EKS-PAT-00189

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00189

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	514.9	5.3E-155	4	284	281

Status

Unreviewed

Ensembl Protein

ENSPTRP00000031242

UniProt Accession

H2QT73;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000112144

Gene Synonyms/Alias

ENSG00000112144;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000018286	ENSPTRP00000031242	ENSPTRT00000033803

Organism

Pan troglodytes

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

MNRYTTIRQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 120

FFHRDLKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSTNYSSP 180

IEVWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK KTDWPEGYQL SSAMNFRWPQ 240

CVPNNLKTLI PNASSEAVQL LRDMLQWDPK KRPTASQALR YPYFQVGHPL GSTTQNLQDS 300

EKPQKGILEK AGPPPHIKPV PPAQPPTKPQ TRISSRQHQA SQPPLHLTYP YKAEISRTDH 360

PSHLQEDKPS PLLFPSLHNK HPQSKITAGL EHKNGEIKPK SRRRWGLISR STKDSDDWAD 420

LDDLDFSPSL SRIDLKNKKR QSDDTLCRFE SVLDLKPSEP VGTGNSAPTQ TSYQRRDTPT 480

LRSAAKQHYL KHSRYLPGIS IRNGILSNPG KEFIPPNPWS SSGLSGKSSG TMSVISKVNS 540

VGSSSTSSSG LTGNYVPSFL KKEIGSAMQR VHLAPIPDPS PGYSSLKAMR PHPGRPFFHT 600

QPRSTPGLIP RPPAAQPVHG RTDWASKYAS RR 632

Nucleotide Sequence
(FASTA)

ATGAATAGAT ACACAACAAT CAGGCAGCTC GGGGATGGAA CCTACGGTTC CGTCCTGCTG 60

GGAAGAAGCA TTGAGTCTGG GGAGCTGATT GCTATTAAAA AAATGAAAAG AAAATTTTAT 120

TCCTGGGAGG AATGCATGAA CCTTCGGGAG GTTAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTCA AATTAAAAGA AGTTATCAGG GAAAATGATC ATCTTTATTT TATCTTCGAG 240

TACATGAAGG AAAATCTTTA CCAGCTCATT AAAGAGAGAA ATAAGTTGTT TCCTGAGTCT 300

GCTATAAGGA ATATCATGTA TCAGATATTA CAAGGACTCG CATTTATTCA CAAACACGGC 360

TTCTTTCATC GAGACTTAAA GCCTGAGAAC CTCCTCTGCA TGGGACCAGA ACTTGTGAAA 420

ATTGCAGACT TTGGTTTGGC CCGAGAAATA CGATCAAAAC CTCCATATAC AGATTATGTA 480

TCTACCAGAT GGTACAGGGC TCCAGAAGTA CTCCTGAGGT CTACCAACTA CAGCTCCCCC 540

ATTGAAGTCT GGGCGGTGGG CTGCATCATG GCAGAAGTTT ACACCCTCAG GCCACTCTTC 600

CCTGGAGCCA GTGAAATTGA CACAATATTT AAAATTTGCC AAGTGCTGGG GACACCAAAA 660

AAGACTGACT GGCCTGAAGG CTATCAACTT TCAAGTGCAA TGAACTTCCG TTGGCCACAG 720

TGTGTACCCA ATAACTTAAA GACCTTGATT CCCAATGCTA GCAGTGAAGC AGTCCAGCTC 780

CTGAGAGACA TGCTTCAGTG GGATCCCAAG AAACGACCAA CAGCTAGTCA GGCACTTCGA 840

TATCCTTACT TCCAAGTTGG ACACCCACTA GGCAGCACCA CACAAAACCT TCAGGATTCA 900

GAAAAACCAC AGAAAGGCAT CCTGGAAAAG GCAGGCCCAC CTCCTCATAT TAAGCCAGTC 960

CCACCTGCCC AGCCGCCAAC CAAGCCACAG ACACGAATTT CTTCACGACA GCATCAAGCC 1020

AGCCAGCCCC CTCTGCATCT CACGTACCCC TACAAAGCAG AGATCTCCAG GACAGATCAC 1080

CCAAGCCATC TCCAGGAGGA CAAGCCAAGC CCGTTGCTTT TCCCATCCCT CCACAACAAG 1140

CATCCACAGT CGAAAATCAC AGCTGGCCTG GAGCACAAAA ATGGTGAGAT AAAGCCAAAG 1200

AGTAGGAGAA GGTGGGGTCT TATTTCCAGG TCAACAAAGG ATTCAGATGA TTGGGCTGAC 1260

TTGGATGACT TGGATTTCAG TCCATCCCTC AGCAGGATTG ACCTGAAAAA CAAGAAAAGA 1320

CAGAGTGATG ACACTCTCTG CAGGTTTGAG AGTGTTTTGG ACCTGAAGCC CTCTGAGCCT 1380

GTGGGCACAG GAAACAGTGC CCCCACCCAG ACGTCATATC AGCGGCGAGA CACGCCCACC 1440

CTGAGATCTG CAGCCAAGCA GCACTATTTG AAGCACTCTC GATACTTGCC TGGGATCAGT 1500

ATAAGAAATG GCATACTCTC GAATCCAGGC AAGGAATTTA TTCCACCTAA TCCATGGTCT 1560

AGTTCTGGCT TGTCTGGAAA ATCTTCAGGG ACAATGTCAG TAATCAGCAA AGTAAATTCA 1620

GTTGGTTCCA GCTCTACAAG TTCTAGTGGA CTGACTGGAA ACTATGTCCC TTCCTTTCTG 1680

AAAAAAGAAA TCGGTTCTGC TATGCAGAGG GTACACCTAG CACCTATTCC AGACCCTTCC 1740

CCTGGTTATT CCTCCCTGAA GGCCATGAGA CCTCATCCTG GGCGACCATT CTTCCACACC 1800

CAGCCTAGAA GCACTCCTGG GTTGATACCA CGGCCTCCAG CCGCCCAGCC AGTGCATGGC 1860

CGGACAGACT GGGCTTCCAA GTACGCATCT CGGCGATGA 1899

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++i++lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+++e+m+enlyqlik+r+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare+rsk+PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +++wavGc++aev++lrplfPGaseid+ifki++vlGtPkk++w+e+y+l+sa+n+++pq

Q: 181   IEVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++ll+d+l++dP++r+ta+qal+ypyf

Q: 241   CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTIRQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFIFEYMK ENLYQLIKER NKLFPESAIR NIMYQILQGL AFIHKHGFFH 120

RDLKPENLLC MGPELVKIAD FGLAREIRSK PPYTDYVSTR WYRAPEVLLR STNYSSPIEV 180

WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC QVLGTPKKTD WPEGYQLSSA MNFRWPQCVP 240

NNLKTLIPNA SSEAVQLLRD MLQWDPKKRP TASQALRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

ptr:462772

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013