EPS-PAT-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PAT-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	238.3	1.1E-70	112	388	277

Status

Unreviewed

Ensembl Protein

ENSPTRP00000022396

UniProt Accession

H2QJQ0;

Protein Name

Protein Synonyms/Alias

Integrin-linked kinase-associated serine/threonine phosphatase;

Gene Name

ENSG00000132323

Gene Synonyms/Alias

ENSG00000132323; ILKAP;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000013088	ENSPTRP00000022396	ENSPTRT00000024275

Organism

Pan troglodytes

Functional Description

Protein Length

392

Protein Sequence
(FASTA)

MDLFGDLPEP ERSPRPAAGK EAQKGPLLFD DLPPASSTDS GSGGPLLFDD LPPASSGDSG 60

SLATSISQMV KTEGKGAKRK TSEEEKNGSE ELVEKKVCKA SSVIFGLKGY VAERKGEREE 120

MQDAHVILND ITEECRPPSS LITRVSYFAV FDGHGGIRAS KFAAQNLHQN LIRKFPKGDV 180

ISVEKTVKRC LLDTFKHTDE EFLKQASSQK PAWKDGSTAT CVLAVDNILY IANLGDSRAI 240

LCRYNEESQK HAALSLSKEH NPTQYEERMR IQKAGGNVRD GRVLGVLEVS RSIGDGQYKR 300

CGVTSVPDIR RCQLTPNDRF ILLACDGLFK VFTPEEAVNF ILSCLEDEKI QTREGKSAAD 360

ARYEAACNRL ANKAVQRGSA DNVTVMVVRI GH 392

Nucleotide Sequence
(FASTA)

ATGGACCTCT TCGGGGACCT GCCGGAGCCC GAGCGCTCGC CGCGCCCGGC TGCCGGGAAA 60

GAAGCTCAGA AAGGACCCCT GCTCTTTGAT GACCTCCCTC CGGCCAGCAG TACTGACTCA 120

GGATCAGGGG GACCTTTGCT TTTTGATGAT CTCCCACCCG CTAGCAGTGG CGATTCAGGT 180

TCTCTTGCCA CATCAATATC CCAGATGGTA AAGACTGAAG GGAAAGGAGC AAAGAGAAAA 240

ACCTCCGAGG AAGAGAAGAA TGGCAGTGAA GAGCTTGTGG AAAAGAAAGT TTGTAAAGCC 300

TCTTCGGTGA TCTTTGGTCT GAAGGGCTAT GTGGCTGAGC GGAAGGGTGA GAGGGAGGAG 360

ATGCAGGATG CCCACGTCAT TCTGAACGAC ATCACCGAGG AGTGTAGGCC CCCATCGTCC 420

CTCATTACTC GGGTTTCATA TTTTGCTGTT TTTGATGGAC ATGGAGGAAT TCGAGCCTCA 480

AAATTTGCTG CACAGAATTT GCATCAAAAC TTAATCAGAA AATTTCCTAA AGGAGATGTA 540

ATCAGTGTAG AGAAAACCGT GAAGAGATGC CTTTTGGACA CTTTCAAGCA TACTGATGAA 600

GAGTTCCTTA AACAAGCTTC CAGCCAGAAG CCTGCCTGGA AAGATGGGTC CACTGCCACG 660

TGTGTTCTGG CTGTAGACAA CATTCTTTAT ATTGCCAACC TCGGAGATAG TCGGGCAATC 720

TTGTGTCGTT ATAATGAGGA GAGTCAAAAA CATGCAGCCT TAAGCCTCAG CAAAGAGCAT 780

AATCCAACTC AGTATGAAGA GCGGATGAGG ATACAGAAGG CTGGAGGAAA CGTCAGGGAT 840

GGGCGTGTTT TGGGCGTGCT AGAGGTGTCA CGCTCCATTG GGGACGGGCA GTACAAGCGC 900

TGCGGTGTCA CCTCTGTGCC CGACATCAGA CGCTGCCAGC TGACCCCCAA TGACAGGTTC 960

ATTTTGTTGG CCTGTGATGG GCTCTTCAAG GTCTTTACCC CAGAAGAAGC CGTGAACTTC 1020

ATCTTGTCCT GTCTCGAGGA TGAAAAGATC CAGACCCGGG AAGGGAAGTC CGCAGCCGAC 1080

GCTCGCTACG AAGCAGCCTG CAACAGGCTG GCCAACAAGG CGGTGCAGCG GGGCTCAGCC 1140

GACAACGTCA CTGTGATGGT GGTGCGGATA GGGCACTGA 1179

Domain Profile

S: 6     vsvngrrnemedavtsspnflkspekkdr....laffgvyDGhggsevakfcseklheil  61

         ++ +g+r+em+da+ + +++ +++   +     +++f+v+DGhgg +++kf++++lh+ l

Q: 112   AERKGEREEMQDAHVILNDITEECRPPSSlitrVSYFAVFDGHGGIRASKFAAQNLHQNL  171

         567899**************9998887778899***************************

S: 62    aeele..sseseerkvkkalakaFlstdeelkvleeksldidk..sGstavvalikdskl  117

          +++   +  s e+ vk++l ++F++tdee+  l+++s+++ +   Gsta+++l  d+ l

Q: 172   IRKFPkgDVISVEKTVKRCLLDTFKHTDEEF--LKQASSQKPAwkDGSTATCVLAVDNIL  229

         ***9977788999******************..666666655577***************

S: 118   yvanvGdSravLcr.ngk.....avelssdHkpsredEleRieeaggsvilkdgaRvlGv  171

         y+an+GdSra+Lcr n++     a++ls++H+p++ +E+ Ri++agg+v +    RvlGv

Q: 230   YIANLGDSRAILCRyNEEsqkhaALSLSKEHNPTQYEERMRIQKAGGNVRDG---RVLGV  286

         **************7666799*****************************99...*****

S: 172   LavsRalGdlylk.pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle  230

         L+vsR++Gd+++k   vt+ P++  ++lt++d+f+ La+DGl++v+++eeav+++ ++le

Q: 287   LEVSRSIGDGQYKrCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLE  346

         *************555********************************************

S: 231   ............kkeaeqeaakkLvklalargskdnvsaivv  260

                      +++ ++a+++L++ a++rgs dnv+++vv

Q: 347   dekiqtregksaADARYEAACNRLANKAVQRGSADNVTVMVV  388

         ************9*************************9997

Domain Sequence
(FASTA)

AERKGEREEM QDAHVILNDI TEECRPPSSL ITRVSYFAVF DGHGGIRASK FAAQNLHQNL 60

IRKFPKGDVI SVEKTVKRCL LDTFKHTDEE FLKQASSQKP AWKDGSTATC VLAVDNILYI 120

ANLGDSRAIL CRYNEESQKH AALSLSKEHN PTQYEERMRI QKAGGNVRDG RVLGVLEVSR 180

SIGDGQYKRC GVTSVPDIRR CQLTPNDRFI LLACDGLFKV FTPEEAVNFI LSCLEDEKIQ 240

TREGKSAADA RYEAACNRLA NKAVQRGSAD NVTVMVV 277

Keyword

Complete proteome; Hydrolase; Integrin; Kinase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>