EKS-PAT-00273

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00273

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	444.8	9.8E-134	568	829	262

Status

Unreviewed

Ensembl Protein

ENSPTRP00000013476

UniProt Accession

H2QAS4;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000134398

Gene Synonyms/Alias

ENSG00000134398;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000007893	ENSPTRP00000013476	ENSPTRT00000014545

Organism

Pan troglodytes

Functional Description

Protein Length

974

Protein Sequence
(FASTA)

MRRAGIGEDS RLGLQAQPGA EPSPGRAGTE RSPGGTQGPG QPCSCPGAMA SAVRGSRPWP 60

RLGLQLQFAA LLLGTLSPQV HTLRPENLLL VSTLDGSLHA LSKQTGDLKW TLRDDPVIEG 120

PTYVTEMAFL SDPADGSLYI LGTQKQQGLM KLPFTIPELV HASPCRSSDG VFYTGRKQDA 180

WFVVDPESGE TQMTLTTEGP STPRLYIGRT QYTVTMHDPR APALRWNTTY RRYSAPPMDG 240

SPGKYMSHLA SCGMGLLLTV DPGSGTVLWT QDLGVPVMGI YTWHQDGLRQ LPHLTLARDT 300

LHFLALRWGH IRLPASGPQD TATLFSTLDT QLLMTLYVGK DETGFYVSKA LVHTAVALVP 360

RGLTLAPADG PTTDEVTLQV SGEREGSPST AVRYPSGSVA LPSQWLLIGH HELPPVLHTT 420

MLRVHPTLGS GTAETRPPEN TQAPAFFLEL LSLSREKLWD SELHPEEKTP DSYLGLGPQD 480

LLAASLTAVL LGGWILFVMR QQQPQVVEKQ QETPLASADS AHISQDAQSL HSGATRRSQK 540

RFQSPSKQAQ PLDDPEAEQL TVVGKISFNP KDVLGRGAGG TFVFRGQFEG RAVAVKRLLR 600

ECFGLVRREV QLLQESDRHP NVLRYFCTER GPQFHYIALE LCRASLQEYV ENPDLDRGGL 660

EPEVVLQQLM SGLAHLHSLH IVHRDLKPGN ILITGPDSQG LGRVVLSDFG LCKKLPAGRC 720

SFSLHSGIPG TEGWMAPELL QLLPPDSPTS AVDIFSAGCV FYYVLSGGSH PFGDSLYRQA 780

NILTGAPCLA HLEEEVHDKV VARDLVGAML SPLPQPRPSA PQVLAHPFFW SRAKQLQFFQ 840

DVSDWLEKES EQEPLVRALE AGGCAVVRDN WHKHISMPLQ TDLRKFRSYK GTSVRDLLRA 900

VRNKKHHYRE LPVEVRQALG QVPDGFVQYF TNRFPRLLLH THRAMRSCAS ESLFLPYYPP 960

DSEARRPCPG AAGR 974

Nucleotide Sequence
(FASTA)

ATGAGAAGGG CAGGGATCGG CGAGGACTCC AGGCTGGGGT TGCAGGCCCA GCCAGGGGCG 60

GAGCCTTCTC CGGGTCGGGC GGGGACAGAG CGCTCCCCTG GAGGCACCCA GGGACCTGGC 120

CAGCCGTGCA GCTGCCCAGG CGCTATGGCG AGTGCGGTCA GGGGGTCGAG GCCGTGGCCC 180

CGGCTGGGGC TCCAGCTCCA GTTCGCGGCG CTGCTGCTCG GGACGCTGAG TCCACAGGTT 240

CATACTCTCA GGCCAGAGAA CCTCCTGCTG GTGTCCACCT TGGATGGAAG TCTCCACGCA 300

CTAAGCAAGC AGACAGGGGA CCTGAAGTGG ACTCTGAGGG ATGATCCCGT CATCGAAGGA 360

CCAACGTACG TCACGGAAAT GGCCTTTCTC TCTGACCCAG CAGATGGCAG CCTGTACATC 420

TTGGGGACCC AAAAACAACA GGGATTAATG AAACTGCCAT TCACCATCCC TGAGCTGGTT 480

CATGCCTCTC CCTGCCGCAG CTCTGATGGG GTCTTCTACA CAGGCCGGAA GCAGGATGCC 540

TGGTTTGTGG TGGACCCTGA GTCAGGGGAG ACCCAGATGA CACTGACCAC AGAGGGTCCC 600

TCCACCCCCC GCCTCTACAT TGGCCGAACA CAGTATACGG TCACCATGCA TGACCCAAGA 660

GCCCCAGCCC TGCGCTGGAA CACCACCTAC CGCCGCTACT CAGCGCCCCC CATGGATGGC 720

TCACCTGGGA AATACATGAG CCACCTGGCG TCCTGCGGGA TGGGCCTGCT GCTCACTGTG 780

GACCCAGGAA GCGGGACGGT GCTGTGGACA CAGGACCTGG GCGTGCCTGT GATGGGCATC 840

TACACCTGGC ACCAGGACGG CCTGCGCCAG CTGCCGCATC TCACGCTGGC TCGAGACACT 900

CTGCATTTCC TCGCCCTCCG CTGGGGCCAC ATCCGACTGC CTGCCTCAGG CCCCCAGGAC 960

ACAGCCACCC TCTTCTCTAC CTTGGACACC CAGCTGCTAA TGACGCTGTA TGTGGGGAAG 1020

GATGAAACTG GCTTCTATGT CTCTAAAGCA CTGGTCCACA CAGCAGTGGC CCTGGTGCCT 1080

CGTGGACTGA CCCTGGCCCC CGCAGATGGC CCCACCACAG ATGAGGTGAC ACTCCAAGTC 1140

TCAGGAGAGC GAGAGGGCTC ACCCAGCACT GCTGTTAGAT ACCCCTCAGG CAGTGTGGCC 1200

CTCCCAAGCC AGTGGCTGCT CATTGGACAC CACGAGCTAC CCCCAGTCCT GCACACCACC 1260

ATGCTGCGGG TCCATCCCAC CCTGGGGAGT GGAACTGCAG AGACAAGACC TCCAGAGAAT 1320

ACCCAGGCCC CAGCCTTCTT CTTGGAGCTA TTAAGCCTGA GCCGAGAGAA ACTTTGGGAC 1380

TCCGAGCTGC ATCCAGAAGA AAAAACTCCA GACTCTTACT TGGGGCTGGG ACCCCAAGAC 1440

CTGCTGGCAG CTAGCCTCAC TGCTGTCCTC CTGGGAGGGT GGATTCTCTT TGTGATGAGG 1500

CAGCAGCAGC CGCAGGTGGT GGAGAAGCAG CAGGAGACCC CCCTGGCATC TGCAGACTCT 1560

GCTCACATCT CCCAGGATGC CCAGTCCCTG CACTCGGGGG CCACCCGGAG GAGCCAGAAG 1620

AGGTTTCAGA GTCCCTCAAA GCAAGCCCAG CCACTCGACG ACCCTGAAGC TGAGCAACTC 1680

ACCGTAGTGG GGAAGATTTC CTTCAATCCC AAGGACGTGC TGGGCCGCGG GGCAGGCGGG 1740

ACTTTCGTTT TCCGGGGACA GTTTGAGGGA CGGGCAGTGG CTGTCAAGCG GCTCCTCCGC 1800

GAGTGCTTTG GCCTGGTTCG GCGGGAAGTT CAACTGCTGC AGGAGTCTGA CAGGCACCCC 1860

AACGTGCTCC GCTACTTCTG CACCGAGCGG GGACCCCAGT TCCACTACAT TGCCCTGGAG 1920

CTCTGCCGGG CCTCCTTGCA GGAGTACGTA GAAAACCCGG ACCTGGATCG CGGGGGTCTG 1980

GAGCCCGAGG TCGTGCTGCA GCAGCTGATG TCTGGCCTGG CCCACCTGCA CTCTTTACAC 2040

ATAGTGCACC GGGACCTGAA GCCAGGAAAT ATTCTCATCA CCGGGCCTGA CAGCCAGGGC 2100

CTGGGCAGAG TGGTGCTCTC AGACTTCGGC CTCTGCAAGA AGCTGCCTGC TGGCCGCTGT 2160

AGCTTCAGCC TCCACTCCGG CATCCCCGGC ACGGAAGGCT GGATGGCGCC CGAGCTTCTG 2220

CAGCTCCTGC CACCAGACAG TCCTACCAGT GCTGTGGACA TCTTCTCTGC AGGCTGCGTG 2280

TTCTACTACG TGCTTTCTGG TGGCAGCCAC CCCTTTGGAG ACAGTCTTTA TCGCCAGGCA 2340

AACATCCTCA CAGGGGCTCC CTGTCTGGCT CACCTGGAGG AAGAGGTCCA CGACAAAGTG 2400

GTTGCCCGGG ACCTGGTTGG AGCCATGTTG AGCCCGCTGC CGCAGCCACG CCCCTCTGCC 2460

CCCCAGGTGC TGGCCCACCC CTTCTTTTGG AGCAGAGCCA AGCAACTCCA GTTCTTCCAG 2520

GACGTCAGTG ACTGGCTGGA GAAGGAGTCC GAGCAGGAGC CCCTGGTGAG GGCACTGGAG 2580

GCGGGAGGCT GCGCAGTGGT CCGGGACAAC TGGCACAAGC ACATCTCCAT GCCGCTGCAG 2640

ACAGATCTGA GAAAGTTCCG GTCCTATAAG GGGACATCAG TGCGAGACCT GCTCCGTGCT 2700

GTGAGGAACA AGAAGCACCA CTACAGGGAG CTCCCAGTTG AGGTGCGACA GGCACTCGGC 2760

CAAGTCCCTG ATGGCTTTGT CCAGTACTTC ACAAACCGCT TCCCACGGCT GCTCCTCCAC 2820

ACGCACCGAG CCATGAGGAG CTGCGCCTCT GAGAGCCTCT TCCTGCCCTA CTACCCGCCA 2880

GACTCAGAGG CCAGGAGGCC ATGCCCTGGG GCTGCAGGGA GGTGA 2925

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+Ga+Gt+vfrG+fegr+vavkrll+e++ l++rev+ll+esd+hpnv+ryfc

Q: 568   FNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFC  627

         799*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+++qf+yialelc+aslq+yve++dl+ + +lep  +l+q++sGlahlhsl+ivhrdl

Q: 628   TERGPQFHYIALELCRASLQEYVENPDLD-RGGLEPEVVLQQLMSGLAHLHSLHIVHRDL  686

         *****************************.******************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp nili+ pd++g  rv++sdfGlckkl++G++sfs +sg++GteGw+apell+ l+++

Q: 687   KPGNILITGPDSQGLGRVVLSDFGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQLLPPD  746

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++tsavdifs+Gcvfyyvls+G+hpfGdsl+rqanil+g+ +l++l+ee +++v+a+dl+

Q: 747   SPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGAPCLAHLEEEVHDKVVARDLV  806

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

          +m++  p+ rpsa +vl+hp+f

Q: 807   GAMLSPLPQPRPSAPQVLAHPFF  829

         **********************9

Domain Sequence
(FASTA)

FNPKDVLGRG AGGTFVFRGQ FEGRAVAVKR LLRECFGLVR REVQLLQESD RHPNVLRYFC 60

TERGPQFHYI ALELCRASLQ EYVENPDLDR GGLEPEVVLQ QLMSGLAHLH SLHIVHRDLK 120

PGNILITGPD SQGLGRVVLS DFGLCKKLPA GRCSFSLHSG IPGTEGWMAP ELLQLLPPDS 180

PTSAVDIFSA GCVFYYVLSG GSHPFGDSLY RQANILTGAP CLAHLEEEVH DKVVARDLVG 240

AMLSPLPQPR PSAPQVLAHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

ptr:453992

;

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 4.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013