EKS-PAT-00421

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00421

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PDHK	225.6	1.5E-67	268	392	125

Status

Unreviewed

Ensembl Protein

ENSPTRP00000021603

UniProt Accession

H2QIZ6;

Protein Name

Protein Synonyms/Alias

Pyruvate dehydrogenase kinase, isozyme 1;

Gene Name

ENSG00000152256

Gene Synonyms/Alias

ENSG00000152256; PDK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000012642	ENSPTRP00000021603	ENSPTRT00000023424

Organism

Pan troglodytes

Functional Description

Protein Length

436

Protein Sequence
(FASTA)

MRLARLLRGA AFAGPGPGLR AAGSSRSFSS DSGSSPASER GVPGQVDFYA RFSPSPLSMK 60

QFLDFGSVNA CEKTSFMFLR QELPVRLANI MKEISLLPDN LLRTPSVQLV QSWYIQSLQE 120

LLDFKDKSAE DAKAIYDFTD TVIRIRNRHN DVIPTMAQGV IEYKESFGVD PVTSQNVQYF 180

LDRFYMSRIS IRMLLNQHSL LFGGKGKGSP SHRKHIGSIN PNCNVVEVIK DGYENARRLC 240

DLYYINSPEL ELEELNAKSP GQPIQVVYVP SHLYHMVFEL FKNAMRATME HHANRGVYPP 300

IQVHVTLGNE DLTVKMSDRG GGVPLRKIDR LFNYMYSTAP RPRVETSRAV PLAGFGYGLP 360

ISRLYAQYFQ GDLKLYSLEG YGTDAVIYIK ALSTDSIERL PVYNKAAWKH YNTNHEADDW 420

CVPSREPKDM TTFRSA 436

Nucleotide Sequence
(FASTA)

ATGAGGCTGG CGCGGCTGCT TCGCGGAGCC GCCTTTGCCG GCCCGGGCCC GGGGCTGCGC 60

GCCGCCGGCT CCAGCCGCAG CTTCAGCTCG GACTCGGGCT CCAGCCCGGC GTCCGAGCGC 120

GGCGTTCCGG GCCAGGTGGA CTTCTACGCG CGCTTCTCGC CGTCCCCGCT CTCCATGAAG 180

CAGTTCCTGG ACTTCGGATC AGTGAATGCT TGTGAAAAGA CCTCATTTAT GTTTCTGCGG 240

CAAGAGTTGC CTGTCAGACT GGCAAATATA ATGAAAGAAA TAAGTCTCCT TCCAGATAAT 300

CTTCTCAGGA CACCATCCGT TCAATTGGTA CAAAGCTGGT ATATCCAGAG TCTTCAGGAG 360

CTTCTTGATT TTAAGGACAA AAGTGCTGAG GATGCTAAAG CTATTTATGA CTTTACAGAT 420

ACTGTGATAC GGATCAGAAA CCGACACAAT GATGTCATTC CCACAATGGC CCAGGGTGTG 480

ATTGAATACA AGGAGAGCTT TGGGGTGGAT CCTGTCACCA GCCAGAATGT TCAGTACTTT 540

TTGGATCGAT TCTACATGAG TCGCATTTCA ATTAGAATGT TACTCAATCA GCACTCTTTA 600

TTGTTTGGTG GAAAAGGCAA AGGAAGTCCA TCTCATCGAA AACACATTGG AAGCATAAAT 660

CCAAACTGCA ATGTAGTTGA AGTTATTAAA GATGGCTATG AAAATGCTAG GCGTCTGTGT 720

GATTTGTATT ATATTAACTC TCCCGAACTA GAACTTGAAG AACTAAATGC AAAATCACCA 780

GGACAGCCAA TACAAGTGGT TTATGTACCA TCCCATCTCT ATCACATGGT GTTTGAACTT 840

TTCAAGAATG CAATGAGAGC CACTATGGAA CACCATGCCA ACAGAGGTGT TTACCCCCCT 900

ATTCAAGTTC ATGTTACGCT GGGTAATGAG GATTTGACTG TGAAGATGAG TGACCGAGGA 960

GGTGGCGTTC CTTTGAGGAA AATTGACAGA CTTTTCAACT ACATGTATTC AACTGCACCA 1020

AGACCTCGTG TTGAGACCTC CCGCGCGGTG CCTCTGGCTG GTTTTGGTTA TGGATTGCCC 1080

ATATCACGTC TTTACGCACA ATACTTCCAA GGAGACCTGA AGCTGTATTC CCTAGAGGGT 1140

TACGGGACAG ATGCAGTTAT CTACATTAAG GCTCTGTCAA CAGACTCAAT AGAAAGACTC 1200

CCAGTGTATA ACAAAGCTGC CTGGAAGCAT TACAACACCA ACCACGAGGC TGATGACTGG 1260

TGCGTCCCCA GCAGAGAACC CAAAGACATG ACGACGTTCC GCAGTGCCTA G 1311

Domain Profile

S: 1     yvpshlyyllfellknamratveshedkkvlpdvkvlvalgkedliikisdrGGGvplrk  60

         yvpshly+++fel+knamrat+e+h+++ v+p+++v+v+lg+edl++k+sdrGGGvplrk

Q: 268   YVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRK  327

         9***********************************************************

S: 61    idrlldymystapapskddaraaplaGfGyGlpisrlyakylqGdlkllsleGiGtdavi  120

         idrl++ymystap+p+++++ra+plaGfGyGlpisrlya+y+qGdlkl+sleG+Gtdavi

Q: 328   IDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVI  387

         ************************************************************

S: 121   ylkal  125

         y+kal

Q: 388   YIKAL  392

         ***85

Domain Sequence
(FASTA)

YVPSHLYHMV FELFKNAMRA TMEHHANRGV YPPIQVHVTL GNEDLTVKMS DRGGGVPLRK 60

IDRLFNYMYS TAPRPRVETS RAVPLAGFGY GLPISRLYAQ YFQGDLKLYS LEGYGTDAVI 120

YIKAL 125

Keyword

Complete proteome; Kinase; Pyruvate; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>