EKS-PAT-00258

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00258

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	400.9	4.1E-120	687	1003	317

Status

Unreviewed

Ensembl Protein

ENSPTRP00000050634

UniProt Accession

H2R7N8;

Protein Name

Protein Synonyms/Alias

PRP4 pre-mRNA processing factor 4 homolog B;

Gene Name

ENSG00000112739

Gene Synonyms/Alias

ENSG00000112739; PRPF4B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000017683	ENSPTRP00000050634	ENSPTRT00000050921

Organism

Pan troglodytes

Functional Description

Protein Length

1007

Protein Sequence
(FASTA)

MAAAETQSLR EQPEMEDANS EKSINEENGE VSEDQSQNKH SRHKKKKHKH RSKHKKHKHS 60

SEEDKDKKHK HKHKHKKHKR KEVIDASDKE GMSPAKRTKL DDLALLEDLE KQRALIKAEL 120

DNELMEGKVQ SGMGLILQGY ESGSEEEGEI HEKARNGNRS STRSSSTKGK LELVDNKITT 180

KKRSKSRSKE RTRHRSDKKK SKGGIEIVKE KTTRSKSKER KKSKSPSKRS KSQDQARKSK 240

SPTLRRRSQE KIGKARSPTD DKVKIEDKSK SKDRKKSPII NESRSRDRGK KSRSPVDLRG 300

KSKDRRSRSK ERKSKRSETD KEKKPIKSPS KDASSGKENR SPSRRPGRSP KRRSLSPKPR 360

DKSRRSRSPL LNDRRSKQSK SPSRTLSPGR RAKSRSLERK RREPERRRLS SPRTRPRDDI 420

LSRRERSKDA SPINRWSPTR RRSRSPIRRR SRSPLRRSRS PRRRSRSPRR RDRGRRSRSR 480

LRRRSRSRGG RRRRSRSKVK EDKFKGSLSE GMKVEQESSS DDNLEDFDVE EEDEEALIEQ 540

RRIQRQAIVQ KYKYLAEDSN MSVPSEPSSP QSSTRTRSPS PDDILERVAA DVKEYERENV 600

DTFEASVKAK HNLMTVEQNN GSSQKKLLAP DMFTESDDMF AAYFDSARLR AAGIGKDFKE 660

NPNLRDNWTD AEGYYRVNIG EVLDKRYNVY GYTGQGVFSN VVRARDNARA NQEVAVKIIR 720

NNELMQKTGL KELEFLKKLN DADPDDKFHC LRLFRHFYHK QHLCLVFEPL SMNLREVLKK 780

YGKDVGLHIK AVRSYSQQLF LALKLLKRCN ILHADIKPDN ILVNESKTIL KLCDFGSASH 840

VADNDITPYL VSRFYRAPEI IIGKSYDYGI DMWSVGCTLY ELYTGKILFP GKTNNHMLKL 900

AMDLKGKMPN KMIRKGVFKD QHFDQNLNFM YIEVDKVTER EKVTVMSTIN PTKDLLADLI 960

GCQRLPEDQR KKVHQLKDLL DQILMLDPAK RISINQALQH AFIQEKI 1007

Nucleotide Sequence
(FASTA)

ATGGCCGCCG CGGAGACCCA GTCGCTACGG GAGCAGCCAG AGATGGAAGA TGCTAATTCT 60

GAAAAGAGTA TAAATGAAGA AAATGGAGAA GTATCAGAAG ACCAGTCTCA AAATAAGCAC 120

AGTCGTCACA AAAAAAAGAA GCATAAACAC AGAAGTAAAC ATAAGAAACA TAAACATTCC 180

TCAGAAGAAG ACAAGGATAA AAAACATAAA CATAAGCATA AACATAAGAA ACACAAAAGA 240

AAAGAGGTTA TTGATGCTTC TGATAAAGAG GGTATGTCTC CAGCAAAAAG AACTAAACTT 300

GATGATTTAG CTTTGCTAGA AGACTTGGAA AAACAGAGAG CCTTGATTAA GGCCGAACTT 360

GATAATGAGT TAATGGAAGG AAAGGTCCAG TCTGGTATGG GGCTCATTTT GCAAGGTTAT 420

GAGTCTGGCT CTGAAGAAGA GGGGGAGATT CATGAAAAGG CAAGAAATGG AAATAGGTCT 480

AGTACTAGAT CTTCAAGTAC AAAGGGGAAA CTTGAACTTG TGGACAATAA AATTACTACA 540

AAAAAACGAA GTAAAAGCAG ATCCAAAGAA CGGACTAGAC ATAGGTCTGA TAAAAAGAAA 600

AGTAAGGGGG GTATTGAAAT CGTTAAAGAG AAAACAACTA GGAGCAAGTC AAAGGAGAGG 660

AAAAAATCTA AAAGCCCATC CAAAAGAAGT AAGTCTCAAG ATCAAGCAAG GAAATCAAAA 720

TCCCCTACCC TTAGAAGGCG ATCTCAAGAG AAAATTGGTA AGGCCAGATC TCCTACTGAT 780

GATAAGGTTA AAATTGAAGA TAAAAGTAAA TCAAAAGATA GGAAAAAATC CCCAATTATA 840

AATGAAAGTA GAAGTCGCGA TCGAGGTAAA AAATCCAGAT CCCCAGTTGA TTTAAGAGGT 900

AAATCCAAAG ACAGAAGGTC ACGGTCCAAA GAGAGAAAAT CAAAACGGTC TGAAACTGAT 960

AAAGAAAAGA AGCCAATTAA ATCTCCCTCT AAAGATGCTT CATCTGGGAA AGAAAATAGG 1020

TCACCCAGCA GAAGACCTGG TCGTAGTCCT AAAAGAAGAA GTTTGTCTCC AAAACCACGT 1080

GATAAATCAA GAAGAAGCAG GTCTCCACTT TTGAATGATA GAAGATCTAA GCAGAGCAAA 1140

TCCCCCTCGC GGACACTGTC ACCTGGGAGA AGAGCCAAGA GCCGATCCTT AGAAAGAAAA 1200

CGACGAGAAC CAGAGAGGAG ACGACTTTCT TCTCCAAGAA CACGACCTCG AGATGATATC 1260

CTCAGTAGAC GTGAAAGATC AAAAGATGCC AGCCCCATCA ATAGATGGTC TCCAACCCGA 1320

AGAAGAAGTA GATCTCCCAT TAGAAGGAGG TCTCGTTCCC CACTCAGACG TAGCAGGTCT 1380

CCAAGAAGAA GAAGCAGATC TCCTCGGAGA AGGGACAGAG GTCGGAGGAG CAGATCACGC 1440

TTGCGAAGGC GGTCTCGATC ACGCGGTGGT CGTAGACGAA GGAGCAGAAG CAAAGTAAAG 1500

GAAGATAAAT TTAAAGGAAG TCTTTCTGAA GGAATGAAAG TTGAGCAGGA ATCTTCGTCT 1560

GATGATAACC TTGAAGACTT TGATGTAGAG GAAGAAGATG AAGAAGCCCT AATAGAACAG 1620

AGAAGAATCC AAAGGCAGGC AATTGTTCAG AAATATAAAT ACCTTGCTGA AGATAGCAAC 1680

ATGTCTGTGC CATCTGAACC AAGCAGCCCC CAGAGCAGTA CGAGAACACG ATCACCATCT 1740

CCAGATGACA TTCTGGAGCG AGTAGCTGCT GATGTTAAAG AGTATGAACG GGAAAATGTT 1800

GATACATTTG AGGCCTCAGT GAAAGCCAAG CATAATCTAA TGACAGTTGA ACAGAATAAT 1860

GGTTCATCTC AGAAGAAGTT GTTGGCACCT GATATGTTTA CAGAATCTGA TGATATGTTT 1920

GCTGCGTATT TTGATAGTGC TCGTCTTCGG GCCGCTGGCA TTGGAAAAGA TTTCAAAGAG 1980

AATCCCAACC TCAGAGATAA CTGGACCGAT GCAGAAGGCT ATTATCGTGT GAACATAGGT 2040

GAAGTCCTAG ATAAACGTTA CAATGTGTAT GGCTACACTG GGCAAGGTGT ATTCAGTAAT 2100

GTTGTACGAG CCAGAGATAA TGCAAGAGCC AACCAAGAAG TGGCTGTAAA GATCATCAGA 2160

AACAATGAGC TCATGCAAAA GACTGGTTTA AAAGAATTAG AGTTCTTGAA AAAACTTAAT 2220

GATGCTGATC CTGATGACAA ATTTCATTGT CTGAGACTCT TCAGGCACTT CTATCACAAG 2280

CAGCATCTTT GTCTCGTATT CGAGCCTCTC AGCATGAACT TACGAGAGGT GTTAAAAAAA 2340

TATGGTAAAG ATGTTGGTCT TCATATTAAA GCTGTAAGAT CCTATAGTCA GCAGTTGTTC 2400

CTGGCATTGA AACTCCTTAA AAGATGCAAT ATCCTACATG CAGATATCAA GCCAGACAAT 2460

ATCCTGGTTA ATGAATCCAA AACTATTTTA AAGCTTTGCG ATTTTGGGTC GGCTTCACAT 2520

GTTGCGGATA ATGACATAAC ACCTTATCTT GTCAGTAGAT TTTATCGTGC TCCTGAAATC 2580

ATTATAGGTA AAAGCTATGA CTATGGTATA GATATGTGGT CTGTAGGTTG CACCTTATAC 2640

GAACTCTATA CTGGAAAAAT TTTATTCCCT GGCAAAACCA ATAACCATAT GCTGAAGCTT 2700

GCAATGGATC TCAAAGGAAA GATGCCAAAT AAGATGATTC GAAAAGGTGT GTTCAAAGAT 2760

CAGCATTTTG ATCAAAATCT CAACTTCATG TACATAGAAG TTGATAAAGT AACAGAGAGG 2820

GAGAAAGTTA CTGTTATGAG CACCATTAAT CCAACTAAGG ACCTGTTGGC TGACTTGATT 2880

GGGTGCCAGA GACTTCCTGA AGACCAACGT AAGAAAGTAC ACCAGCTAAA GGACTTGTTG 2940

GACCAGATTC TGATGTTGGA CCCAGCTAAA CGAATTAGCA TCAACCAGGC CCTACAGCAT 3000

GCCTTCATCC AGGAAAAAAT TTAA 3024

Domain Profile

S: 1     yevlevigkGsfgqVvkaldk.ktkeivaikiiknkkrfarqaqeEveiLeklnkkdkee  59

         y+v+ ++g+G+f++Vv+a+d+ +++++va+kii+n++ +++++ +E+e+L+kln++d+++

Q: 687   YNVYGYTGQGVFSNVVRARDNaRANQEVAVKIIRNNELMQKTGLKELEFLKKLNDADPDD  746

         99******************9889************************************

S: 60    kynvvrllelfvfrnhlclvfellsqnLyellkknkfs.glslklvrklaqqilkaLklL  118

         k++++rl+++f++++hlclvfe ls+nL+e+lkk++++ gl++k+vr+++qq++ aLklL

Q: 747   KFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDvGLHIKAVRSYSQQLFLALKLL  806

         ************************************999*********************

S: 119   kelkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglk  178

         k+++i+HaD+KP+Nil++e+k+  +k++DFGs+s+v++++i++y++srfYraPEii+g++

Q: 807   KRCNILHADIKPDNILVNESKTI-LKLCDFGSASHVADNDITPYLVSRFYRAPEIIIGKS  865

         *********************99.************************************

S: 179   ydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftk  238

         yd+ iDmWS+Gc+l+El+tGk+LfpG++++++l+l ++++g++p+k+++k+  ++++f++

Q: 866   YDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMIRKGVFKDQHFDQ  925

         ************************************************************

S: 239   keapkyilktkksdrkkklvlnvkkaakkrkaplskelgealkekedkl.fkdllkrmle  297

         + +++yi ++k+++r+k++v+++++ +k+  a+l  +++ +++++++ + +kdll+++l+

Q: 926   NLNFMYIEVDKVTEREKVTVMSTINPTKDLLADLIGCQRLPEDQRKKVHqLKDLLDQILM  985

         ***********************************************999**********

S: 298   ldpakRitpkealkhpfv  315

         ldpakRi++++al+h f+

Q: 986   LDPAKRISINQALQHAFI  1003

         *****************7

Domain Sequence
(FASTA)

YNVYGYTGQG VFSNVVRARD NARANQEVAV KIIRNNELMQ KTGLKELEFL KKLNDADPDD 60

KFHCLRLFRH FYHKQHLCLV FEPLSMNLRE VLKKYGKDVG LHIKAVRSYS QQLFLALKLL 120

KRCNILHADI KPDNILVNES KTILKLCDFG SASHVADNDI TPYLVSRFYR APEIIIGKSY 180

DYGIDMWSVG CTLYELYTGK ILFPGKTNNH MLKLAMDLKG KMPNKMIRKG VFKDQHFDQN 240

LNFMYIEVDK VTEREKVTVM STINPTKDLL ADLIGCQRLP EDQRKKVHQL KDLLDQILML 300

DPAKRISINQ ALQHAFI 317

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>