EKS-PAT-00302

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00302

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	344.4	4.1E-103	249	500	252

Status

Unreviewed

Ensembl Protein

ENSPTRP00000027164

UniProt Accession

H2QP14;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000180370

Gene Synonyms/Alias

ENSG00000180370;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000015787	ENSPTRP00000027164	ENSPTRT00000029436

Organism

Pan troglodytes

Functional Description

Protein Length

524

Protein Sequence
(FASTA)

MSDNGELEDK PPAPPVRMSS TIFSTGGKDP LSANHSLKPL PSVPEEKKPR HKIISIFSGT 60

EKGSKKKEKE RPEISPPSDF EHTIHVGFDA VTGEFTGMPE QWARLLQTSN ITKLEQKKNP 120

QAVLDVLKFY DSNTVKQKYL SFTPPEKDGF PSGTPALNAK GTEAPAVVTE EEDDDEETAP 180

PVIAPRPDHT KSIYTRSVID PVPAPVGDSH VDGAAKSLDK QKKKTKMTDE EIMEKLRTIV 240

SIGDPKKKYT RYEKIGQGAS GTVFTATDVA LGQEVAIKQI NLQKQPKKEL IINEILVMKE 300

LKNPNIVNCI FSYLVGDELF VVMEYLAGGS LTDVVTETCM DEAQIAAVCR ECLQALEFLH 360

ANQVIHRDIK SDNVLLGMEG SVKLTDFGFC AQITPEQSKR STMVGTPYWM APEVVTRKAY 420

GPKVDIWSLG IMAIEMVEGE PPYLNENPLR ALYLIATNGT PELQNPEKLS PIFRDFLNRC 480

LEMDVEKRGS AKELLQHPFL KLAKPLSSLT PLIMAAKEAM KSNR 524

Nucleotide Sequence
(FASTA)

ATGTCTGATA ACGGAGAACT GGAAGACAAG CCTCCAGCAC CTCCTGTGCG AATGAGCAGC 60

ACCATCTTTA GCACTGGAGG CAAAGACCCT TTGTCAGCCA ATCACAGTTT GAAACCTTTG 120

CCCTCTGTTC CAGAAGAGAA AAAGCCCAGG CATAAAATCA TCTCCATATT CTCAGGCACA 180

GAGAAAGGAA GTAAAAAGAA AGAAAAGGAA CGGCCAGAAA TTTCTCCTCC ATCTGATTTT 240

GAGCACACCA TCCATGTTGG CTTTGATGCT GTTACTGGAG AATTCACTGG CATGCCAGAA 300

CAGTGGGCTC GATTACTACA GACCTCCAAT ATCACCAAAC TAGAGCAAAA GAAGAATCCT 360

CAGGCTGTGC TGGATGTCCT AAAGTTCTAC GACTCCAACA CAGTGAAGCA GAAATATCTG 420

AGCTTTACTC CTCCTGAGAA AGATGGCTTT CCTTCTGGAA CACCAGCACT GAATGCCAAG 480

GGAACAGAAG CACCCGCAGT AGTGACAGAG GAGGAGGATG ATGATGAAGA GACTGCTCCT 540

CCCGTTATTG CCCCGCGACC GGATCATACG AAATCAATTT ACACACGGTC TGTAATTGAC 600

CCTGTTCCTG CACCAGTTGG TGATTCACAT GTTGATGGTG CTGCCAAGTC TTTAGACAAA 660

CAGAAAAAGA AGACTAAGAT GACAGATGAA GAGATTATGG AGAAATTAAG AACTATCGTG 720

AGCATAGGTG ACCCTAAGAA AAAATATACA AGATATGAAA AAATTGGACA AGGGGCTTCT 780

GGTACAGTTT TCACTGCTAC TGACGTTGCA TTGGGACAGG AGGTTGCTAT CAAACAAATT 840

AATTTACAGA AACAGCCAAA GAAGGAACTG ATCATTAACG AGATTCTGGT GATGAAAGAA 900

TTGAAAAATC CCAACATCGT TAATTGTATT TTTAGTTACC TGGTAGGAGA TGAATTGTTT 960

GTGGTCATGG AATACCTTGC TGGGGGGTCA CTCACTGATG TGGTAACAGA AACCTGCATG 1020

GATGAAGCAC AGATTGCTGC TGTATGCAGA GAGTGTTTAC AGGCATTGGA GTTTTTACAT 1080

GCTAATCAAG TGATCCACAG AGACATCAAA AGTGACAATG TACTTTTGGG AATGGAAGGA 1140

TCGGTTAAGC TCACTGACTT TGGTTTCTGT GCCCAGATCA CCCCTGAGCA GAGCAAACGC 1200

AGTACCATGG TCGGAACGCC ATACTGGATG GCACCAGAGG TGGTTACACG GAAAGCGTAT 1260

GGCCCTAAAG TCGACATATG GTCTCTGGGT ATCATGGCTA TTGAGATGGT AGAAGGAGAG 1320

CCTCCATACC TCAATGAAAA TCCCTTGAGG GCCTTGTACC TAATAGCAAC TAATGGAACC 1380

CCAGAACTTC AGAATCCAGA GAAACTTTCC CCAATATTTC GGGATTTCTT AAATCGATGT 1440

TTGGAAATGG ATGTGGAAAA AAGGGGTTCA GCCAAAGAAT TATTACAGCA TCCTTTCCTG 1500

AAACTGGCCA AACCGTTATC TAGCTTGACA CCACTGATCA TGGCAGCTAA AGAAGCAATG 1560

AAGAGTAACC GTTAA 1575

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         y+ +e+ig+Ga+g+v++a+++  g+ vaik+inl+kq+k+e++++ei v+k+lk+pniv+

Q: 249   YTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVN  308

         7889********************************************************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

          + s+l+ +el++vmeylagGsl+d+v+   ++ ++E qia+++re+l+aLe+lH+++vi

Q: 309   CIFSYLVGDELFVVMEYLAGGSLTDVVT---ETCMDEAQIAAVCRECLQALEFLHANQVI  365

         ****************************...9****************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrdik++n+Ll +eg+VkL+dfg++aq++ +++kr+t+vgtpywmAPEv++  +k Y  k

Q: 366   HRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--RKAYGPK  423

         ***************************************************..9******

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         +DiwslGI+aie++egepP+ +++pl+al++i++n +p+l++++k+s+ f++f+++cl+

Q: 424   VDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEM  483

         ************************************************************

S: 241   npekRpsasellkhkFl  257

         ++ekR sa+ell+h+Fl

Q: 484   DVEKRGSAKELLQHPFL  500

         ****************7

Domain Sequence
(FASTA)

YTRYEKIGQG ASGTVFTATD VALGQEVAIK QINLQKQPKK ELIINEILVM KELKNPNIVN 60

CIFSYLVGDE LFVVMEYLAG GSLTDVVTET CMDEAQIAAV CRECLQALEF LHANQVIHRD 120

IKSDNVLLGM EGSVKLTDFG FCAQITPEQS KRSTMVGTPY WMAPEVVTRK AYGPKVDIWS 180

LGIMAIEMVE GEPPYLNENP LRALYLIATN GTPELQNPEK LSPIFRDFLN RCLEMDVEKR 240

GSAKELLQHP FL 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:460965

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013