EKS-PAT-00040

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00040

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	383.2	5.4E-115	166	432	267

Status

Unreviewed

Ensembl Protein

ENSPTRP00000019459

UniProt Accession

H2QGX3;

Protein Name

Protein Synonyms/Alias

Vaccinia related kinase 3;

Gene Name

ENSG00000105053

Gene Synonyms/Alias

ENSG00000105053; VRK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000011330	ENSPTRP00000019459	ENSPTRT00000021074

Organism

Pan troglodytes

Functional Description

Protein Length

474

Protein Sequence
(FASTA)

MISFCPDCGK SIQAAFKFCP YCGNSLPVEE HVGSQTFVSP RVSSFQGSKR GLNSSFEISP 60

KKVKWSSTVT SPRLSLFSDG DSSESEDPLS SSERSKGSGS RPPTPKSSPQ KTRKSPQVTR 120

GSPQKTSCSP QKTRQSPQTL KRSRVTTSLE ALPTGTVLTD KSGQQWELKS LQTRDNQGIL 180

YEAAPTSALT CDSGPQKQKF SLKLDAKDGR LFNEQNFFQR AAKPLQVNKW KKLYSTPLLA 240

IPTCMGFGVH QDKYRFLVLP SLGRSLQSAL DVSPKHVLSE RSVLQVACRL LDALEFLHEN 300

EYVHGNVTAE NIFVDPEDRS QVTLAGYGFA FRYCPSGKHV AYVEGSRSPH EGDLEFISMD 360

LHKGCGPSRR SDLQSLGYCM LKWLYGFLPW TNCLPNTEDI MKQKQKFVDK PGPFVGPCGH 420

WIRPSETLQK YLKVVMALTY EEKPPYAMLR NTLEALLQDL RVSPYDPIGL PMVP 474

Nucleotide Sequence
(FASTA)

ATGATCTCCT TCTGTCCAGA CTGTGGCAAA AGTATCCAAG CAGCATTCAA ATTCTGCCCC 60

TACTGTGGAA ATTCTTTGCC TGTAGAGGAG CATGTAGGGT CCCAGACCTT TGTCAGTCCA 120

CGTGTGTCAT CCTTCCAAGG CTCAAAGAGA GGGCTGAACT CCAGTTTTGA AATCTCTCCT 180

AAGAAAGTGA AATGGTCCAG CACCGTCACC TCTCCCCGAT TATCCCTCTT CTCAGATGGT 240

GACAGTTCTG AGTCTGAAGA TCCTCTGAGT TCCTCTGAGA GATCCAAAGG CTCCGGGAGC 300

AGACCCCCAA CCCCCAAAAG CAGCCCTCAG AAGACCAGGA AGAGCCCTCA GGTGACCAGG 360

GGTAGCCCTC AGAAGACCAG CTGCAGCCCT CAGAAGACCA GACAGAGCCC TCAGACGCTG 420

AAGCGGAGCC GAGTGACCAC CTCACTTGAA GCTTTGCCCA CAGGGACAGT GCTGACAGAC 480

AAGAGTGGGC AACAGTGGGA GCTGAAGTCC CTCCAGACCA GGGACAACCA GGGCATTCTC 540

TATGAAGCTG CACCCACCTC CGCCCTCACC TGTGACTCAG GACCACAGAA GCAAAAGTTC 600

TCGCTCAAAC TGGATGCCAA GGATGGGCGC TTGTTCAATG AGCAGAACTT CTTCCAGCGG 660

GCCGCCAAGC CTCTGCAAGT CAACAAGTGG AAGAAGCTGT ACTCGACCCC ACTGCTGGCC 720

ATCCCTACCT GCATGGGTTT CGGTGTTCAC CAGGACAAAT ACAGGTTCTT GGTGTTACCC 780

AGCCTGGGGA GGAGCCTTCA GTCGGCCCTG GATGTCAGCC CAAAGCATGT GCTGTCAGAG 840

AGGTCTGTGC TGCAGGTGGC CTGCCGGCTG CTGGATGCCC TGGAGTTCCT CCATGAGAAT 900

GAGTATGTTC ATGGAAATGT GACAGCTGAA AATATCTTTG TGGATCCAGA GGACCGGAGT 960

CAGGTGACTT TGGCAGGCTA TGGCTTCGCC TTCCGCTATT GCCCAAGTGG CAAACACGTG 1020

GCCTACGTGG AAGGCAGCAG GAGCCCTCAT GAGGGGGACC TTGAGTTCAT TAGCATGGAC 1080

CTGCACAAGG GATGCGGGCC CTCCCGCCGC AGCGACCTCC AGAGCCTGGG CTACTGCATG 1140

CTGAAGTGGC TCTACGGGTT TCTGCCATGG ACAAATTGCC TTCCCAACAC TGAGGACATC 1200

ATGAAGCAAA AACAGAAGTT TGTTGATAAG CCGGGGCCCT TTGTGGGACC CTGCGGTCAC 1260

TGGATCAGGC CCTCAGAGAC CCTGCAGAAG TACCTGAAGG TGGTGATGGC CCTCACGTAT 1320

GAGGAGAAGC CGCCCTACGC CATGCTGAGG AACACCCTAG AAGCTTTGCT GCAGGATCTG 1380

CGTGTGTCTC CATATGACCC CATTGGCCTC CCGATGGTGC CCTAG 1425

Domain Profile

S: 1     wklgkkigkggfGeiyla.....ltckkeekdaklvvkvepkenGpLfvelkfyqraakk  55

         w+l++ ++++++G++y+a     ltc+++++++k+++k+++k+ G+Lf+e++f+qraak+

Q: 166   WELKSLQTRDNQGILYEAaptsaLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAAKP  224

         99***************9999999******************9.****************

S: 56    eqikkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkr.lsek  114

          q++kwkk ++++ll+iPt++++G+h+   +kyRflvlp+lgr+Lq++l+ ++k+ lse+

Q: 225   LQVNKWKKLYSTPLLAIPTCMGFGVHQ---DKYRFLVLPSLGRSLQSALDVSPKHvLSER  281

         ***************************...*************************99***

S: 115   tvlqlavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhke  174

         +vlq+a+rlld+le+lHeneYvHg+++A+n+++++e+ sqv+L++yG+a+rycp+gkh++

Q: 282   SVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDRSQVTLAGYGFAFRYCPSGKHVA  341

         ************************************************************

S: 175   ykedkrraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvq  234

         y+e++r++H+G+lef+s+D+HkG++psrRsDl++LgYc+lkWl+g+LPW+++l+++e+++

Q: 342   YVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIM  401

         ************************************************************

S: 235   kakekfldelpellkkllkkkssseelakyl  265

         k+k+kf+d+++ ++  + ++ ++se+l+kyl

Q: 402   KQKQKFVDKPGPFVGPCGHWIRPSETLQKYL  432

         ******************************8

Domain Sequence
(FASTA)

WELKSLQTRD NQGILYEAAP TSALTCDSGP QKQKFSLKLD AKDGRLFNEQ NFFQRAAKPL 60

QVNKWKKLYS TPLLAIPTCM GFGVHQDKYR FLVLPSLGRS LQSALDVSPK HVLSERSVLQ 120

VACRLLDALE FLHENEYVHG NVTAENIFVD PEDRSQVTLA GYGFAFRYCP SGKHVAYVEG 180

SRSPHEGDLE FISMDLHKGC GPSRRSDLQS LGYCMLKWLY GFLPWTNCLP NTEDIMKQKQ 240

KFVDKPGPFV GPCGHWIRPS ETLQKYL 267

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>