EKS-PAT-00190

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00190

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	509.8	1.8E-153	4	284	281

Status

Unreviewed

Ensembl Protein

ENSPTRP00000042420

UniProt Accession

H2R1I5;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000111837

Gene Synonyms/Alias

ENSG00000111837;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000017722	ENSPTRP00000042420	ENSPTRT00000043180

Organism

Pan troglodytes

Functional Description

Protein Length

623

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYMLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASNEAIQL MTEMLNWDPK KRPTASQALK HSYFQVGQVL GPSSNHLESK 300

QSLNKQLQPL ESKPSLVEVE PKPLPDIIDQ AVGQPQPKTS QQPLQPIQPP QNLSVQQPPK 360

QQSQEKPPQT LFPSIVKNMP TKPNGTLSHK SGRRRWGQTI FKSGDSWEEL EDYDFGASHS 420

KKPSMGVFKE KRKKDSPFRL PEPVPSGSNH STGENKSLPA VTSLKSDSEL STAPTSKQYY 480

LKQSRYLPGV NPKKVSLIAS GKEINPHTWS NQLFPKSLGP IGAELAFKRR NAGNLGSYAT 540

YDQSGYIPSF LKKEVQSAGQ RIHLAPLNAT ASEYTWNTKT GRGQFSGRTY NPTAKNLNIV 600

NRAQPIPSVH GRTDWVAKYG GHR 623

Nucleotide Sequence
(FASTA)

ATGAACCGAT ACACAACCAT GAGACAGTTG GGGGACGGCA CGTATGGGAG TGTGCTTATG 60

GGCAAGAGTA ATGAATCCGG GGAGCTGGTG GCCATCAAAA GGATGAAGAG AAAGTTCTAT 120

TCTTGGGATG AATGCATGAA CTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTTATTA AATTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTCTA TCAATTAATG AAAGACAGAA ACAAGTTGTT CCCTGAATCA 300

GTCATCAGAA ATATTATGTA TCAAATATTG CAAGGGCTGG CTTTTATCCA TAAACACGGC 360

TTTTTTCATA GGGACATGAA ACCAGAAAAC TTGCTTTGTA TGGGCCCAGA GCTTGTGAAA 420

ATTGCTGATT TTGGACTTGC AAGAGAATTA AGGTCACAGC CACCATACAC TGATTATGTC 480

TCTACCAGAT GGTATCGTGC CCCTGAAGTT TTACTGAGAT CTTCAGTTTA TAGTTCTCCC 540

ATTGATGTGT GGGCTGTTGG AAGTATCATG GCTGAACTCT ATATGTTAAG GCCACTTTTC 600

CCAGGGACAA GTGAGGTCGA TGAAATCTTT AAAATTTGCC AAGTTTTAGG GACTCCCAAA 660

AAAAGTGACT GGCCAGAAGG ATACCAGCTG GCATCCTCTA TGAACTTCCG TTTTCCCCAG 720

TGTGTTCCTA TAAACTTAAA AACTCTTATT CCCAATGCCA GTAATGAAGC TATTCAGCTC 780

ATGACCGAAA TGTTGAATTG GGATCCAAAG AAACGACCAA CAGCAAGCCA GGCATTGAAA 840

CACTCATATT TTCAAGTTGG TCAGGTATTA GGCCCTTCGT CAAATCATCT GGAATCAAAA 900

CAGTCTTTAA ATAAGCAGCT GCAACCATTA GAATCAAAGC CATCTTTAGT TGAGGTAGAG 960

CCTAAGCCTC TGCCGGATAT AATTGATCAG GCTGTTGGAC AACCCCAGCC AAAAACTAGC 1020

CAGCAGCCAC TGCAGCCCAT TCAGCCGCCA CAGAACCTGA GCGTCCAGCA ACCTCCAAAG 1080

CAACAGAGTC AGGAGAAACC GCCACAAACG CTATTCCCGA GCATCGTCAA AAACATGCCA 1140

ACTAAGCCAA ATGGCACACT GAGTCATAAA AGTGGTAGGA GGCGTTGGGG TCAGACTATC 1200

TTCAAGTCTG GAGATAGCTG GGAAGAGTTG GAGGACTATG ATTTCGGAGC CTCCCATTCC 1260

AAGAAGCCAA GCATGGGTGT TTTTAAAGAA AAAAGGAAAA AAGATTCTCC ATTTCGGCTT 1320

CCAGAGCCAG TACCCTCAGG CTCCAACCAC TCGACAGGGG AAAACAAGAG CTTACCTGCT 1380

GTTACTTCCC TAAAATCTGA TTCTGAATTG TCAACTGCTC CAACCTCTAA ACAGTACTAC 1440

TTGAAACAAT CAAGATATCT TCCAGGTGTG AATCCCAAGA AGGTGTCCTT GATAGCCAGT 1500

GGAAAGGAAA TAAACCCCCA CACTTGGAGC AACCAGTTAT TCCCCAAGTC ACTGGGACCC 1560

ATCGGGGCAG AACTTGCTTT CAAAAGGAGA AATGCAGGAA ATCTTGGAAG TTATGCTACT 1620

TACGATCAGT CGGGATATAT TCCTTCCTTT CTCAAAAAAG AAGTGCAGTC AGCTGGCCAG 1680

AGGATCCACT TAGCACCTCT CAATGCAACG GCTTCAGAAT ATACCTGGAA CACAAAAACT 1740

GGTCGGGGGC AGTTTTCAGG ACGTACTTAT AATCCTACAG CAAAAAACCT AAATATTGTG 1800

AACCGTGCAC AGCCCATTCC CTCAGTGCAC GGGAGGACAG ACTGGGTGGC CAAGTATGGA 1860

GGCCACCGGT AG 1872

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l++++l++dP++r+ta+qalk+ yf

Q: 241   CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHSYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YMLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SNEAIQLMTE MLNWDPKKRP TASQALKHSY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:746604

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013