EKS-PAT-00464

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00464

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RIPK	343.3	9.1E-103	21	283	263

Status

Unreviewed

Ensembl Protein

ENSPTRP00000010556

UniProt Accession

H2Q833;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000129465

Gene Synonyms/Alias

ENSG00000129465;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000006217	ENSPTRP00000010556	ENSPTRT00000011409

Organism

Pan troglodytes

Functional Description

Protein Length

518

Protein Sequence
(FASTA)

MSCVKLWPSG APAPLVSIEE LENQELVGKG GFGTVFRAQH RKWGYDVAVK IVNSKAISRE 60

VKAMASLDNE FVLRLEGVIE KVNWDQDPKP ALVTKFMENG SLSGLLQSQC PRPWPLLCRL 120

LKEVVLGMFY LHDRNPVLLH RDLKPSNVLL DPELHVKLAD FGLSTFQGGS QSGTGSGEPG 180

GTLGYLAPEL FVNVNRKAST ASDVYSFGIL MWAVLAGREV ELPTEPSLVY EAVGNRQNRP 240

SLAELPQAGP ETPGLEGLKE LMQLCWSSKP KDRPSFQECL PKTDEAFQMV ENNMNAAVST 300

VKNFLSQLRG SNRRFSIPES GQGGTEMDGF RRTIENQHSR NDVMVSEWLN KLNLEEPPSS 360

VPKKCPSLTK RSRAQEEQVP QAWTAGTSSD SMAQPPQTPE TSTFRNQMPS PTSTGKPSPG 420

PRGNQGAERQ GMNWSCRTPE PNPVTGRPLV NIYNCSGVQV GDNNYLTMQQ TTALPTWGLA 480

PSGKGRGLQH PPPVGSQEGP KDPEAWSRPQ GWYNHSGK 518

Nucleotide Sequence
(FASTA)

ATGTCGTGCG TCAAGTTATG GCCCAGCGGT GCCCCCGCCC CCTTGGTGTC CATCGAGGAA 60

CTGGAGAACC AGGAGCTCGT CGGCAAAGGC GGGTTCGGCA CAGTGTTCCG GGCGCAACAT 120

AGGAAGTGGG GCTACGATGT GGCGGTCAAG ATCGTAAACT CGAAGGCGAT ATCCAGGGAG 180

GTCAAGGCCA TGGCAAGTCT GGATAACGAA TTCGTGCTGC GCCTAGAAGG GGTTATCGAG 240

AAGGTGAACT GGGACCAAGA TCCCAAGCCG GCTCTGGTGA CTAAATTCAT GGAGAACGGC 300

TCCCTGTCGG GGCTGCTGCA GTCCCAGTGC CCTCGGCCCT GGCCGCTCCT TTGCCGCCTG 360

CTGAAAGAAG TGGTGCTTGG GATGTTTTAC CTGCACGACC GGAACCCGGT GCTCCTGCAC 420

CGGGACCTCA AGCCATCCAA CGTCCTGCTG GACCCAGAGC TGCACGTCAA GCTGGCAGAT 480

TTTGGCCTGT CCACATTTCA GGGAGGCTCA CAGTCAGGGA CAGGGTCCGG GGAGCCAGGG 540

GGCACCCTGG GCTACTTGGC CCCAGAACTG TTTGTTAATG TAAACCGGAA GGCCTCCACA 600

GCCAGTGATG TCTACAGCTT CGGGATCCTA ATGTGGGCAG TGCTTGCTGG AAGAGAAGTT 660

GAGTTGCCAA CCGAACCATC ACTCGTGTAT GAAGCAGTGG GCAACAGGCA GAACCGGCCC 720

TCATTGGCTG AGCTGCCCCA AGCCGGGCCT GAGACTCCCG GCTTAGAAGG ACTGAAGGAG 780

CTAATGCAGC TCTGCTGGAG CAGTAAGCCC AAGGACAGAC CCTCCTTCCA GGAATGCCTA 840

CCAAAAACTG ATGAAGCCTT CCAGATGGTG GAGAACAATA TGAATGCTGC TGTCTCCACG 900

GTAAAGAATT TCCTGTCTCA GCTCAGGGGC AGCAATAGGA GATTTTCTAT CCCAGAGTCA 960

GGCCAAGGAG GGACAGAAAT GGATGGCTTT AGGAGAACCA TAGAAAACCA GCATTCTCGT 1020

AATGATGTCA TGGTTTCTGA GTGGCTAAAC AAACTGAATC TAGAGGAGCC TCCCAGCTCT 1080

GTTCCTAAAA AATGCCCGAG CCTTACCAAG AGGAGCAGGG CACAAGAGGA GCAGGTTCCA 1140

CAAGCCTGGA CAGCAGGCAC ATCTTCAGAT TCAATGGCCC AACCTCCCCA GACTCCAGAG 1200

ACCTCAACTT TCAGAAACCA GATGCCCAGC CCCACCTCAA CTGGAAAACC AAGTCCTGGA 1260

CCCCGAGGGA ATCAGGGGGC TGAGAGACAA GGCATGAACT GGTCCTGCAG GACCCCGGAG 1320

CCAAATCCAG TAACAGGGCG ACCGCTCGTT AACATATACA ACTGCTCTGG GGTGCAAGTT 1380

GGAGACAACA ACTACTTGAC TATGCAACAG ACAACTGCCT TGCCCACATG GGGCCTGGCA 1440

CCTTCGGGCA AGGGGAGGGG CTTGCAGCAC CCCCCACCAG TAGGTTCGCA AGAAGGCCCT 1500

AAAGATCCTG AAGCCTGGAG CAGGCCACAG GGTTGGTATA ATCATAGTGG GAAATAA 1557

Domain Profile

S: 1     leelelvgsGgfgkvfkarhrkwrvevavkslvlktdaldserkelleeakkmeklrfsy  60

         le++elvg+Ggfg+vf+a+hrkw+++vavk         ++++k++++e+k+m++l++++

Q: 21    LENQELVGKGGFGTVFRAQHRKWGYDVAVK---------IVNSKAISREVKAMASLDNEF  71

         6899**************************.........999******************

S: 61    vlkllGvikeeek.....lglvmeymenGsLeklLkseielpwplkfRilkevvlgmnyL  115

         vl+l+Gvi+++++      +lv+++menGsL++lL+s++++pwpl +R+lkevvlgm+yL

Q: 72    VLRLEGVIEKVNWdqdpkPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMFYL  131

         *************999999*****************************************

S: 116   hslkPpllhkDLkpeniLlDnelhvkiaDfGlskfmeessqskevsssaegGtlaYlaPe  175

         h+ +P+llh+DLkp+n+LlD+elhvk+aDfGls+f ++ sqs + s+++ gGtl YlaPe

Q: 132   HDRNPVLLHRDLKPSNVLLDPELHVKLADFGLSTF-QGGSQSGTGSGEP-GGTLGYLAPE  189

         ***********************************.*************.**********

S: 176   lleevnkkaseksDvYsfaiviWavlakkepyeeeknslqiiivvkkgnRPeleevseel  235

         l+++vn+kas++sDvYsf+i++Wavla++e++  ++ sl++++v +++nRP+l+e++++

Q: 190   LFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVGNRQNRPSLAELPQAG  249

         ************************************************************

S: 236   Prevpq...lieLmkrcWeadpeeRPsFleieekt  267

         P e+p+   l+eLm+ cW+++p++RPsF+e+ +kt

Q: 250   P-ETPGlegLKELMQLCWSSKPKDRPSFQECLPKT  283

         *.7787788**********************9986

Domain Sequence
(FASTA)

LENQELVGKG GFGTVFRAQH RKWGYDVAVK IVNSKAISRE VKAMASLDNE FVLRLEGVIE 60

KVNWDQDPKP ALVTKFMENG SLSGLLQSQC PRPWPLLCRL LKEVVLGMFY LHDRNPVLLH 120

RDLKPSNVLL DPELHVKLAD FGLSTFQGGS QSGTGSGEPG GTLGYLAPEL FVNVNRKAST 180

ASDVYSFGIL MWAVLAGREV ELPTEPSLVY EAVGNRQNRP SLAELPQAGP ETPGLEGLKE 240

LMQLCWSSKP KDRPSFQECL PKT 263

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Echinops telfairi"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>