EKS-PAT-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/YANK	509.7	1.6E-153	93	352	260

Status

Unreviewed

Ensembl Protein

ENSPTRP00000005404

UniProt Accession

H2Q2T0;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000165752

Gene Synonyms/Alias

ENSG00000165752;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000003074	ENSPTRP00000005404	ENSPTRT00000005842

Organism

Pan troglodytes

Functional Description

Protein Length

486

Protein Sequence
(FASTA)

MRSGAERRGS SAAASPGSPP PGRARPAGSD APSALPPPAA GQPRARDSGD VRAQPRPLFQ 60

WSKWKKRMGS SMSAATARRP VFDDKEDVNF DHFQILRAIG KGSFGKVCIV QKRDTEKMYA 120

MKYMNKQQCI ERDEVRNVFR ELEILQEIEH VFLVNLWYSF QDEEDMFMVV DLLLGGDLRY 180

HLQQNVQFSE DTVRLYICEM ALALDYLRGQ HIIHRDVKPD NILLDERGHA HLTDFNIATI 240

IKDGERATAL AGTKPYMAPE IFHSFVNGGT GYSFEVDWWS VGVMAYELLR GWRPYDIHSS 300

NAVESLVQLF STVSVQYVPT WSKEMVALLR KLLTVNPEHR LSSLQDVQAA PALAGVLWDH 360

LSEKRVEPGF VPNKGRLHCD PTFELEEMIL ESRPLHKKKK RLAKNKSRDN SRDSSQSEND 420

YLQDCLDAIQ QDFVIFNREK LKRSQDFPSE PLPAPESRDA AEPVEDEAER SALPMCGPIC 480

PSAGSG 486

Nucleotide Sequence
(FASTA)

ATGAGGAGTG GCGCCGAGCG CAGGGGCAGC AGCGCCGCGG CGTCCCCGGG CTCGCCGCCC 60

CCCGGCCGCG CGCGCCCCGC CGGCTCCGAC GCGCCCTCGG CCCTGCCGCC GCCCGCTGCT 120

GGCCAGCCCC GGGCCCGGGA CTCGGGCGAT GTCCGCGCGC AGCCGCGCCC CCTGTTTCAG 180

TGGAGCAAGT GGAAGAAGAG GATGGGCTCG TCCATGTCGG CGGCCACGGC GCGGAGGCCG 240

GTGTTTGACG ACAAGGAGGA CGTGAACTTC GACCACTTCC AGATCCTTCG GGCCATTGGG 300

AAGGGCAGCT TTGGCAAGGT GTGCATTGTG CAGAAGCGGG ACACGGAGAA GATGTACGCC 360

ATGAAGTACA TGAACAAGCA GCAGTGCATC GAGCGCGACG AGGTCCGCAA CGTCTTCCGG 420

GAGCTGGAGA TCCTGCAGGA GATCGAGCAC GTCTTCCTGG TGAACCTCTG GTACTCCTTC 480

CAGGACGAGG AGGACATGTT TATGGTCGTG GACCTGCTTC TGGGCGGGGA CCTGCGCTAC 540

CACCTGCAGC AGAACGTGCA GTTCTCCGAG GACACGGTGA GGCTGTACAT CTGCGAGATG 600

GCGCTGGCTC TCGACTACCT GCGCGGCCAG CACATCATCC ACAGAGATGT CAAGCCTGAC 660

AACATTCTCC TGGATGAGAG AGGACATGCA CACCTGACCG ACTTCAACAT TGCCACCATC 720

ATCAAGGACG GGGAGCGGGC GACGGCATTA GCAGGCACCA AGCCGTACAT GGCTCCGGAG 780

ATCTTCCACT CTTTTGTCAA CGGCGGGACC GGCTACTCCT TCGAGGTGGA CTGGTGGTCG 840

GTGGGGGTGA TGGCCTATGA GCTGCTGCGA GGATGGAGGC CCTATGACAT CCACTCCAGC 900

AACGCCGTGG AGTCCCTGGT GCAGCTGTTC AGCACCGTGA GCGTCCAGTA TGTCCCCACG 960

TGGTCCAAGG AGATGGTGGC CTTGCTGCGG AAGCTCCTCA CTGTGAACCC CGAGCACCGG 1020

CTCTCCAGCC TCCAGGACGT GCAGGCAGCC CCGGCGCTGG CCGGCGTGCT GTGGGACCAC 1080

CTGAGCGAGA AGAGGGTGGA GCCGGGCTTC GTGCCCAACA AAGGCCGTCT GCACTGCGAC 1140

CCCACCTTTG AGCTGGAGGA GATGATTCTG GAGTCCAGGC CCCTGCACAA GAAGAAGAAG 1200

CGCCTGGCCA AGAACAAGTC CCGGGACAAC AGCAGGGACA GCTCCCAGTC CGAGAATGAC 1260

TATCTTCAAG ACTGCCTCGA TGCCATCCAG CAAGACTTCG TGATTTTTAA CAGAGAAAAG 1320

CTGAAGAGGA GCCAGGACTT CCCGAGCGAG CCTCTCCCCG CCCCTGAGTC CAGGGATGCT 1380

GCGGAGCCTG TGGAGGACGA GGCGGAACGC TCCGCCCTGC CCATGTGCGG CCCCATTTGC 1440

CCCTCGGCCG GGAGCGGCTA G 1461

Domain Profile

S: 1     fqilraiGkGsfGkvcivqkrdtkklyalkymnkqkcierdevrnvlrelellqelehpf  60

         fqilraiGkGsfGkvcivqkrdt+k+ya+kymnkq+cierdevrnv+rele+lqe+eh+f

Q: 93    FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVF  152

         9***********************************************************

S: 61    lvnlwysfqdeedlfmvvdlllGGdlryhlqqnvkfsedtvklyicelalaleylqeqki  120

         lvnlwysfqdeed+fmvvdlllGGdlryhlqqnv+fsedtv+lyice+alal+yl+ q+i

Q: 153   LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHI  212

         ************************************************************

S: 121   ihrdikpdnilldekGhahltdfniatvlkdeeratslaGtkpymapevfasylekeaGy  180

         ihrd+kpdnillde+Ghahltdfniat++kd erat+laGtkpymape+f+s+++ ++Gy

Q: 213   IHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGY  272

         ************************************************************

S: 181   sfevdwwslGvvayellrgrrpyeiksstaveeivnlfktesvkypstwskelvallkkl  240

         sfevdwws+Gv+ayellrg+rpy+i+ss+ave++v+lf+t+sv+y++twske+vall+kl

Q: 273   SFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKL  332

         ************************************************************

S: 241   levdpekrlssledikkapy  260

         l+v+pe+rlssl+d+++ap+

Q: 333   LTVNPEHRLSSLQDVQAAPA  352

         ****************9986

Domain Sequence
(FASTA)

FQILRAIGKG SFGKVCIVQK RDTEKMYAMK YMNKQQCIER DEVRNVFREL EILQEIEHVF 60

LVNLWYSFQD EEDMFMVVDL LLGGDLRYHL QQNVQFSEDT VRLYICEMAL ALDYLRGQHI 120

IHRDVKPDNI LLDERGHAHL TDFNIATIIK DGERATALAG TKPYMAPEIF HSFVNGGTGY 180

SFEVDWWSVG VMAYELLRGW RPYDIHSSNA VESLVQLFST VSVQYVPTWS KEMVALLRKL 240

LTVNPEHRLS SLQDVQAAPA 260

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:450835

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013