EKS-PTV-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PTV-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Jak	330.6	6.4E-99	821	1088	268

Status

Unreviewed

Ensembl Protein

ENSPVAP00000016395

Gene Name

JAK3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPVAG00000017376	ENSPVAP00000016395	ENSPVAT00000017376

Organism

Pteropus vampyrus

Protein Length

1089

Protein Sequence
(FASTA)

MVPPSEETPL ISQRSCSLSS SEASVLHVLL PPRAPGPLQR LSSFGDHSAE ELCVRAAKAS 60

GILPVYHSLF ALATEDLSCW FPPSHIFSVE DTGTQVLVYR LRFYFPNWFG LEKCHRFGLR 120

KDLASAILDL PVLEHLFAQH RNDLVSGRFH VGLGLKEQGE CLSLAVLDLA RMAREQAQRP 180

EELLKTVSYK ACLPPGLRNL IQGLSFVTRR RIRRTVRQAL CRVAACQADR HSLMAKYIMD 240

LERLDPARAA ETFLVGLPGV AGGQDAPGLL HVAGDSGIAW SSGEQEVFQP FCDFPEIVDI 300

SIKQALRVGT AGEHRLVTVT RTDNQILEAE FPGLPAALSF VALVDGYFRL TVDSRHYFCK 360

EVAPPRLLEE VAQQCHGPIT LDFAINKLKM GGSLPGSYVL RRSPQDFDSF LLTVCVQTPL 420

GPDYKGCLIR CDPTGAYSLA GLGRPHSSLR ELLAACWDGG LHVDGVALNL TFCCTPRPKE 480

KSNLIVVRRG CSPPTSSPVQ PHSGCQLSQM TFHKIPADSL EWHENLGHGS FTKIYRGCRH 540

EAMDGEPRKT EVLLKVLDAK HKNCMESFLE AASLMSQVSY QHLVLLHGVC MAGDSIMVQE 600

FVHLGALDTY LRKCGQLVPA SWKLQVIKQL AYALNYLEDK GLPHGNVSAR KVLLAREGAE 660

GSPPFIKLSD PGVSPTVLSL EMLTDRIPWV APECLQEART LGLEADKWGF GATVWEVFSG 720

VTMPISTLDP AKKLQFYEER QQLPAPKWME LALLIQQCMA YEPGHRPSFR AVIRDLNNLI 780

TSDYELLSDP TPGALAPRDG LWNGAQLYAC QDPTIFEERH LKYISQLGKG NFGSVELCRY 840

DPLGDNTGAL VAVKQLQHSG PDQQRDFQRE IQILKALHSD FIVKYRGVSY GPGRQSLRLV 900

MEYLPSGCLR DFLQRHRARL GAGRLLLYAS QICKGMEYLG SCRCVHRDLA ARNILVESET 960

HVKIADFGLA KLLPLDKDYY VVREPGQSPI FWYAPESLSD NIFSRQSDVW SFGVVLYELF 1020

TYSDKSCSPS AEFLRMMGCE RDIPALCRLL DLLAEGQRLP APPACPGEVH ELMKLCWAPS 1080

PQDRPTFSA 1089

Nucleotide Sequence
(FASTA)

ATGGTGCCTC CGAGTGAGGA GACACCCCTG ATCTCTCAGC GCTCTTGCAG CCTCTCGTCT 60

TCAGAGGCTA GTGTGCTGCA TGTGCTGCTG CCACCTCGGG CCCCTGGACC CCTGCAGCGT 120

CTATCTTCCT TTGGGGACCA CTCGGCTGAA GAGCTGTGTG TTCGGGCTGC TAAGGCCAGT 180

GGCATCCTGC CTGTGTATCA CTCCCTCTTT GCTCTGGCCA CGGAGGACCT GTCCTGCTGG 240

TTCCCCCCGA GCCACATCTT CTCCGTGGAG GACACAGGCA CCCAAGTCCT TGTCTACAGG 300

CTCCGCTTTT ACTTCCCCAA CTGGTTTGGG CTAGAGAAGT GTCACCGCTT CGGGCTTCGA 360

AAGGACTTGG CTAGTGCCAT CCTTGACCTG CCAGTTCTGG AGCACCTCTT CGCCCAGCAC 420

CGCAATGACC TGGTGAGCGG CCGCTTCCAC GTGGGCCTTG GCCTCAAGGA GCAGGGCGAA 480

TGTCTCAGCT TGGCAGTGCT GGACCTGGCC AGGATGGCCC GCGAGCAGGC CCAGCGGCCA 540

GAGGAGCTGC TAAAGACCGT CAGCTACAAG GCCTGCTTGC CCCCTGGCCT GCGCAACCTG 600

ATCCAGGGCC TGAGCTTCGT GACTCGGAGG CGCATTCGGA GGACTGTACG CCAGGCCCTG 660

TGCCGCGTGG CCGCCTGCCA GGCTGACAGG CACTCGCTCA TGGCCAAGTA CATCATGGAC 720

TTGGAGCGAC TGGACCCGGC CAGGGCCGCT GAGACCTTCC TCGTGGGCCT CCCCGGGGTT 780

GCTGGTGGTC AGGATGCACC GGGGCTGCTC CACGTGGCTG GTGACAGCGG CATCGCCTGG 840

AGTTCAGGAG AACAGGAGGT CTTCCAGCCC TTTTGCGACT TTCCAGAAAT CGTGGACATC 900

AGCATCAAGC AGGCTCTACG CGTTGGCACG GCCGGGGAGC ACCGCCTGGT CACTGTCACC 960

AGGACAGACA ACCAGATCCT GGAGGCCGAG TTCCCTGGGC TGCCCGCCGC GTTGTCCTTT 1020

GTGGCACTCG TGGATGGCTA CTTCCGGCTG ACTGTTGACT CTCGGCACTA CTTCTGCAAG 1080

GAGGTAGCAC CGCCGCGGTT GCTGGAGGAG GTGGCGCAGC AGTGCCATGG CCCCATCACC 1140

CTGGATTTTG CAATCAACAA GCTCAAGATG GGGGGGTCCC TTCCTGGCTC CTACGTTCTC 1200

CGCCGCAGCC CCCAGGATTT CGACAGCTTC CTCCTCACTG TCTGTGTTCA GACGCCCCTG 1260

GGCCCTGATT ACAAGGGCTG CCTCATCCGG TGTGACCCCA CAGGAGCCTA CTCCCTGGCT 1320

GGCCTTGGCC GACCCCACAG TAGTCTGCGA GAGCTCCTGG CAGCCTGCTG GGATGGTGGG 1380

CTGCATGTGG ATGGGGTTGC ACTGAACCTT ACCTTCTGCT GCACCCCTAG ACCCAAAGAA 1440

AAGTCCAATC TGATTGTGGT CCGGAGAGGT TGCAGCCCAC CCACATCATC CCCCGTGCAG 1500

CCCCACTCAG GATGCCAGCT GAGTCAGATG ACATTTCACA AGATACCTGC TGACAGCTTG 1560

GAGTGGCATG AGAACCTGGG TCATGGATCC TTCACGAAGA TTTACCGGGG CTGTCGCCAC 1620

GAGGCCATGG ATGGGGAGCC CCGGAAGACA GAGGTGCTGC TCAAGGTGTT GGATGCCAAA 1680

CACAAGAACT GCATGGAGTC ATTCCTGGAA GCAGCAAGTT TGATGAGCCA AGTATCGTAC 1740

CAGCATCTCG TGTTGCTTCA TGGCGTGTGC ATGGCTGGAG ACAGCATCAT GGTGCAGGAA 1800

TTTGTACACC TGGGAGCACT GGACACGTAT CTACGCAAGT GTGGGCAGCT GGTGCCAGCC 1860

AGCTGGAAGC TGCAGGTGAT CAAACAGCTG GCCTATGCCC TCAACTATCT GGAGGACAAA 1920

GGCCTTCCCC ATGGCAATGT CTCAGCCCGG AAGGTGCTCC TGGCTCGGGA AGGGGCTGAG 1980

GGGAGCCCGC CCTTCATCAA GCTGAGTGAT CCCGGTGTCA GCCCCACTGT ACTAAGCCTG 2040

GAGATGCTCA CTGACAGGAT CCCCTGGGTA GCTCCTGAGT GTCTCCAGGA GGCCCGGACA 2100

CTTGGCTTGG AAGCTGACAA GTGGGGCTTC GGTGCCACAG TCTGGGAGGT GTTCAGTGGT 2160

GTCACGATGC CAATCAGTAC CCTGGATCCT GCCAAGAAGC TCCAGTTTTA TGAGGAACGG 2220

CAGCAACTGC CTGCCCCCAA GTGGATGGAG CTGGCCCTGC TGATCCAACA GTGCATGGCC 2280

TACGAGCCAG GCCACAGGCC CTCCTTCCGC GCCGTCATCC GTGACCTGAA CAACCTTATC 2340

ACGTCAGACT ATGAGCTCCT CTCGGACCCC ACACCTGGTG CCTTGGCACC CCGTGACGGG 2400

CTGTGGAATG GCGCCCAGCT CTATGCCTGC CAGGACCCTA CTATCTTTGA GGAGAGACAC 2460

CTGAAGTATA TCTCACAGCT GGGCAAGGGT AACTTTGGCA GCGTGGAACT ATGTCGCTAT 2520

GACCCGCTGG GAGACAACAC AGGTGCCCTG GTGGCCGTGA AGCAGCTGCA GCACAGTGGG 2580

CCAGACCAGC AGAGGGACTT CCAACGGGAG ATCCAGATCC TCAAAGCCCT GCACAGTGAC 2640

TTCATTGTCA AGTACCGTGG TGTCAGCTAT GGCCCAGGCC GTCAGAGCCT GCGGCTAGTC 2700

ATGGAGTACC TGCCCAGTGG CTGCCTGAGA GATTTCCTGC AGCGGCACCG CGCACGCCTC 2760

GGCGCCGGCC GCCTGCTCCT CTATGCTTCG CAGATCTGCA AGGGCATGGA GTATCTGGGC 2820

TCCTGCCGCT GCGTGCACCG CGACCTGGCA GCGCGTAACA TCTTGGTGGA GAGCGAGACG 2880

CACGTCAAGA TCGCCGACTT TGGCCTCGCC AAGCTGCTGC CGCTGGACAA AGACTATTAC 2940

GTCGTCCGCG AGCCAGGCCA GAGCCCCATT TTCTGGTACG CCCCGGAGTC CCTCTCAGAC 3000

AACATCTTCT CGCGCCAGTC GGACGTCTGG AGCTTCGGAG TCGTCCTGTA CGAGCTTTTC 3060

ACCTACAGTG ACAAGAGCTG CAGCCCCTCC GCCGAGTTCC TGCGGATGAT GGGTTGTGAG 3120

AGAGATATCC CGGCTCTTTG CCGCCTCCTG GACCTGCTGG CAGAGGGCCA GAGGCTGCCG 3180

GCGCCTCCAG CCTGCCCTGG AGAGGTTCAT GAGCTCATGA AGCTATGCTG GGCTCCTAGC 3240

CCGCAAGACC GGCCTACTTT CAGTGCC 3267

Domain Profile

S: 1     lkqiesLgkgtftkvfevredaegdsteeevalkvLkesgedisrdfkreaeilsqlshe  60

         lk+i++Lgkg+f++v+++r+d+ gd+t++ va+k+L++sg+d++rdf+re++il++l+++

Q: 821   LKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSD  880

         799*********************************************************

S: 61    hivklkgvcvaegen..rlVmeyvesGsLdiyLrkkkealslsslldvakqlakameYLe  118

         +ivk++gv++ +g++  rlVmey++sG+L+++L++++++l + +ll +a+q++k+meYL+

Q: 881   FIVKYRGVSYGPGRQslRLVMEYLPSGCLRDFLQRHRARLGAGRLLLYASQICKGMEYLG  940

         ************************************************************

S: 119   dkklvhrdvaarnvLveresnegtppfvklsdpglakavnqd.eYylvreerdsripwla  177

         + ++vhrd+aarn+Lve+e +      vk++d+glak+++ d +Yy+vre+++s+i+w+a

Q: 941   SCRCVHRDLAARNILVESETH------VKIADFGLAKLLPLDkDYYVVREPGQSPIFWYA  994

         *********************......*********************************

S: 178   peclseaknlstasdvWsFgvtlyellt.cskgesp....lrsesle.......rklell  225

         pe+ls++  +s++sdvWsFgv+lyel+t  +k++sp    lr++++e       r+l ll

Q: 995   PESLSDNI-FSRQSDVWSFGVVLYELFTySDKSCSPsaefLRMMGCErdipalcRLLDLL  1053

         ********.*******************999*****************************

S: 226   eekerlpkpk.cpaelaelmtnclsyepsqrpsFr  259

          e++rlp+p+ cp e++elm+ c++ +p++rp+F+

Q: 1054  AEGQRLPAPPaCPGEVHELMKLCWAPSPQDRPTFS  1088

         **********************************7

Domain Sequence
(FASTA)

LKYISQLGKG NFGSVELCRY DPLGDNTGAL VAVKQLQHSG PDQQRDFQRE IQILKALHSD 60

FIVKYRGVSY GPGRQSLRLV MEYLPSGCLR DFLQRHRARL GAGRLLLYAS QICKGMEYLG 120

SCRCVHRDLA ARNILVESET HVKIADFGLA KLLPLDKDYY VVREPGQSPI FWYAPESLSD 180

NIFSRQSDVW SFGVVLYELF TYSDKSCSPS AEFLRMMGCE RDIPALCRLL DLLAEGQRLP 240

APPACPGEVH ELMKLCWAPS PQDRPTFS 268

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Xenopus tropicalis"; ?>