EKS-PAT-00276

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00276

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	387.0	3.5E-116	788	1053	266

Status

Unreviewed

Ensembl Protein

ENSPTRP00000021142

UniProt Accession

H2QIJ3;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000169679

Gene Synonyms/Alias

ENSG00000169679;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000012348	ENSPTRP00000021142	ENSPTRT00000022916

Organism

Pan troglodytes

Functional Description

Protein Length

1085

Protein Sequence
(FASTA)

MDTPENVLQM LEAHMQSYKG NDPLGEWERY IQWVEENFPE NKEYLITLLE HLMKEFLDKK 60

KYHNDPRFIS YCLKFAEYNS DLHQFFEFLY NHGIGTLSSP LYIAWAGHLE TQGELQHASA 120

VLQRGIQNQA EPREFLQQQY RLFQTRLTET HLPAQARTSE PLHNVQVLNQ MITSKSNPGN 180

NMACISKNQG SELSGVISSA CDKESNMEER VITISKSEYS VHSSLASKVD VEQVVMYCKE 240

KLIRGESEFS FEELRAQKYN QRRKHEQWVN EDRHYMKRKE ANAFEEQLLK QKMDELHKKL 300

HQVVETSHED LPASQERSEV NPARMGPSVG SQQELRAPCL PVTYQQTPVN MEKNPREAPP 360

VVPPLANAIS AALVSPATSQ SIAPPVPLKA QTVTDSMFAV ASKDAGCVNK STHEFKPQSG 420

AEIKEGCETH KVANTSSFHT TPNTSLGMVQ ATPSKVQPSP TVHTKEALGF IMNMFQAPTL 480

PDISDDKDEW QSLDQNEDAF EAQFQKNVRS SGAWGVNKII SSLSSAFHVF EDGNKENYGL 540

PQPKNKPTGA RTFGERSVSR LPSKPKEEVP HAEEFLDDST VWGIRCNKTL APSPKSPGDF 600

TSAAQLASTP FHKLPAESVH ILEDKENVVA KQCTQATLDS CEENMVVPSR DGKFSPIQEK 660

SPEQALLSHM YSASLLHLSQ PAAGGVLTCE AELGVDACRL TDTDAAIAED PPDAIAGLQA 720

EWMQMSSLGT ADAPNFIVGN PWDDKLIFKL LSGLSKPVSS YPNTFEWQCK LPAIKPKTEF 780

QLGSKLVYVH HLLGEGAFAQ VYEATQGDLN DAKNKQKFVL KVQKPANPWE FYIGTQLMER 840

LKPSMQHMFM KFYSAHLFQN GSVLVGELYS YGTLLNAINL YKNTPEKVMP QGLVISFAMR 900

MLYMIEQVHD CEIIHGDIKP DNFILGNGFL EQDDEDDLSA GLALIDLGQS IDMKLFPKGT 960

IFTAKCETSG FQCVEMLSNK PWNYQIDYFG VAATVYCMLF GTYMKVKNEG GECKPEGLFR 1020

RLPHLDMWNE FFHVMLNIPD CHHLPSLDLL RQKLKKVFQQ HYPNKIRALR NRLIVLLLEC 1080

KRSRK 1085

Nucleotide Sequence
(FASTA)

ATGGACACCC CGGAAAATGT CCTTCAGATG CTTGAAGCCC ACATGCAGAG CTACAAGGGC 60

AATGACCCTC TTGGTGAATG GGAAAGATAC ATACAGTGGG TAGAAGAGAA TTTTCCTGAG 120

AATAAAGAAT ACTTGATAAC TTTACTAGAA CATTTAATGA AGGAATTTTT AGATAAGAAG 180

AAATACCACA ATGACCCAAG ATTCATCAGT TATTGTTTAA AATTTGCTGA GTACAACAGT 240

GACCTCCATC AATTTTTTGA GTTTCTGTAC AACCATGGGA TTGGAACCCT GTCATCCCCT 300

CTGTACATTG CCTGGGCGGG GCATCTGGAA ACCCAAGGAG AGCTGCAGCA TGCCAGTGCT 360

GTCCTTCAGA GAGGAATTCA AAACCAGGCT GAACCCAGAG AGTTCCTGCA ACAACAATAC 420

AGGTTATTTC AGACACGCCT CACTGAAACC CATTTGCCAG CTCAAGCTAG AACCTCAGAA 480

CCTCTGCATA ATGTTCAGGT TTTAAATCAA ATGATAACAT CAAAATCAAA TCCAGGAAAT 540

AACATGGCCT GCATTTCTAA GAATCAGGGT TCAGAGCTTT CTGGAGTGAT ATCTTCAGCT 600

TGTGATAAAG AGTCAAATAT GGAAGAAAGA GTGATCACGA TTTCTAAATC AGAATATTCT 660

GTGCACTCAT CTTTGGCATC CAAAGTTGAT GTTGAGCAGG TTGTTATGTA TTGCAAGGAG 720

AAGCTTATTC GTGGGGAATC AGAATTTTCC TTTGAAGAAT TGAGAGCCCA GAAATACAAT 780

CAACGGAGAA AGCATGAGCA ATGGGTAAAT GAAGACAGAC ATTATATGAA AAGGAAAGAA 840

GCAAATGCTT TTGAAGAACA GCTATTAAAA CAGAAAATGG ATGAACTTCA TAAGAAGTTG 900

CATCAGGTGG TGGAGACATC CCATGAGGAT CTGCCCGCTT CCCAGGAAAG GTCCGAGGTT 960

AATCCAGCAC GTATGGGGCC AAGTGTAGGC TCCCAGCAGG AACTGAGAGC GCCATGTCTT 1020

CCAGTCACCT ATCAGCAGAC ACCAGTGAAC ATGGAAAAGA ACCCAAGAGA GGCACCTCCT 1080

GTTGTTCCTC CTTTGGCAAA TGCTATTTCT GCAGCTTTGG TGTCCCCAGC CACCAGCCAG 1140

AGCATTGCTC CTCCTGTTCC TTTGAAAGCC CAGACAGTAA CAGACTCCAT GTTTGCAGTG 1200

GCCAGCAAAG ATGCTGGATG TGTGAATAAG AGTACTCATG AATTCAAGCC ACAGAGTGGA 1260

GCAGAGATCA AAGAAGGGTG TGAAACACAT AAGGTTGCCA ACACAAGTTC TTTTCACACA 1320

ACTCCAAACA CATCACTGGG AATGGTTCAG GCAACGCCAT CCAAAGTGCA GCCATCACCC 1380

ACCGTGCACA CAAAAGAAGC ATTAGGTTTC ATCATGAATA TGTTTCAGGC TCCTACACTT 1440

CCTGATATTT CTGATGACAA AGATGAATGG CAATCTCTAG ATCAAAATGA AGATGCATTT 1500

GAAGCCCAGT TTCAAAAAAA TGTAAGGTCA TCTGGGGCTT GGGGAGTCAA TAAGATCATC 1560

TCTTCTTTGT CATCTGCTTT TCATGTGTTT GAAGATGGAA ACAAAGAAAA TTATGGATTA 1620

CCACAGCCTA AAAATAAACC CACAGGAGCC AGGACCTTTG GAGAACGCTC TGTCAGCAGA 1680

CTTCCTTCAA AACCAAAGGA GGAAGTGCCT CATGCTGAAG AGTTTTTGGA TGACTCAACT 1740

GTATGGGGTA TTCGCTGCAA CAAAACCCTG GCACCCAGTC CTAAGAGCCC AGGAGACTTC 1800

ACATCTGCTG CACAACTTGC GTCTACACCA TTCCACAAGC TTCCAGCGGA GTCAGTGCAC 1860

ATTTTAGAAG ATAAAGAAAA TGTGGTAGCA AAACAGTGTA CCCAGGCGAC TTTGGATTCT 1920

TGTGAAGAAA ACATGGTGGT GCCTTCAAGG GATGGAAAAT TCAGTCCAAT TCAAGAGAAA 1980

AGCCCAGAAC AGGCCTTGTT GTCTCACATG TATTCAGCAT CCTTACTTCA TCTGAGCCAG 2040

CCTGCTGCAG GTGGGGTACT TACCTGTGAG GCAGAGTTGG GCGTTGATGC TTGCAGACTC 2100

ACAGACACTG ATGCTGCCAT TGCAGAAGAT CCACCAGATG CTATTGCTGG GCTCCAAGCA 2160

GAATGGATGC AGATGAGTTC ACTTGGGACT GCTGATGCTC CAAACTTCAT TGTTGGGAAC 2220

CCATGGGATG ATAAGCTGAT TTTCAAACTT TTATCTGGGC TTTCTAAACC AGTGAGTTCC 2280

TATCCAAATA CTTTTGAATG GCAATGTAAA CTTCCAGCCA TCAAGCCCAA GACTGAATTT 2340

CAATTGGGTT CTAAGCTGGT CTATGTCCAT CACCTTCTTG GAGAAGGAGC CTTTGCCCAG 2400

GTGTACGAAG CTACCCAGGG AGATCTGAAT GATGCTAAAA ATAAACAGAA ATTTGTTTTA 2460

AAGGTCCAAA AGCCTGCCAA CCCCTGGGAA TTCTACATTG GGACCCAGTT GATGGAAAGA 2520

CTAAAGCCAT CTATGCAGCA CATGTTTATG AAGTTCTATT CTGCCCACTT ATTCCAGAAT 2580

GGCAGTGTAT TAGTAGGAGA GCTCTACAGC TATGGAACAT TATTAAATGC CATTAACCTC 2640

TATAAAAATA CCCCTGAAAA AGTGATGCCT CAAGGTCTTG TCATCTCTTT TGCTATGAGA 2700

ATGCTTTACA TGATTGAGCA AGTGCATGAC TGTGAAATCA TTCATGGAGA CATTAAACCA 2760

GACAATTTCA TACTTGGAAA CGGATTTTTG GAACAGGATG ATGAAGATGA TTTATCTGCT 2820

GGCTTGGCAC TGATTGACCT GGGTCAGAGT ATAGATATGA AACTTTTTCC AAAAGGAACT 2880

ATATTCACAG CAAAGTGTGA AACATCTGGT TTTCAGTGTG TTGAGATGCT CAGCAACAAA 2940

CCATGGAACT ACCAGATCGA TTACTTTGGG GTTGCTGCAA CAGTATATTG CATGCTCTTT 3000

GGCACTTACA TGAAAGTGAA AAATGAAGGA GGAGAGTGTA AGCCTGAAGG TCTTTTTAGA 3060

AGGCTTCCTC ATTTGGATAT GTGGAATGAA TTTTTTCATG TTATGTTGAA TATTCCAGAT 3120

TGTCATCATC TTCCATCTTT GGATTTGTTA AGGCAAAAGC TGAAGAAGGT ATTTCAACAA 3180

CACTATCCTA ACAAGATTAG GGCCCTACGT AATAGGCTAA TTGTACTGCT CTTAGAATGT 3240

AAGCGTTCAC GAAAATAA 3258

Domain Profile

S: 2     eiekeigeGayakvykaeh....dsksgelvalKvekpansWefYIclqlkeRlkeeell  57

         ++++++geGa+a+vy+a++    d+k++++++lKv+kpan+WefYI +ql+eRlk ++++

Q: 788   YVHHLLGEGAFAQVYEATQgdlnDAKNKQKFVLKVQKPANPWEFYIGTQLMERLK-PSMQ  846

         79******************9999*******************************.77**

S: 58    ksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvllivqllkive  117

         +++++++sa+lfq++s+lv e++sygtll++in++k++ +kvm++ lv+++++++l+++e

Q: 847   HMFMKFYSAHLFQNGSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIE  906

         ************************************************************

S: 118   klHeveIiHgDlkPdnfllgnrimdkadkdkeekglkliDfgrsiDmkllpdgtkfkgka  177

         ++H++eIiHgD+kPdnf+lgn + ++ d+d+ ++gl+liD+g+siDmkl+p+gt f++k+

Q: 907   QVHDCEIIHGDIKPDNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKC  966

         ************************************************************

S: 178   ktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswklkqkikrllkke  237

         +t++f+c+eml++k+w+Yq+D+fg+aa+++++lfg+y++v++egg++k++  ++rl++ +

Q: 967   ETSGFQCVEMLSNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLD  1026

         ************************************************************

S: 238   lwekiferlLNisdastlpsleelveek  265

         +w+++f+++LNi+d+++lpsl+ l++ k

Q: 1027  MWNEFFHVMLNIPDCHHLPSLDLLRQ-K  1053

         ************************95.4

Domain Sequence
(FASTA)

YVHHLLGEGA FAQVYEATQG DLNDAKNKQK FVLKVQKPAN PWEFYIGTQL MERLKPSMQH 60

MFMKFYSAHL FQNGSVLVGE LYSYGTLLNA INLYKNTPEK VMPQGLVISF AMRMLYMIEQ 120

VHDCEIIHGD IKPDNFILGN GFLEQDDEDD LSAGLALIDL GQSIDMKLFP KGTIFTAKCE 180

TSGFQCVEML SNKPWNYQID YFGVAATVYC MLFGTYMKVK NEGGECKPEG LFRRLPHLDM 240

WNEFFHVMLN IPDCHHLPSL DLLRQK 266

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:459484

;

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311	; Mad3_BUB1_I; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489	; BUB1_N; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013