EKS-PAT-00271

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00271

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	333.2	1.3E-99	204	505	302

Status

Unreviewed

Ensembl Protein

ENSPTRP00000008537

UniProt Accession

H2Q624;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000135409

Gene Synonyms/Alias

ENSG00000135409;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000005015	ENSPTRP00000008537	ENSPTRT00000009234
ENSPTRG00000005015	ENSPTRP00000050289	ENSPTRT00000057419

Organism

Pan troglodytes

Functional Description

Protein Length

573

Protein Sequence
(FASTA)

MLGSLGLWAL LPTAVEAPPN RRTCVFFEAP GVRGSTKTLG ELLDTGTELP RAIRCLYSRC 60

CFGIWNLTQD RAQVEMQGCR DSDEPGCESL HCDPSPRAHP SPGSTLFTCS CGTDFCNANY 120

SHLPPPGSPG TPGSQGPQAA PGESIWMALV LLGLFLLLLL LLGSIILALL QRKNYRVRGE 180

PVPEPRPDSG RDWSVELQEL PELCFSQVIR EGGHAVVWAG QLQGKLVAIK AFPPRSVAQF 240

QAERALYEIP GLQHDHIVRF ITASRGGPGR LLSGPLLVLE LHPKGSLCHY LTQYTSDWGS 300

SLRMALSLAQ GLAFLHEERW QNGQYKPGIA HRDLSSQNVL IREDGSCAIG DLGLALVLPG 360

LTQPPAWTPT QPQGPAAIME AGTQRYMAPE LLDKTLDLQD WGMALRRADI YSLALLLWEI 420

LSRCPDLRPD SSPPPFQLAY EAELGNTPTS DELWALAVQE RRRPYIPSTW RCFATDPDGL 480

RELLEDCWDA DPEARLTAEC VQQRLAALAH PQESHPFPES CPRGCPPLCP EDCTSIPAPT 540

ILPCRPQRSA CHFSVQQGPC SRNPQPACTL SSV 573

Nucleotide Sequence
(FASTA)

ATGCTAGGGT CTTTGGGGCT TTGGGCATTA CTTCCCACAG CTGTGGAAGC ACCCCCAAAC 60

AGGCGAACCT GTGTGTTCTT TGAGGCCCCT GGAGTGCGGG GAAGCACAAA GACACTGGGA 120

GAGCTGCTAG ATACAGGCAC AGAGCTCCCC AGAGCTATCC GCTGCCTCTA CAGCCGCTGC 180

TGCTTTGGGA TCTGGAACCT GACCCAAGAC CGGGCACAGG TGGAAATGCA AGGATGCCGA 240

GACAGTGATG AGCCAGGCTG TGAGTCCCTC CACTGTGACC CAAGTCCCCG AGCCCACCCC 300

AGCCCTGGCT CCACTCTCTT CACCTGCTCC TGTGGCACTG ACTTCTGCAA TGCCAATTAC 360

AGCCATCTGC CTCCTCCAGG GAGCCCTGGG ACTCCTGGCT CCCAGGGTCC CCAGGCTGCC 420

CCAGGTGAGT CCATCTGGAT GGCACTGGTG CTGCTGGGGC TGTTCCTCCT CCTCCTGCTG 480

CTGCTGGGCA GCATCATCTT GGCCCTGCTA CAGCGAAAGA ACTACAGAGT GCGAGGTGAG 540

CCAGTGCCAG AGCCAAGGCC AGACTCAGGC AGGGACTGGA GTGTGGAGCT GCAGGAGCTG 600

CCTGAGCTGT GTTTCTCCCA GGTAATCCGG GAAGGAGGTC ATGCAGTGGT TTGGGCCGGG 660

CAGCTGCAAG GAAAACTGGT TGCCATCAAG GCCTTCCCAC CGAGGTCTGT GGCTCAGTTC 720

CAAGCTGAGA GAGCATTGTA CGAAATTCCA GGCCTACAGC ACGACCACAT TGTCCGATTT 780

ATCACTGCCA GCCGGGGGGG CCCTGGCCGC CTGCTCTCTG GGCCCCTGCT GGTACTAGAA 840

CTGCATCCCA AGGGCTCCCT GTGCCACTAC TTGACCCAGT ACACCAGTGA CTGGGGAAGT 900

TCCCTGCGGA TGGCACTGTC CCTGGCCCAG GGCCTGGCAT TTCTCCATGA GGAGCGCTGG 960

CAGAATGGCC AATATAAACC AGGTATTGCC CACCGAGATC TGAGCAGCCA GAATGTGCTC 1020

ATTCGGGAAG ATGGATCGTG TGCCATTGGA GACCTGGGCC TTGCCTTGGT GCTCCCTGGC 1080

CTCACTCAGC CCCCTGCCTG GACCCCTACT CAACCACAAG GCCCAGCTGC CATCATGGAA 1140

GCTGGCACCC AGAGGTACAT GGCACCAGAG CTCTTGGACA AGACTCTGGA CCTACAGGAT 1200

TGGGGCATGG CCCTCCGACG AGCTGATATT TACTCTTTGG CTTTGCTCCT GTGGGAGATA 1260

CTGAGTCGCT GCCCAGATTT GAGGCCTGAC AGCAGTCCAC CACCCTTCCA ACTGGCCTAT 1320

GAGGCAGAAC TGGGCAATAC CCCTACCTCT GATGAGCTAT GGGCCTTGGC AGTGCAGGAG 1380

AGGAGGCGTC CCTACATCCC ATCCACCTGG CGCTGCTTTG CCACAGACCC TGATGGGCTG 1440

AGGGAGCTCC TAGAAGACTG TTGGGATGCA GACCCAGAAG CACGGCTGAC AGCTGAGTGT 1500

GTACAGCAGC GCCTGGCTGC CTTGGCCCAT CCTCAAGAGA GCCACCCCTT TCCAGAGAGC 1560

TGTCCACGTG GCTGCCCACC TCTCTGCCCA GAAGACTGTA CTTCAATTCC TGCCCCTACC 1620

ATCCTCCCCT GTAGGCCTCA GCGGAGTGCC TGCCACTTCA GCGTTCAGCA AGGCCCTTGT 1680

TCCAGGAATC CTCAGCCTGC CTGTACCCTT TCTTCTGTGT AA 1722

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++++i++G ++ Vw+++l+g+ vA+K+f+ ++ a++++E+++y+ + l+h++i++fi+a

Q: 204   CFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYEIPGLQHDHIVRFITA  263

         57899*******************************************************

S: 62    dk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

          +    ++l+  llv+e+h+kgsL++yL+++t+d+ ++lr+alsla+Gla+LHee ++++

Q: 264   SRgGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEE-RWQN  322

         **889999***********************************************.8999

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee........ldlaansqvG  172

         g++Kp iaHRDl+s+N+l+++d++c+i+DlGLal l   ++         +  aa++++G

Q: 323   GQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPpawtptqpQGPAAIMEAG  382

         **********************************87776666688888888899******

S: 173   tkRYmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfee  229

         t+RYmaPE+l+++l+l+d+  a++raD+Ysl+L+lWE++sRc +  +d++ ++++l++e+

Q: 383   TQRYMAPELLDKTLDLQDWGmALRRADIYSLALLLWEILSRCPDlrPDSSPPPFQLAYEA  442

         *******************99***********************999*************

S: 230   vvgsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvk  288

         ++g++P+ +e++++ v+++ rP ip++w++ + + + l++lle+cWdadpeaRlta++v+

Q: 443   ELGNTPTSDELWALAVQERRRPYIPSTWRCFAtDPDGLRELLEDCWDADPEARLTAECVQ  502

         ******************************98789*************************

S: 289   krl  291

+rl

Q: 503   QRL  505

Domain Sequence
(FASTA)

CFSQVIREGG HAVVWAGQLQ GKLVAIKAFP PRSVAQFQAE RALYEIPGLQ HDHIVRFITA 60

SRGGPGRLLS GPLLVLELHP KGSLCHYLTQ YTSDWGSSLR MALSLAQGLA FLHEERWQNG 120

QYKPGIAHRD LSSQNVLIRE DGSCAIGDLG LALVLPGLTQ PPAWTPTQPQ GPAAIMEAGT 180

QRYMAPELLD KTLDLQDWGM ALRRADIYSL ALLLWEILSR CPDLRPDSSP PPFQLAYEAE 240

LGNTPTSDEL WALAVQERRR PYIPSTWRCF ATDPDGLREL LEDCWDADPE ARLTAECVQQ 300

RL 302

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

ptr:467005

;

InterPros

IPR000472	; Activin_rcpt.
IPR015771	; Anti-muellerian_hrmn_rcpt_II.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013