EKS-PAT-00225

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00225

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	242.3	5.3E-72	139	307	169

Status

Unreviewed

Ensembl Protein

ENSPTRP00000017370

UniProt Accession

H2QEV7;

Protein Name

Protein Synonyms/Alias

Gene Name

MKNK2

Gene Synonyms/Alias

MKNK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000010220	ENSPTRP00000017370	ENSPTRT00000018769

Organism

Pan troglodytes

Functional Description

Protein Length

404

Protein Sequence
(FASTA)

MVQKKPAELQ GFHRSFKGQN PFELAFSLDQ PDHGDSDFGL QCSARPDTPA SQPIDIPDAK 60

KRGKKKKRGR ATDSFSGRFE DVYQLQEDVL GEGAHARVQT CINLITSQEY AVKIIEKQPG 120

HIRSRVFREV EMLYQCQGHI AHRDLKPENI LCEHPNQVSP VKICDFDLGS GIKLNGDCSP 180

ISTPELLTPC GSAEYMAPEV VEAFSEEASI YDKRCDLWSL GVILYILLSG YPPFVGRCGS 240

DCGWDRGEAC PACQNMLFES IQEGKYEFPD KDWAHISCAA KDLISKLLVR DAKQRLSAAQ 300

VLQHPWVQGC APENTLPTPM VLQRNSCAKD LTSFAAEAIA MNRQLAQHDE DLAEEEAAGQ 360

GQPVLVRATS RCLQLSPPSQ SKLAQRRQRA SLSSAPVVLV GDHA 404

Nucleotide Sequence
(FASTA)

ATGGTGCAGA AGAAACCAGC CGAACTTCAG GGTTTCCACC GTTCGTTCAA GGGGCAGAAC 60

CCCTTCGAGC TGGCCTTCTC CCTAGACCAG CCCGACCACG GAGACTCTGA CTTTGGCCTG 120

CAGTGCTCAG CCCGCCCTGA CACGCCCGCC AGCCAGCCCA TTGACATCCC GGACGCCAAG 180

AAGCGGGGCA AGAAGAAGAA GCGCGGCCGG GCCACCGACA GCTTCTCGGG CAGGTTTGAA 240

GACGTCTACC AGCTGCAGGA AGATGTGCTG GGGGAGGGCG CTCATGCCCG AGTGCAGACC 300

TGCATCAACC TGATCACCAG CCAGGAGTAC GCCGTCAAGA TCATTGAGAA GCAGCCAGGC 360

CACATTCGGA GTAGGGTTTT CAGGGAGGTG GAGATGCTGT ACCAGTGCCA GGGACACATC 420

GCCCACAGGG ACCTAAAGCC GGAAAACATC CTCTGTGAGC ACCCCAACCA GGTCTCCCCC 480

GTGAAGATCT GTGACTTCGA CCTGGGCAGC GGCATCAAAC TCAACGGGGA CTGCTCCCCT 540

ATCTCCACCC CGGAGCTGCT CACTCCGTGC GGCTCGGCGG AGTACATGGC CCCGGAGGTG 600

GTGGAGGCCT TCAGCGAGGA GGCTAGCATC TACGACAAGC GCTGCGACCT GTGGAGCCTG 660

GGCGTCATCT TGTATATCCT ACTCAGCGGC TACCCGCCCT TCGTGGGCCG CTGTGGCAGC 720

GACTGCGGCT GGGACCGCGG CGAGGCCTGC CCTGCCTGCC AGAACATGCT GTTTGAGAGC 780

ATCCAGGAGG GCAAGTACGA GTTCCCCGAC AAGGACTGGG CCCACATCTC CTGCGCTGCC 840

AAAGACCTCA TCTCCAAGCT GCTCGTCCGT GACGCCAAGC AGAGGCTGAG TGCCGCCCAA 900

GTCCTGCAGC ACCCCTGGGT TCAGGGGTGC GCCCCGGAGA ACACCTTGCC CACTCCCATG 960

GTCCTGCAGA GGAACAGCTG TGCCAAAGAC CTCACGTCCT TCGCGGCTGA GGCCATTGCC 1020

ATGAACCGGC AGCTGGCCCA GCACGACGAG GACCTGGCTG AGGAGGAGGC CGCGGGGCAG 1080

GGCCAGCCCG TCCTGGTCCG AGCTACCTCA CGCTGCCTGC AGCTGTCTCC ACCCTCCCAG 1140

TCCAAGCTGG CGCAGCGGCG GCAAAGGGCC AGCCTGTCCT CGGCCCCCGT GGTCCTGGTG 1200

GGAGACCACG CCTGA 1215

Domain Profile

S: 116   niahrDlkpenlLyeskeknapvklcDfglaketeee........eelktpcltaeyvaP  167

          iahrDlkpen+L+e++++++pvk+cDf+l+++++ +        +el tpc++aey+aP

Q: 139   HIAHRDLKPENILCEHPNQVSPVKICDFDLGSGIKLNgdcspistPELLTPCGSAEYMAP  198

         69*******************************955556899999***************

S: 168   evleaekeeallydksCDlWslGvilyillcGypPfyskkg...........raiskklk  216

         ev+ea++eea++ydk+CDlWslGvilyill+GypPf++++g            a++++l+

Q: 199   EVVEAFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGRCGsdcgwdrgeacPACQNMLF  258

         ****************************************99*********99*******

S: 217   eriqegkyefPeeeWsevseeakdlirklLkrdpkerltieevlnhpwv  265

         e+iqegkyefP+++W+++s +akdli+klL+rd+k+rl++++vl+hpwv

Q: 259   ESIQEGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWV  307

         ************************************************8

Domain Sequence
(FASTA)

HIAHRDLKPE NILCEHPNQV SPVKICDFDL GSGIKLNGDC SPISTPELLT PCGSAEYMAP 60

EVVEAFSEEA SIYDKRCDLW SLGVILYILL SGYPPFVGRC GSDCGWDRGE ACPACQNMLF 120

ESIQEGKYEF PDKDWAHISC AAKDLISKLL VRDAKQRLSA AQVLQHPWV 169

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>