EKS-RAN-00501

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00501

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	303.3	3.7E-90	807	994	188

Status

Unreviewed

Ensembl Protein

ENSRNOP00000062125

UniProt Accession

D3ZGA6;

Protein Name

Protein Synonyms/Alias

Protein Rps6kc1;

Gene Name

Rps6kc1

Gene Synonyms/Alias

Rps6kc1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000003767	ENSRNOP00000062125	ENSRNOT00000067017

Organism

Rattus norvegicus

Functional Description

Protein Length

1004

Protein Sequence
(FASTA)

MTSPWGHSAD LARFYTVTEP QRHPRGYTIY KVTARVVSRR NPEDVQEIIV WRRYSDFKKL 60

HRELWQIHRN AFRHSELFPP FAKGTVFGRF DKTVIEERRQ CAEDLLQFSA NIPALYNSKQ 120

LQDFFKGGII SDGSELIGPA EAYPDSLANT FSECGTEGFS SDSDLLSLTV DADSLAEVDD 180

GMASRQGSPS RAFGLSVSAD SSAVGAVASD IEPSKAEDRE SRSLFPSSLK PRLGRRDYLE 240

KAGELIKLAL KKEEEDDYEA ASDFYRKGVD LLLEGVQGAL SSRPPWNLRS PAEELKAFRV 300

LGVIDKVLLV MDTRTEQTFI LKGLRKSSEC SRNRKTIIPR CVPNMVCLHT YIISEESVFL 360

VLQHAEGGKL WSYISKFLNR SSRESLDIKE ARPPMPPRVR LQQPSASPQG SYSVESRGSD 420

TGSMLKVLPL KTSLTPSSQD DSNQEDDGQD SSPKWPDSGS SSEEECTAGY LTLCNEYGQE 480

KLDLTSLNEE SVMQPEGENA DSQAVRSFPA SLTADSASPS TQLKFFPGDE GLEAVCSPRT 540

SDSLRRSKNS PMEFFRIDSK DSTSELLGLD SGEKLHSLKP EPLKALFTLE DGDSPSQSFD 600

AGKSQGESEA QDSISRGSDD SVPVISFKEA ASEDVCSAEE GRPDLLVNLP GELQPTKETS 660

AVDPTKFSQA SIGRLEAPDV LCLRLSSEQC HDLGQEGPEE LSHPTEFRPG GVTPERSAQA 720

DLGVLFTATV DHSSSQDQFL FSSLHSESDR LGQVEGAVTS QDLQESLFHI ASPCSGAKED 780

SAHTDTATSE EVLLFTEPSK EGDSEAKVRS VGAGGAEKEV HQIFEDLDQR LAVSARLFIP 840

EGCIQRWAAE MVVALDALHR EGIVCRDLNP NNILLNDGGH IQLTYFSRWS EVEDLCDSDA 900

IARMYCAPEV GAVTEETEAC DWWSLGAVLF ELLTGKTLVE CHPAGINTHT TLNMPDCVSE 960

EARSLIQQLL QFNPMERLGA GVAGVEDIKS HPFFTPVDWA ELTR 1004

Nucleotide Sequence
(FASTA)

ATGACCTCTC CTTGGGGTCA CAGTGCGGAC CTGGCCCGCT TCTACACTGT CACCGAGCCC 60

CAGCGACACC CTAGGGGCTA CACGATCTAT AAGGTTACCG CACGGGTCGT TTCACGAAGA 120

AATCCGGAGG ACGTCCAGGA GATAATTGTG TGGAGAAGAT ACAGTGACTT TAAGAAGCTG 180

CACAGAGAGC TATGGCAGAT TCACAGGAAC GCATTTCGAC ACTCTGAGCT GTTTCCCCCG 240

TTTGCTAAAG GGACAGTGTT TGGGCGATTT GACAAAACCG TAATTGAGGA ACGACGTCAG 300

TGTGCTGAGG ACCTGCTACA GTTCTCTGCC AACATCCCTG CTCTGTACAA CAGCAAGCAG 360

CTCCAGGACT TCTTTAAGGG TGGGATAATT AGTGATGGCT CTGAGTTAAT TGGCCCTGCT 420

GAAGCTTACC CAGACTCCCT GGCCAACACC TTTTCTGAGT GTGGTACTGA AGGCTTCTCC 480

AGTGACAGTG ACCTCCTGTC CCTCACTGTT GATGCGGACT CTCTTGCCGA GGTAGATGAT 540

GGAATGGCTT CCCGTCAGGG TTCTCCCAGT AGAGCTTTTG GTCTGAGTGT GTCTGCGGAT 600

TCTTCGGCAG TAGGGGCTGT TGCTTCTGAC ATTGAACCAA GCAAAGCAGA AGACCGGGAA 660

AGCCGCAGCC TCTTCCCCAG CAGCTTAAAG CCAAGGCTTG GCAGGAGAGA TTACCTGGAG 720

AAGGCAGGGG AACTTATCAA ACTGGCCTTA AAGAAGGAGG AGGAAGATGA CTATGAAGCA 780

GCTTCTGACT TTTACAGGAA GGGTGTTGAT CTGCTCCTAG AAGGTGTACA AGGAGCACTA 840

AGTTCAAGGC CCCCTTGGAA CCTAAGGAGC CCTGCCGAGG AGCTGAAGGC CTTCAGAGTC 900

CTTGGGGTGA TTGACAAGGT TTTACTTGTA ATGGACACAA GGACAGAACA GACATTCATT 960

TTAAAAGGTC TCAGGAAAAG CAGCGAGTGC AGCAGGAACA GGAAGACCAT CATCCCCCGC 1020

TGTGTGCCTA ACATGGTGTG TCTGCACACA TACATCATCT CGGAGGAGTC GGTGTTTCTC 1080

GTGCTGCAGC ACGCCGAAGG TGGCAAACTC TGGTCATATA TCAGTAAATT TCTGAACAGA 1140

AGCTCTCGAG AAAGCTTGGA CATTAAGGAG GCGAGACCGC CCATGCCTCC TCGAGTGCGC 1200

CTGCAGCAGC CAAGTGCTAG TCCTCAGGGC AGCTACAGTG TTGAGTCCAG AGGGAGCGAC 1260

ACAGGGAGCA TGCTGAAGGT TCTGCCCCTG AAGACTAGCC TCACCCCGAG TTCTCAGGAC 1320

GATAGTAACC AGGAAGATGA TGGGCAGGAC AGCTCTCCCA AGTGGCCCGA TTCGGGCTCC 1380

AGCTCAGAGG AAGAGTGCAC AGCTGGCTAC TTAACGCTGT GCAACGAATA TGGGCAAGAA 1440

AAGCTTGACC TTACATCTTT GAATGAGGAG TCTGTCATGC AGCCTGAAGG GGAGAATGCT 1500

GATAGCCAAG CTGTTAGGAG CTTCCCAGCA TCCCTCACCG CTGACAGTGC AAGCCCCAGC 1560

ACCCAGCTCA AGTTCTTCCC TGGAGACGAG GGCCTAGAAG CAGTTTGTTC TCCTCGAACA 1620

TCTGATTCCC TCAGGAGGTC GAAAAACAGT CCTATGGAGT TCTTCCGAAT AGACAGTAAA 1680

GACAGCACAA GTGAGCTCTT GGGACTGGAT TCTGGTGAGA AATTACACAG TCTGAAACCA 1740

GAGCCTTTGA AAGCACTCTT TACCCTTGAA GATGGAGACA GTCCTTCCCA GAGTTTTGAT 1800

GCCGGCAAGA GCCAGGGAGA GAGTGAAGCT CAGGACTCCA TCAGCAGGGG CTCAGATGAC 1860

TCCGTCCCGG TTATCTCATT TAAAGAGGCT GCCTCTGAGG ATGTCTGTAG TGCTGAGGAA 1920

GGGAGGCCTG ACCTTCTTGT GAATCTACCT GGTGAACTGC AGCCAACCAA AGAGACTTCA 1980

GCAGTGGACC CTACTAAGTT TTCACAGGCC AGCATAGGCA GGCTGGAAGC CCCGGATGTG 2040

TTGTGCCTCA GGCTGAGTTC TGAACAGTGC CATGACCTGG GACAAGAAGG CCCAGAGGAA 2100

CTGAGCCATC CCACTGAATT CCGTCCTGGT GGTGTGACCC CAGAGCGCAG TGCTCAGGCA 2160

GATCTTGGGG TGTTGTTCAC GGCTACAGTT GATCACAGCA GCTCACAAGA CCAGTTTCTG 2220

TTTTCCAGCT TGCATTCAGA GTCTGACAGG CTGGGGCAGG TGGAGGGAGC GGTCACTTCA 2280

CAGGACTTGC AAGAAAGCCT ATTCCACATT GCTAGTCCAT GCTCAGGTGC TAAAGAAGAC 2340

AGCGCACACA CAGACACTGC CACGTCTGAG GAAGTGCTGC TGTTCACAGA GCCGAGCAAA 2400

GAAGGAGACT CGGAGGCCAA GGTGCGGAGT GTGGGAGCCG GGGGAGCGGA GAAGGAAGTC 2460

CATCAGATCT TCGAGGACCT GGACCAGCGA CTAGCAGTAA GCGCCAGGCT CTTCATCCCA 2520

GAGGGCTGCA TTCAAAGATG GGCAGCAGAG ATGGTGGTAG CCCTGGACGC CTTGCATAGA 2580

GAGGGGATTG TGTGCCGAGA TCTGAACCCA AACAACATCT TATTGAATGA TGGAGGACAC 2640

ATTCAGCTAA CGTATTTTAG CAGGTGGAGT GAGGTTGAAG ATCTCTGTGA CAGCGACGCC 2700

ATAGCGAGAA TGTACTGCGC CCCAGAGGTT GGAGCAGTCA CAGAAGAAAC TGAAGCCTGT 2760

GATTGGTGGA GCCTGGGTGC TGTCCTCTTC GAACTTCTCA CTGGCAAGAC ATTGGTGGAA 2820

TGCCACCCAG CGGGAATAAA TACTCACACT ACTTTGAACA TGCCAGATTG TGTTTCTGAA 2880

GAGGCCCGCT CACTCATCCA ACAGCTCCTG CAGTTCAACC CTATGGAGCG TCTGGGTGCA 2940

GGAGTGGCCG GTGTTGAAGA TATCAAATCT CACCCGTTCT TCACCCCTGT GGATTGGGCA 3000

GAACTGACAA GATGA 3015

Domain Profile

S: 174   rirregqnsspssskeiklvsedadkslealsrgldkalqsvdkalslrravwslpEeli  233

         ++r+ g     ++ ke+++++ed+d++l++++r                    ++pE++i

Q: 807   KVRSVG---AGGAEKEVHQIFEDLDQRLAVSAR-------------------LFIPEGCI  844

         333322...234455555555555555555555...................67******

S: 234   kqWaaelvvaleaLHeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnl  293

         ++Waae+vval+aLH+eg+++rDln++niLl++ Gh++ltYf+rwseve+ c+++a++++

Q: 845   QRWAAEMVVALDALHREGIVCRDLNPNNILLNDGGHIQLTYFSRWSEVEDLCDSDAIARM  904

         ************************************************************

S: 294   ysAPEvgaiselteasDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkd  353

         y+APEvga++e+tea+DwWslGa+L+elLtGk+l+e+hP+gi++ht+l++P++vSeeA++

Q: 905   YCAPEVGAVTEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPDCVSEEARS  964

         ************************************************************

S: 354   LleeLLqfePalRlGaGeagvdelkaHPFF  383

         L+++LLqf+P++RlGaG+agv+++k+HPFF

Q: 965   LIQQLLQFNPMERLGAGVAGVEDIKSHPFF  994

         *****************************9

Domain Sequence
(FASTA)

KVRSVGAGGA EKEVHQIFED LDQRLAVSAR LFIPEGCIQR WAAEMVVALD ALHREGIVCR 60

DLNPNNILLN DGGHIQLTYF SRWSEVEDLC DSDAIARMYC APEVGAVTEE TEACDWWSLG 120

AVLFELLTGK TLVECHPAGI NTHTTLNMPD CVSEEARSLI QQLLQFNPME RLGAGVAGVE 180

DIKSHPFF 188

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013