EKS-PAT-00065

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00065

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	336.6	1.1E-100	21	330	310

Status

Unreviewed

Ensembl Protein

ENSPTRP00000031594

UniProt Accession

H2QTK0;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000155111

Gene Synonyms/Alias

ENSG00000155111;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000018500	ENSPTRP00000031594	ENSPTRT00000034183

Organism

Pan troglodytes

Functional Description

Protein Length

497

Protein Sequence
(FASTA)

RIKLAAERER VEDLFEYEGC KVGRGTYGHV YKARRKNGKD EKEYALKQIE GTGISMSACR 60

EIALLRELKH PNVIALQKVF LSHSDRKVWL LFDYAEHDLW HIIKFHRASK ANKKPMQLPR 120

SMVKSLLYQI LDGIHYLHAN WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK 180

PLADLDPVVV TFWYRAPELL LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN 240

PFHHDQLDRI FSVMGFPADK DWEDIRKMPE YPTLQKDFRR TTYANSSLIK YMEKHKVKPD 300

SKVFLLLQKL LTMDPTKRIT SEQALQDPYF QEDPLPTLDV FAGCQIPYPK REFLNEDDPE 360

EKGDKNQQQQ QNQHQQPTAP PQQAAAPPQA PPPQQNSTQT NGTAGGAGAG VGGTGAGLQH 420

SQDSSLNQVP PNKKPRLGPS GANSGGPVMP SDYQHSSSRL NYQSSVQGSS QSQSTLGYSS 480

SSQQSSQYHP SHQAHRY 497

Nucleotide Sequence
(FASTA)

AGAATCAAGC TGGCGGCGGA GCGGGAGCGG GTGGAGGATT TGTTTGAGTA CGAAGGGTGC 60

AAAGTGGGAC GCGGCACCTA CGGTCACGTC TACAAGGCGA GGCGGAAAAA TGGAAAAGAT 120

GAAAAGGAAT ATGCATTGAA GCAAATTGAA GGCACAGGAA TATCCATGTC GGCTTGTAGA 180

GAGATTGCAC TTTTGCGAGA ATTGAAGCAC CCTAATGTGA TTGCATTGCA GAAGGTGTTC 240

CTTTCTCACA GTGACAGGAA GGTATGGCTG CTGTTTGATT ATGCAGAGCA TGACTTGTGG 300

CATATTATTA AGTTTCACCG TGCATCAAAA GCAAATAAAA AGCCCATGCA GTTGCCAAGA 360

TCTATGGTTA AATCCTTACT TTACCAGATT CTTGATGGTA TCCATTACCT CCATGCAAAT 420

TGGGTGCTTC ACAGAGACTT GAAACCAGCA AATATCCTAG TAATGGGAGA AGGTCCTGAG 480

AGGGGGAGAG TCAAAATAGC TGACATGGGT TTTGCCAGAT TATTCAATTC TCCTCTAAAG 540

CCACTAGCAG ATTTGGATCC AGTAGTTGTG ACATTTTGGT ATCGGGCTCC AGAACTTTTG 600

CTTGGTGCAA GGCATTATAC AAAGGCCATT GATATATGGG CAATAGGTTG TATATTTGCT 660

GAATTGTTGA CTTCGGAACC TATTTTTCAC TGTCGTCAGG AAGATATAAA AACAAGCAAT 720

CCCTTTCATC ATGATCAACT GGATCGGATA TTTAGTGTCA TGGGGTTTCC TGCAGATAAA 780

GACTGGGAAG ATATTAGAAA GATGCCAGAA TATCCCACAC TTCAAAAAGA CTTTAGAAGA 840

ACAACGTATG CCAACAGTAG CCTCATAAAG TACATGGAGA AACACAAGGT CAAGCCTGAC 900

AGCAAAGTGT TCCTCTTGCT TCAGAAACTC CTGACCATGG ATCCAACCAA GAGAATTACC 960

TCGGAGCAAG CTCTGCAGGA TCCCTATTTT CAGGAGGACC CTTTGCCAAC ATTAGATGTA 1020

TTTGCCGGCT GCCAGATTCC ATACCCCAAA CGAGAATTCC TTAATGAAGA TGATCCTGAA 1080

GAAAAAGGTG ACAAGAATCA GCAACAGCAG CAGAACCAGC ATCAGCAGCC CACAGCCCCT 1140

CCACAGCAGG CAGCAGCCCC TCCACAGGCA CCCCCACCGC AGCAGAACAG CACCCAGACC 1200

AACGGGACCG CAGGTGGGGC TGGGGCCGGG GTCGGGGGCA CCGGAGCAGG GTTGCAGCAC 1260

AGCCAGGACT CCAGCCTGAA CCAGGTGCCT CCAAACAAGA AGCCACGGCT AGGGCCTTCA 1320

GGCGCAAACT CAGGTGGACC TGTGATGCCC TCGGATTATC AGCACTCCAG TTCTCGCCTG 1380

AATTACCAAA GCAGCGTTCA GGGATCCTCT CAGTCCCAGA GCACACTTGG CTACTCTTCC 1440

TCGTCTCAGC AGAGCTCACA GTACCACCCA TCTCACCAGG CCCACCGGTA CTGA 1494

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vyka++k+  +++ +AlK+i    e +g++++a+rEi+ll+elkh+n++ L

Q: 21    KVGRGTYGHVYKARRKNgkDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL  76

         79************987446668******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k ++++       +l++++vksll+q+l+g++y

Q: 77    QKVFLsHSDRKVWLLFDYAEHDLWHIIKFHRASkankkpmQLPRSMVKSLLYQILDGIHY  136

         ****94555*********************9999999999********************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 137   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  196

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 197   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpfhHDQLDRIFSVMGF  256

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pey    k+f+++++   +l ++++k k    +k + ll+kll++dp+

Q: 257   PADKDWEDIRKMPEYPtlqKDFRRTTYAnsSLIKYMEKHKvkpdSKVFLLLQKLLTMDPT  316

         ***************965457777666544666666443333545689************

S: 271   kRisakealqhkyf  284

         kRi++++alq++yf

Q: 317   KRITSEQALQDPYF  330

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKARRKNGKD EKEYALKQIE GTGISMSACR EIALLRELKH PNVIALQKVF 60

LSHSDRKVWL LFDYAEHDLW HIIKFHRASK ANKKPMQLPR SMVKSLLYQI LDGIHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PFHHDQLDRI FSVMGFPADK 240

DWEDIRKMPE YPTLQKDFRR TTYANSSLIK YMEKHKVKPD SKVFLLLQKL LTMDPTKRIT 300

SEQALQDPYF 310

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013