EKS-PAT-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/YANK	504.0	9.0E-152	23	281	259

Status

Unreviewed

Ensembl Protein

ENSPTRP00000059021

UniProt Accession

H2RDK3;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000169302

Gene Synonyms/Alias

ENSG00000169302;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000017379	ENSPTRP00000059021	ENSPTRT00000067433

Organism

Pan troglodytes

Functional Description

Protein Length

407

Protein Sequence
(FASTA)

MGANTSRKPP VFDENEDVNF DHFEILRAIG KGSFGKVCIV QKNDTKKMYA MKYMNKQKCV 60

ERNEVRNVFK ELQIMQGLEH PFLVNLWYSF QDEEDMFMVV DLLLGGDLRY HLQQNVHFKE 120

ETVKLFICEL AMALDYLQNQ RIIHRDMKPD NILLDEHGHV HITDFNIAAM LPRETQITTM 180

AGTKPYMAPE MFSSRKGAGY SFAVDWWSLG VTAYELLRGR RPYHIRSSTS SKEIVHTFET 240

TVVTYPSAWS QEMVSLLKKL LEPNPDQRFS QLSDVQNFPY MNDINWDAVF QKRLIPGFIP 300

NKGRLNCDPT FELEEMILES KPLHKKKKRL AKKEKDMRKC DSSQTCLLQE HLDSVQKEFI 360

IFNREKVNRD FNKRQPNLAL EQTKDPQVTN GQMDTGLSET FQTSKVS 407

Nucleotide Sequence
(FASTA)

ATGGGAGCCA ACACTTCAAG AAAACCACCA GTGTTTGATG AAAATGAAGA TGTCAACTTT 60

GACCACTTTG AAATTTTGCG AGCCATTGGG AAAGGCAGTT TTGGGAAGGT CTGCATTGTA 120

CAGAAGAATG ATACCAAGAA GATGTACGCA ATGAAGTACA TGAATAAACA AAAGTGCGTG 180

GAGCGCAATG AAGTGAGAAA TGTCTTCAAG GAACTCCAGA TCATGCAGGG TCTGGAGCAC 240

CCTTTCCTGG TTAATTTGTG GTATTCCTTC CAAGATGAGG AAGACATGTT CATGGTGGTG 300

GACCTCCTGC TGGGTGGAGA CCTGCGTTAT CACCTGCAAC AGAACGTCCA CTTCAAGGAA 360

GAAACAGTGA AGCTCTTCAT ATGTGAGCTG GCCATGGCCC TGGACTACCT GCAGAACCAG 420

CGCATCATTC ACAGGGATAT GAAGCCTGAC AATATTTTAC TTGATGAACA TGGGCACGTG 480

CACATCACAG ATTTCAACAT TGCTGCGATG CTGCCCAGGG AGACACAGAT TACCACCATG 540

GCTGGCACCA AGCCTTACAT GGCACCTGAG ATGTTCAGCT CCAGAAAAGG AGCAGGCTAT 600

TCCTTTGCTG TTGACTGGTG GTCCCTGGGA GTGACGGCAT ATGAACTGCT GAGAGGCCGG 660

AGACCATATC ATATTCGCTC CAGTACTTCC AGCAAGGAAA TTGTACACAC GTTTGAGACG 720

ACTGTTGTAA CTTACCCTTC TGCCTGGTCA CAGGAAATGG TGTCACTTCT TAAAAAGCTA 780

CTCGAACCTA ATCCAGACCA ACGATTTTCT CAGTTATCTG ATGTCCAGAA CTTCCCGTAT 840

ATGAATGATA TAAACTGGGA TGCAGTTTTT CAGAAGAGGC TCATTCCAGG TTTCATTCCT 900

AATAAAGGCA GGCTGAATTG TGATCCTACC TTTGAACTTG AGGAAATGAT TTTGGAGTCC 960

AAACCTCTAC ACAAGAAAAA AAAGCGTCTG GCAAAAAAGG AGAAGGATAT GAGGAAATGC 1020

GATTCTTCTC AGACATGTCT TCTTCAAGAG CACCTTGACT CTGTCCAGAA GGAGTTCATA 1080

ATTTTCAACA GAGAAAAAGT AAACAGGGAC TTTAACAAAA GACAACCAAA TCTAGCCTTG 1140

GAACAAACCA AAGACCCACA AGTGACAAAT GGACAAATGG ACACAGGACT CAGTGAGACT 1200

TTTCAGACCT CGAAAGTTTC ATAA 1224

Domain Profile

S: 1     fqilraiGkGsfGkvcivqkrdtkklyalkymnkqkcierdevrnvlrelellqelehpf  60

         f+ilraiGkGsfGkvcivqk+dtkk+ya+kymnkqkc+er+evrnv++el+++q+lehpf

Q: 23    FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPF  82

         89**********************************************************

S: 61    lvnlwysfqdeedlfmvvdlllGGdlryhlqqnvkfsedtvklyicelalaleylqeqki  120

         lvnlwysfqdeed+fmvvdlllGGdlryhlqqnv+f+e+tvkl+icela+al+ylq+q+i

Q: 83    LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELAMALDYLQNQRI  142

         ************************************************************

S: 121   ihrdikpdnilldekGhahltdfniatvlkdeeratslaGtkpymapevfasylekeaGy  180

         ihrd+kpdnillde+Gh+h+tdfnia++l +e+++t++aGtkpymape+f+s  +k+aGy

Q: 143   IHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSS--RKGAGY  200

         ****************************************************..9*****

S: 181   sfevdwwslGvvayellrgrrpyeiksstaveeivnlfktesvkypstwskelvallkkl  240

         sf+vdwwslGv+ayellrgrrpy+i+sst+++eiv++f+t++v+yps+ws+e+v+llkkl

Q: 201   SFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKL  260

         ************************************************************

S: 241   levdpekrlssledikkapyl  261

         le +p++r+s+l+d++++py+

Q: 261   LEPNPDQRFSQLSDVQNFPYM  281

         *******************97

Domain Sequence
(FASTA)

FEILRAIGKG SFGKVCIVQK NDTKKMYAMK YMNKQKCVER NEVRNVFKEL QIMQGLEHPF 60

LVNLWYSFQD EEDMFMVVDL LLGGDLRYHL QQNVHFKEET VKLFICELAM ALDYLQNQRI 120

IHRDMKPDNI LLDEHGHVHI TDFNIAAMLP RETQITTMAG TKPYMAPEMF SSRKGAGYSF 180

AVDWWSLGVT AYELLRGRRP YHIRSSTSSK EIVHTFETTV VTYPSAWSQE MVSLLKKLLE 240

PNPDQRFSQL SDVQNFPYM 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013