EKS-PAT-00062

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00062

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	350.4	6.6E-105	103	387	285

Status

Unreviewed

Ensembl Protein

ENSPTRP00000021901

UniProt Accession

H2QJ89;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000138395

Gene Synonyms/Alias

ENSG00000138395;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000012812	ENSPTRP00000021901	ENSPTRT00000023759

Organism

Pan troglodytes

Functional Description

Protein Length

435

Protein Sequence
(FASTA)

MGQELCAKTV QPGCSCYRCS EGGEAHSCRR SQPETTEAAF KLTDLKEASC SMTSFHPRGL 60

QAVRAQKFKS KRPRSNSDSF QEEDLRQGFQ WRKSLPFGAA SSYLNLEKLG EGSYATVYKG 120

ISRINGQLVA LKVISMNAEE GVPFTAIREA SLLKGLKHAN IVLLHDIIHT KETLTFVFEY 180

MHTDLAQYMS QHPGGLHPHN VRLFMFQLLR GLAYIHHQHV LHRDLKPQNL LISHLGELKL 240

ADFGLARAKS IPSQTYSSEV VTLWYRPPDA LLGATEYSSE LDIWGAGCIF IEMFQGQPLF 300

PGVSNILEQL EKIWEVLGVP TEDTWPGVSK LPNYNPEWFP LPTPRSLHVV WSRLGRVPEA 360

EDLASQMLKG FPRDRVSAQE ALVHDYFSAL PSQLYQLPDE ESLFTVSGVR LKPEMCDLLA 420

SYQKGHHPAQ FSKWW 435

Nucleotide Sequence
(FASTA)

ATGGGTCAAG AGCTGTGTGC AAAGACTGTA CAGCCTGGAT GCAGCTGCTA TCGTTGTTCA 60

GAGGGAGGCG AGGCACACAG CTGTCGGAGG AGTCAGCCTG AGACCACGGA GGCTGCGTTC 120

AAGCTAACAG ACCTAAAAGA AGCATCATGT TCCATGACTT CATTTCACCC CAGGGGACTT 180

CAAGCTGTCC GTGCCCAGAA GTTCAAGAGT AAAAGGCCAC GGAGTAACAG TGATTCTTTT 240

CAGGAAGAGG ATCTGAGGCA GGGTTTTCAG TGGAGGAAGA GCCTCCCTTT TGGGGCAGCC 300

TCATCTTACT TGAACTTGGA GAAGCTGGGT GAAGGCTCTT ATGCTACAGT TTACAAGGGG 360

ATTAGCAGAA TAAATGGACA ACTAGTGGCT TTAAAAGTCA TCAGCATGAA TGCAGAGGAA 420

GGAGTCCCAT TTACAGCTAT CCGAGAAGCT TCTCTCCTGA AGGGTTTGAA ACATGCCAAT 480

ATTGTGCTGC TGCATGACAT AATCCACACC AAAGAGACAC TGACATTCGT TTTTGAATAC 540

ATGCACACAG ACCTGGCCCA GTATATGTCT CAGCATCCAG GAGGGCTTCA TCCTCACAAT 600

GTCAGACTTT TCATGTTTCA ACTTTTGCGG GGCCTGGCGT ACATCCACCA CCAACACGTT 660

CTTCACAGGG ACCTGAAACC TCAGAACTTA CTCATCAGTC ACCTGGGAGA GCTCAAACTG 720

GCTGATTTTG GTCTTGCCCG GGCCAAGTCC ATTCCCAGCC AGACATACTC TTCAGAAGTC 780

GTGACCCTCT GGTACCGGCC CCCTGATGCT TTGCTGGGAG CCACTGAATA TTCCTCTGAG 840

CTGGACATAT GGGGTGCAGG CTGCATCTTT ATTGAAATGT TCCAGGGTCA ACCTTTGTTT 900

CCTGGGGTTT CCAACATCCT TGAACAGCTG GAGAAAATCT GGGAGGTGCT GGGAGTCCCT 960

ACAGAGGATA CTTGGCCGGG AGTCTCCAAG CTACCTAACT ACAATCCAGA ATGGTTCCCA 1020

CTGCCTACGC CTCGAAGCCT TCACGTTGTC TGGAGCAGGC TGGGCAGGGT TCCTGAAGCT 1080

GAAGACCTGG CCTCCCAGAT GCTAAAAGGC TTTCCCAGAG ACCGCGTCTC CGCCCAGGAA 1140

GCACTTGTTC ATGATTATTT CAGCGCCCTG CCATCTCAGC TGTACCAGCT TCCTGATGAG 1200

GAGTCTTTGT TTACAGTTTC AGGAGTGAGG CTAAAGCCAG AAATGTGTGA CCTTTTGGCC 1260

TCCTACCAGA AAGGCCACCA CCCAGCCCAG TTTAGCAAAT GGTGGTGA 1308

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ +g++vAlK i ++ e egvp+ta+rE sllk lkh+ni

Q: 103   YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI  161

         6789******************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 162   VLLHDIIH-TKETLTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHHQH  219

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLis+ g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+

Q: 220   VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS  279

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++DiW++gci+ e+++ +plf+g s+  +qle+i+++lg p+e++wp+vsklp+y+ + f

Q: 280   ELDIWGAGCIFIEMFQGQPLFPGVSNiLEQLEKIWEVLGVPTEDTWPGVSKLPNYNpEWF  339

         ***********************99967****************************8889

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         p  ++++l+ ++++l    +a dl +++l+  p++R+sa+eal h+yf

Q: 340   PLPTPRSLHVVWSRLGrvPEAEDLASQMLKGFPRDRVSAQEALVHDYF  387

         999999******999865679**************************9

Domain Sequence
(FASTA)

YLNLEKLGEG SYATVYKGIS RINGQLVALK VISMNAEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTFVFEYMH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHHQHVLH 120

RDLKPQNLLI SHLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSELD 180

IWGAGCIFIE MFQGQPLFPG VSNILEQLEK IWEVLGVPTE DTWPGVSKLP NYNPEWFPLP 240

TPRSLHVVWS RLGRVPEAED LASQMLKGFP RDRVSAQEAL VHDYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013