EKS-PAT-00237

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00237

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	327.5	4.8E-98	53	303	251

Status

Unreviewed

Ensembl Protein

ENSPTRP00000003178

UniProt Accession

H2Q0Z2;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000163545

Gene Synonyms/Alias

ENSG00000163545;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000001897	ENSPTRP00000003178	ENSPTRT00000003453

Organism

Pan troglodytes

Functional Description

Protein Length

627

Protein Sequence
(FASTA)

MESLVFTRPS GPTPSAAELA RPLAEGLIKS PKPLMKKQAV KRHHHKHNLR HRYEFLETLG 60

KGTYGKVKKA RESSGRLVAI KSIRKDKIKD EQDLMHIRRE IEIMSSLNHP HIIAIHEVFE 120

NSSKIVIVME YASRGDLYDY ISERQQLSER EARHFFRQIV SAVHYCHQNR VVHRDLKLEN 180

ILLDANGNIK IADFGLSNLY HQGKFLQTFC GSPLYASPEI VNGKPYTGPE VDSWSLGVLL 240

YILVHGTMPF DGHDHKILVK QISNGAYREP PKPSDACGLI RWLLMVNPTR RATLEDVASH 300

WWVNWGYATR VGEQEAPHEG GHPGSDSVRA SVADWLRRSS RPLLENGAKV CSFFKQHAPG 360

GGSTTPGLER QHSLKKSRKE NDMAQSLHSD TADEFCHRPG KNLKLPKGIL KKKVSASAEG 420

AQEDPPELSP IPASPGQAAP LLPKKGILKK PQQRESGYYS SPEPSESGEL LDAGDVFVSG 480

DPKEQKPPQA SGLLLHRKGI LKLNGKFSQT ALELAAPTTF GSLDELAPSR PLARASRPSG 540

AVSEDSILSS ESFDQLDLPE RLPEPPLRGC VSVDNLMGLE EPPSEGPGSC LRRWRQDPLG 600

DSCFSLTDCQ EVTATYRQAL RVCSKLT 627

Nucleotide Sequence
(FASTA)

ATGGAGTCGC TGGTTTTCAC GCGGCCCTCC GGCCCCACTC CCTCGGCCGC AGAGCTAGCC 60

CGGCCGCTGG CGGAAGGGCT GATCAAGTCG CCCAAGCCCC TAATGAAGAA GCAGGCGGTG 120

AAGCGGCACC ACCACAAGCA CAACCTGCGG CACCGCTACG AGTTCCTGGA GACCCTGGGC 180

AAAGGCACCT ACGGGAAGGT GAAGAAGGCG CGGGAGAGCT CGGGGCGCCT GGTGGCCATC 240

AAGTCAATCC GGAAGGACAA AATCAAAGAT GAGCAAGATC TGATGCACAT ACGGAGGGAG 300

ATTGAGATCA TGTCATCACT CAACCACCCT CACATCATTG CCATCCATGA AGTGTTTGAG 360

AACAGCAGCA AGATCGTGAT CGTCATGGAG TATGCCAGCC GGGGCGACCT TTATGACTAC 420

ATCAGCGAGC GGCAGCAGCT CAGTGAGCGC GAAGCTAGGC ATTTCTTCCG GCAGATCGTC 480

TCTGCCGTGC ACTATTGCCA TCAGAACAGA GTTGTCCACC GAGATCTCAA GCTGGAGAAC 540

ATCCTCTTGG ATGCCAATGG GAATATCAAG ATTGCTGACT TCGGCCTCTC CAACCTCTAC 600

CATCAAGGCA AGTTCCTGCA GACATTCTGT GGGAGCCCCC TCTATGCCTC GCCAGAGATT 660

GTCAATGGAA AGCCCTACAC AGGCCCAGAG GTGGACAGCT GGTCCCTGGG TGTTCTCCTC 720

TACATCCTGG TGCATGGCAC CATGCCCTTT GACGGGCATG ACCATAAGAT CCTAGTGAAA 780

CAGATCAGCA ACGGGGCCTA CCGGGAGCCA CCTAAACCCT CTGATGCCTG TGGCCTGATC 840

CGGTGGCTGT TGATGGTGAA CCCCACCCGC CGGGCCACCC TGGAGGATGT GGCCAGTCAC 900

TGGTGGGTCA ACTGGGGCTA CGCCACCCGA GTGGGAGAGC AGGAGGCTCC GCATGAGGGT 960

GGGCACCCTG GCAGTGACTC TGTCCGCGCC TCCGTGGCTG ACTGGCTCCG GCGTTCCTCC 1020

CGCCCCCTCC TGGAGAATGG GGCCAAGGTG TGCAGCTTCT TCAAGCAGCA TGCACCTGGT 1080

GGGGGAAGCA CCACCCCTGG CCTGGAGCGC CAGCATTCGC TCAAGAAGTC CCGCAAGGAG 1140

AATGACATGG CCCAGTCTCT CCACAGTGAC ACGGCTGATG AATTCTGCCA TCGCCCTGGC 1200

AAGAACCTCA AGCTGCCAAA GGGCATTCTC AAGAAGAAGG TGTCAGCCTC TGCAGAGGGG 1260

GCACAAGAGG ACCCTCCGGA GCTCAGCCCA ATCCCTGCGA GCCCAGGGCA GGCTGCCCCC 1320

CTGCTCCCCA AGAAGGGCAT TCTCAAGAAG CCCCAACAGC GCGAGTCTGG CTACTACTCC 1380

TCTCCCGAGC CCAGTGAATC TGGGGAGCTC TTAGACGCAG GCGACGTGTT TGTGAGTGGG 1440

GATCCCAAGG AGCAGAAGCC TCCGCAAGCT TCAGGGCTGC TCCTCCATCG CAAAGGCATC 1500

CTCAAACTCA ATGGCAAGTT CTCCCAGACA GCCTTGGAGC TCGCGGCCCC CACCACCTTC 1560

GGCTCCTTGG ATGAACTCGC CCCATCTCGC CCCCTGGCCC GGGCCAGCCG ACCCTCAGGG 1620

GCTGTGAGCG AGGACAGCAT CCTGTCCTCT GAGTCCTTTG ACCAGCTGGA CTTGCCTGAA 1680

CGGCTCCCAG AGCCCCCACT GCGGGGCTGT GTGTCTGTGG ACAACCTCAT GGGGCTTGAG 1740

GAGCCCCCCT CAGAGGGCCC TGGAAGCTGC CTGAGGCGCT GGCGGCAGGA TCCTTTGGGG 1800

GACAGCTGCT TTTCCCTGAC AGACTGCCAG GAGGTGACAG CGACCTACCG GCAGGCACTG 1860

AGGGTCTGCT CAAAGCTCAC CTGA 1884

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++l+tlG+g++gkVk+a+++  ++ va+K i+k+k+ +e+ l +i+rEiei+++l+hp+

Q: 53    YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIkDEQDLMHIRREIEIMSSLNHPH  111

         99***************9986.799**********996778899****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         ii ++ev+e+++k+++v+eyas+g+L+dyi+e+++l+e+ear++f+q+vsav+Y+h++++

Q: 112   IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV  171

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlK+eN+lld+++nikiaDFGl+nl+++gk l+tfcGsp Ya+Pe+++gk+Y+gp+v

Q: 172   VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV  231

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D WslGv+Ly+lv g++Pfd+++ k l+++i++g ++ p k s ++  L+r lL+v+p++

Q: 232   DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS-DACGLIRWLLMVNPTR  290

         ****************************************966.5668************

S: 240   Ratieeilkhewl  252

         Rat+e++ +h w+

Q: 291   RATLEDVASHWWV  303

         ************6

Domain Sequence
(FASTA)

YEFLETLGKG TYGKVKKARE SSGRLVAIKS IRKDKIKDEQ DLMHIRREIE IMSSLNHPHI 60

IAIHEVFENS SKIVIVMEYA SRGDLYDYIS ERQQLSEREA RHFFRQIVSA VHYCHQNRVV 120

HRDLKLENIL LDANGNIKIA DFGLSNLYHQ GKFLQTFCGS PLYASPEIVN GKPYTGPEVD 180

SWSLGVLLYI LVHGTMPFDG HDHKILVKQI SNGAYREPPK PSDACGLIRW LLMVNPTRRA 240

TLEDVASHWW V 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013