EKS-PAT-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PAT-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	387.9	2.4E-116	167	448	282

Status

Unreviewed

Ensembl Protein

ENSPTRP00000037496

UniProt Accession

H2QYI7;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000102225

Gene Synonyms/Alias

ENSG00000102225;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPTRG00000021840	ENSPTRP00000037496	ENSPTRT00000040578

Organism

Pan troglodytes

Functional Description

Protein Length

498

Protein Sequence
(FASTA)

IAMDRMKKIK RQLSMTLRGG RGIDKTNGAP EQIGLDESGG GGGSDPGEAP TRAAPGELRS 60

ARGPLSSAPE IVHEDLKMGS DGESDQASAT SSDEVQSPVR VRMRNHPPRK ISTEDINKRL 120

SLPADIRLPE GYLEKLTLNS PIFDKPLSRR LRRVSLSEIG FGKLETYIKL DKLGEGTYAT 180

VYKGKSKLTD NLVALKEIRL EHEEGAPCTA IREVSLLKDL KHANIVTLHD IIHTEKSLTL 240

VFEYLDKDLK QYLDDCGNII NMHNVKLFLF QLLRGLAYCH RQKVLHRDLK PQNLLINERG 300

ELKLADFGLA RAKSIPTKTY SNEVVTLWYR PPDILLGSTD YSTQIDMWGV GCIFYEMATG 360

RPLFPGSTVE EQLHFIFRIL GTPTEETWPG ILSNEEFKTY NYPKYRAEAL LSHAPRLDSD 420

GADLLTKLLQ FEGRNRISAE DAMKHPFFLS LGERIHKLPD TTSIFALKEI QLQKEASLRS 480

SSMPDSGRPA FRVVDTEF 498

Nucleotide Sequence
(FASTA)

ATCGCCATGG ATCGGATGAA GAAGATCAAA CGGCAGCTGT CAATGACACT CCGAGGTGGC 60

CGAGGCATAG ACAAGACCAA TGGTGCCCCT GAGCAGATAG GCCTGGATGA GAGTGGTGGT 120

GGTGGCGGCA GTGACCCTGG AGAGGCCCCC ACACGTGCTG CTCCTGGGGA ACTTCGTTCT 180

GCACGGGGCC CACTCAGCTC TGCACCAGAG ATTGTGCACG AGGACTTGAA GATGGGGTCT 240

GATGGGGAGA GTGACCAGGC TTCAGCCACG TCCTCGGATG AGGTGCAGTC TCCAGTGAGA 300

GTGCGTATGC GCAACCATCC CCCACGCAAG ATCTCCACTG AGGACATCAA CAAGCGCCTA 360

TCGCTACCAG CTGATATCCG GCTGCCTGAG GGCTACCTGG AGAAGCTGAC CCTCAATAGC 420

CCCATCTTTG ACAAGCCCCT CAGCCGCCGC CTCCGTCGTG TCAGCCTATC TGAGATTGGC 480

TTTGGGAAAC TGGAGACCTA CATTAAGCTG GACAAGCTGG GCGAGGGTAC CTATGCCACC 540

GTCTACAAAG GCAAAAGCAA GCTCACAGAC AACCTTGTGG CACTCAAGGA GATCAGACTG 600

GAACATGAAG AGGGGGCACC CTGCACCGCC ATCCGGGAAG TGTCCCTGCT CAAGGACCTC 660

AAACACGCCA ACATCGTTAC GCTACATGAC ATTATCCACA CGGAGAAGTC CCTCACCCTT 720

GTCTTTGAGT ACCTGGACAA GGACCTGAAG CAGTACCTGG ATGACTGTGG GAACATCATC 780

AACATGCACA ACGTGAAACT GTTCCTGTTC CAGCTGCTCC GTGGCCTGGC CTACTGCCAC 840

CGGCAGAAGG TGCTACACCG AGACCTCAAG CCCCAGAACC TGCTCATCAA CGAGAGGGGA 900

GAGCTCAAGC TGGCTGACTT TGGCCTGGCC CGAGCCAAGT CAATCCCAAC AAAGACATAC 960

TCCAATGAGG TGGTGACACT GTGGTACCGG CCCCCTGACA TCCTGCTTGG GTCCACGGAC 1020

TACTCCACTC AGATTGACAT GTGGGGTGTG GGCTGCATCT TCTATGAGAT GGCCACAGGC 1080

CGTCCCCTCT TTCCGGGCTC CACGGTGGAG GAACAGCTAC ACTTCATCTT CCGTATCTTA 1140

GGAACCCCAA CTGAGGAGAC GTGGCCAGGC ATCCTGTCCA ACGAGGAGTT CAAGACATAC 1200

AACTACCCCA AGTACCGAGC CGAGGCCCTT TTGAGCCACG CACCCCGACT TGATAGCGAC 1260

GGGGCCGACC TCCTCACCAA GCTGTTGCAG TTTGAGGGTC GAAATCGGAT CTCCGCAGAG 1320

GATGCCATGA AACATCCATT CTTCCTCAGT CTGGGGGAGC GGATCCACAA ACTTCCTGAC 1380

ACTACTTCCA TATTTGCACT AAAGGAGATT CAGCTACAAA AGGAGGCCAG CCTTCGGTCT 1440

TCGTCGATGC CTGACTCAGG CAGGCCAGCT TTCCGTGTGG TGGACACCGA GTTCTAA 1497

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 167   YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  225

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ +  +++++vk +l+qll+glay+H++k

Q: 226   VTLHDIIH-TEKSLTLVFEYLDKDLKQYLDDCGN-IINMHNVKLFLFQLLRGLAYCHRQK  283

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 284   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  343

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 344   QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKtYNYP  403

         *******************************************************88***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l++++ dll+kll+++ ++Risa++a++h++f

Q: 404   KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF  448

         *******************************************98

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNIINMHNVK LFLFQLLRGL AYCHRQKVLH 120

RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR 240

AEALLSHAPR LDSDGADLLT KLLQFEGRNR ISAEDAMKHP FF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013