EKS-PAT-00038

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00038

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	438.7	6.4E-132	37	303	267

Status

Unreviewed

Ensembl Protein

ENSPTRP00000011431

UniProt Accession

H2Q8W5;

Protein Name

Protein Synonyms/Alias

Vaccinia related kinase 1;

Gene Name

ENSG00000100749

Gene Synonyms/Alias

ENSG00000100749; VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000006705	ENSPTRP00000011431	ENSPTRT00000012345

Organism

Pan troglodytes

Functional Description

Protein Length

396

Protein Sequence
(FASTA)

MPRVKAAQAG RQSSAKRHLA EQFAVGEIIT DMAKKEWKVG LPIGQGGFGC IYLADMNSSE 60

SVGSDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTRKLKYLGV PKYWGSGLHD 120

KNGKSYRFMI MDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA 180

SNLLLNYKNP DQVYLVDYGL AYRYCPEGVH KEYKEDPKRC HDGTIEFTSI DAHNGVAPSR 240

RGDLEILGYC MIQWLTGHLP WEDNLKDPKY VRDSKIRYRE NIASLMDKCF PEKNKPGEIA 300

KYMETVKLLD YTEKPLYENL RDILLQGLKA IGSKDDGKLD LSVVENGGLK AKTITKKRKK 360

EIEESKEPGV EDVEWSNTQT EEAIQTRSRT RKRVQK 396

Nucleotide Sequence
(FASTA)

ATGCCTCGTG TAAAAGCAGC TCAAGCTGGA AGACAGAGCT CTGCAAAGAG ACATCTTGCA 60

GAACAATTTG CAGTTGGAGA GATAATAACT GACATGGCAA AAAAGGAATG GAAAGTAGGA 120

TTACCCATTG GCCAAGGAGG CTTTGGCTGT ATATATCTTG CTGATATGAA TTCTTCAGAG 180

TCAGTTGGCA GTGATGCACC TTGTGTTGTA AAAGTGGAAC CCAGTGACAA TGGACCTCTT 240

TTTACTGAAT TAAAGTTCTA CCAACGAGCT GCAAAACCAG AGCAAATTCA GAAATGGATT 300

CGTACCCGTA AGCTGAAGTA CCTGGGTGTT CCTAAGTATT GGGGGTCTGG TCTACATGAC 360

AAAAATGGTA AAAGTTACAG GTTTATGATA ATGGATCGCT TTGGGAGTGA CCTTCAGAAA 420

ATATATGAAG CAAATGCCAA AAGGTTTTCT CGGAAAACTG TCTTGCAGCT AAGCTTAAGA 480

ATTCTGGATA TTCTGGAATA TATTCACGAG CATGAGTATG TGCATGGCGA TATCAAGGCC 540

TCAAATCTTC TTCTGAACTA CAAGAATCCT GACCAGGTGT ACTTGGTAGA TTATGGCCTT 600

GCTTATCGGT ACTGCCCAGA AGGAGTTCAT AAAGAATACA AAGAAGACCC CAAAAGATGT 660

CACGATGGCA CTATTGAATT CACGAGCATC GACGCACACA ATGGCGTGGC CCCATCAAGA 720

CGTGGTGATT TGGAAATACT TGGTTATTGC ATGATCCAAT GGCTTACTGG CCATCTTCCT 780

TGGGAGGATA ATTTGAAAGA TCCTAAATAT GTTAGAGATT CCAAAATTAG ATACAGAGAA 840

AATATTGCAA GTTTGATGGA CAAATGTTTT CCTGAGAAAA ACAAACCAGG TGAAATTGCC 900

AAATACATGG AAACAGTGAA ATTACTAGAC TACACTGAAA AACCTCTTTA TGAAAATTTA 960

CGTGACATTC TTTTGCAAGG ACTAAAAGCT ATAGGAAGTA AGGATGATGG CAAATTGGAC 1020

CTCAGTGTTG TGGAGAATGG AGGTTTGAAA GCAAAAACAA TAACAAAGAA GCGAAAGAAA 1080

GAAATTGAGG AAAGCAAGGA ACCTGGTGTT GAAGATGTGG AATGGTCAAA CACACAGACA 1140

GAGGAGGCCA TACAGACCCG TTCAAGAACC AGAAAGAGAG TCCAGAAGTA A 1191

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wk+g +ig+ggfG+iyla  ++++++++da +vvkvep++nGpLf+elkfyqraak+eqi

Q: 37    WKVGLPIGQGGFGCIYLAdmNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQI  96

         9*****************99999*************************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         +kw++++klk+lg+P++++sGlh+++g++yRf++++r+g+dLqk++e+n+kr+s+ktvlq

Q: 97    QKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQ  156

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++r+ld+ley+He+eYvHgdikA+nlll++++++qvyLvdyGlayrycpeg+hkeyked

Q: 157   LSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKED  216

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         ++r+HdGt+efts+DaH+GvapsrR+DleiLgYc+++Wltg+LPWe++lkdp++v+++k

Q: 217   PKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKI  276

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         ++ +++++l++k++++k++++e+aky+

Q: 277   RYRENIASLMDKCFPEKNKPGEIAKYM  303

         **************************8

Domain Sequence
(FASTA)

WKVGLPIGQG GFGCIYLADM NSSESVGSDA PCVVKVEPSD NGPLFTELKF YQRAAKPEQI 60

QKWIRTRKLK YLGVPKYWGS GLHDKNGKSY RFMIMDRFGS DLQKIYEANA KRFSRKTVLQ 120

LSLRILDILE YIHEHEYVHG DIKASNLLLN YKNPDQVYLV DYGLAYRYCP EGVHKEYKED 180

PKRCHDGTIE FTSIDAHNGV APSRRGDLEI LGYCMIQWLT GHLPWEDNLK DPKYVRDSKI 240

RYRENIASLM DKCFPEKNKP GEIAKYM 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>