EKS-RAN-00473

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00473

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	438.4	1.3E-131	26	308	283

Status

Unreviewed

Ensembl Protein

ENSRNOP00000009325

UniProt Accession

B1WC76;

Protein Name

Protein Synonyms/Alias

Mapk11 protein; Protein Mapk11;

Gene Name

Mapk11

Gene Synonyms/Alias

Mapk11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000006984	ENSRNOP00000009325	ENSRNOT00000009325

Organism

Rattus norvegicus

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

MSGPRAGFYR QELNKTVWEV PQRLQGLRPV GSGAYGSVCS AYDARLRQKV AVKKLSRPFQ 60

SLIHARRTYR ELRLLKHLKH ENVIGLLDVF TPATSIEDFS EVYLVTTLMG ADLNNIVKCQ 120

ALSDEHVQFL VYQLLRGLKY IHSAGIIHRD LKPSNVAVNE DCELRILDFG LARQADEEMT 180

GYVATRWYRA PEIMLNWMHY NQTVDIWSVG CIMAELLQGK ALFPGNDYID QLKRIMEVVG 240

TPSPEVLAKI SSEHARTYIQ SLPPMPQKDL SSVFHGANPL AVDLLGRMLV LDSDQRVSAA 300

EALAHAYFSQ YHDPDDEPEA EPYDESVEAK ERTLEEWKEL TYQEVLSFKP LETSQLPGTH 360

EIEQ 364

Nucleotide Sequence
(FASTA)

ATGTCGGGTC CGCGCGCGGG ATTCTACCGG CAAGAGCTGA ACAAAACAGT ATGGGAGGTG 60

CCGCAGCGGC TGCAGGGCCT ACGCCCGGTG GGCTCCGGCG CCTACGGCTC GGTCTGTTCG 120

GCCTACGACG CACGGCTGCG CCAGAAGGTG GCTGTGAAGA AGCTGTCTCG CCCTTTCCAA 180

TCGCTGATCC ACGCGAGGAG GACATACCGT GAGCTACGCC TACTCAAACA CCTGAAGCAC 240

GAGAACGTCA TAGGACTTTT GGACGTCTTC ACGCCGGCCA CATCCATCGA GGATTTCAGC 300

GAAGTGTACC TCGTGACCAC CCTGATGGGC GCTGACCTGA ATAACATCGT CAAGTGTCAG 360

GCCCTGAGCG ATGAGCATGT TCAGTTCCTT GTCTACCAGC TGCTGCGTGG GCTGAAGTAT 420

ATCCACTCGG CGGGCATCAT CCACCGGGAC CTGAAGCCCA GCAATGTAGC AGTGAATGAG 480

GACTGCGAGC TGAGGATCCT GGACTTTGGG CTGGCACGCC AGGCTGATGA GGAGATGACT 540

GGATATGTGG CCACACGGTG GTACCGGGCT CCAGAGATCA TGCTGAACTG GATGCACTAC 600

AACCAGACAG TGGACATCTG GTCTGTGGGC TGCATCATGG CTGAGCTGCT CCAAGGAAAG 660

GCCCTCTTTC CTGGAAATGA CTACATCGAC CAGCTGAAGC GGATCATGGA GGTGGTGGGC 720

ACACCCAGCC CTGAGGTTCT GGCAAAGATA TCCTCGGAGC ATGCCCGGAC ATACATCCAG 780

TCTCTGCCTC CCATGCCCCA GAAGGACCTC AGCAGTGTCT TCCATGGGGC CAACCCTCTG 840

GCTGTAGACC TCCTTGGAAG AATGCTGGTG CTAGACAGTG ACCAGAGAGT CAGTGCGGCC 900

GAAGCCTTGG CCCATGCATA CTTCAGCCAG TACCATGACC CTGACGACGA GCCAGAGGCC 960

GAGCCCTATG ATGAAAGTGT TGAGGCCAAG GAGCGCACCC TGGAGGAGTG GAAGGAGCTT 1020

ACTTACCAGG AAGTCCTTAG CTTCAAGCCC CTGGAAACAT CGCAGCTCCC TGGCACCCAT 1080

GAAATTGAGC AGTGA 1095

Domain Profile

S: 3     slkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiik  62

          l+p+g+Gayg v+sa+d+r +++va+kklsrpfq+ ++a+rt+REl+llk+lkheN+i

Q: 26    GLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIG  85

         5799********************************************************

S: 63    lldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHsan  122

         lldvftp++++e++++vYlvt+lm++dL++++k q lsdeh+++l+yq+lrglky+Hsa+

Q: 86    LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAG  145

         ************************************************************

S: 123   viHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkeyt  182

         +iHrDlKPsN++vnedcel+ildFGlar+ad+e    +t+yvatrwYraPei+l++++y+

Q: 146   IIHRDLKPSNVAVNEDCELRILDFGLARQADEE----MTGYVATRWYRAPEIMLNWMHYN  201

         ********************************9....***********************

S: 183   kavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyiks  242

         ++vDiWsvGCI+aEll+gk lfpg+d+idql++i+ev+gtps e+l+ki+se+ar+yi+s

Q: 202   QTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQS  261

         ************************************************************

S: 243   lpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         lp++++kd++++f+ a++ a+dLl ++Lvld+d+R+s++eaL+h Y+

Q: 262   LPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYF  308

         *********************************************96

Domain Sequence
(FASTA)

GLRPVGSGAY GSVCSAYDAR LRQKVAVKKL SRPFQSLIHA RRTYRELRLL KHLKHENVIG 60

LLDVFTPATS IEDFSEVYLV TTLMGADLNN IVKCQALSDE HVQFLVYQLL RGLKYIHSAG 120

IIHRDLKPSN VAVNEDCELR ILDFGLARQA DEEMTGYVAT RWYRAPEIML NWMHYNQTVD 180

IWSVGCIMAE LLQGKALFPG NDYIDQLKRI MEVVGTPSPE VLAKISSEHA RTYIQSLPPM 240

PQKDLSSVFH GANPLAVDLL GRMLVLDSDQ RVSAAEALAH AYF 283

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>