPNGLAA VSKSGLSVVQ 120

DRQIDSAHRQ QGSSSSLKLT DGTGKLKASF MTPEQAMKQY MQKLSAFEHH EIFSYPEIFF 180

LGPNAKKRQG VLGGPNNCGY DDDQGSYVQV PHDHIAYRYE VLKVIGKGSF GQVVKAYDHK 240

THQHVALKMV RNEKRFHRQA AEEIRILEHL RKQDKDNNMN VIHMLENFTF RNHICMTFEL 300

LSMNLYELIK KNKFQGFSLP LVRKFAHSIL QCLDALHKNR IIHCDLKPEN ILLKQQGRSG 360

IKVIDFGSSC YEHQRVYTYI QSRFYRAPEV ILGARYGMPI DMWSLGCILA ELLTGYPLLP 420

GEDEGDQLAC MIELLGMPAQ KLLDSSKRAK NFVSSKGYPR YCTITTLSDG SVILNGGRSR 480

RGKLRGPPES REWGNALKGC DDPLFLDFLK QCLEWDPAIR MTPSQALRHP WLRRRLPKPP 540

TGEKTSAKRL TESTGAIMST SKLPPTSTSA SKLRTNLAQM TDANGNIQQR TVLPKLVS 598

Nucleotide Sequence
(FASTA)

GAGAGATTCC CCTGTGGGGC TGCGGCCACG GGGAAGGGGA GGGGGGGCGG GCCGGGTGGG 60

GGGGGCCGCC AGCTGCAGTC TTCCCCGGGC ATCGGAGCCG GGGGATCCCG GACGGGAGCT 120

GGGACCGGCC CGCCGTCACC CATCGCCTTG CCGCCGCTTA GGTCGAGCAA CGCCGCCCAC 180

ACGAGTCAAC ATACTGTTGG AGGCAGTAAG CACACAATGA ATGAACATCT GCATGTTGGT 240

AGCCACGGAC AGATTCAGGT TCAACAGCTG TTTGAAGATA ATAGCAACAA GAGGACAGTT 300

CTGACAACAC AACCAAATGG GCTTGCAGCA GTAAGCAAAT CTGGATTGTC AGTGGTGCAG 360

GACAGGCAGA TAGACAGTGC TCATAGACAA CAAGGGAGCT CCAGTTCTTT AAAATTAACG 420

GACGGAACAG GGAAGCTGAA AGCCTCTTTT ATGACACCAG AACAAGCAAT GAAGCAATAC 480

ATGCAAAAAC TATCAGCCTT TGAGCACCAT GAAATTTTCA GTTACCCTGA AATATTCTTT 540

TTGGGTCCAA ATGCAAAGAA GCGGCAAGGT GTGCTTGGAG GTCCAAATAA TTGCGGTTAT 600

GATGATGACC AGGGGTCTTA TGTGCAAGTA CCCCATGATC ATATTGCATA CAGGTATGAA 660

GTCCTCAAGG TTATAGGGAA AGGAAGTTTT GGGCAAGTTG TCAAGGCTTA TGATCACAAG 720

ACCCATCAAC ATGTGGCGTT AAAAATGGTA AGAAATGAAA AACGGTTCCA CCGCCAAGCG 780

GCAGAAGAAA TTAGAATTCT GGAGCATCTA AGGAAGCAGG ATAAGGATAA CAACATGAAT 840

GTTATTCACA TGCTGGAAAA CTTTACATTC CGCAACCATA TCTGCATGAC ATTTGAGTTG 900

CTGAGCATGA ACCTTTATGA GCTAATAAAG AAAAACAAAT TTCAGGGCTT CAGCCTGCCA 960

CTAGTTCGGA AGTTTGCCCA CTCGATTTTG CAGTGCTTAG ATGCGTTGCA CAAAAATAGA 1020

ATCATTCACT GTGACCTTAA GCCTGAGAAC ATTCTGTTGA AGCAACAGGG TAGAAGTGGT 1080

ATTAAAGTAA TTGATTTTGG CTCTAGTTGT TATGAGCATC AACGAGTCTA CACTTACATT 1140

CAGTCACGTT TCTACCGTGC TCCAGAAGTG ATCCTTGGTG CTCGTTATGG GATGCCTATT 1200

GATATGTGGA GCCTGGGCTG CATTCTAGCA GAGCTTTTAA CAGGTTACCC ACTCTTACCT 1260

GGAGAAGATG AAGGGGACCA ACTGGCCTGT ATGATAGAGC TACTGGGCAT GCCTGCCCAA 1320

AAACTACTAG ATTCGTCAAA AAGAGCCAAA AATTTTGTGA GCTCTAAAGG TTATCCCCGT 1380

TATTGTACCA TCACCACATT GTCTGACGGT TCTGTAATAC TTAATGGTGG CCGCTCCCGC 1440

AGGGGAAAAT TGCGTGGCCC ACCAGAGAGC AGAGAGTGGG GGAACGCGTT AAAGGGATGT 1500

GATGATCCCC TTTTCCTTGA CTTCTTAAAA CAGTGTTTAG AATGGGATCC TGCTATACGC 1560

ATGACACCCA GCCAGGCTTT ACGGCATCCC TGGCTTAGGA GACGTTTGCC AAAGCCTCCA 1620

ACTGGAGAAA AGACATCGGC AAAGCGATTA ACAGAAAGCA CTGGTGCTAT AATGTCAACT 1680

TCCAAGTTAC CTCCAACGTC AACCTCAGCT TCAAAACTGA GGACTAATTT GGCACAGATG 1740

ACAGATGCCA ATGGGAATAT TCAGCAGAGA ACAGTGTTGC CAAAACTCGT TAGCTGA 1797

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevl+vigkGsfgqVvka+d+kt+++va+k+++n+krf+rqa+eE++iLe+l+k+dk+++

Q: 219   YEVLKVIGKGSFGQVVKAYDHKTHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNN  278

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         +nv+++le f+frnh+c++fells+nLyel+kknkf+g+sl lvrk+a++il++L++L++

Q: 279   MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHK  338

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         ++iiH+DlKPeNill++++rs +kviDFGss++++q+ +ytyiqsrfYraPE+ilg++y

Q: 339   NRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQR-VYTYIQSRFYRAPEVILGARYG  397

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         + iDmWSlGc+laEl+tG+pL+pGe+e dqla+++e+lg+p++kll+++k+ak+f+++k+

Q: 398   MPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPAQKLLDSSKRAKNFVSSKG  457

         ************************************************************

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

         +p+y++ t+ sd +++l+ ++++++k r +p+s+e+g+alk ++d lf d+lk++le+dp

Q: 458   YPRYCTITTLSDGSVILNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDP  517

         ************************************************************

S: 301   akRitpkealkhpfv  315

         a R+tp++al+hp++

Q: 518   AIRMTPSQALRHPWL  532

         **************6

Domain Sequence
(FASTA)

YEVLKVIGKG SFGQVVKAYD HKTHQHVALK MVRNEKRFHR QAAEEIRILE HLRKQDKDNN 60

MNVIHMLENF TFRNHICMTF ELLSMNLYEL IKKNKFQGFS LPLVRKFAHS ILQCLDALHK 120

NRIIHCDLKP ENILLKQQGR SGIKVIDFGS SCYEHQRVYT YIQSRFYRAP EVILGARYGM 180

PIDMWSLGCI LAELLTGYPL LPGEDEGDQL ACMIELLGMP AQKLLDSSKR AKNFVSSKGY 240

PRYCTITTLS DGSVILNGGR SRRGKLRGPP ESREWGNALK GCDDPLFLDF LKQCLEWDPA 300

IRMTPSQALR HPWL 314

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>