EPS-PAT-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PAT-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	197.4	3.3E-58	157	411	255

Status

Unreviewed

Ensembl Protein

ENSPTRP00000024314

UniProt Accession

H2QLB5;

Protein Name

Protein Synonyms/Alias

Protein phosphatase, Mg2+/Mn2+ dependent, 1F;

Gene Name

ENSG00000100034

Gene Synonyms/Alias

ENSG00000100034; PPM1F;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000014121	ENSPTRP00000024314	ENSPTRT00000026379

Organism

Pan troglodytes

Functional Description

Protein Length

454

Protein Sequence
(FASTA)

MSSGAPQKSS PMASGAEETP GFLDTLLQDF PALLNPEDPL PWKAPGTVLS QEEVEGELAE 60

LAMGFLGSRK APPPLAAALA HEAVSQLLQT DLSEFRKLPR EEEEEEEDDD EEEKAPVTLL 120

DAQSLARSFF NRLWEVAGQW QKQVPLAARA SQRQWLVSIH AIRNTRRKME DRHVSLPSFN 180

QLFGLFDPVN RAYFAVFDGH GGVDAARYAA VHVHTNAARQ PELPTDPAGA LREAFRRTDQ 240

MFLRKAKRER LQSGTTGVCA LIAGATLHVA WLGDSQVILV QQGQVVKLME PHRPERQDEK 300

ARIEALGGFV SHMDCWRVNG TLAVSRAIGD VFQKPYVSGE ADAASRALTG SEDYLLLACD 360

GFFDVIPHQE VVGLVQSHLT RQQGSGLRVA EELVAAARER GSHDNITVMV VFLRDPQELL 420

EGGNQGEGDP QAEGRRQDLP SSLPEPETQA PPRS 454

Nucleotide Sequence
(FASTA)

ATGTCCTCTG GAGCCCCACA GAAGAGCAGC CCAATGGCCA GTGGAGCTGA GGAGACCCCA 60

GGCTTCCTGG ACACGCTCCT GCAAGACTTC CCAGCCCTGC TGAACCCAGA GGACCCTCTG 120

CCATGGAAGG CCCCAGGGAC GGTGCTCAGC CAGGAGGAGG TGGAGGGCGA GCTGGCTGAG 180

CTGGCCATGG GCTTTCTGGG CAGCAGGAAG GCCCCGCCAC CACTTGCTGC TGCTCTGGCC 240

CACGAAGCAG TTTCACAGCT GCTACAGACA GACCTTTCCG AATTCAGGAA GTTGCCCAGG 300

GAGGAGGAAG AAGAGGAGGA GGACGATGAC GAGGAGGAAA AGGCCCCTGT GACCTTGCTG 360

GATGCCCAAA GCCTGGCACG GAGTTTCTTT AACCGCCTTT GGGAAGTCGC CGGCCAGTGG 420

CAGAAGCAGG TGCCATTGGC TGCCCGGGCC TCACAGCGGC AGTGGCTGGT CTCCATCCAC 480

GCCATCCGGA ACACTCGCCG CAAGATGGAG GACCGGCACG TGTCCCTCCC TTCCTTCAAC 540

CAGCTCTTCG GCTTGTTTGA CCCTGTGAAC CGCGCCTACT TTGCTGTGTT TGATGGTCAC 600

GGAGGCGTGG ATGCTGCGAG GTACGCCGCT GTCCACGTGC ACACCAACGC TGCGCGCCAG 660

CCAGAGCTGC CCACAGACCC TGCGGGAGCC CTCAGAGAAG CCTTCCGGCG CACCGACCAG 720

ATGTTTCTCA GGAAAGCCAA GCGAGAGCGG CTGCAGAGCG GCACCACAGG TGTGTGTGCG 780

CTCATTGCAG GAGCGACCCT GCACGTCGCC TGGCTCGGGG ACTCCCAGGT CATTTTGGTA 840

CAGCAGGGAC AGGTGGTGAA GCTGATGGAG CCACACAGAC CAGAACGGCA GGATGAGAAG 900

GCGCGCATTG AAGCATTGGG TGGCTTTGTG TCTCACATGG ACTGCTGGAG AGTCAACGGG 960

ACCCTGGCCG TCTCCAGAGC CATCGGGGAT GTCTTCCAGA AGCCCTACGT GTCTGGGGAG 1020

GCCGATGCAG CTTCCCGGGC GCTGACGGGC TCCGAGGACT ACCTGCTGCT TGCCTGTGAT 1080

GGCTTCTTTG ACGTCATACC CCACCAGGAA GTTGTTGGCC TGGTCCAGAG CCACTTGACC 1140

AGGCAGCAGG GCAGCGGGCT CCGTGTCGCC GAGGAGCTGG TGGCTGCGGC CCGGGAGCGG 1200

GGCTCCCACG ACAACATCAC GGTCATGGTG GTCTTCCTCA GGGACCCCCA AGAGCTGCTG 1260

GAGGGCGGGA ACCAGGGAGA AGGGGACCCC CAGGCAGAAG GGAGGAGGCA GGACTTGCCC 1320

TCCAGCCTTC CAGAACCTGA GACCCAGGCT CCACCAAGAA GCTAG 1365

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklhei  60

         v++ ++ + r++med++ s p+f +  +  d    a+f+v+DGhgg ++a++++ ++h+

Q: 157   VSIHAIRNTRRKMEDRHVSLPSFNQLFGLFDPvnRAYFAVFDGHGGVDAARYAAVHVHTN  216

         6678999******************99998887789************************

S: 61    laeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyva  120

          a++ e      ++   al++aF +td+ +  l +++ +  +sG+t v+ali + +l+va

Q: 217   AARQPE----LPTDPAGALREAFRRTDQMF--LRKAKRERLQSGTTGVCALIAGATLHVA  270

         ****77....7788889*************..8888889999******************

S: 121   nvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGd  180

          +GdS+++L ++g++v+l + H+p+r+dE++Rie+ gg v   d+ Rv+G LavsRa+Gd

Q: 271   WLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGD  330

         ********************************************99**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

         ++ kpyv+ e +  s  lt ++++l La+DG +dv++ +e+v lv+++l+ ++ +   +a

Q: 331   VFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVIPHQEVVGLVQSHLTrQQGSGLRVA  390

         ************************************************996777899***

S: 240   kkLvklalargskdnvsaivv  260

         ++Lv+ a++rgs+dn++++vv

Q: 391   EELVAAARERGSHDNITVMVV  411

         *****************9997

Domain Sequence
(FASTA)

VSIHAIRNTR RKMEDRHVSL PSFNQLFGLF DPVNRAYFAV FDGHGGVDAA RYAAVHVHTN 60

AARQPELPTD PAGALREAFR RTDQMFLRKA KRERLQSGTT GVCALIAGAT LHVAWLGDSQ 120

VILVQQGQVV KLMEPHRPER QDEKARIEAL GGFVSHMDCW RVNGTLAVSR AIGDVFQKPY 180

VSGEADAASR ALTGSEDYLL LACDGFFDVI PHQEVVGLVQ SHLTRQQGSG LRVAEELVAA 240

ARERGSHDNI TVMVV 255

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>