EKS-PAT-00198

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00198

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	485.5	3.7E-146	4	286	283

Status

Unreviewed

Ensembl Protein

ENSPTRP00000029494

UniProt Accession

H2QRH8;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000006837

Gene Synonyms/Alias

ENSG00000006837;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000017239	ENSPTRP00000029494	ENSPTRT00000031919

Organism

Pan troglodytes

Functional Description

Protein Length

592

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKNTGQIV AIKIFYEKPE QSVNKIAMRE IKFLKQFHHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIDYLHSNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL SPHLQNIFSK SPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PADRISSSDL LHHEYFTRDG FIEKFMPELK 300

AKLLQEAKVN SLIKPKESSK ENELRKDERK TVYTNTLLSS SVLGKEIEKE KKPKEIKVRV 360

IKVKGRRGDI SEPKKKEYEG GLGQQDANEN VHPMSPDTKL VTIEPPNPIN PSTNCNGLKE 420

NPHCGGSVTM PPINLTNSNL MAANLSSNLF HPSVRLTERA KKRRTSSQSI GQVMPNSRQE 480

DPGPIQSQME KGIFNERTGH SDQMANENKR KLNFSRSDRK EFHFPELPVT IQSKDTKGME 540

VKQIKMLKRE SKKTESSKIP TLLNVDQNQE KQEGGDGHCE GKNLKRNRFF FW 592

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGAAAAGTG GGAGAGGGAA GTTACGGAAC AGTCATGAAA 60

TGTAAACATA AGAATACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA GAAACCAGAA 120

CAATCTGTCA ACAAAATTGC GATGAGAGAA ATAAAGTTTC TAAAGCAATT TCATCACGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTATTTGAA 240

TTTATTGACC ACACAGTATT AGATGAGTTA CAACATTATT GTCATGGACT AGAGAGTAAG 300

CGACTTAGAA AATACCTCTT CCAGATCCTT CGAGCAATTG ACTATCTTCA CAGTAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACTAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACACTA GCAGCTCCTG GGGACATTTA TACGGACTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCCGAA TTAGTATTAA AAGATACTTC TTATGGAAAA 540

CCTGTGGATA TCTGGGCTTT GGGCTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGTA GTTCTGATTT GGATTTACTC CATAAAATTG TTTTGAAAGT GGGCAATTTG 660

TCACCTCACT TGCAGAATAT CTTTTCCAAG AGCCCCATTT TTGCTGGGGT AGTTCTTCCT 720

CAAGTTCAAC ACCCCAAAAA TGCAAGAAAA AAATATCCAA AGCTTAATGG ATTGTTGGCA 780

GATATAGTTC ATGCTTGTTT ACAAATTGAT CCTGCTGACA GGATATCATC TAGTGATCTT 840

TTGCATCATG AGTATTTTAC TAGAGATGGA TTTATTGAAA AATTCATGCC AGAACTGAAA 900

GCTAAATTAC TGCAGGAAGC AAAAGTCAAT TCATTAATAA AGCCAAAAGA GAGTTCTAAA 960

GAAAATGAAC TCAGGAAAGA TGAAAGAAAA ACAGTTTATA CCAATACACT GCTAAGTAGT 1020

TCAGTTTTGG GAAAGGAAAT AGAAAAAGAG AAAAAGCCCA AGGAGATCAA AGTCAGAGTT 1080

ATTAAAGTCA AAGGAAGAAG AGGAGATATC TCAGAACCAA AAAAGAAAGA GTATGAAGGT 1140

GGACTTGGTC AACAGGATGC AAATGAAAAT GTTCATCCTA TGTCTCCAGA TACAAAACTT 1200

GTAACCATTG AACCACCAAA CCCTATCAAT CCCAGCACTA ACTGTAATGG CTTGAAAGAA 1260

AATCCACATT GCGGAGGTTC TGTGACAATG CCACCCATCA ATCTAACTAA CAGTAATTTG 1320

ATGGCTGCAA ATCTCAGTTC AAATCTCTTT CACCCCAGTG TGAGGTTAAC TGAAAGAGCA 1380

AAAAAGAGAC GCACTTCTTC ACAATCTATT GGACAAGTTA TGCCTAATAG CAGGCAAGAG 1440

GATCCAGGTC CTATTCAAAG CCAAATGGAG AAGGGTATAT TTAATGAGCG AACAGGTCAC 1500

AGTGACCAAA TGGCAAATGA GAACAAAAGG AAGCTGAATT TTTCCAGATC TGACAGGAAA 1560

GAATTCCATT TTCCAGAATT GCCTGTCACA ATACAGTCAA AAGATACAAA AGGAATGGAA 1620

GTTAAACAGA TAAAAATGCT GAAGAGGGAG TCAAAGAAAA CAGAGTCATC TAAGATACCA 1680

ACTTTACTTA ACGTGGATCA AAATCAAGAA AAACAAGAGG GTGGAGATGG CCATTGTGAG 1740

GGGAAGAATT TGAAGAGAAA CAGGTTTTTT TTCTGGTAG 1779

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ ++v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYEKPE-QSVNKIAMREIKFLKQFHHENL  62

         9***********************************9.99********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+ai+++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifsk+++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpa+r+s+++ll+heyf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KNTGQIVAIK IFYEKPEQSV NKIAMREIKF LKQFHHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI DYLHSNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLSPH LQNIFSKSPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAD RISSSDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:462064

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013