EKS-PAT-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	527.8	5.1E-159	24	291	268

Status

Unreviewed

Ensembl Protein

ENSPTRP00000061384

UniProt Accession

H2QAY4;

Protein Name

Protein Synonyms/Alias

Phosphorylase kinase, gamma 2 (Testis);

Gene Name

ENSG00000156873

Gene Synonyms/Alias

ENSG00000156873; PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000008014	ENSPTRP00000013693	ENSPTRT00000014784
ENSPTRG00000008014	ENSPTRP00000061384	ENSPTRT00000075757

Organism

Pan troglodytes

Functional Description

Protein Length

374

Protein Sequence
(FASTA)

MTLDVGPEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGHEF AVKIMEVTAE 60

RLSPEQLEEV REATRRETHI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT 120

EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDNMQIRLS DFGFSCHLEP 180

GEKLRELCGT PGYLAPEILK CSMDETHPGY GKEVDLWACG VILFTLLAGS PPFWHRRQIL 240

MLRMIMEGQY QFSSPEWDDR SSTVKDLISR LLQVDPEARL TAEQALQHPF FERCEGSQPW 300

NLTPRQRFRV AVWTVLAAGR VALSTHRVRP LTKNALLRDP YALRSVRRLI DNCAFRLYGH 360

WIRKQWIGKL MACV 374

Nucleotide Sequence
(FASTA)

ATGACGCTGG ACGTGGGGCC GGAGGATGAG CTGCCCGACT GGGCCGCCGC CAAAGAGTTT 60

TACCAGAAGT ACGACCCTAA GGACGTCATC GGCAGAGGAG TGAGCTCTGT GGTCCGCCGT 120

TGTGTTCATC GAGCTACTGG CCACGAGTTT GCGGTGAAGA TTATGGAAGT GACAGCTGAG 180

CGGCTGAGTC CTGAGCAGCT GGAGGAGGTG CGGGAAGCCA CACGGCGAGA GACACACATC 240

CTTCGCCAGG TCGCCGGCCA CCCCCACATC ATCACCCTCA TCGATTCGTA TGAGTCTTCT 300

AGCTTCATGT TCCTGGTGTT TGACCTGATG CGGAAGGGAG AGCTGTTTGA CTATCTCACA 360

GAGAAGGTGG CCCTCTCTGA AAAGGAAACC AGGTCCATCA TGCGGTCTCT GCTGGAAGCA 420

GTGAGCTTTC TCCATGCCAA CAACATTGTG CATCGAGATC TGAAGCCCGA GAATATTCTC 480

CTAGATGACA ATATGCAGAT CCGACTTTCA GATTTCGGGT TCTCCTGCCA CTTGGAACCT 540

GGCGAGAAGC TTCGAGAGTT GTGTGGGACC CCAGGGTATC TAGCGCCAGA GATCCTTAAA 600

TGCTCCATGG ATGAAACCCA CCCAGGCTAT GGCAAGGAGG TCGACCTCTG GGCCTGTGGG 660

GTGATCTTGT TTACACTCCT GGCTGGCTCG CCACCCTTCT GGCACCGGCG GCAGATCCTG 720

ATGTTACGCA TGATCATGGA GGGCCAGTAC CAGTTCAGTT CCCCCGAGTG GGATGACCGT 780

TCCAGCACTG TCAAAGACCT GATCTCCAGG CTGCTGCAGG TGGATCCTGA GGCACGCCTG 840

ACAGCTGAGC AGGCCCTACA GCACCCCTTC TTTGAGCGTT GTGAAGGCAG CCAACCCTGG 900

AACCTCACCC CCCGCCAGCG GTTCCGGGTG GCAGTGTGGA CGGTGCTGGC TGCTGGACGA 960

GTGGCCCTAA GCACCCATCG TGTACGGCCA CTGACCAAGA ATGCACTGTT GAGGGACCCT 1020

TATGCGCTGC GGTCAGTGCG GCGCCTCATC GACAACTGTG CCTTCCGGCT CTACGGGCAC 1080

TGGATAAGGA AGCAGTGGAT TGGAAAGCTG ATGGCTTGTG TATGA 1125

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pk+++GrGvssvvrrc+++atg+efavki++v+ae+ls+e+++e+reat++e++ilrq

Q: 24    YDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQ  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v+Ghp+ii+l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++

Q: 84    VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha+nivhrdlkpenillddn++i+lsdfGfs++le+GeklrelcGtpgylapeilkcsm

Q: 144   LHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++pGy+kevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++

Q: 204   DETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSST  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+ll+vdpe+rltae+al+hpff

Q: 264   VKDLISRLLQVDPEARLTAEQALQHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKDVIGRG VSSVVRRCVH RATGHEFAVK IMEVTAERLS PEQLEEVREA TRRETHILRQ 60

VAGHPHIITL IDSYESSSFM FLVFDLMRKG ELFDYLTEKV ALSEKETRSI MRSLLEAVSF 120

LHANNIVHRD LKPENILLDD NMQIRLSDFG FSCHLEPGEK LRELCGTPGY LAPEILKCSM 180

DETHPGYGKE VDLWACGVIL FTLLAGSPPF WHRRQILMLR MIMEGQYQFS SPEWDDRSST 240

VKDLISRLLQ VDPEARLTAE QALQHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

ptr:741602

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013