EKS-PAT-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	407.0	6.1E-122	2123	2447	325

Status

Unreviewed

Ensembl Protein

ENSPTRP00000039960

UniProt Accession

H2R014;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000157106

Gene Synonyms/Alias

ENSG00000157106;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000007825	ENSPTRP00000039960	ENSPTRT00000042600

Organism

Pan troglodytes

Functional Description

Protein Length

3661

Protein Sequence
(FASTA)

MSRRAPGSRL SSGGGGGGTK YPRSWNDWEP RTDSASADPD NLKYSSSRDR GGSSSYGLQP 60

SNSAVVSRQR HDDTRVHADI QNDEKGGYSV NGGSGENTYG RKSLGQELRV NNVTSPEFTS 120

VQHGSRALAT KDMRKSQERS MSYSDESRLS NLLRRITRED DRDRRLATVK QLKEFIQQPE 180

NKLVLVKQLD NILAAVHDVL NESSKLLQEL RQEGACCLGL LCASLSYEAE KIFKWIFSKF 240

SSSAKDEVKL LYLCAAYKAL ETVGEKKAFS SVMQLVMTSL QSILENVDTP ELLCKCVKCI 300

LLVARCYPHI FSTNFRDTVD ILVGWHIDHT QKPSLTQQVS GWLQSLEPFW VADLAFSTTL 360

LGQFLEDMEA YAEDLSHVAS GESVDEDVPP PSVSLPKLAA LLRVFSTVVR SIGERFSPIR 420

GPPITEAYVT DVLYRVMRCV TAANQVFFSE AVLTAANECV GVLLGSLDPS MTIHCDMVIT 480

YGLDQLENCQ TCGTDYIISV LNLLTLIVEQ INTKLPSSFV EKLFIPSSKL LFLRYHKEKE 540

VVAVAHAVYQ AVLSLKNIPV LETAYKLILG EMTCALNNLL HSLQLPEACS EIKHEAFTNH 600

VFNVDNAKFV VIFDLSALTT IGNAKNSLIG MWALSPTVFA LLSKNLMIVH SDLAVHFPAI 660

QYAVLYTLYS HCTRHDHFIS SSLSSSSPSL FDGAVISTVT TATKKHFSII LNLLGILLKK 720

DNLNQDTRKL LMTWALEVAV LMKKSETYAP LFSLPSFHKF CKGLLANTLV EDVNICLQAC 780

SSLHALSSSL PDDLLQRCVD VCRVQLVHSG TRIRQAFGKL LKSIPLDVVL SNNNHTEIQE 840

ISLALRSHMS KAPSNTFHPQ DFSDVISFIL YGNSHRTGKD NWLERLFYSC QRLDKRDQST 900

IPRNLLKTDA VLWQWAIWEA AQFTVLSKLR TPLGRAQDTF QTIEGIIRSL AAHTLNPDQD 960

VSQWTTADND EGHGNNQLRL VLLLQYLENL EKLMYNAYEG CANALTSPPK VIRTFFYTNR 1020

QTCQDWLTRI RLSIMRVGLL AGQPAVTVRH GFDLLTEMKT TSLSQGNELE VTIMMVVEAL 1080

CELHCPEAIQ GIAVWSSSIV GKNLLWINSV AQQAEGRFEK ASVEYQEHLC AMTGVDCCIS 1140

SFDKSVLTLA NAGRNSASPK HSLNGESRKT VLSKPTDSSP EVINYLGNKA CECYISIADW 1200

AAVQEWQNAI HDLKKSTSST SLNLKADFNY IKSLSSFESG KFVECTEQLE LLPGENINLL 1260

AGGSKEKIDM KKLLPNMLSP DPRELQKSIE VQLLRSSVCL ATALNPIEQD QKWQSITENV 1320

VKYLKQTSRI AIGPLRLSTL TVSQSLPVLS TLQLYCSSAL ENTVSNRLST EDCLIPLFSE 1380

ALRSCKQHDV RPWMQALRYT MYQNQLLEKI KEQTVPIRSH LMELGLTAAK FARKRGNVSL 1440

ATRLLAQCSE VQLGKTTTAQ DLVQHFKKLS TQGQVDEKWG PELDIEKTKL LYTAGQSTHA 1500

MEMLSSCAIS FCKSVKAEYA VAKSILTLAK WIQAEWKEIS GQLKQVYRAQ HQQNFTGLST 1560

LSKNILTLIE LPSVNTMEEE YPRIESESTV HIGVGEPDFI LGQLYHLSSV QAPEVAKSWA 1620

ALASWAYRWG RKVVDNASQG EGVRLLPREK SEVQNLLPDT ITEEEKERIY GILGQAVCRP 1680

AGIQDEDITL QITESEDNEE DDMVDVIWRQ LISSCPWLSE LDESATEGVI KVWRKVVDRI 1740

FSLYKLSCSA YFTFLKLNAG QIPLDEDDPR LHLSHRVEQS TDDMIVMATL RLLRLLVKHA 1800

GELRQYLEHG LETTPTAPWR GIIPQLFSRL NHPEVYVRQS ICNLLCRVAQ DSPHLILYPA 1860

IVGTISLSSE SQASGNKFST AIPTLLGNIQ GEELLVSECE GGSPPASQDS NKDEPKSGLN 1920

EDQAMMQDCY SKIVDKLSSA NPTMVLQVQM LVAELRRVTV LWDELWLGVL LQQHMYVLRR 1980

IQQLEDEVKR VQNNNTLRKE EKIAIMREKH TALMKPIVFA LEHVRSITAA PAETPHEKWF 2040

QDNYGDAIEN ALEKLKTPSN PAKPGSSWIP FKEIMLSLQQ RAQKRASYIL RLEEISPWLA 2100

AMTNTEIALP GEVSARDTVT IHSVGGTITI LPTKTKPKKL LFLGSDGKSY PYLFKGLEDL 2160

HLDERIMQFL SIVNTMFATI NRQETPRFHA RHYSVTPLGT RSGLIQWVDG ATPLFGLYKR 2220

WQQREAALQA QKAQDSYQTP QNPGIVPRPS ELYYSKIGPA LKTVGLSLDV SRRDWPLHVM 2280

KAVLEELMEA TPPNLLAKEL WSSCTTPDEW WRVTQSYARS TAVMSMVGYI IGLGDRHLDN 2340

VLIDMTTGEV VHIDYNVCFE KGKSLRVPEK VPFRMTQNIE TALGVTGVEG VFRLSCEQVL 2400

HIMRRGRETL LTLLEAFVYD PLVDWTAGGE AGFAGAVYGG GGQQAESKQS KREMEREITR 2460

SLFSSRVAEI KVNWFKNRDE MLVVLPKLDG SLDEYLSLQE QLTDVEKLQG KLLEEIEFLE 2520

GAEGVDHPSH TLQHRYSEHT QLQTQQRAVQ EAIQVKLNEF EQWITHYQAA FNNLEATQLA 2580

SLLQEISTQM DLGPPSYVPA TAFLQNAGQA HLISQCEQLE GEVGALLQQR RSVLRGCLEQ 2640

LHHYATVALQ YPKAIFQKHR IEQWKTWMEE LICNTTVERC QELYRKYEMQ YAPQPPPTVC 2700

QFITATEMTL QRYAADINSR LIRQVERLKQ EAVTVPVCED QLKEIERCIK VFLHENGEEG 2760

SLSLASVIIS ALCTLTRRNL MMEGAASSAG EQLVDLTSRD GAWFLEELCS MSGNVTCLVQ 2820

LLKQCHLVPQ DLDIPNPMEA SETVHLANGV YTSLQELNSN FRQIIFPEAL RCLMKGEYTL 2880

ESMLHELDGL IEQTTDGVPL QTLVESLQAY LRNAAMGLEE ETHAHYIDVA RLLHAQYGEL 2940

IQPRNGSVDE TPKMSAGQML LVAFDGMFAQ VETAFSLLVE KLNKMEIPIA WRKIDIIREA 3000

RSTQVNFFDD DNHRQVLEEI FFLKRLQTIK EFFRLCGTFS KTLSGSSSLE DQNTVNGPVQ 3060

IVNVKTLFRN SCFSEDQMAK PIKAFTADFV RQLLIGLPNQ ALGLTLCSFI SALGVDIIAQ 3120

VEAKDFGAES KVSVDDLCKK AVEHNIQIGK FSQLVMNRAT VLASSYDTAW KKHDLVRRLE 3180

TSISSCKTSL QRVQLHIAMF QWQHEDLLIN RPQAMSVTPP PRSAILTSMK KKLHTLSQIE 3240

TSIATVQEKL AALESSIEQR LKWAGGANPA LAPVLQDFEA TIAERRNLVL KESQRASQVT 3300

FLCSNIIHFE SLRTRTAEAL NLDAALFELI KRCQQMCSFA SQFNSSVSEL ELRLLQRVDT 3360

GLEHPIGSSE WLLSAHKQLT QDMSTQRAIQ TEKEQQIETV CETIQNLVDN IKTVLTGHNR 3420

QLGDVKHLLK AMAKDEEAAL ADGEDVPYEN SVRQFLGEYK SWQDNIQTVL FTLVQAMGQV 3480

RSQEHVEMLQ EITPTLKELK TQSQSIYNNL VSFASPLVTD ATNECSSPTS SATYQPSFAA 3540

AVRSNTGQKT QPDVMSQNAR KLIQKNLATS ADTPPSTVPG TGKSVACSPK KAVRDPKTGK 3600

AVQERNSYAV SVWKRVKAKL EGRDVDPNRR MSVAEQVDYV IKEATNLDNL AQLYEGWTAW 3660

V 3661

Nucleotide Sequence
(FASTA)

ATGAGCCGCA GAGCCCCGGG GTCTCGGCTG AGCAGCGGCG GCGGCGGCGG CGGCACCAAG 60

TATCCGCGGA GCTGGAATGA CTGGGAACCC AGAACTGATA GTGCATCAGC CGACCCAGAT 120

AATTTAAAAT ATTCTTCATC CAGAGATAGA GGTGGTTCTT CCTCTTATGG ACTGCAACCT 180

TCAAATTCAG CTGTGGTGTC TCGGCAAAGG CACGATGATA CCAGAGTCCA CGCTGACATA 240

CAGAATGACG AAAAGGGTGG CTACAGTGTC AATGGAGGAT CTGGGGAAAA TACTTATGGT 300

CGGAAGTCGT TGGGGCAAGA GCTGAGGGTT AACAATGTGA CCAGCCCTGA GTTCACCAGT 360

GTTCAGCATG GCAGTCGTGC TTTAGCCACC AAAGACATGA GGAAATCACA GGAGAGATCG 420

ATGTCTTATT CTGATGAGTC TCGACTGTCG AATCTTCTTC GGAGGATCAC CCGGGAAGAC 480

GACAGAGACC GAAGATTGGC TACTGTAAAG CAGTTGAAAG AATTTATTCA GCAACCAGAA 540

AATAAGCTGG TACTAGTTAA ACAATTGGAT AATATCTTGG CTGCTGTACA TGACGTGCTT 600

AATGAAAGTA GCAAATTGCT TCAGGAGTTG AGACAGGAGG GAGCTTGCTG TCTCGGCCTT 660

CTTTGTGCTT CTCTGAGCTA TGAGGCTGAG AAGATCTTCA AGTGGATTTT TAGCAAATTT 720

AGCTCATCTG CAAAAGATGA AGTTAAACTC CTCTACTTAT GTGCCGCCTA CAAAGCACTA 780

GAGACTGTAG GAGAAAAGAA AGCCTTTTCA TCTGTAATGC AGCTTGTAAT GACCAGCCTG 840

CAGTCTATTC TTGAAAATGT GGATACACCG GAATTGCTTT GTAAATGTGT TAAGTGCATT 900

CTTTTGGTGG CTCGATGTTA CCCTCATATT TTCAGCACTA ATTTTAGGGA TACAGTTGAT 960

ATATTAGTTG GATGGCATAT AGATCATACT CAGAAACCTT CGCTCACGCA GCAGGTATCT 1020

GGGTGGTTGC AGAGTTTGGA GCCATTTTGG GTAGCTGATC TTGCATTTTC TACTACTCTT 1080

CTTGGTCAGT TTCTAGAAGA CATGGAAGCA TATGCTGAGG ACCTCAGCCA TGTGGCCTCT 1140

GGGGAATCAG TGGATGAAGA TGTCCCTCCT CCATCAGTGT CATTACCAAA GCTGGCTGCG 1200

CTTCTCCGGG TATTTAGTAC TGTGGTGAGG AGCATTGGGG AACGCTTCAG CCCAATTCGG 1260

GGTCCTCCAA TTACTGAGGC ATATGTAACA GATGTTCTGT ACAGAGTAAT GAGATGTGTG 1320

ACGGCTGCAA ACCAGGTGTT TTTTTCTGAG GCTGTGTTGA CAGCTGCTAA TGAGTGTGTT 1380

GGTGTTTTGC TCGGCAGCTT GGATCCTAGC ATGACTATAC ATTGTGACAT GGTCATTACA 1440

TATGGATTAG ACCAACTGGA GAATTGCCAG ACTTGTGGTA CCGATTATAT CATCTCAGTC 1500

TTGAATTTAC TCACGCTGAT TGTTGAACAG ATAAATACGA AACTGCCGTC ATCATTTGTA 1560

GAAAAACTGT TTATACCATC ATCTAAACTA CTATTCTTGC GTTATCATAA AGAAAAAGAG 1620

GTTGTTGCTG TAGCCCATGC TGTTTATCAA GCAGTGCTCA GCTTGAAGAA TATTCCTGTT 1680

TTGGAGACTG CCTATAAGTT AATATTGGGA GAAATGACTT GTGCCCTAAA CAACCTCCTG 1740

CACAGTCTAC AACTTCCTGA GGCCTGTTCT GAAATAAAAC ATGAGGCTTT TACGAATCAT 1800

GTGTTCAATG TAGACAATGC AAAATTTGTA GTTATATTTG ACCTCAGTGC CCTGACTACA 1860

ATTGGAAATG CCAAAAACTC ACTAATAGGG ATGTGGGCGC TATCTCCAAC TGTCTTTGCA 1920

CTTCTGAGTA AGAATCTGAT GATTGTGCAC AGTGACCTGG CTGTTCACTT CCCTGCTATT 1980

CAGTATGCTG TGCTCTACAC ATTGTATTCT CATTGTACCA GGCATGATCA CTTTATCTCT 2040

AGTAGCCTCA GTTCTTCCTC TCCTTCTTTG TTTGATGGAG CTGTGATTAG CACTGTAACT 2100

ACGGCTACAA AGAAACATTT TTCAATTATA TTAAATCTTC TGGGAATATT ACTTAAGAAA 2160

GATAACCTTA ACCAGGACAC GAGGAAACTG TTAATGACTT GGGCTTTGGA AGTAGCTGTT 2220

TTAATGAAGA AGTCTGAAAC ATACGCACCT TTATTCTCTC TCCCGTCTTT CCATAAATTT 2280

TGCAAAGGCC TTTTAGCCAA CACTCTCGTT GAAGATGTGA ATATCTGTCT GCAGGCATGC 2340

AGCAGTCTAC ATGCTCTGTC CTCTTCCTTG CCAGATGATC TTTTACAGAG ATGTGTTGAT 2400

GTTTGCCGTG TTCAACTAGT GCACAGTGGA ACTCGTATTC GACAAGCATT TGGAAAACTG 2460

TTGAAATCAA TTCCTTTAGA TGTTGTCCTA AGCAATAACA ATCACACAGA AATTCAAGAA 2520

ATTTCTTTAG CATTAAGAAG TCACATGAGT AAAGCACCAA GTAATACATT CCACCCCCAA 2580

GATTTCTCTG ATGTTATTAG TTTTATTTTG TATGGGAACT CTCATAGAAC AGGGAAGGAC 2640

AATTGGTTGG AAAGACTGTT CTATAGCTGC CAGAGACTGG ATAAGCGTGA CCAGTCAACA 2700

ATTCCACGCA ATCTCCTGAA GACAGATGCT GTCCTTTGGC AGTGGGCTAT ATGGGAAGCT 2760

GCACAATTCA CTGTTCTTTC TAAGCTGAGA ACCCCACTGG GCAGAGCTCA AGACACCTTC 2820

CAGACAATTG AAGGTATCAT TCGAAGTCTC GCAGCTCACA CATTAAACCC TGATCAGGAT 2880

GTTAGTCAGT GGACAACTGC AGACAATGAT GAAGGCCATG GTAACAACCA ACTTAGACTT 2940

GTTCTTCTTC TGCAGTATCT GGAAAATCTG GAGAAATTAA TGTATAATGC ATACGAGGGA 3000

TGTGCTAATG CATTAACTTC ACCTCCCAAG GTCATTAGAA CTTTTTTCTA TACCAATCGC 3060

CAAACTTGTC AGGACTGGCT AACGCGGATT CGACTCTCCA TCATGAGGGT AGGATTGTTG 3120

GCAGGCCAGC CTGCAGTGAC AGTGAGACAT GGCTTTGACT TGCTTACAGA GATGAAAACA 3180

ACCAGCCTAT CTCAGGGGAA TGAATTGGAA GTAACCATTA TGATGGTGGT AGAAGCACTA 3240

TGTGAACTTC ATTGTCCTGA AGCTATACAG GGAATTGCTG TCTGGTCGTC ATCTATTGTT 3300

GGAAAAAATC TTCTGTGGAT TAACTCAGTG GCTCAACAGG CTGAAGGGAG GTTTGAAAAG 3360

GCCTCTGTGG AGTACCAGGA ACACCTGTGT GCCATGACAG GTGTTGATTG CTGCATCTCC 3420

AGCTTTGACA AATCGGTGCT CACCTTAGCC AATGCTGGGC GTAACAGTGC CAGCCCGAAA 3480

CATTCTCTGA ATGGTGAATC CAGAAAAACT GTGCTGTCCA AACCGACTGA CTCTTCCCCT 3540

GAGGTTATAA ATTATTTAGG AAATAAAGCA TGTGAGTGCT ACATCTCAAT TGCCGATTGG 3600

GCTGCTGTGC AGGAATGGCA GAACGCTATC CATGACTTGA AAAAGAGTAC CAGTAGCACT 3660

TCCCTCAACC TGAAAGCTGA CTTCAACTAT ATAAAATCAT TAAGCAGCTT TGAGTCTGGA 3720

AAATTTGTTG AATGTACCGA GCAATTAGAA TTGTTACCAG GAGAAAATAT CAATCTACTT 3780

GCTGGAGGAT CAAAAGAAAA AATAGACATG AAAAAACTGC TTCCTAACAT GTTAAGTCCA 3840

GATCCAAGGG AACTTCAGAA ATCCATTGAA GTTCAATTGT TAAGAAGTTC TGTTTGTTTG 3900

GCAACTGCTT TAAACCCGAT AGAACAAGAT CAGAAGTGGC AGTCTATAAC TGAAAATGTG 3960

GTAAAGTACT TGAAGCAAAC ATCCCGTATC GCTATTGGAC CTCTGAGACT TTCTACTTTA 4020

ACAGTTTCAC AGTCTTTGCC AGTTCTAAGT ACCTTGCAGC TGTATTGCTC ATCTGCTTTG 4080

GAGAACACAG TTTCTAACAG ACTTTCAACA GAGGACTGTC TTATTCCACT CTTCAGTGAA 4140

GCTTTACGTT CATGTAAACA GCATGACGTG AGGCCATGGA TGCAGGCATT AAGGTATACT 4200

ATGTACCAGA ATCAGCTGTT GGAGAAAATT AAAGAACAAA CAGTCCCAAT TAGAAGCCAT 4260

CTCATGGAAT TAGGTCTAAC TGCAGCAAAA TTTGCTAGAA AACGAGGGAA TGTGTCCCTT 4320

GCAACAAGAC TGCTGGCACA GTGCAGTGAA GTTCAGCTGG GAAAGACCAC CACTGCACAG 4380

GATTTAGTCC AACATTTTAA AAAACTATCA ACCCAAGGTC AAGTGGATGA AAAATGGGGG 4440

CCCGAACTTG ATATTGAAAA AACCAAATTG CTATATACAG CAGGCCAGTC AACACATGCA 4500

ATGGAAATGT TGAGTTCTTG TGCCATATCT TTCTGCAAGT CTGTGAAAGC TGAATATGCA 4560

GTTGCTAAGT CAATTCTGAC ACTGGCTAAA TGGATCCAGG CAGAATGGAA AGAGATTTCA 4620

GGACAGCTGA AACAGGTTTA CAGAGCTCAG CACCAACAGA ACTTCACAGG TCTTTCTACT 4680

TTGTCTAAAA ACATACTCAC TCTAATAGAA CTGCCATCTG TTAATACGAT GGAAGAAGAG 4740

TATCCTCGGA TCGAGAGTGA ATCTACAGTG CATATTGGAG TTGGAGAACC TGACTTCATT 4800

TTGGGACAGT TGTATCACCT ATCTTCAGTA CAGGCACCTG AAGTAGCCAA ATCTTGGGCA 4860

GCATTGGCCA GCTGGGCTTA TAGGTGGGGC AGAAAGGTGG TTGACAATGC CAGTCAGGGA 4920

GAAGGTGTTC GTCTGCTGCC TAGAGAAAAA TCTGAAGTTC AGAATCTGCT TCCAGACACT 4980

ATAACTGAGG AAGAGAAAGA GAGAATATAT GGTATTCTTG GACAGGCTGT GTGTCGGCCG 5040

GCGGGGATTC AGGATGAAGA TATAACACTT CAGATAACAG AGAGTGAAGA TAACGAAGAA 5100

GATGACATGG TTGATGTTAT CTGGCGTCAG TTGATATCAA GCTGCCCATG GCTTTCAGAA 5160

CTTGATGAAA GTGCAACTGA AGGAGTTATT AAAGTGTGGA GGAAAGTTGT AGATAGAATA 5220

TTCAGCCTGT ACAAACTCTC TTGCAGTGCA TACTTTACTT TCCTTAAACT CAACGCTGGT 5280

CAAATTCCTT TAGATGAGGA TGACCCTAGG CTGCATTTAA GTCACAGAGT GGAACAGAGC 5340

ACTGATGACA TGATCGTGAT GGCCACATTG CGCCTGCTGC GGTTGCTCGT GAAGCACGCT 5400

GGTGAGCTTC GGCAGTATCT GGAGCACGGC TTGGAGACAA CACCCACTGC ACCATGGAGA 5460

GGAATTATTC CGCAACTTTT CTCACGCTTA AACCACCCTG AAGTGTATGT GCGCCAGAGT 5520

ATTTGTAACC TTCTCTGCCG TGTGGCTCAA GATTCCCCAC ATCTCATATT GTATCCTGCA 5580

ATAGTGGGTA CCATATCGCT TAGTAGTGAA TCCCAGGCTT CAGGAAATAA ATTTTCCACT 5640

GCAATTCCAA CTTTACTTGG CAATATTCAA GGAGAAGAAT TGCTGGTTTC TGAATGTGAG 5700

GGAGGAAGTC CTCCTGCATC TCAGGATAGC AATAAGGATG AACCTAAAAG TGGATTAAAT 5760

GAAGACCAAG CCATGATGCA GGATTGTTAC AGCAAAATTG TAGATAAGCT GTCCTCTGCA 5820

AACCCCACCA TGGTATTACA GGTTCAGATG CTCGTGGCTG AACTGCGCAG GGTCACTGTG 5880

CTCTGGGATG AGCTCTGGCT GGGAGTTTTG CTGCAACAAC ACATGTACGT CCTGAGACGA 5940

ATTCAGCAGC TTGAAGATGA GGTGAAGAGA GTCCAGAACA ACAACACCTT ACGCAAAGAA 6000

GAGAAAATTG CAATCATGCG GGAGAAGCAC ACAGCTTTGA TGAAGCCCAT CGTATTTGCT 6060

TTGGAGCATG TGAGGAGTAT CACAGCGGCT CCTGCAGAAA CACCTCATGA AAAATGGTTT 6120

CAGGATAACT ATGGTGATGC CATTGAAAAT GCCCTAGAAA AACTGAAGAC TCCATCGAAC 6180

CCTGCAAAGC CTGGGAGCAG CTGGATTCCA TTTAAAGAGA TAATGCTAAG TTTGCAACAG 6240

AGAGCACAGA AACGTGCAAG TTACATCTTG CGTCTTGAAG AAATCAGTCC ATGGTTGGCT 6300

GCCATGACTA ACACTGAAAT TGCTCTTCCT GGGGAAGTCT CAGCCAGAGA CACTGTCACA 6360

ATCCATAGTG TGGGCGGAAC CATCACAATC TTACCGACTA AAACCAAGCC AAAGAAACTT 6420

CTCTTTCTTG GATCAGATGG GAAGAGCTAT CCTTATCTTT TCAAAGGACT GGAGGATTTA 6480

CATTTGGATG AGAGAATAAT GCAATTCCTA TCTATTGTGA ATACCATGTT TGCTACAATT 6540

AATCGCCAAG AAACACCCCG GTTCCATGCT CGACACTATT CTGTAACACC ACTAGGAACA 6600

AGATCAGGAC TAATCCAATG GGTAGATGGA GCCACACCCT TATTTGGTCT TTACAAACGA 6660

TGGCAACAAC GGGAAGCTGC CTTACAAGCA CAAAAGGCCC AAGATTCCTA CCAAACTCCT 6720

CAGAATCCTG GAATTGTACC CCGTCCTAGT GAACTTTATT ACAGTAAAAT TGGCCCTGCT 6780

TTGAAAACAG TTGGGCTTAG CCTGGATGTG TCCCGTCGGG ATTGGCCTCT TCATGTAATG 6840

AAGGCAGTAT TGGAAGAGTT AATGGAGGCC ACACCCCCGA ATCTCCTTGC CAAAGAGCTC 6900

TGGTCATCTT GCACAACACC TGATGAATGG TGGAGAGTTA CGCAGTCTTA TGCAAGATCT 6960

ACTGCAGTCA TGTCTATGGT TGGATACATA ATTGGCCTTG GAGACAGACA TCTGGATAAT 7020

GTTCTTATAG ATATGACGAC TGGAGAAGTT GTTCACATAG ATTACAATGT TTGCTTTGAA 7080

AAAGGTAAAA GCCTTAGAGT TCCTGAGAAA GTACCTTTTC GAATGACACA AAACATTGAA 7140

ACAGCACTGG GTGTAACTGG AGTAGAAGGT GTATTTAGGC TTTCATGTGA GCAGGTTTTA 7200

CACATTATGC GGCGTGGCAG AGAGACCCTG CTGACGCTGC TGGAGGCCTT TGTGTACGAC 7260

CCTCTGGTGG ACTGGACAGC AGGAGGCGAG GCTGGGTTTG CTGGTGCTGT CTATGGTGGA 7320

GGTGGCCAGC AGGCCGAGAG CAAGCAGAGC AAGAGAGAGA TGGAGCGAGA GATCACCCGC 7380

AGCCTGTTTT CTTCTAGAGT AGCTGAGATT AAGGTGAACT GGTTTAAGAA TAGAGATGAG 7440

ATGCTGGTTG TGCTTCCCAA GTTGGACGGT AGCTTAGATG AATACCTAAG CTTGCAAGAG 7500

CAACTGACAG ATGTGGAAAA ACTGCAGGGC AAACTACTGG AGGAAATAGA GTTTCTAGAA 7560

GGAGCTGAAG GGGTGGATCA TCCTTCTCAT ACTCTGCAAC ACAGGTATTC TGAACACACC 7620

CAACTACAGA CTCAGCAAAG AGCTGTTCAG GAAGCAATCC AGGTGAAGCT GAATGAATTT 7680

GAACAATGGA TAACACATTA TCAGGCTGCA TTCAATAATT TAGAAGCAAC ACAGCTTGCA 7740

AGCTTGCTTC AAGAGATAAG CACACAAATG GACCTTGGTC CTCCAAGTTA CGTGCCAGCA 7800

ACAGCCTTTC TGCAGAATGC TGGTCAGGCC CACTTGATTA GCCAGTGCGA GCAGCTGGAG 7860

GGGGAGGTTG GTGCTCTCCT GCAGCAGAGG CGCTCCGTGC TCCGTGGCTG TCTGGAGCAA 7920

CTGCATCACT ATGCAACCGT GGCTCTGCAG TATCCGAAGG CCATATTTCA GAAACATCGA 7980

ATTGAACAGT GGAAGACCTG GATGGAAGAG CTCATCTGTA ACACCACAGT AGAGCGTTGT 8040

CAAGAGCTCT ATAGGAAATA TGAAATGCAA TATGCTCCCC AGCCACCCCC AACAGTGTGT 8100

CAGTTCATCA CTGCCACTGA AATGACCCTG CAGCGATACG CAGCAGACAT CAACAGCAGA 8160

CTTATTAGAC AAGTGGAACG CTTGAAACAG GAAGCTGTCA CTGTGCCAGT TTGTGAAGAT 8220

CAGTTGAAAG AAATTGAACG TTGCATTAAA GTTTTCCTTC ATGAGAATGG AGAAGAAGGA 8280

TCTTTGAGTC TAGCAAGTGT TATTATTTCT GCCCTTTGTA CCCTTACAAG GCGTAACCTG 8340

ATGATGGAAG GTGCAGCGTC AAGTGCTGGA GAACAGCTGG TTGATCTGAC TTCTCGGGAT 8400

GGAGCCTGGT TCTTGGAGGA ACTCTGCAGT ATGAGCGGAA ACGTCACCTG CTTGGTTCAG 8460

TTACTGAAGC AGTGCCACCT GGTGCCACAG GACTTAGATA TCCCGAACCC CATGGAAGCG 8520

TCTGAGACAG TTCACTTAGC CAATGGAGTG TATACCTCAC TTCAGGAATT GAATTCGAAT 8580

TTCCGGCAAA TCATATTTCC AGAAGCACTT CGATGTTTAA TGAAAGGGGA ATACACGTTA 8640

GAAAGTATGC TGCATGAACT GGACGGTCTT ATTGAGCAGA CCACCGATGG CGTTCCCCTG 8700

CAGACTCTAG TGGAATCTCT TCAGGCCTAC TTAAGAAACG CAGCTATGGG ACTGGAAGAA 8760

GAAACACATG CTCATTACAT CGATGTTGCC AGACTACTAC ATGCTCAGTA CGGTGAATTA 8820

ATCCAACCGA GAAATGGTTC AGTTGATGAA ACACCCAAAA TGTCAGCTGG CCAGATGCTT 8880

TTGGTAGCAT TCGATGGCAT GTTTGCTCAA GTTGAAACTG CTTTCAGCTT ATTAGTTGAA 8940

AAGTTGAACA AGATGGAAAT TCCCATAGCT TGGCGAAAGA TTGACATCAT AAGGGAAGCC 9000

AGGAGTACTC AAGTTAATTT TTTTGATGAT GATAATCACC GGCAGGTGCT AGAAGAGATT 9060

TTCTTTCTAA AAAGACTACA GACTATTAAG GAGTTCTTCA GGCTCTGTGG TACCTTTTCT 9120

AAAACATTGT CAGGATCAAG TTCACTTGAA GATCAGAATA CTGTGAATGG GCCTGTACAG 9180

ATTGTCAATG TGAAAACCCT TTTTAGAAAC TCTTGTTTCA GTGAAGACCA AATGGCCAAA 9240

CCTATCAAGG CATTCACAGC TGACTTTGTG AGGCAGCTCT TGATAGGGCT ACCCAACCAA 9300

GCCCTCGGAC TCACACTGTG CAGTTTTATC AGTGCTCTGG GTGTAGACAT CATTGCTCAA 9360

GTAGAGGCAA AGGACTTTGG TGCCGAAAGC AAAGTTTCTG TTGATGATCT CTGTAAGAAA 9420

GCGGTGGAAC ATAACATCCA GATAGGGAAG TTCTCTCAGC TGGTTATGAA CAGGGCAACT 9480

GTGTTAGCAA GTTCTTACGA CACTGCCTGG AAGAAGCATG ACTTGGTGCG AAGGCTAGAA 9540

ACCAGTATTT CTTCTTGTAA GACAAGCCTG CAGCGGGTTC AGCTGCATAT TGCCATGTTT 9600

CAGTGGCAAC ATGAAGATCT ACTTATCAAT AGACCACAAG CCATGTCAGT CACACCTCCC 9660

CCACGGTCTG CTATCCTAAC CAGCATGAAA AAGAAGCTGC ATACCCTGAG CCAGATTGAA 9720

ACTTCTATTG CAACAGTTCA GGAGAAGCTA GCTGCACTTG AATCAAGTAT TGAACAGCGA 9780

CTCAAGTGGG CAGGTGGTGC CAACCCTGCA TTGGCCCCTG TACTACAAGA TTTTGAAGCA 9840

ACGATAGCTG AAAGAAGAAA TCTTGTCCTT AAAGAGAGCC AAAGAGCAAG TCAGGTCACA 9900

TTTCTCTGCA GCAATATCAT TCATTTTGAA AGTTTACGAA CAAGAACTGC AGAAGCCTTA 9960

AACCTGGATG CGGCGTTATT TGAACTAATC AAGCGATGTC AGCAGATGTG TTCGTTTGCA 10020

TCACAGTTTA ACAGTTCAGT GTCTGAGTTA GAGCTTCGTT TATTACAGAG AGTGGACACT 10080

GGTCTTGAAC ATCCTATTGG CAGCTCTGAA TGGCTTTTGT CAGCACACAA ACAGTTGACC 10140

CAGGATATGT CTACTCAGAG GGCAATTCAG ACAGAGAAAG AGCAGCAGAT AGAAACGGTC 10200

TGTGAAACAA TTCAGAATCT GGTTGATAAT ATAAAGACTG TGCTCACTGG TCATAACCGA 10260

CAGCTTGGAG ATGTCAAACA TCTCTTGAAA GCTATGGCTA AGGATGAAGA AGCTGCTCTG 10320

GCAGATGGTG AAGATGTTCC CTATGAGAAC AGTGTTAGGC AGTTTTTGGG TGAATATAAA 10380

TCATGGCAAG ACAACATTCA AACAGTTCTA TTTACATTAG TCCAGGCTAT GGGTCAGGTT 10440

CGAAGTCAAG AACACGTTGA AATGCTCCAG GAAATCACTC CCACCTTGAA AGAACTGAAA 10500

ACACAAAGTC AGAGTATCTA TAATAATTTA GTGAGTTTTG CATCACCCTT AGTCACCGAT 10560

GCAACAAATG AATGTTCAAG TCCAACGTCA TCTGCTACTT ATCAGCCATC CTTCGCTGCA 10620

GCAGTCCGGA GTAACACTGG CCAGAAGACT CAGCCTGATG TCATGTCACA GAATGCTAGA 10680

AAGCTGATCC AGAAAAATCT TGCTACATCA GCTGATACTC CACCAAGCAC CGTTCCAGGA 10740

ACTGGCAAGA GTGTTGCTTG TAGTCCTAAA AAGGCAGTCA GAGACCCTAA AACTGGGAAA 10800

GCGGTGCAAG AGAGAAACTC CTATGCAGTG AGTGTGTGGA AGAGAGTGAA AGCCAAGTTA 10860

GAGGGCCGAG ATGTTGATCC GAATAGGAGG ATGTCAGTTG CTGAACAGGT TGACTATGTC 10920

ATTAAGGAAG CAACTAATCT AGATAACTTG GCTCAGCTGT ATGAAGGTTG GACAGCCTGG 10980

GTGTGA 10986

Domain Profile

S: 3     gfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdke  62

         ++  +++il++k+kpkkll++Gsdgk+ypyL+kg+eDl+ der++q++s+vNt++a+ ++

Q: 2123  SVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINR  2182

         566789******************************************************

S: 63    tsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpi..syrykdl  120

         ++++++++r+y+V+pl+trsgli+wv+++++L+ l+k++++++a+l++q++  sy+++++

Q: 2183  QETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAqdSYQTPQN  2242

         **************************************************999*******

S: 121   stvqar.........kpklkhlkls.........levfkevlenlv...pkdllkkllle  159

         + +++r         +p+lk++ ls         l+v+k+vle+l+   p++ll+k+l++

Q: 2243  PGIVPRpselyyskiGPALKTVGLSldvsrrdwpLHVMKAVLEELMeatPPNLLAKELWS  2302

         ***************999999999999*****************99999***********

S: 160   kfpspeewfelrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafeka  219

         ++++p+ew++++++y+rs+Av+s+vgyi+gLgdrhl+n+lid++tgevvhid++v+fek+

Q: 2303  SCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKG  2362

         ************************************************************

S: 220   ktqlkvpekvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydp  279

         k+ l+vpekvPFR+T+ni++algvtgveGvfr sce+vl+++r+ +e+llt+Le+f+ydp

Q: 2363  KS-LRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDP  2421

         **.*********************************************************

S: 280   lvdwkk...................k  286

         lvdw+                    +

Q: 2422  LVDWTAggeagfagavyggggqqaeS  2447

         *****988777777666555522222

Domain Sequence
(FASTA)

SVGGTITILP TKTKPKKLLF LGSDGKSYPY LFKGLEDLHL DERIMQFLSI VNTMFATINR 60

QETPRFHARH YSVTPLGTRS GLIQWVDGAT PLFGLYKRWQ QREAALQAQK AQDSYQTPQN 120

PGIVPRPSEL YYSKIGPALK TVGLSLDVSR RDWPLHVMKA VLEELMEATP PNLLAKELWS 180

SCTTPDEWWR VTQSYARSTA VMSMVGYIIG LGDRHLDNVL IDMTTGEVVH IDYNVCFEKG 240

KSLRVPEKVP FRMTQNIETA LGVTGVEGVF RLSCEQVLHI MRRGRETLLT LLEAFVYDPL 300

VDWTAGGEAG FAGAVYGGGG QQAES 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

ptr:453961

;

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR014009	; PIK_FAT.

Pfam

PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013