EKS-RAN-00401

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00401

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	369.7	1.3E-110	362	621	260

Status

Unreviewed

Ensembl Protein

ENSRNOP00000011406

UniProt Accession

B5DF98;

Protein Name

Protein Synonyms/Alias

Map3k3 protein; Mitogen activated protein kinase kinase kinase 3 (Predicted); Protein Map3k3;

Gene Name

Map3k3

Gene Synonyms/Alias

Map3k3; Map3k3_predicted; rCG_32739;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000008441	ENSRNOP00000011406	ENSRNOT00000011406

Organism

Rattus norvegicus

Functional Description

Protein Length

626

Protein Sequence
(FASTA)

MDEQEALDSI MKDLVALQMS RRPRVSGYET MKNKDTGHPN RQSDVRIKFE HNGERRIIAF 60

SRPVRYEDVE HKVTTVFGQP LDLHYMNNEL SILLKNQDDL DKAIDILDRS ASMKSLRILL 120

LSQDRNHTSS SPHSGVSRQV RVKPSQSAGD INTIYQAPEP RSRHLSVSSQ NPGRSSPPPG 180

YVPERQQHIA RQGSYTSINS EGEFIPETSE QCMLDPLSSA ENSLSGSCQS LDRSADSPSF 240

RKSQMSRARS FPDNRKECSD RETQLYDKGV KGGTYPRRYH VSVHHKDYND GRRTFPRIRR 300

HQGNLFTLVP SSRSLSTNGE NMGAAVQYLD PRGRLRSADS ENALTVQERS VPTKSPSAPI 360

NWRRGKLLGQ GAFGRVYLCY DVDTGRELAS KQVQFDPDSP ETSKEVSALE CEIQLLKNLQ 420

HERIVQYYGC LRDRAEKILT IFMEYMPGGS VKDQLKAYGA LTESVTRKYT RQILEGMSYL 480

HSNMIVHRDI KGANILRDSA GNVKLGDFGA SKRLQTICMS GTGMRSVTGT PYWMSPEVIS 540

GEGYGRKADV WSLGCTVVEM LTEKPPWAEY EAMAAIFKIA TQPTNPQLPS HISEHGRDFL 600

RRIFVEARQR PSAEELLTHH FAQLVY 626

Nucleotide Sequence
(FASTA)

ATGGATGAAC AAGAGGCATT AGACTCAATC ATGAAGGACC TGGTGGCCCT CCAGATGAGC 60

CGACGTCCCC GGGTGTCTGG ATATGAGACC ATGAAGAACA AGGACACAGG TCACCCAAAC 120

AGGCAGAGTG ACGTCAGAAT CAAGTTTGAA CACAATGGGG AGAGACGAAT TATAGCATTC 180

AGCCGGCCTG TGAGATATGA AGATGTGGAA CACAAGGTGA CAACGGTCTT TGGGCAGCCT 240

CTTGATTTGC ATTATATGAA TAATGAGCTC TCCATCCTGT TGAAAAACCA AGATGATCTC 300

GATAAAGCAA TTGACATTTT GGATAGAAGC GCGAGTATGA AAAGCCTTAG GATACTACTG 360

TTATCCCAAG ACAGAAACCA TACTAGTTCC TCTCCCCACT CTGGAGTGTC CAGGCAGGTT 420

CGGGTCAAGC CTTCCCAGTC TGCAGGGGAT ATAAATACCA TCTACCAAGC TCCTGAGCCC 480

AGAAGCAGGC ACCTCTCTGT CAGCTCCCAG AACCCTGGCC GAAGCTCTCC TCCCCCTGGT 540

TATGTACCTG AGCGACAACA GCACATTGCC CGGCAGGGAT CATATACGAG CATCAATAGT 600

GAAGGTGAAT TCATCCCAGA GACCAGCGAG CAGTGCATGC TAGATCCCCT GAGCAGTGCC 660

GAAAATTCCT TGTCAGGAAG CTGCCAATCC TTGGACAGGT CAGCAGACAG CCCATCTTTC 720

AGGAAATCAC AAATGTCCCG AGCCCGGAGC TTCCCAGACA ACAGAAAGGA ATGCTCGGAT 780

CGGGAGACCC AGCTCTATGA TAAAGGAGTT AAAGGCGGAA CCTATCCCAG GCGTTACCAT 840

GTATCTGTGC ATCATAAAGA CTACAATGAT GGCAGAAGAA CGTTTCCCCG AATACGACGG 900

CACCAGGGCA ACCTATTCAC TCTGGTGCCC TCAAGTCGCT CCTTGAGCAC AAATGGCGAG 960

AACATGGGTG CCGCTGTGCA GTACTTGGAC CCCCGCGGGC GCCTACGGAG TGCAGACAGT 1020

GAAAATGCCC TCACTGTGCA GGAAAGAAGT GTGCCAACCA AGTCTCCTAG TGCTCCCATC 1080

AATTGGCGTC GGGGGAAGCT CCTGGGTCAA GGTGCCTTCG GCAGGGTCTA CTTATGCTAT 1140

GATGTGGACA CAGGACGTGA ACTTGCTTCT AAGCAGGTTC AGTTTGACCC AGATAGTCCT 1200

GAGACTAGCA AGGAGGTGAG TGCTCTGGAG TGCGAGATCC AGTTGCTGAA GAACTTGCAG 1260

CATGAGCGCA TCGTGCAGTA CTATGGCTGC CTGCGGGACC GTGCTGAGAA GATCCTCACC 1320

ATCTTTATGG AGTATATGCC AGGGGGCTCT GTAAAAGACC AGTTGAAGGC CTACGGAGCT 1380

CTGACGGAGA GTGTGACCCG CAAGTATACA CGGCAGATCC TGGAGGGCAT GTCCTACCTG 1440

CACAGCAACA TGATCGTGCA TCGTGACATC AAGGGAGCCA ATATCCTCCG AGACTCGGCT 1500

GGGAATGTGA AGCTTGGGGA TTTTGGGGCC AGCAAACGCC TGCAAACCAT CTGCATGTCA 1560

GGGACAGGCA TGCGCTCTGT CACTGGCACA CCCTACTGGA TGAGTCCTGA AGTCATCAGT 1620

GGCGAGGGCT ATGGAAGAAA GGCAGATGTG TGGAGCCTGG GCTGTACCGT GGTGGAGATG 1680

CTGACAGAGA AACCACCTTG GGCAGAGTAT GAAGCTATGG CTGCCATTTT CAAGATTGCC 1740

ACCCAGCCTA CCAATCCTCA GCTGCCCTCT CACATCTCAG AACACGGCAG GGACTTCCTG 1800

AGGCGCATAT TTGTGGAAGC TCGTCAGAGA CCCTCGGCTG AGGAGCTGCT CACACACCAC 1860

TTTGCACAGC TAGTGTACTG A 1881

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w++++++g+G+fg+vy+++dvdtg+ la K+v+++p++ +++kev+al++Ei+llk+l+H

Q: 362   WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQH  421

         899*********************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  ++ e+ l+if+Ey++gGs++++l++yg+l+esv++kyt+qileg++yLH

Q: 422   ERIVQYYGClrDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLH  481

         *********76677889*******************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++++ + ++s+tGt+++m+PEvi++

Q: 482   SNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG  541

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaD+Wslgc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p+++se+g+d

Q: 542   E--GYGRKADVWSLGCTVVEMLTEKPPWAEY-EAMAAIFKIATQPTNPQLPSHISEHGRD  598

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhef  262

         fl++++ +++++rpsaeeLL+h+f

Q: 599   FLRRIF-VEARQRPSAEELLTHHF  621

         ******.8999***********99

Domain Sequence
(FASTA)

WRRGKLLGQG AFGRVYLCYD VDTGRELASK QVQFDPDSPE TSKEVSALEC EIQLLKNLQH 60

ERIVQYYGCL RDRAEKILTI FMEYMPGGSV KDQLKAYGAL TESVTRKYTR QILEGMSYLH 120

SNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICMSG TGMRSVTGTP YWMSPEVISG 180

EGYGRKADVW SLGCTVVEML TEKPPWAEYE AMAAIFKIAT QPTNPQLPSH ISEHGRDFLR 240

RIFVEARQRP SAEELLTHHF 260

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>