EKS-PAT-00447

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00447

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	570.0	6.1E-172	2	252	251

Status

Unreviewed

Ensembl Protein

ENSPTRP00000004591

UniProt Accession

H2Q244;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000148660

Gene Synonyms/Alias

ENSG00000148660;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000002643	ENSPTRP00000004591	ENSPTRT00000004973

Organism

Pan troglodytes

Functional Description

Protein Length

536

Protein Sequence
(FASTA)

SRGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI 60

SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI LESVNHIHQH DIVHRDLKPE 120

NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY LSPEVLRKDP YGKPVDIWAC 180

GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR 240

ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL KGAILTTMLV SRNFSAAKSL 300

LNKKSDGGVK PQSNNKNSLV SPAQEPAPLQ TAMEPQTTVV HNATDGIKGS TESCNTTTED 360

EDLKAAPLRT GNGSSVPEGR SSRDRTAPSA GMQPQPSLCS SAMRKQEIIK ITEQLIEAIN 420

NGDFEAYTKI CDPGLTSFEP EALGNLVEGM DFHKFYFENL LSKNSKPIHT TILNPHVHVI 480

GEDAACIAYI RLTQYIDGQG RPRTSQSEET RVWHRRDGKW LNVHYHCSGA PAAPLQ 536

Nucleotide Sequence
(FASTA)

TCCAGGGGTG CTTTCTCTGT GGTCCGCAGG TGTGTGAAGA AAACCTCCAC GCAGGAGTAC 60

GCAGCAAAAA TCATCAATAC CAAGAAGTTG TCTGCCCGGG ATCACCAGAA ACTAGAACGT 120

GAGGCTCGGA TATGTCGACT TCTGAAACAT CCAAACATCG TGCGCCTCCA TGACAGTATT 180

TCTGAAGAAG GGTTTCACTA CCTCGTGTTT GACCTTGTTA CCGGCGGGGA GCTGTTTGAA 240

GACATTGTGG CCAGAGAGTA CTACAGTGAA GCAGATGCCA GCCACTGTAT ACATCAGATT 300

CTGGAGAGTG TTAACCACAT CCACCAGCAT GACATCGTCC ACAGGGACCT GAAGCCTGAG 360

AACCTGCTGC TGGCGAGTAA ATGCAAGGGT GCCGCCGTCA AGCTGGCTGA TTTTGGCCTA 420

GCCATCGAAG TACAGGGAGA GCAGCAGGCT TGGTTTGGTT TTGCTGGCAC CCCAGGTTAC 480

TTGTCCCCTG AGGTCTTGAG GAAAGATCCC TATGGAAAAC CTGTGGATAT CTGGGCCTGC 540

GGGGTCATCC TGTATATCCT CCTGGTGGGC TATCCTCCCT TCTGGGATGA GGATCAGCAC 600

AAGCTGTATC AGCAGATCAA GGCTGGAGCC TATGATTTCC CATCACCAGA ATGGGACACG 660

GTAACTCCTG AAGCCAAGAA CTTGATCAAC CAGATGCTGA CCATAAACCC AGCCAAGCGC 720

ATCACGGCTG ACCAGGCTCT CAAGCACCCG TGGGTCTGTC AACGATCCAC GGTGGCATCC 780

ATGATGCATC GTCAGGAGAC TGTGGAGTGT TTGCGCAAGT TCAATGCCCG GAGAAAACTG 840

AAGGGTGCCA TCCTCACGAC CATGCTTGTC TCCAGGAACT TCTCAGCTGC CAAAAGCCTA 900

TTGAACAAGA AGTCGGATGG CGGTGTCAAG CCACAGAGCA ACAACAAAAA CAGTCTCGTA 960

AGCCCAGCCC AAGAGCCCGC GCCCTTGCAG ACGGCCATGG AGCCACAAAC CACTGTGGTA 1020

CACAACGCTA CAGATGGGAT CAAGGGCTCC ACAGAGAGCT GCAACACCAC CACAGAAGAT 1080

GAGGACCTCA AAGCTGCCCC GCTCCGCACT GGGAATGGCA GCTCGGTGCC TGAAGGACGG 1140

AGCTCCCGGG ACAGAACAGC CCCCTCTGCA GGCATGCAGC CCCAGCCTTC TCTCTGCTCC 1200

TCAGCCATGC GAAAACAGGA GATCATTAAG ATTACAGAAC AGCTGATTGA AGCCATCAAC 1260

AATGGGGACT TTGAGGCGTA CACGAAGATT TGTGATCCAG GCCTCACTTC CTTTGAGCCT 1320

GAGGCCCTTG GTAACCTCGT GGAGGGGATG GATTTCCATA AGTTTTACTT TGAGAATCTC 1380

CTGTCCAAGA ACAGCAAGCC TATCCATACC ACCATCCTAA ACCCACACGT CCACGTGATT 1440

GGGGAGGACG CAGCGTGCAT CGCCTACATC CGCCTCACCC AGTACATCGA CGGGCAGGGT 1500

CGGCCTCGCA CCAGCCAGTC AGAAGAGACC CGGGTCTGGC ACCGTCGGGA TGGCAAGTGG 1560

CTCAATGTCC ACTATCACTG CTCAGGGGCC CCTGCCGCAC CGCTGCAGTG A 1611

Domain Profile

S: 9     kgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpnivrlhdsis  68

         +gafsvvrrcvk+t++qeyaakiintkklsardhqklerearicrllkhpnivrlhdsis

Q: 2     RGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIS  61

         79**********************************************************

S: 69    eegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvvhrdlkpen  128

         eegfhylvfdlvtggelfedivareyyseadashci+qilesv+hihq+++vhrdlkpen

Q: 62    EEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPEN  121

         ************************************************************

S: 129   lllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygkpvdlwacg  188

         lllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygkpvd+wacg

Q: 122   LLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACG  181

         ************************************************************

S: 189   vilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkmltinpakri  248

         vilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+mltinpakri

Q: 182   VILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI  241

         ************************************************************

S: 249   tadealkhpwi  259

         tad+alkhpw+

Q: 242   TADQALKHPWV  252

         **********8

Domain Sequence
(FASTA)

RGAFSVVRRC VKKTSTQEYA AKIINTKKLS ARDHQKLERE ARICRLLKHP NIVRLHDSIS 60

EEGFHYLVFD LVTGGELFED IVAREYYSEA DASHCIHQIL ESVNHIHQHD IVHRDLKPEN 120

LLLASKCKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDIWACG 180

VILYILLVGY PPFWDEDQHK LYQQIKAGAY DFPSPEWDTV TPEAKNLINQ MLTINPAKRI 240

TADQALKHPW V 251

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013