EKS-PAT-00390

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00390

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	481.9	4.1E-145	13	275	263

Status

Unreviewed

Ensembl Protein

ENSPTRP00000017483

UniProt Accession

G2HGB3;

Protein Name

Protein Synonyms/Alias

Death-associated protein kinase 3;

Gene Name

DAPK3

Gene Synonyms/Alias

DAPK3; ENSG00000167657;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000010286	ENSPTRP00000017483	ENSPTRT00000018891

Organism

Pan troglodytes

Functional Description

Protein Length

454

Protein Sequence
(FASTA)

MSTFRQEDVE DHYEMGEELG SGQFAIVRKC RQKGTGKEYA AKFIKKRRLS SSRRGVSREE 60

IEREVNILRE IRHPNIITLH DIFENKTDVV LILELVSGGE LFDFLAEKES LTEDEATQFL 120

KQILDGVHYL HSKRIAHFDL KPENIMLLDK NVPNPRIKLI DFGIAHKIEA GNEFKNIFGT 180

PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY 240

FSNTSELAKD FIRRLLVKDP KRRMTIAQSL EHSWIKAIRR RNVRGEDSGR KPERRRLKTT 300

RLKEYTIKSH SSLPPNNSYA DFERFSKVLE EAAAAEEGLR ELQRSRRLCH EDVEALAAIY 360

EEKEAWYREE SDSLGQDLRR LRQELLKTEA LKRQAQEEAK GALLGTSGLK RRFSRLENRY 420

EALAKQVASE MRFVQDLVRA LEQEKLQGVE CGLR 454

Nucleotide Sequence
(FASTA)

ATGTCCACGT TCAGGCAGGA GGACGTGGAG GACCATTATG AGATGGGGGA GGAGCTGGGC 60

AGCGGCCAGT TTGCCATCGT GCGGAAGTGC CGGCAGAAGG GCACGGGCAA GGAGTACGCA 120

GCCAAGTTCA TCAAGAAGCG CCGCCTGTCA TCCAGCCGGC GTGGGGTGAG CCGGGAGGAG 180

ATCGAGCGGG AGGTGAACAT CCTGCGGGAG ATCCGGCACC CCAACATCAT CACCCTGCAC 240

GACATCTTCG AGAACAAGAC GGACGTGGTC CTCATCCTGG AGCTGGTCTC TGGCGGGGAG 300

CTCTTTGACT TCCTGGCGGA GAAGGAGTCG CTGACGGAGG ACGAGGCCAC CCAGTTCCTC 360

AAGCAGATCC TGGACGGCGT TCACTACCTG CATTCTAAGC GCATCGCACA CTTTGACCTG 420

AAGCCGGAAA ACATCATGCT GCTGGACAAG AACGTGCCCA ACCCACGAAT CAAGCTCATC 480

GACTTCGGCA TCGCGCACAA GATCGAGGCG GGGAACGAGT TCAAGAACAT CTTTGGCACC 540

CCGGAGTTTG TGGCCCCAGA GATTGTGAAC TATGAGCCGC TGGGCCTGGA GGCGGACATG 600

TGGAGCATCG GTGTCATCAC CTACATCCTC CTGAGCGGTG CATCCCCGTT CCTGGGCGAG 660

ACCAAGCAGG AGACGCTCAC CAACATCTCA GCCGTGAACT ACGACTTCGA CGAGGAGTAC 720

TTCAGCAACA CCAGCGAGCT GGCCAAGGAC TTCATTCGCC GGCTGCTCGT CAAAGATCCC 780

AAACGGAGAA TGACCATTGC CCAGAGCCTG GAACATTCCT GGATTAAGGC GATCCGGCGG 840

CGGAACGTGC GTGGTGAGGA CAGCGGCCGC AAGCCCGAGC GGCGGCGCCT GAAGACCACG 900

CGTCTGAAGG AGTACACCAT CAAGTCGCAC TCCAGCTTGC CGCCCAACAA CAGCTACGCC 960

GACTTCGAGC GCTTCTCCAA GGTGCTGGAG GAGGCGGCGG CCGCCGAGGA GGGCCTGCGC 1020

GAGCTGCAGC GCAGCCGGCG GCTCTGCCAC GAGGACGTGG AGGCGCTGGC CGCCATCTAC 1080

GAGGAGAAGG AGGCCTGGTA CCGCGAGGAG AGCGACAGCC TGGGCCAGGA CCTGCGGAGG 1140

CTACGGCAGG AGCTGCTCAA GACCGAGGCG CTCAAGCGGC AGGCGCAGGA GGAGGCCAAG 1200

GGCGCGCTGC TGGGGACCAG CGGCCTCAAG CGCCGCTTCA GCCGCCTGGA GAACCGCTAC 1260

GAGGCGCTGG CCAAGCAAGT AGCCTCCGAG ATGCGCTTCG TGCAGGACCT CGTGCGCGCC 1320

CTGGAGCAGG AGAAGCTGCA GGGCGTGGAG TGCGGGCTGC GCTAG 1365

Domain Profile

S: 1     letgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeir  60

         +e+g+elgsG+fa+vrkcr+k tGkeyaakf+kkrrl+ssrrgvsreeierev++l+eir

Q: 13    YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR  72

         5789********************************************************

S: 61    sepnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylh  120

          +pn+i+lh+++enk+dv+lilelv+GGelfd+laekesl+e+eat++lkqil+gv+ylh

Q: 73    -HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH  131

         .***********************************************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         sk+i+h+dlkPeni+lldk+vp+++iklidfG+++kie+g+e+k+i+GtPefvaPeivny

Q: 132   SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNY  191

         ************************************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         epl+le+dmwsiGvityillsgasPflG+tkqetl+nisavn+df+ee+fs++selakdf

Q: 192   EPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDF  251

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         irrllvkdp++r+ti+++lehsw+

Q: 252   IRRLLVKDPKRRMTIAQSLEHSWI  275

         ***********************8

Domain Sequence
(FASTA)

YEMGEELGSG QFAIVRKCRQ KGTGKEYAAK FIKKRRLSSS RRGVSREEIE REVNILREIR 60

HPNIITLHDI FENKTDVVLI LELVSGGELF DFLAEKESLT EDEATQFLKQ ILDGVHYLHS 120

KRIAHFDLKP ENIMLLDKNV PNPRIKLIDF GIAHKIEAGN EFKNIFGTPE FVAPEIVNYE 180

PLGLEADMWS IGVITYILLS GASPFLGETK QETLTNISAV NYDFDEEYFS NTSELAKDFI 240

RRLLVKDPKR RMTIAQSLEH SWI 263

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:455594

;

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013