EKS-PAT-00448

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00448

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	525.6	2.0E-158	13	270	258

Status

Unreviewed

Ensembl Protein

ENSPTRP00000029757

UniProt Accession

H2QRT0;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000070808

Gene Synonyms/Alias

ENSG00000070808;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000017414	ENSPTRP00000029757	ENSPTRT00000032212

Organism

Pan troglodytes

Functional Description

Protein Length

487

Protein Sequence
(FASTA)

MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS ARGRCLISVC 60

PTVTNCLAPP TVRLHDSISE EGHHYLIFDL VTGGELFEDI VAREYYSEAD ASHCIQQILE 120

AVLHCHQMGV VHRDLKPENL LLASKLKGAA VKLADFGLAI EVEGEQQAWF GFAGTPGYLS 180

PEVLRKDPYG KPVDLWACGV ILYILLVGYP PFWDEDQHRL YQQIKAGAYD FPSPEWDTVT 240

PEAKDLINKM LTINPSKRIT AAEALKHPWI SHRSTVASCM HRQETVDCLK KFNARRKLKG 300

AILTTMLATR NFSGRWQDSH LFSLFFQKRK SSSSVQLMES SESTNTTIED EDTKVRKQEI 360

IKVTEQLIEA ISNGDFESYT KMCDPGMTAF EPEALGNLVE GLDFHRFYFE NLWSRNSKPV 420

HTTILNPHIH LMGDESACIA YIRITQYLDA GGIPRTAQSE ETRVWHRRDG KWQIVHFHRS 480

GAPSVLP 487

Nucleotide Sequence
(FASTA)

ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 60

AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCCGGCCA GGAGTATGCT 120

GCCAAGATCA TCAACACAAA GAAGCTGTCA GCCAGAGGTA GGTGCCTGAT CTCAGTGTGT 180

CCCACTGTAA CCAACTGCCT TGCCCCGCCC ACAGTCCGAC TACATGACAG CATCTCAGAG 240

GAGGGACACC ACTACCTGAT CTTCGACCTG GTCACTGGTG GGGAACTGTT TGAAGATATC 300

GTGGCCCGGG AGTATTACAG TGAGGCGGAT GCCAGTCACT GTATCCAGCA GATCCTGGAG 360

GCTGTGCTGC ACTGCCACCA GATGGGGGTG GTGCACCGGG ACCTGAAGCC TGAGAATCTG 420

TTGCTGGCCT CCAAGCTCAA GGGTGCCGCA GTGAAGCTGG CAGACTTTGG CCTGGCCATA 480

GAGGTGGAGG GGGAGCAGCA GGCATGGTTT GGGTTTGCAG GGACTCCTGG ATACCTCTCC 540

CCAGAAGTGC TGCGGAAGGA CCCGTACGGG AAGCCTGTGG ACCTGTGGGC TTGTGGGGTC 600

ATCCTGTACA TCCTGCTGGT TGGGTACCCC CCGTTCTGGG ATGAGGACCA GCACCGCCTG 660

TACCAGCAGA TCAAAGCCGG CGCCTATGAT TTCCCATCGC CGGAATGGGA CACTGTCACC 720

CCGGAAGCCA AGGATCTGAT CAATAAGATG CTGACCATTA ACCCATCCAA ACGCATCACA 780

GCTGCCGAAG CCCTTAAGCA CCCCTGGATC TCGCACCGCT CCACCGTGGC ATCCTGCATG 840

CACAGACAGG AGACCGTGGA CTGCCTGAAG AAGTTCAATG CCAGGAGGAA ACTGAAGGGA 900

GCCATTCTCA CCACGATGCT GGCCACCAGG AACTTCTCCG GTAGGTGGCA GGACTCCCAT 960

CTCTTCTCCT TGTTTTTCCA GAAAAGAAAG TCCAGTTCCA GCGTTCAGTT AATGGAATCC 1020

TCAGAGAGCA CCAACACCAC CATCGAGGAT GAAGACACCA AAGTGCGGAA ACAGGAAATT 1080

ATAAAAGTGA CAGAGCAGCT GATTGAAGCC ATAAGCAATG GAGATTTTGA GTCCTACACG 1140

AAGATGTGCG ACCCTGGCAT GACAGCCTTC GAACCTGAGG CCCTGGGGAA CCTGGTTGAG 1200

GGCCTGGACT TCCATCGATT CTATTTTGAA AACCTGTGGT CCCGGAACAG CAAGCCCGTG 1260

CACACCACCA TCCTGAATCC CCACATCCAC CTGATGGGCG ACGAGTCAGC CTGCATCGCC 1320

TACATCCGCA TCACGCAGTA CCTGGACGCT GGCGGCATCC CACGCACCGC CCAGTCGGAG 1380

GAGACCCGCG TCTGGCACCG CCGGGACGGC AAATGGCAGA TCGTCCACTT CCACAGATCT 1440

GGGGCGCCCT CCGTCCTGCC C 1461

Domain Profile

S: 1     yqlfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpni  60

         yqlfeelgkgafsvvrrcvkv +gqeyaakiintkklsar    +     +   l  p

Q: 13    YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARGRCLISVCPTVTNCLA-PPT  71

         9****************************************999998888888886.567

S: 61    vrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvv  120

         vrlhdsiseeg+hyl+fdlvtggelfedivareyyseadashciqqile+vlh+hq+gvv

Q: 72    VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV  131

         9***********************************************************

S: 121   hrdlkpenlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygk  180

         hrdlkpenlllask+kgaavkladfglaiev+g+qqawfgfagtpgylspevlrkdpygk

Q: 132   HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK  191

         ************************************************************

S: 181   pvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkml  240

         pvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkml

Q: 192   PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML  251

         ************************************************************

S: 241   tinpakritadealkhpwi  259

         tinp+krita+ealkhpwi

Q: 252   TINPSKRITAAEALKHPWI  270

         ******************8

Domain Sequence
(FASTA)

YQLFEELGKG AFSVVRRCVK VLAGQEYAAK IINTKKLSAR GRCLISVCPT VTNCLAPPTV 60

RLHDSISEEG HHYLIFDLVT GGELFEDIVA REYYSEADAS HCIQQILEAV LHCHQMGVVH 120

RDLKPENLLL ASKLKGAAVK LADFGLAIEV EGEQQAWFGF AGTPGYLSPE VLRKDPYGKP 180

VDLWACGVIL YILLVGYPPF WDEDQHRLYQ QIKAGAYDFP SPEWDTVTPE AKDLINKMLT 240

INPSKRITAA EALKHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013