EPS-PAT-00005

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PAT-00005

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	163.7	2.4E-48	174	320	147

Status

Unreviewed

Ensembl Protein

ENSPTRP00000039811

UniProt Accession

H2QZY8;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000079393

Gene Synonyms/Alias

ENSG00000079393;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000002655	ENSPTRP00000039811	ENSPTRT00000047891

Organism

Pan troglodytes

Functional Description

Protein Length

327

Protein Sequence
(FASTA)

MGLPQPRLPA PALQAGPATA GCRPELRGQS WSLLPATGLC HFATLALILL VLLEALAQAD 60

TQKMVEAQRG VGPRACYSIW LLLAPTPPLS HCLQSPQKQH QVCGDRRLKA GSTNCPSEKC 120

TAWARYSHRM DSLQKQDLRR PKIHGAVRAS PYQPPTLASL QRLLWVHQAA TLNHIDEVWP 180

SLFLGDAYAA RDKSKMIQLG ITHVVNAAAG KFQVDTGAKF YRGMSLEYYG IEADDNPFFD 240

LSVYFLPVAR YIRAALSVPQ GRVLVHCAMG VSRSATLVLA FLMIYENMTL VEAIQTVQAH 300

RNICPNSGFL RQLQVLDNRL GRETGRF 327

Nucleotide Sequence
(FASTA)

ATGGGTCTTC CCCAACCGAG GCTTCCTGCA CCAGCTCTGC AGGCTGGACC AGCAACTGCG 60

GGGTGCCGGC CAGAGCTGAG GGGCCAGAGC TGGTCCTTAC TCCCTGCCAC GGGGCTCTGC 120

CACTTTGCCA CCCTGGCACT GATCCTGCTG GTGCTGCTGG AGGCTCTGGC CCAGGCGGAC 180

ACACAGAAGA TGGTGGAAGC CCAGCGTGGG GTCGGCCCTA GAGCCTGCTA CTCCATCTGG 240

CTCCTCCTGG CGCCTACACC CCCTCTCAGC CACTGTCTTC AGTCTCCACA GAAACAGCAT 300

CAAGTGTGCG GAGACAGGCG GCTGAAAGCC GGCAGCACAA ACTGCCCGTC AGAGAAGTGC 360

ACAGCCTGGG CCAGATACTC CCACAGGATG GACTCACTGC AGAAGCAGGA CCTCCGGAGG 420

CCCAAGATCC ACGGGGCAGT CCGGGCATCT CCCTACCAGC CGCCCACATT GGCTTCGCTG 480

CAGCGCTTGC TGTGGGTCCA TCAGGCTGCC ACACTGAACC ATATCGATGA GGTCTGGCCC 540

AGCCTCTTCC TGGGAGATGC GTACGCAGCC CGGGACAAGA GCAAGATGAT CCAGCTGGGA 600

ATCACCCACG TTGTGAATGC CGCTGCGGGC AAGTTCCAGG TGGACACAGG TGCCAAATTC 660

TACCGTGGAA TGTCCCTGGA GTACTATGGC ATCGAGGCAG ATGACAACCC CTTCTTCGAC 720

CTCAGTGTCT ACTTTCTGCC TGTTGCTCGA TACATCCGAG CTGCCCTCAG TGTTCCCCAA 780

GGCCGCGTGC TGGTACACTG TGCCATGGGG GTAAGCCGCT CTGCCACACT TGTCCTGGCC 840

TTCCTCATGA TCTATGAGAA CATGACGCTG GTAGAGGCCA TCCAGACGGT GCAGGCCCAC 900

CGCAATATCT GCCCTAACTC AGGCTTCCTC CGGCAGCTCC AGGTTCTGGA CAACCGACTG 960

GGGCGGGAGA CGGGGCGGTT CTGA 984

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         +++e++p+l+lgd+  a d+ ++ +lgit+v+na+++ ++v+++ ++++ ++ +y +i++

Q: 174   HIDEVWPSLFLGDAYAARDKSKMIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA  233

         699*********************************************************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD++ +dl+ yf ++a++i  a + ++g+vlvHCa+GvsRSatlvla+Lm++e+++l++A

Q: 234   DDNPFFDLSVYFLPVARYIRAAlSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEA  293

         *********************9999***********************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         i++v+++r +i+pn+gfl+QL  l+++l

Q: 294   IQTVQAHR-NICPNSGFLRQLQVLDNRL  320

         ********.****************987

Domain Sequence
(FASTA)

HIDEVWPSLF LGDAYAARDK SKMIQLGITH VVNAAAGKFQ VDTGAKFYRG MSLEYYGIEA 60

DDNPFFDLSV YFLPVARYIR AALSVPQGRV LVHCAMGVSR SATLVLAFLM IYENMTLVEA 120

IQTVQAHRNI CPNSGFLRQL QVLDNRL 147

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013