EKS-PAT-00250

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00250

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	472.2	8.3E-142	221	534	314

Status

Unreviewed

Ensembl Protein

ENSPTRP00000008820

UniProt Accession

H2Q6F2;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000127334

Gene Synonyms/Alias

ENSG00000127334;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000005191	ENSPTRP00000008820	ENSPTRT00000009535

Organism

Pan troglodytes

Functional Description

Protein Length

600

Protein Sequence
(FASTA)

MLTRKPSAAA PAAYPTGRGG DSAVRQLASP GLGAGATRSG VGTGPPSPIA LPPLRASNAA 60

AAAHTIGGSK HTMNDHLHVG SHAHGQIQVQ QLFEDNSNKR TVLTTQPNGL TTVGKTGLPV 120

VPERQLDSIH RRQGSSTSLK SMEGMGKVKA TPMTPEQAMK QYMQKLTAFE HHEIFSYPEI 180

YFLGLNAKKR QGMTGGPNNG GYDDDQGSYV QVPHDHVAYR YEVLKVIGKG SFGQVVKAYD 240

HKVHQHVALK MVRNEKRFHR QAAEEIRILE HLRKQDKDNT MNVIHMLENF TFRNHICMTF 300

ELLSMNLYEL IKKNKFQGFS LPLVRKFAHS ILQCLDALHK NRIIHCDLKP ENILLKQQGR 360

SGIKVIDFGS SCYEHQRVYT YIQSRFYRAP EVILGARYGM PIDMWSLGCI LAELLTGYPL 420

LPGEDEGDQL ACMIELLGMP SQKLLDASKR AKNFVSSKGY PRYCTVTTLS DGSVVLNGGR 480

SRRGKLRGPP ESREWGNALK GCDDPLFLDF LKQCLEWDPA VRMTPGQALR HPWLRRRLPK 540

PPTGEKTSVK RITESTGAIT SISKLPPPSS SASKLRTNLA QMTDANGNIQ QRTVLPKLVS 600

Nucleotide Sequence
(FASTA)

ATGTTAACCA GGAAACCTTC GGCCGCCGCT CCCGCCGCCT ACCCGACCGG CCGAGGTGGG 60

GACAGCGCCG TTCGTCAGCT TGCTTCCCCG GGGCTCGGTG CAGGGGCTAC CCGGAGCGGA 120

GTGGGGACTG GCCCGCCCTC CCCCATCGCC CTGCCGCCTC TCCGGGCCAG CAACGCTGCC 180

GCCGCAGCCC ACACGATTGG CGGCAGTAAG CACACAATGA ATGATCACCT GCATGTCGGC 240

AGCCACGCTC ACGGACAGAT CCAGGTTCAA CAGTTGTTTG AGGATAATAG TAACAAGCGG 300

ACAGTGCTCA CGACACAACC AAATGGGCTT ACAACAGTGG GCAAAACGGG CTTGCCAGTG 360

GTGCCAGAGC GGCAGCTGGA CAGCATTCAT AGACGGCAGG GGAGCTCCAC CTCTCTAAAG 420

TCCATGGAAG GCATGGGGAA GGTGAAAGCC ACCCCCATGA CACCTGAACA AGCAATGAAG 480

CAATACATGC AAAAACTCAC AGCCTTCGAA CACCATGAGA TTTTCAGCTA CCCTGAAATA 540

TATTTCTTGG GTCTAAATGC TAAGAAGCGC CAGGGCATGA CAGGTGGGCC CAACAATGGT 600

GGCTATGATG ATGACCAGGG ATCATATGTG CAGGTGCCCC ACGATCACGT GGCTTACAGG 660

TATGAGGTCC TCAAGGTCAT TGGGAAGGGG AGCTTTGGGC AGGTGGTCAA GGCCTACGAT 720

CACAAAGTCC ACCAGCACGT GGCCCTAAAG ATGGTGCGGA ATGAGAAGCG CTTCCACCGG 780

CAAGCAGCGG AGGAGATCCG AATCCTGGAA CACCTGCGGA AGCAGGACAA GGATAACACA 840

ATGAATGTCA TCCATATGCT GGAGAATTTC ACTTTCCGCA ACCACATCTG CATGACGTTT 900

GAGCTGCTGA GCATGAACCT CTATGAGCTC ATCAAGAAGA ATAAATTCCA GGGCTTCAGT 960

CTGCCTTTGG TTCGCAAGTT TGCCCACTCG ATTCTGCAGT GCTTGGATGC TTTGCACAAA 1020

AACAGAATAA TTCACTGTGA CCTTAAGCCC GAGAACATTT TGTTAAAGCA GCAGGGTAGA 1080

AGCGGTATTA AAGTAATTGA TTTTGGCTCC AGTTGTTACG AGCATCAGCG TGTCTACACG 1140

TACATCCAGT CGCGTTTTTA CCGGGCTCCA GAAGTGATCC TTGGGGCCAG GTATGGCATG 1200

CCCATTGATA TGTGGAGCCT GGGCTGCATT TTAGCAGAGC TCCTGACGGG TTACCCCCTC 1260

TTGCCTGGGG AAGATGAAGG GGACCAGCTG GCCTGTATGA TTGAACTGTT GGGCATGCCC 1320

TCACAGAAAC TGCTGGATGC ATCCAAACGA GCCAAAAATT TTGTGAGCTC CAAGGGTTAT 1380

CCCCGTTACT GCACTGTCAC GACTCTCTCA GATGGCTCTG TGGTCCTCAA CGGAGGCCGT 1440

TCCCGGAGGG GGAAACTGAG GGGCCCACCG GAGAGCAGAG AGTGGGGGAA TGCGCTGAAG 1500

GGGTGTGATG ATCCCCTTTT CCTTGACTTC TTAAAACAGT GTTTAGAGTG GGATCCTGCA 1560

GTGCGCATGA CCCCAGGCCA GGCTTTGCGG CACCCCTGGC TGAGGAGGCG GTTGCCAAAG 1620

CCTCCCACCG GGGAGAAAAC GTCAGTGAAA AGGATAACTG AGAGCACCGG TGCTATCACA 1680

TCTATATCCA AGTTACCTCC ACCTTCCAGC TCAGCTTCCA AACTGAGGAC TAATTTGGCG 1740

CAGATGACAG ATGCCAATGG GAATATTCAG CAGAGGACAG TGTTGCCAAA ACTTGTTAGC 1800

TGA 1803

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevl+vigkGsfgqVvka+d+k +++va+k+++n+krf+rqa+eE++iLe+l+k+dk+++

Q: 221   YEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNT  280

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         +nv+++le f+frnh+c++fells+nLyel+kknkf+g+sl lvrk+a++il++L++L++

Q: 281   MNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHK  340

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglkyd  180

         ++iiH+DlKPeNill++++rs +kviDFGss++++q+ +ytyiqsrfYraPE+ilg++y

Q: 341   NRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQR-VYTYIQSRFYRAPEVILGARYG  399

         *************************************.**********************

S: 181   eaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftkke  240

         + iDmWSlGc+laEl+tG+pL+pGe+e dqla+++e+lg+p++kll+++k+ak+f+++k+

Q: 400   MPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKG  459

         ************************************************************

S: 241   apkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedklfkdllkrmleldp  300

         +p+y+++t+ sd +++l+ ++++++k r +p+s+e+g+alk ++d lf d+lk++le+dp

Q: 460   YPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDP  519

         ************************************************************

S: 301   akRitpkealkhpfv  315

         a R+tp +al+hp++

Q: 520   AVRMTPGQALRHPWL  534

         **************6

Domain Sequence
(FASTA)

YEVLKVIGKG SFGQVVKAYD HKVHQHVALK MVRNEKRFHR QAAEEIRILE HLRKQDKDNT 60

MNVIHMLENF TFRNHICMTF ELLSMNLYEL IKKNKFQGFS LPLVRKFAHS ILQCLDALHK 120

NRIIHCDLKP ENILLKQQGR SGIKVIDFGS SCYEHQRVYT YIQSRFYRAP EVILGARYGM 180

PIDMWSLGCI LAELLTGYPL LPGEDEGDQL ACMIELLGMP SQKLLDASKR AKNFVSSKGY 240

PRYCTVTTLS DGSVVLNGGR SRRGKLRGPP ESREWGNALK GCDDPLFLDF LKQCLEWDPA 300

VRMTPGQALR HPWL 314

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013