EKS-RAN-00088

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-RAN-00088

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.9	2.4E-133	2292	2617	326

Status

Unreviewed

Ensembl Protein

ENSRNOP00000043760

UniProt Accession

D3Z822;

Protein Name

Protein Synonyms/Alias

Protein Atr;

Gene Name

Atr

Gene Synonyms/Alias

Atr;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000010027	ENSRNOP00000043760	ENSRNOT00000049967

Organism

Rattus norvegicus

Functional Description

Protein Length

2642

Protein Sequence
(FASTA)

MGDHGLELAS MIPALRELGS ATPEEYNTVV QKPRQILCQF IDRILTDVNV VALELVKKTD 60

TQPTSVMLLD FIQHIMKSSP LMFVNVNGSQ GQNEAKDSCI EFSHWIITRL LRIAATPSCH 120

MLHKKICEVI CSLLFLFKSK NPAIFGVLTR ELLYLFEDLI YLHKRNAVGD VMEWPVVVSR 180

FLSRLDEHMG CLQPAPLQFM NMQNVEFIEV TLLMVLIHIV PTVFFRRQEL LLWQIGCALL 240

EHGSPKIRSL AISLLTELFE LGGLPAQPAS TFFSLFLELL QHLIGMDADQ LKLYEEPLSK 300

LVKTLFPFEA EAYRNIEPVY LNVLLEKLRV MFEDRVLMRL KSDLLKAALC HLLQYFLTFV 360

PAGYESALQV RKVYVTDICR ALVDVLGVQT HVGYLLGPFY AALKMESTEI IERIQCQAQQ 420

ENLRGSNDGV SPKRRRLSSS LSSYKRPSRQ SEEINHVDMD KKSILWNVLK QKAESLQISL 480

ECGTLKNSVA EALEGITIVL QLTALCTVHC SHQDMDGHNA KDCQHKYKKK PPVVITWMSL 540

DFYTKVLKSC KSLLESVQKH ELELVIDSVV RIYDALMYIQ VKSSFQDHVL EELCGMLSLP 600

WIYSYSDDNS LKMTTFATNL LRLSQRVWES YSPQAQSQCV FLLTLFPKRI FLDWRTTVYN 660

WALKSSHEVI RTSCVKGFFI LLQQENSCNQ IPKMLIDRVK DDSHVVKKEF ASVLGQLVCT 720

LHGMFYLTSS SVEPFFGPVD LFCKNLKATS QHECSSSQVK ASVCKPFLFL LTKNTPSPVK 780

LAFIDNLHHL CKHLDFQEDE TEVKAVLGTL LNLMEDPDKD VRIAFSGNIK YILESLNSED 840

GFIKELFVLR MKEAYTHAQI SRSNELKDTL ILTTGDIGRA AKGDLIPFAL LHLLHCLLSK 900

SASVSGAAYT EIRALVAAKS VKLQNFFSQY KKPICQFLVE SLHSSQMTAL PSTPCQTAEM 960

RKQHVAHHRE MALNTLSEIA NVFDFPDLNR FLTRTLQVLL PDLAAKASPA ASALIRTLGK 1020

QLNVNRREIL INNFKYIFSH LVCSCSKDEL ERALHYLKNE TEIELGSLLR QDFQGLHNEL 1080

LLRIGEHYQQ VFNGLSILAS FASSDDPYQG PRDITSPELM ADYLQPKLLG ILAFFNMQLL 1140

SSSVGIEDKK MALTSLMSLM KLMGPKHVSS VRVKMMTTLR TGLRFKDDFP ELCCRAWDCF 1200

VRCLDHAYLG PLLSHVIVAL LPLIQMQPKE TAAIFHYLII ENRVAVQDFL HEIYFLPDHP 1260

ELEKIKAVLQ EYRKETSEST DLQTTLQLSM KAIQHENVDV RIHALTSLKE TLYKNQEKLI 1320

KYATDSETVE PVISQLVTVI LKGCQDANSQ ARLLCGECLG ELGAIDPGRL DFSTTETQGK 1380

DFTFVTGVED LSFAYGLLME LTRAYLAYAD NSRAQDSAAY AIQELLSIYD CREMQSNGPG 1440

HQLWKRFPEH VREILEPHLN TRYKSSQKST DWSGVTKPIY LSKLGNNFAE WSSSWAGYLI 1500

TKVRDNLASK IFTCCSIMMK HDFKVTIYLL PHILVYVLLG CSQEDQQEVY AEIMAVLKHD 1560

DQHAISTQDS ASDLCQLSTQ TVFSMLDHLT QWARHKFQAL NAEKLAQNKP KGGKVNYPVS 1620

SVNFEDYQSV TRFLDLIPQD TLAVASFRSK AYTRAVMHFE SFITEKKQNI QKHLGFLQKL 1680

YAAMHEPDGV AGVSAIRKAE PSLKEQILEH ESIGLLRDAT ACYDRAIQLE PDQIIHYHGV 1740

VKSMLGLGQL STVITQVNGV HANRSEWTDE LNTYRVEAAW KLSQWDLVEN YLAADGKSTT 1800

WSVRLGQLLL SAKKRDTTAF YDTLKLVRAE QIVPLSAASF ERGSYQRGYE FIVRLHMLCE 1860

LEHSLKPLFH KFPGDSCNED SLNWAARLEM TQNSYRAKEP ILALRRALLS LNKRPDYNEM 1920

VGECWLQSAR VARKAGHHQT AYNALLNAGE SRLAELYVER AKWLWSKGDV HQALIVLQKG 1980

VELCFPENKS PTESKHMLIH GRATLLVGRF MEETANFESN AIMKKYKDVT LFLPEWEDGH 2040

FYLAKYYDKL MPMVTDNKME KQGDLIRYIV LHFGRSLQYG NQFIYQSMPR MLSLWLDFGA 2100

KAYEWEKGGR SDRLQMRNDL AKINSVLTEH TNRLAPYQFL TAFSQLISRI CHSHDEVFVV 2160

LMEIIAKVFL AYPQQAMWMM TAVSKSSYPM RVNRCKEILT KAIHMKKSLE KFVGDATRLT 2220

DKLLELCNKS VDGSNSTLSM STHFKMLKKL VEDPTFSEIL IPLQSVMIPT LPSILGAHAN 2280

HDPFPGHWAY LAGFDDVVEI LSSLQKPKKI SLKGSDGKFY IMMCKPKDDL RKDCRLMEFN 2340

SLINKSLRKD AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRPILTK LYKEKGVYMT 2400

GKELRQCMLP KSAALSEKLK VFQEILLPRH PPVFHEWFLR TFPDPTSWYS SRSAYCRSTA 2460

VMSMVGYILG LGDRHGENIL FDSFTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG 2520

MGPMGTEGLF RRACEVTLRL MRDQREPLMS VLKTFLHDPL VEWSKPVKGH SKAPPNETGE 2580

VVNEKAKTHV LDIEQRLQGV IKTRNRVTGL PLSIEGHVHY LIQEATDENL LCQMYLGWTP 2640

YM 2642

Nucleotide Sequence
(FASTA)

ATGGGTGACC ACGGGCTGGA GCTGGCGTCC ATGATTCCCG CCCTGCGGGA GTTGGGCAGT 60

GCTACTCCAG AGGAATATAA TACTGTTGTG CAGAAACCAA GACAAATTCT CTGCCAATTC 120

ATTGACCGAA TACTTACAGA TGTAAATGTT GTTGCTCTCG AACTTGTAAA GAAAACTGAC 180

ACTCAGCCGA CCTCTGTGAT GTTACTTGAT TTTATCCAGC ACATCATGAA GTCTTCTCCA 240

CTTATGTTTG TAAATGTGAA TGGAAGCCAG GGCCAAAATG AGGCCAAAGA CAGTTGTATT 300

GAATTCAGTC ATTGGATCAT TACAAGACTT TTACGGATTG CAGCAACTCC ATCCTGCCAC 360

ATGCTACACA AGAAAATATG TGAAGTTATC TGCTCATTAT TATTTCTTTT TAAAAGCAAG 420

AATCCTGCTA TTTTTGGGGT ACTCACAAGA GAATTACTTT ATCTTTTTGA AGACTTGATT 480

TACCTCCACA AAAGAAATGC AGTGGGTGAT GTTATGGAAT GGCCAGTGGT TGTCAGTCGA 540

TTTTTAAGCC GATTGGATGA ACACATGGGA TGTTTACAGC CAGCTCCTTT GCAGTTCATG 600

AACATGCAAA ATGTAGAATT TATTGAAGTC ACTTTATTAA TGGTTCTTAT TCATATTGTT 660

CCAACTGTGT TTTTTAGACG ACAAGAATTG TTACTGTGGC AGATTGGCTG TGCTCTGCTA 720

GAGCATGGTA GTCCCAAGAT CAGATCTTTA GCAATTAGCC TTTTAACTGA GCTCTTTGAG 780

CTGGGAGGAT TACCAGCACA GCCAGCCAGC ACCTTTTTCA GCCTATTTTT GGAGTTGCTA 840

CAACACCTTA TAGGAATGGA TGCTGACCAA CTGAAATTGT ATGAAGAGCC ATTGTCAAAG 900

CTGGTAAAAA CACTGTTCCC CTTTGAGGCA GAGGCTTATA GAAATATTGA ACCTGTTTAC 960

TTAAATGTGC TGCTGGAAAA ACTCCGAGTC ATGTTTGAAG ATCGCGTGCT CATGCGGCTC 1020

AAGTCTGATT TGCTGAAAGC AGCTCTGTGC CATTTACTGC AGTATTTCCT CACATTTGTG 1080

CCAGCGGGGT ATGAGTCGGC GTTACAGGTC AGGAAGGTTT ATGTGACTGA TATTTGTAGA 1140

GCTCTTGTAG ATGTCCTCGG AGTTCAGACA CATGTGGGGT ATTTGTTGGG ACCATTTTAT 1200

GCAGCCTTGA AAATGGAAAG TACGGAAATT ATTGAGAGAA TTCAATGTCA AGCTCAACAG 1260

GAGAATCTCC GTGGTAGTAA TGATGGTGTG TCACCAAAGA GGCGTAGACT CAGCTCCTCT 1320

CTCAGCTCTT ACAAAAGGCC ATCCAGACAG TCTGAAGAAA TTAATCATGT GGATATGGAC 1380

AAAAAGAGCA TATTATGGAA TGTTCTGAAA CAGAAAGCTG AATCCCTTCA GATTTCCCTT 1440

GAATGTGGTA CTCTAAAGAA TTCTGTTGCT GAGGCATTAG AAGGAATCAC TATTGTATTA 1500

CAGCTGACTG CTCTCTGCAC TGTTCACTGT TCTCATCAAG ACATGGATGG CCATAATGCC 1560

AAGGATTGTC AACACAAATA TAAGAAGAAA CCTCCAGTAG TAATAACTTG GATGTCTTTG 1620

GATTTTTATA CAAAAGTGCT TAAAAGCTGT AAGAGTTTGT TAGAATCTGT TCAGAAACAT 1680

GAACTGGAAT TAGTCATCGA TAGTGTGGTG AGAATTTATG ATGCTTTGAT GTATATACAA 1740

GTAAAAAGTT CATTTCAAGA TCATGTTCTG GAAGAGTTAT GTGGAATGCT CTCACTTCCT 1800

TGGATTTATT CCTATTCTGA TGATAACTCT TTAAAGATGA CCACATTTGC TACTAACCTT 1860

CTGCGGTTAA GCCAGAGGGT TTGGGAAAGT TACTCTCCAC AGGCACAGTC ACAATGCGTG 1920

TTTCTTCTGA CACTGTTTCC AAAAAGAATA TTCCTTGACT GGAGAACAAC AGTTTATAAT 1980

TGGGCCTTGA AGAGCTCCCA TGAAGTAATC CGGACTAGTT GTGTTAAAGG ATTTTTTATC 2040

TTATTGCAGC AGGAGAATTC TTGTAATCAA ATTCCCAAGA TGCTAATAGA TAGAGTCAAA 2100

GATGATTCTC ACGTGGTCAA GAAAGAATTT GCTTCTGTCC TTGGTCAACT TGTCTGTACT 2160

CTTCATGGCA TGTTTTATTT GACAAGTTCC TCGGTAGAGC CTTTCTTTGG ACCTGTGGAC 2220

TTGTTCTGTA AGAACCTGAA AGCCACTTCT CAACATGAAT GTTCATCTTC TCAAGTAAAA 2280

GCTTCCGTTT GCAAGCCATT CCTTTTCCTG CTGACTAAAA ATACACCTAG TCCAGTAAAA 2340

CTTGCTTTCA TAGACAATCT GCATCATCTT TGTAAGCATC TTGATTTTCA AGAAGATGAA 2400

ACAGAGGTAA AAGCAGTTCT TGGCACTTTA TTAAATTTGA TGGAAGATCC AGACAAGGAT 2460

GTTAGAATAG CTTTTAGTGG AAATATCAAG TATATATTGG AATCTTTGAA CTCTGAAGAT 2520

GGATTCATAA AAGAGCTTTT TGTGTTAAGA ATGAAGGAAG CATATACACA TGCCCAGATA 2580

TCAAGGAGTA ATGAGCTGAA GGACACCTTG ATTCTTACAA CAGGGGATAT TGGAAGGGCA 2640

GCAAAAGGAG ATTTGATACC TTTTGCACTC TTGCATTTAC TGCATTGCTT GTTGTCTAAG 2700

TCTGCATCCG TCTCTGGAGC GGCATACACA GAGATCCGAG CACTAGTTGC AGCCAAAAGT 2760

GTTAAACTAC AGAATTTTTT CAGTCAATAT AAGAAACCAA TCTGTCAGTT TTTGGTAGAA 2820

TCTCTCCACT CCAGTCAGAT GACAGCACTC CCAAGTACTC CTTGCCAGAC TGCTGAGATG 2880

CGAAAACAAC ATGTTGCTCA TCACAGAGAA ATGGCTTTAA ATACCTTATC AGAAATTGCC 2940

AATGTTTTTG ACTTTCCTGA TCTTAATCGT TTCCTGACAA GGACATTACA AGTTCTACTT 3000

CCTGATCTGG CCGCCAAAGC AAGTCCTGCA GCATCGGCTC TCATCCGAAC TTTAGGGAAA 3060

CAATTAAATG TCAACCGTCG AGAGATTTTA ATAAATAACT TCAAATATAT TTTTTCTCAT 3120

TTGGTTTGTT CTTGTTCCAA AGATGAATTA GAACGTGCCC TTCATTATCT GAAGAATGAA 3180

ACAGAAATTG AGTTGGGGAG CCTGTTAAGA CAGGATTTTC AAGGATTGCA CAATGAATTA 3240

TTGCTGCGTA TTGGAGAACA TTATCAACAA GTTTTCAATG GTTTGTCAAT CCTTGCCTCA 3300

TTTGCATCTA GTGATGATCC GTATCAAGGA CCACGAGATA TCACATCGCC TGAACTGATG 3360

GCTGATTATT TGCAACCGAA ATTGTTGGGC ATTCTAGCCT TTTTTAATAT GCAGTTACTG 3420

AGCTCCAGTG TTGGTATTGA AGATAAAAAA ATGGCCTTGA CTAGTTTGAT GTCTTTGATG 3480

AAGTTGATGG GACCTAAGCA TGTTAGTTCT GTGAGAGTAA AGATGATGAC CACACTGAGA 3540

ACTGGACTGA GATTCAAGGA TGATTTCCCT GAGTTATGCT GCAGAGCATG GGACTGCTTT 3600

GTTCGTTGTC TGGACCACGC TTACCTGGGA CCCCTGCTCA GTCATGTCAT AGTGGCTTTG 3660

CTACCTCTCA TACAGATGCA GCCTAAAGAA ACTGCGGCTA TCTTTCACTA CCTCATCATT 3720

GAAAACAGGG TTGCCGTGCA AGATTTTCTT CATGAAATAT ATTTTCTGCC TGATCATCCA 3780

GAATTAGAAA AGATAAAAGC AGTTCTGCAG GAATATAGAA AGGAAACCTC TGAGAGTACT 3840

GATCTTCAAA CCACTCTCCA GCTCTCTATG AAAGCAATTC AGCATGAAAA TGTAGATGTT 3900

CGTATTCATG CTCTTACCAG CTTGAAGGAA ACCTTGTACA AAAACCAGGA AAAACTGATA 3960

AAATATGCAA CTGATAGTGA AACAGTGGAG CCTGTTATCT CCCAGCTTGT GACAGTAATT 4020

TTGAAAGGCT GCCAAGATGC AAACTCTCAA GCTCGCTTGC TCTGTGGGGA ATGTTTAGGA 4080

GAACTGGGAG CAATAGACCC AGGACGATTA GATTTCTCAA CAACAGAAAC TCAGGGAAAA 4140

GATTTTACAT TTGTGACTGG AGTAGAAGAT TTAAGCTTTG CCTATGGATT GCTGATGGAG 4200

CTAACAAGAG CTTACCTTGC GTATGCCGAT AACAGCCGAG CACAAGATTC AGCTGCTTAT 4260

GCCATTCAGG AGTTACTTTC TATTTATGAC TGTAGAGAGA TGCAGAGCAA TGGCCCAGGC 4320

CACCAGTTGT GGAAGAGATT CCCTGAGCAC GTCCGAGAAA TATTAGAACC TCATCTTAAT 4380

ACTAGATATA AGAGTTCCCA GAAGTCAACA GATTGGTCTG GAGTAACGAA GCCAATTTAC 4440

TTAAGTAAAC TAGGTAATAA CTTTGCAGAA TGGTCATCAT CTTGGGCAGG TTATCTTATA 4500

ACAAAGGTCC GGGATAATCT TGCCAGTAAA ATCTTCACCT GCTGTAGTAT AATGATGAAG 4560

CATGATTTCA AAGTCACCAT CTATCTCCTT CCACATATCC TAGTATATGT CTTGTTGGGT 4620

TGTAGTCAAG AAGATCAGCA AGAGGTTTAT GCAGAAATTA TGGCAGTACT TAAGCATGAT 4680

GATCAGCATG CCATCAGTAC CCAGGACAGT GCATCGGATC TGTGCCAGTT GAGTACACAG 4740

ACTGTGTTCT CTATGCTTGA CCATCTCACC CAATGGGCAA GGCACAAATT TCAGGCATTG 4800

AATGCTGAGA AACTTGCACA AAACAAACCA AAAGGAGGTA AGGTCAACTA TCCAGTATCA 4860

AGTGTGAATT TTGAAGACTA TCAGAGTGTA ACTCGTTTTC TAGACCTCAT ACCTCAGGAT 4920

ACTCTGGCTG TAGCCTCCTT TCGTTCCAAA GCATACACAC GAGCCGTAAT GCACTTTGAG 4980

TCATTTATTA CAGAAAAGAA GCAAAATATT CAAAAGCATC TTGGATTTCT ACAGAAATTG 5040

TATGCTGCTA TGCATGAACC AGATGGAGTG GCTGGAGTAA GTGCAATTCG AAAAGCAGAG 5100

CCATCACTGA AGGAACAGAT TCTTGAGCAT GAAAGTATTG GCTTGCTGAG GGATGCCACT 5160

GCCTGTTATG ACAGGGCTAT TCAGCTAGAA CCGGACCAGA TCATTCATTA TCATGGTGTC 5220

GTGAAGTCCA TGTTAGGTCT TGGTCAGCTG TCCACTGTAA TCACCCAGGT CAATGGAGTG 5280

CATGCTAATA GGTCTGAATG GACAGATGAA TTAAACACAT ACAGAGTTGA AGCAGCTTGG 5340

AAACTGTCAC AGTGGGATTT GGTGGAAAAC TACTTGGCAG CAGATGGGAA ATCCACAACG 5400

TGGAGTGTCA GACTAGGACA GCTACTGTTA TCAGCTAAAA AGAGGGACAC CACAGCTTTC 5460

TATGACACAC TGAAACTAGT GAGAGCAGAA CAAATTGTAC CTCTCTCAGC TGCAAGCTTC 5520

GAAAGAGGCT CCTACCAACG AGGATATGAA TTTATTGTCA GGTTACACAT GTTGTGTGAG 5580

TTGGAGCACA GCCTCAAACC ACTTTTTCAC AAGTTTCCAG GTGACAGTTG TAATGAAGAC 5640

TCTCTGAACT GGGCAGCTCG ACTAGAAATG ACCCAGAATT CCTACAGAGC AAAGGAGCCT 5700

ATCCTGGCCC TCCGGAGGGC TTTATTAAGT CTCAACAAAA GGCCTGATTA CAATGAAATG 5760

GTTGGAGAAT GCTGGCTACA GAGTGCCAGG GTAGCTAGAA AGGCTGGGCA CCATCAGACA 5820

GCCTACAATG CTCTCCTTAA TGCTGGAGAG TCACGACTTG CCGAACTCTA TGTGGAAAGG 5880

GCGAAGTGGC TGTGGTCCAA GGGTGATGTT CACCAGGCGC TTATTGTTCT TCAAAAGGGG 5940

GTTGAATTAT GTTTTCCTGA AAATAAATCC CCAACTGAGA GTAAGCACAT GTTAATCCAT 6000

GGTCGAGCTA CACTGCTCGT TGGCCGGTTT ATGGAAGAAA CAGCTAACTT TGAAAGCAAC 6060

GCAATTATGA AGAAATATAA GGATGTGACC TTGTTTCTGC CAGAGTGGGA AGATGGGCAT 6120

TTCTACCTTG CCAAGTACTA TGACAAGTTG ATGCCCATGG TAACAGATAA CAAAATGGAA 6180

AAGCAAGGCG ATCTCATCCG ATATATAGTC CTACATTTTG GAAGATCTCT TCAGTATGGA 6240

AATCAGTTCA TATATCAATC AATGCCACGA ATGTTATCGC TATGGCTTGA TTTTGGTGCT 6300

AAGGCATACG AATGGGAAAA AGGTGGTCGT TCTGATCGTC TGCAAATGAG AAATGATTTG 6360

GCAAAAATAA ATAGTGTACT CACAGAGCAC ACAAATCGGT TAGCACCATA TCAGTTTTTG 6420

ACTGCTTTTT CGCAGTTGAT CTCTCGAATT TGTCATTCTC ATGATGAAGT TTTTGTTGTC 6480

TTGATGGAAA TAATAGCCAA GGTCTTTCTG GCCTATCCTC AGCAAGCAAT GTGGATGATG 6540

ACTGCTGTGT CAAAGTCTTC TTATCCCATG CGTGTGAACA GATGCAAGGA AATTCTTACC 6600

AAAGCTATCC ATATGAAAAA GTCTTTAGAA AAGTTTGTCG GAGATGCAAC TCGCCTAACA 6660

GACAAGCTAC TAGAGTTATG CAACAAATCG GTTGATGGAA GTAATTCTAC ATTGAGCATG 6720

AGCACTCACT TTAAAATGCT TAAAAAGCTG GTAGAAGACC CAACATTTAG TGAAATCCTC 6780

ATTCCTTTGC AGTCAGTCAT GATACCTACT CTTCCATCAA TTCTGGGTGC CCATGCTAAT 6840

CATGACCCCT TTCCTGGGCA TTGGGCCTAT CTTGCAGGCT TCGACGATGT GGTAGAAATT 6900

CTTTCTTCTC TTCAGAAACC AAAGAAAATC TCCTTAAAGG GCTCAGATGG AAAATTCTAT 6960

ATCATGATGT GTAAACCAAA AGATGATTTG AGAAAAGACT GTAGACTAAT GGAATTTAAT 7020

TCTTTGATTA ACAAGAGCTT AAGAAAAGAT GCAGAATCAC GTCGAAGAGA ACTTCATATC 7080

CGAACATATG CAGTTATTCC ACTGAATGAT GAGTGTGGGA TTATTGAATG GGTGAACAAC 7140

ACTGCTGGCT TGAGACCTAT TCTGACCAAA CTATACAAAG AAAAGGGAGT GTATATGACA 7200

GGAAAGGAAC TTCGCCAGTG TATGCTACCA AAGTCAGCAG CTTTATCTGA AAAACTCAAA 7260

GTATTCCAAG AAATACTCCT GCCCAGGCAC CCTCCTGTTT TTCATGAGTG GTTTCTAAGA 7320

ACATTCCCTG ATCCTACATC ATGGTACAGC AGTAGGTCCG CATACTGCCG TTCTACTGCG 7380

GTCATGTCAA TGGTTGGCTA TATCCTGGGG CTTGGAGACC GTCATGGTGA AAACATTCTT 7440

TTTGATTCTT TCACTGGTGA ATGTGTACAT GTAGACTTCA ACTGTCTTTT TAATAAGGGA 7500

GAAACTTTTG AAGTTCCAGA AATTGTACCA TTTCGACTGA CTCATAATAT GGTTAATGGA 7560

ATGGGTCCTA TGGGAACAGA GGGTCTGTTT CGAAGAGCAT GTGAAGTTAC ACTGAGACTG 7620

ATGAGGGATC AGCGCGAACC TTTAATGAGT GTCTTAAAGA CTTTTCTGCA TGATCCTCTC 7680

GTGGAATGGA GTAAACCAGT GAAAGGACAC TCCAAAGCAC CACCGAATGA AACCGGGGAA 7740

GTTGTCAATG AGAAGGCTAA GACCCATGTT CTTGACATTG AACAACGACT ACAAGGTGTA 7800

ATCAAGACCC GGAATAGAGT AACAGGGCTG CCGTTATCTA TTGAAGGACA TGTGCATTAT 7860

CTCATACAAG AAGCTACTGA TGAAAACTTA CTATGTCAGA TGTACCTTGG TTGGACCCCA 7920

TATATGTAA 7929

Domain Profile

S: 2     agfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdk  61

         agfd+ veil+s+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N+ L+kd+

Q: 2292  AGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDA  2351

         89**********************************************************

S: 62    etsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdls  121

         e++rr+L+irty+V+pl++++g+iewv+nt++L+ +l+kl+++k+v++        + ++

Q: 2352  ESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYM--------TGKE  2403

         ************************************************........599*

S: 122   tvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAvi  181

          +q++ pk+++l+++l+vf+e+l +++p+ ++++++l++fp+p++w+++r+ay+rs+Av+

Q: 2404  LRQCMLPKSAALSEKLKVFQEILLPRHPP-VFHEWFLRTFPDPTSWYSSRSAYCRSTAVM  2462

         ****************************8.******************************

S: 182   slvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivnal  241

         s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn++

Q: 2463  SMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNGM  2521

         ****************************************.*******************

S: 242   gvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketeee  296

         g++g+eG+fr++ce +lr++r+++e l+++L++fl+dplv+w+k     +k++ +et+e+

Q: 2522  GPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKpvkghSKAPPNETGEV  2581

         ************************************************99**********

S: 297   laekakaealkikkllskvekaenavatrdllllee  332

         ++ekak++ l+i+++l++v k++n+v+ ++l+++++

Q: 2582  VNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGH  2617

         *******************************99987

Domain Sequence
(FASTA)

AGFDDVVEIL SSLQKPKKIS LKGSDGKFYI MMCKPKDDLR KDCRLMEFNS LINKSLRKDA 60

ESRRRELHIR TYAVIPLNDE CGIIEWVNNT AGLRPILTKL YKEKGVYMTG KELRQCMLPK 120

SAALSEKLKV FQEILLPRHP PVFHEWFLRT FPDPTSWYSS RSAYCRSTAV MSMVGYILGL 180

GDRHGENILF DSFTGECVHV DFNCLFNKGE TFEVPEIVPF RLTHNMVNGM GPMGTEGLFR 240

RACEVTLRLM RDQREPLMSV LKTFLHDPLV EWSKPVKGHS KAPPNETGEV VNEKAKTHVL 300

DIEQRLQGVI KTRNRVTGLP LSIEGH 326

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0001741	; C:XY body
GO:0004674	; F:protein serine/threonine kinase activity
GO:0071480	; P:cellular response to gamma radiation
GO:0034644	; P:cellular response to UV
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0008156	; P:negative regulation of DNA replication
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043517	; P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777	; P:protein autophosphorylation
GO:0043393	; P:regulation of protein binding
GO:0090399	; P:replicative senescence

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013