EPS-PAT-00117

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PAT-00117

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PDP	408.0	9.2E-123	226	441	216

Status

Unreviewed

Ensembl Protein

ENSPTRP00000014013

UniProt Accession

H2QBA2;

Protein Name

Protein Synonyms/Alias

Pyruvate dehyrogenase phosphatase catalytic subunit 2;

Gene Name

ENSG00000172840

Gene Synonyms/Alias

ENSG00000172840; PDP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000008204	ENSPTRP00000014013	ENSPTRT00000015130

Organism

Pan troglodytes

Functional Description

Protein Length

529

Protein Sequence
(FASTA)

MSSTVSYWIL NSTRNSIATL QGGRRLYSRY VSNRNKLKWR LFSRVPPTLN SSPCGGFTLC 60

KAYRHTSTEE DDFHLQLSPE QINEVLRAGE STHKILDLES RVPNSVLRFE SNQLAANSPV 120

EDRRGVASCL QTNGLMFGIF DGHGGHACAQ AVSERLFYYV AVSLMSHQTL EHMEGAMESM 180

KPLLPILHWL KHPGDSIYKD VTSVHLDHLR VYWQELLDLH MEMGLSIEEA LMYSFQRLDS 240

DISLEIQAPL EDEVTRNLSL QVAFSGATAC MAHVDGIHLH VANAGDCRAI LGVQEDNGMW 300

SCLPLTRDHN AWNQAELSRL KREHPESEDR TIIMEDRLLG VLIPCRAFGD VQLKWSKELQ 360

RSILERGFNT EALNIYQFTP PHYYTPPYLT AEPEVTYHRL RPQDKFLVLA SDGLWDMLSN 420

EDVVRLVVGH LAEADWHKTD LAQRPANLGL MQSLLLQRKA SGLHEADQNA ATRLIRHAIG 480

NNEYGEMEAE RLAAMLTLPE DLARMYRDDI TVTVVYFNSE SIGAYYKGG 529

Nucleotide Sequence
(FASTA)

ATGTCAAGTA CTGTGTCCTA CTGGATCTTA AATTCTACAA GGAACAGCAT TGCCACATTG 60

CAAGGGGGCA GACGCTTATA CTCCAGGTAT GTCTCAAATA GGAATAAATT AAAATGGAGG 120

CTCTTTTCCC GGGTGCCACC CACCCTAAAC AGTTCCCCAT GTGGTGGCTT TACTCTGTGC 180

AAAGCCTACA GACACACATC AACAGAGGAA GATGATTTTC ACTTGCAACT CAGCCCTGAG 240

CAGATAAATG AAGTGCTTCG AGCTGGCGAG TCAACCCACA AGATTCTTGA CCTTGAAAGC 300

AGAGTCCCAA ATTCAGTGTT GCGGTTTGAG AGCAACCAGC TGGCTGCCAA TTCCCCAGTG 360

GAGGACCGGC GAGGTGTAGC CTCCTGCCTG CAAACCAATG GACTGATGTT TGGCATCTTC 420

GATGGACATG GTGGTCATGC ATGTGCCCAA GCAGTGAGCG AGAGGCTCTT CTACTATGTG 480

GCAGTGTCCC TGATGTCCCA CCAGACCCTG GAGCACATGG AGGGAGCTAT GGAAAGCATG 540

AAACCCTTGC TGCCCATCCT GCATTGGCTC AAGCACCCAG GGGACAGCAT CTACAAGGAT 600

GTCACATCTG TGCATCTTGA CCACCTCCGT GTCTATTGGC AGGAACTGCT TGACTTGCAC 660

ATGGAAATGG GACTAAGCAT TGAAGAAGCA TTAATGTACT CCTTCCAGAG ACTGGATTCT 720

GACATCTCGC TGGAAATCCA GGCCCCCCTG GAAGATGAGG TGACAAGGAA CCTGTCACTC 780

CAGGTTGCTT TCTCTGGGGC AACAGCTTGC ATGGCCCATG TTGATGGAAT TCACTTGCAC 840

GTGGCAAATG CTGGTGACTG CCGAGCCATC CTTGGTGTCC AGGAGGACAA TGGCATGTGG 900

TCTTGTCTGC CCCTTACACG TGACCACAAT GCCTGGAACC AGGCCGAGCT GTCCCGGCTA 960

AAGAGGGAGC ACCCTGAGTC AGAGGACAGG ACGATCATCA TGGAGGACAG GCTGCTGGGC 1020

GTCCTCATCC CCTGCAGGGC CTTTGGGGAT GTTCAGCTGA AGTGGAGTAA AGAGTTGCAG 1080

CGCAGCATTC TGGAGAGGGG CTTCAATACC GAGGCCCTCA ACATTTACCA GTTCACACCC 1140

CCACACTACT ACACTCCACC CTACCTGACT GCTGAGCCTG AGGTCACATA CCACAGGCTG 1200

AGGCCCCAGG ATAAGTTCCT TGTGCTGGCC TCAGATGGCC TGTGGGACAT GCTGAGCAAT 1260

GAGGACGTGG TAAGGCTGGT GGTGGGGCAC CTGGCTGAGG CAGATTGGCA CAAGACAGAC 1320

TTGGCCCAGA GACCCGCCAA CTTGGGGCTC ATGCAGAGCC TGCTGCTGCA GAGGAAAGCC 1380

AGTGGGCTCC ACGAGGCTGA CCAAAATGCA GCCACGCGGC TGATCAGACA TGCCATCGGG 1440

AACAATGAGT ATGGGGAGAT GGAGGCAGAG CGGCTGGCGG CGATGCTGAC ATTGCCAGAG 1500

GACTTGGCGA GGATGTACAG GGATGATATC ACTGTCACTG TGGTGTATTT TAACTCAGAA 1560

TCGATCGGTG CATATTACAA GGGGGGTTAA 1590

Domain Profile

S: 4     dvkealvnafkrldedisleaqvsdedevlrylvlrvalsGataclahvdGvdlhvantG  63

          ++eal+++f+rld+disle+q++ edev+r+l+l+va+sGatac+ahvdG++lhvan+G

Q: 226   SIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAG  285

         699*********************************************************

S: 64    dsravlGvqeedgswsavklsrdhnaqneselerlkaehpkseaktvikedrllgllipl  123

         d+ra+lGvqe++g+ws+++l+rdhna+n++el+rlk+ehp+se++t+i+edrllg+lip+

Q: 286   DCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPC  345

         ************************************************************

S: 124   rafGdvkfkwskelqkrvvesgfdvladneykfiapnyytppyltaepevtyhrlrpqdk  183

         rafGdv++kwskelq++++e+gf+++a+n+y+f++p+yytppyltaepevtyhrlrpqdk

Q: 346   RAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDK  405

         ************************************************************

S: 184   flvlasdGlwdllsredvvrlvgeylaeadttltel  219

         flvlasdGlwd+ls+edvvrlv+++laead+++t+l

Q: 406   FLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDL  441

         **********************************96

Domain Sequence
(FASTA)

SIEEALMYSF QRLDSDISLE IQAPLEDEVT RNLSLQVAFS GATACMAHVD GIHLHVANAG 60

DCRAILGVQE DNGMWSCLPL TRDHNAWNQA ELSRLKREHP ESEDRTIIME DRLLGVLIPC 120

RAFGDVQLKW SKELQRSILE RGFNTEALNI YQFTPPHYYT PPYLTAEPEV TYHRLRPQDK 180

FLVLASDGLW DMLSNEDVVR LVVGHLAEAD WHKTDL 216

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Pyruvate; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>