EKS-PAT-00204

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00204

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	622.7	1.5E-187	156	512	357

Status

Unreviewed

Ensembl Protein

ENSPTRP00000000500

UniProt Accession

H2PY88;

Protein Name

Protein Synonyms/Alias

PTEN induced putative kinase 1;

Gene Name

ENSG00000158828

Gene Synonyms/Alias

ENSG00000158828; PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000000291	ENSPTRP00000000500	ENSPTRT00000000572

Organism

Pan troglodytes

Functional Description

Protein Length

581

Protein Sequence
(FASTA)

MAVRQALGRG LQLGRALLLR FTGKPGRAYG LGRPGPAAGC VRGERPGWAA GPGAEPRRVG 60

LGLPNRLRFF RQSVAGLAAR LQRQFVVRAW GCAGPCGRAV FLAFGLGLGL IEEKQAESRR 120

AVSACQEIQA IFTQKSKPGP DPLDTRRLQG FRLEEYLIGQ SIGKGCSAAV YEATMPTLPQ 180

NLEVTKSTGL LPGRGPGTSA PGEGQERAPG APAFPLAIKM MWNISAGSSS EAILNTMSQE 240

LVPASRVALA GEYGAVTYRK SKRGPKQLAP HPNIIRVLRA FTSSVPLLPG ALVDYPDVLP 300

SRLHPEGLGH GRTLFLVMKN YPCTLRQYLC VNTPSPRLAA MMLLQLLEGV DHLVQQGIAH 360

RDLKSDNILV ELDPDGCPWL VIADFGCCLA DESIGLQLPF SSWYVDRGGN GCLMAPEVST 420

ARPGPRAVID YSKADAWAVG AIAYEIFGLV NPFYGQGKAH LESRSYREAQ LPALPESVPP 480

DVRQLVRALL QREASKRPSA RVAANVLHLS LWGEHILALK NLKLDKMVGW LLQQSAATLL 540

ASRLTEKCCV ETKMKMLFLA NLECETLCQA ALLLCSWRAA L 581

Nucleotide Sequence
(FASTA)

ATGGCGGTGC GACAGGCGCT GGGCCGCGGC CTGCAGCTGG GTCGAGCGCT GCTGCTGCGC 60

TTCACGGGCA AGCCCGGCCG GGCCTACGGC TTGGGGCGGC CGGGCCCGGC GGCGGGCTGT 120

GTCCGCGGGG AGCGTCCAGG CTGGGCCGCA GGACCGGGCG CGGAGCCTCG CAGGGTCGGG 180

CTCGGGCTCC CTAACCGTCT CCGCTTCTTC CGCCAGTCGG TGGCCGGGCT GGCGGCGCGG 240

CTGCAGCGGC AGTTCGTGGT GCGGGCCTGG GGCTGTGCGG GCCCTTGCGG CCGGGCAGTC 300

TTTCTGGCCT TCGGGCTAGG GCTGGGCCTC ATCGAGGAAA AACAGGCGGA GAGCCGGCGG 360

GCGGTCTCGG CCTGTCAGGA GATCCAGGCA ATTTTTACCC AGAAAAGCAA GCCAGGGCCT 420

GACCCGTTGG ACACGAGACG CTTGCAGGGC TTTCGGCTGG AGGAGTATCT GATAGGGCAG 480

TCCATTGGTA AGGGCTGCAG TGCTGCTGTG TATGAAGCCA CCATGCCTAC ATTGCCCCAG 540

AACCTGGAGG TGACAAAGAG CACCGGGTTG CTTCCAGGGA GAGGCCCAGG TACCAGTGCA 600

CCAGGAGAAG GGCAAGAGCG AGCTCCGGGG GCCCCTGCCT TCCCCTTGGC CATCAAGATG 660

ATGTGGAACA TCTCGGCAGG TTCCTCCAGC GAAGCCATCT TGAACACAAT GAGCCAGGAG 720

CTGGTCCCAG CGAGCCGAGT GGCCTTGGCT GGGGAGTATG GAGCAGTCAC TTACAGAAAA 780

TCCAAGAGAG GTCCCAAGCA ACTAGCCCCT CACCCCAACA TCATCCGGGT TCTCCGCGCC 840

TTCACCTCTT CCGTGCCGCT GCTGCCAGGG GCCCTGGTCG ACTACCCTGA TGTGCTGCCC 900

TCACGCCTCC ACCCTGAAGG CCTGGGCCAT GGCCGGACGC TGTTCCTCGT TATGAAGAAC 960

TATCCCTGTA CCCTGCGCCA GTACCTTTGT GTGAACACAC CCAGCCCCCG CCTCGCTGCC 1020

ATGATGCTGC TGCAGCTGCT GGAAGGCGTG GACCATCTGG TTCAACAGGG CATCGCGCAC 1080

AGAGACCTGA AATCCGACAA CATCCTTGTG GAGCTGGACC CAGACGGCTG CCCCTGGCTG 1140

GTGATCGCAG ATTTTGGCTG CTGCCTGGCT GATGAGAGCA TCGGCCTGCA GTTGCCCTTC 1200

AGCAGCTGGT ACGTGGATCG GGGCGGAAAC GGCTGTCTGA TGGCCCCAGA GGTGTCCACG 1260

GCCCGTCCTG GCCCCAGGGC AGTGATTGAC TACAGCAAGG CTGATGCCTG GGCAGTGGGA 1320

GCCATCGCCT ATGAAATCTT CGGGCTTGTC AATCCCTTCT ACGGCCAGGG CAAGGCCCAC 1380

CTTGAAAGCC GCAGCTACCG AGAGGCTCAG CTACCTGCAC TGCCCGAGTC AGTGCCTCCA 1440

GACGTGAGAC AGTTGGTGAG GGCACTGCTC CAGCGAGAGG CCAGCAAGAG ACCATCTGCC 1500

CGAGTAGCCG CAAATGTGCT TCATCTAAGC CTCTGGGGTG AACATATTCT AGCCCTGAAG 1560

AATCTGAAGT TAGACAAGAT GGTTGGTTGG CTCCTCCAAC AATCGGCCGC CACTTTGTTG 1620

GCCAGCAGGC TCACAGAGAA GTGTTGTGTG GAAACAAAAA TGAAGATGCT CTTTCTGGCT 1680

AACCTGGAGT GTGAAACGCT CTGCCAGGCA GCCCTCCTCC TCTGCTCATG GAGGGCAGCC 1740

CTGTGA 1746

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeidqesavaakkfp  59

         ylig+++gkgc+aavyeat++tl+q+le++k++gll g+++++++++++qe+a++a++fp

Q: 156   YLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLpGRGPGTSAPGEGQERAPGAPAFP  215

         99*********************************99***********************

S: 60    laiklmfnieadssseallksmsqelvpasrvaldgeygav........pkllakhPniv  111

         laik+m+ni+a+sssea+l++msqelvpasrval+geygav        pk+la+hPni+

Q: 216   LAIKMMWNISAGSSSEAILNTMSQELVPASRVALAGEYGAVtyrkskrgPKQLAPHPNII  275

         ************************************************************

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rvlraf++sv+llP+al+dyPd+lp+rl+peglg+g+tl+lvmk+y++tlr+yl+++++s

Q: 276   RVLRAFTSSVPLLPGALVDYPDVLPSRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPS  335

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         +rlaa++l+qlle+vdhlv++g+ahrdlksdnilveld+d++P+lviadfGCclad+++g

Q: 336   PRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIG  395

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp++s++vd+GGn++lmaPe+sta+pGp+avi+y+kad+WavGa+ayeifgl+nPfyg

Q: 396   LQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYG  455

         ************************************************************

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

         +gka+les+sy+eaqlPalpesvpp++rqlv++ll+reaskr+sa++aanvl+lsl+

Q: 456   QGKAHLESRSYREAQLPALPESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLW  512

         ********************************************************9

Domain Sequence
(FASTA)

YLIGQSIGKG CSAAVYEATM PTLPQNLEVT KSTGLLPGRG PGTSAPGEGQ ERAPGAPAFP 60

LAIKMMWNIS AGSSSEAILN TMSQELVPAS RVALAGEYGA VTYRKSKRGP KQLAPHPNII 120

RVLRAFTSSV PLLPGALVDY PDVLPSRLHP EGLGHGRTLF LVMKNYPCTL RQYLCVNTPS 180

PRLAAMMLLQ LLEGVDHLVQ QGIAHRDLKS DNILVELDPD GCPWLVIADF GCCLADESIG 240

LQLPFSSWYV DRGGNGCLMA PEVSTARPGP RAVIDYSKAD AWAVGAIAYE IFGLVNPFYG 300

QGKAHLESRS YREAQLPALP ESVPPDVRQL VRALLQREAS KRPSARVAAN VLHLSLW 357

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>