EKS-PAT-00307

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00307

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	329.2	1.7E-98	17	291	275

Status

Unreviewed

Ensembl Protein

ENSPTRP00000025450

UniProt Accession

H2QMA9;

Protein Name

Protein Synonyms/Alias

Oxidative-stress responsive 1;

Gene Name

ENSG00000172939

Gene Synonyms/Alias

ENSG00000172939; OXSR1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000014755	ENSPTRP00000025450	ENSPTRT00000027597

Organism

Pan troglodytes

Functional Description

Protein Length

527

Protein Sequence
(FASTA)

MSEDSSALPW SINRDDYELQ EVIGSGATAV VQAAYCAPKK EKVAIKRINL EKCQTSMDEL 60

LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDIIKHIVAK GEHKSGVLDE 120

STIATILREV LEGLEYLHKN GQIHRDVKAG NILLGEDGSV QIADFGVSAF LATGGDITRN 180

KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL 240

QNDPPSLETG VQDKEMLKKY GKSFRKMISL CLQKDPEKRP TAAELLRHKF FQKAKNKEFL 300

QEKILQRAPT ISERAKKVRR VPGSSGRLHK TEDGGWEWSD DEFDEESEEG KAAISQLRSP 360

RVKESISNSE LFPTTDPVGT LLQVPEQISA HLPQPAGQIP TQPTQVSLPP TAEPAKTAQA 420

LSSGSGSQET KIPISLVLRL RNSKKELNDI RFEFTPGRDT AEGVSQELIS AGLVDGRDLV 480

IVAANLQKIV EEPQSNRSVT FKLASGVEGS DIPDDGKLIG FAQLSIS 527

Nucleotide Sequence
(FASTA)

ATGTCCGAGG ACTCGAGCGC CCTGCCCTGG TCCATCAACA GGGACGATTA CGAGCTGCAG 60

GAGGTGATCG GGAGTGGAGC AACTGCTGTA GTCCAAGCAG CTTATTGTGC CCCTAAAAAG 120

GAGAAAGTGG CAATCAAACG GATAAACCTT GAGAAATGTC AAACTAGCAT GGATGAACTC 180

CTGAAAGAAA TTCAAGCCAT GAGTCAATGC CATCATCCTA ATATTGTATC TTACTACACA 240

TCTTTTGTGG TAAAAGATGA GCTGTGGCTT GTCATGAAGC TGCTAAGTGG AGGTTCTGTT 300

CTGGATATTA TTAAGCACAT TGTGGCAAAA GGGGAACACA AAAGTGGAGT CCTAGATGAA 360

TCTACCATTG CTACGATACT CCGAGAAGTA CTGGAAGGGC TGGAATATCT GCATAAAAAT 420

GGACAGATCC ACAGAGATGT GAAAGCTGGA AACATTCTTC TTGGAGAAGA TGGCTCAGTA 480

CAGATTGCAG ACTTTGGGGT TAGTGCTTTT TTAGCAACTG GTGGTGATAT TACCCGAAAT 540

AAAGTGAGAA AGACCTTTGT TGGCACCCCT TGTTGGATGG CACCTGAAGT TATGGAACAG 600

GTCCGTGGTT ATGATTTCAA AGCTGATATT TGGAGTTTTG GAATTACAGC AATTGAATTG 660

GCCACAGGGG CGGCTCCTTA TCATAAATAT CCACCAATGA AGGTTTTAAT GCTGACACTG 720

CAGAACGATC CTCCTTCTTT GGAAACTGGT GTTCAAGATA AAGAAATGCT GAAAAAATAT 780

GGAAAATCAT TTAGAAAAAT GATTTCATTG TGCCTTCAAA AAGATCCAGA AAAAAGACCA 840

ACAGCAGCAG AACTATTAAG GCACAAATTT TTCCAGAAAG CAAAGAATAA AGAATTTCTT 900

CAAGAAAAAA TATTGCAGAG AGCACCAACC ATTTCTGAAA GAGCAAAAAA GGTTCGGAGA 960

GTACCAGGTT CCAGTGGCCG TCTTCATAAG ACAGAGGATG GAGGCTGGGA GTGGAGTGAT 1020

GATGAATTTG ATGAAGAAAG TGAGGAAGGG AAAGCAGCAA TTTCACAACT CAGGTCTCCC 1080

CGAGTGAAAG AATCAATATC AAATTCTGAG CTCTTTCCAA CAACTGATCC TGTGGGTACT 1140

TTGCTCCAAG TTCCAGAACA GATCTCTGCT CATCTACCTC AGCCAGCTGG GCAGATTCCT 1200

ACACAGCCAA CTCAAGTCTC TCTCCCACCC ACCGCAGAGC CAGCAAAAAC AGCTCAGGCT 1260

TTGTCTTCAG GATCAGGTTC ACAAGAAACC AAGATCCCAA TCAGTCTAGT ACTAAGATTA 1320

AGGAATTCCA AAAAAGAACT AAATGATATT CGATTTGAAT TTACTCCTGG GAGAGATACA 1380

GCAGAGGGTG TCTCTCAGGA ACTCATTTCT GCTGGCCTGG TCGACGGAAG GGATTTAGTA 1440

ATAGTGGCAG CTAATTTGCA GAAAATTGTG GAAGAACCTC AGTCAAATCG ATCTGTCACT 1500

TTCAAACTGG CATCTGGTGT CGAAGGCTCA GATATTCCTG ATGATGGTAA ACTGATAGGA 1560

TTTGCCCAGC TCAGCATCAG CTAA 1584

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel+e+ig+Ga++ v++a++ +++e+vaik+inlek+ ++++el kei+++++++hpniv

Q: 17    YELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCqTSMDELLKEIQAMSQCHHPNIV  76

         99***********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E++ia+ilrevl++Ley

Q: 77    SYYTSFVVKDELWLVMKLLSGGSVLDIIKhivakgEHKSGVLDESTIATILREVLEGLEY  136

         *****************************9*99999999*********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 137   LHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATggdiTRNKvRKTFVGTPCWMAPE  196

         ***********************************99999988899**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaDiws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 197   VMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGvqdke  255

         ***5.9*********************************************976677778

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f+++++ clqk+pekRp+a+ell+hkF+

Q: 256   mlKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFF  291

         8899*******************************7

Domain Sequence
(FASTA)

YELQEVIGSG ATAVVQAAYC APKKEKVAIK RINLEKCQTS MDELLKEIQA MSQCHHPNIV 60

SYYTSFVVKD ELWLVMKLLS GGSVLDIIKH IVAKGEHKSG VLDESTIATI LREVLEGLEY 120

LHKNGQIHRD VKAGNILLGE DGSVQIADFG VSAFLATGGD ITRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADIWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPS LETGVQDKEM 240

LKKYGKSFRK MISLCLQKDP EKRPTAAELL RHKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

ptr:470791

;

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013