EPS-PAT-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PAT-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	237.9	1.5E-70	94	344	251

Status

Unreviewed

Ensembl Protein

ENSPTRP00000027948

UniProt Accession

H2QPV6;

Protein Name

Protein Synonyms/Alias

Protein phosphatase, Mg2+/Mn2+ dependent, 1K;

Gene Name

ENSG00000163644

Gene Synonyms/Alias

ENSG00000163644; PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000016271	ENSPTRP00000027948	ENSPTRT00000030277

Organism

Pan troglodytes

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSTAALITLV RSGGNQVRRR VLLSSRLLQD DRRVTPTCHS STSEPRCSRF DPDGSGSPAT 60

WDNFGIWDNR IDEPILLPPS IKYGKPIPKI SLENVGCASQ IGKRKENEDR FDFAQLTDEV 120

LYFAVYDGHG GPAAADFCHT HMEKCIMDLL PKEKNLETLL TLAFLEIDKA FSSHARLSAD 180

ATLLTSGTTA TVALLRDGIE LVVASVGDSR AILCRKGKPM KLTIDHTPER KDEKERIKKC 240

GGFVAWNSLG QPHVNGRLAM TRSIGDLDLK TSGVIAEPET KRIKLHHADD SFLVLTTDGI 300

NFMVNSQEIC DFVNQCHDPN EAAHAVTEQA IQYGTEDNST AVVVPFGAWG KYKNSEINFS 360

FSRSFASSGR WA 372

Nucleotide Sequence
(FASTA)

ATGTCAACAG CTGCCTTAAT TACTTTGGTC AGAAGTGGTG GGAACCAGGT GAGAAGGAGA 60

GTGCTGCTAA GCTCCCGCCT GCTGCAGGAC GACAGGCGGG TGACACCCAC GTGCCACAGC 120

TCCACTTCAG AGCCTAGGTG TTCTCGGTTT GACCCAGATG GTAGTGGGAG TCCAGCTACT 180

TGGGACAATT TTGGGATCTG GGATAACCGC ATTGATGAGC CAATTCTGCT GCCACCCAGC 240

ATTAAGTATG GCAAGCCAAT TCCCAAAATC AGCTTGGAAA ATGTGGGGTG CGCCTCACAG 300

ATTGGCAAAC GGAAAGAGAA TGAAGATCGG TTTGACTTCG CTCAGCTGAC AGATGAGGTC 360

CTGTACTTTG CAGTGTATGA TGGACACGGT GGACCTGCAG CAGCTGATTT CTGTCATACC 420

CACATGGAGA AATGTATTAT GGATTTGCTT CCTAAGGAGA AGAACTTGGA AACTCTGTTG 480

ACCTTGGCTT TTCTAGAAAT AGATAAAGCC TTTTCGAGTC ATGCCCGCCT GTCTGCTGAT 540

GCAACTCTTC TGACTTCTGG GACTACTGCA ACAGTAGCCC TATTGCGAGA TGGTATTGAA 600

CTGGTTGTAG CCAGTGTTGG GGACAGCCGG GCTATTTTGT GTAGAAAAGG AAAACCCATG 660

AAGCTGACCA TTGACCATAC TCCAGAAAGA AAAGATGAAA AAGAAAGGAT CAAGAAATGT 720

GGTGGTTTTG TAGCTTGGAA TAGTTTGGGG CAGCCTCACG TAAATGGCAG GCTTGCAATG 780

ACAAGAAGTA TTGGAGATTT GGACCTTAAG ACCAGTGGTG TCATAGCAGA ACCTGAAACT 840

AAGAGGATTA AGTTACATCA TGCTGATGAC AGCTTCCTGG TCCTCACCAC AGATGGAATT 900

AACTTCATGG TGAATAGTCA AGAGATTTGT GACTTTGTCA ATCAGTGCCA TGATCCCAAC 960

GAAGCAGCCC ATGCGGTGAC TGAACAGGCA ATACAGTACG GTACTGAGGA TAACAGTACT 1020

GCAGTAGTAG TGCCTTTTGG TGCCTGGGGA AAATATAAGA ACTCTGAAAT CAACTTCTCA 1080

TTCAGCAGAA GCTTTGCCTC CAGTGGACGA TGGGCCTGA 1119

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         +vg++s+ g+r+e ed++    +f++ +++   + +f+vyDGhgg  +a+fc++++++++

Q: 94    NVGCASQIGKRKENEDRF----DFAQLTDE---VLYFAVYDGHGGPAAADFCHTHMEKCI  146

         5899**************....57887666...78*************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.k  116

            l     +e+++++ l+ aFl++d+++   ++++l+ d+    sG+ta+val++d  +

Q: 147   MDLLP----KEKNLETLLTLAFLEIDKAF--SSHARLSADAtlltSGTTATVALLRDGiE  200

         ***87....********************..44444444445799*************9*

S: 117   lyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLav  174

         l+va vGdSra+Lcr+gk+++l+ dH+p+r+dE+eRi++ gg v+ ++ g+ +v+G La+

Q: 201   LVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSlGQpHVNGRLAM  260

         ********************************************98889999********

S: 175   sRalGdlylk.pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekk  232

         +R++Gdl+lk + v++ePe+  ++l++ d+ fl+L +DG+  +v+++e++++v+++++

Q: 261   TRSIGDLDLKtSGVIAEPETKRIKLHHADDsFLVLTTDGINFMVNSQEICDFVNQCHD--  318

         **********566************999999***************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           ++eaa+ ++++a+++g++dn +a+vv

Q: 319   --PNEAAHAVTEQAIQYGTEDNSTAVVV  344

         ..***********************997

Domain Sequence
(FASTA)

NVGCASQIGK RKENEDRFDF AQLTDEVLYF AVYDGHGGPA AADFCHTHME KCIMDLLPKE 60

KNLETLLTLA FLEIDKAFSS HARLSADATL LTSGTTATVA LLRDGIELVV ASVGDSRAIL 120

CRKGKPMKLT IDHTPERKDE KERIKKCGGF VAWNSLGQPH VNGRLAMTRS IGDLDLKTSG 180

VIAEPETKRI KLHHADDSFL VLTTDGINFM VNSQEICDFV NQCHDPNEAA HAVTEQAIQY 240

GTEDNSTAVV V 251

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>