EKS-RAN-00349

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00349

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	300.9	9.7E-90	11	321	311

Status

Unreviewed

Ensembl Protein

ENSRNOP00000051998

UniProt Accession

D4A6D6;

Protein Name

Protein Synonyms/Alias

Protein kinase LYK5, isoform CRA_a; STE20-related kinase adapter protein alpha;

Gene Name

Strada

Gene Synonyms/Alias

Strada; Lyk5; rCG_34755;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000008637	ENSRNOP00000011894	ENSRNOT00000011894
ENSRNOG00000008637	ENSRNOP00000051998	ENSRNOT00000055125

Organism

Rattus norvegicus

Functional Description

Protein Length

373

Protein Sequence
(FASTA)

MSSFLPEGGC YELLSVIGKG FEDLMTVNLA RYKPTGEYVT VRRINLEACS NEMVTFLQGE 60

LHVSKLFSHP NIVPYRATFI ADNELWAVTS FMAYGSAKDL IGTHFMDGMS ELAIAYILQG 120

VLKALDYIHH MGYVHRSVKA SHILISTDGK VYLSGLRSNL SMISHGQRQR AVHDFPKYSI 180

KVLPWLSPEV LQQNLQGYDA KSDIYSVGIT ACELANGHVP FKDMPATQML LEKLNGTVPC 240

LLDTSTIPAE ELTMSPSRSI ANPGLNDSLA AGSLRPANGD SPSHPYHRTF SPHFHNFVEQ 300

CLQRNPDARP NASTLLNHSF FKQIKRRASE ALPELLRPVT PITSFEGSQS QDHSGILGLV 360

TNLEDLEVDD WEF 373

Nucleotide Sequence
(FASTA)

ATGAGTAGCT TTCTGCCAGA GGGCGGGTGT TACGAGCTGC TCTCCGTCAT AGGCAAAGGG 60

TTTGAGGACT TGATGACAGT GAATTTAGCC AGGTACAAAC CAACAGGAGA GTATGTGACA 120

GTACGAAGGA TCAACCTAGA AGCTTGTTCC AATGAGATGG TGACGTTCTT GCAGGGGGAG 180

CTTCATGTCT CTAAACTCTT CAGCCATCCC AATATCGTGC CGTATCGAGC CACCTTCATC 240

GCAGACAACG AGCTGTGGGC CGTCACATCA TTCATGGCGT ACGGTTCTGC AAAGGATCTC 300

ATTGGCACAC ACTTCATGGA CGGCATGAGT GAACTGGCGA TTGCGTACAT CCTGCAGGGG 360

GTGCTAAAGG CCTTAGACTA CATCCATCAC ATGGGCTATG TGCACAGGAG TGTCAAGGCC 420

AGCCACATTC TGATCTCCAC GGATGGGAAG GTCTACCTGT CTGGCTTACG CAGCAACCTT 480

AGCATGATCA GTCATGGACA ACGGCAGCGT GCGGTCCATG ATTTCCCCAA ATATAGCATC 540

AAGGTCCTGC CTTGGCTCAG CCCAGAAGTC CTCCAGCAGA ATCTTCAGGG TTATGACGCC 600

AAGTCTGATA TCTACAGTGT GGGAATCACA GCGTGCGAAC TAGCCAATGG CCATGTCCCC 660

TTCAAAGACA TGCCTGCTAC TCAGATGCTG CTAGAGAAAC TTAATGGCAC CGTGCCCTGC 720

CTGCTGGACA CCAGCACCAT CCCTGCTGAG GAGCTGACCA TGAGTCCCTC CCGCTCCATT 780

GCCAACCCTG GCCTGAATGA CAGCCTGGCC GCTGGTAGCC TCCGGCCTGC CAATGGTGAC 840

TCCCCTTCCC ACCCCTACCA CCGAACCTTC TCACCCCATT TCCACAACTT TGTGGAGCAG 900

TGCCTTCAGC GCAACCCTGA TGCAAGGCCA AACGCCAGCA CCCTCCTGAA CCACTCCTTC 960

TTCAAGCAGA TCAAGCGACG TGCTTCCGAG GCTTTACCTG AGTTGCTCCG CCCAGTCACT 1020

CCCATCACCA GCTTCGAGGG CAGCCAGTCT CAGGATCATA GTGGAATCTT AGGCCTGGTG 1080

ACAAACCTGG AAGACCTGGA GGTGGATGAC TGGGAGTTCT GA 1122

Domain Profile

S: 1     yelleeigkG..algkvylarekktgelvaikkinlekq..ekleelqkeisvlkklkhp  56

         yell++igkG  +l++v+lar k+tge+v++++inle++  e+++ lq e++v+k ++hp

Q: 11    YELLSVIGKGfeDLMTVNLARYKPTGEYVTVRRINLEACsnEMVTFLQGELHVSKLFSHP  70

         899*******999**************************9999*****************

S: 57    niveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHs  116

         niv y ++f++++elw v++++a+Gs++dl+ ++++++++E +iayil++vlkaL+y+H+

Q: 71    NIVPYRATFIADNELWAVTSFMAYGSAKDLIGTHFMDGMSELAIAYILQGVLKALDYIHH  130

         ************************************************************

S: 117   kkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtp.......ywmAPEv  169

         ++++Hr++ka++iL++++g+V+Ls+++++ ++ ++++++++v+++p       +w++PEv

Q: 131   MGYVHRSVKASHILISTDGKVYLSGLRSNLSMISHGQRQRAVHDFPkysikvlPWLSPEV  190

         **********************************************99988888******

S: 170   iaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk......  223

         ++q+ +gYd+k+Di+s+GIta+ela+g++Pfkd++++++ll++l++++p l ++

Q: 191   LQQNLQGYDAKSDIYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTstipae  250

         *************************************************88666678888

S: 224   .....................................kkfskefkefvekclqknpekRp  246

                                              ++fs++f++fve+clq+np++Rp

Q: 251   eltmspsrsianpglndslaagslrpangdspshpyhRTFSPHFHNFVEQCLQRNPDARP  310

         888899999999999999********9999999999999*********************

S: 247   sasellkhkFl  257

         +as+ll+h+F+

Q: 311   NASTLLNHSFF  321

         **********7

Domain Sequence
(FASTA)

YELLSVIGKG FEDLMTVNLA RYKPTGEYVT VRRINLEACS NEMVTFLQGE LHVSKLFSHP 60

NIVPYRATFI ADNELWAVTS FMAYGSAKDL IGTHFMDGMS ELAIAYILQG VLKALDYIHH 120

MGYVHRSVKA SHILISTDGK VYLSGLRSNL SMISHGQRQR AVHDFPKYSI KVLPWLSPEV 180

LQQNLQGYDA KSDIYSVGIT ACELANGHVP FKDMPATQML LEKLNGTVPC LLDTSTIPAE 240

ELTMSPSRSI ANPGLNDSLA AGSLRPANGD SPSHPYHRTF SPHFHNFVEQ CLQRNPDARP 300

NASTLLNHSF F 311

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0030295	; F:protein kinase activator activity
GO:0004672	; F:protein kinase activity
GO:0032147	; P:activation of protein kinase activity
GO:0006611	; P:protein export from nucleus

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013