| Tag | Content |
|---|
| EKPD ID | EPS-RAN-00003 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 192.0 | 5.7E-57 | 62 | 205 | 144 |
|
| Status | Reviewed |
| Ensembl Protein | ENSRNOP00000015725 |
| UniProt Accession | Q5FVI9; |
| Protein Name | Dual specificity protein phosphatase 26 |
| Protein Synonyms/Alias | |
| Gene Name | Dusp26 |
| Gene Synonyms/Alias | Dusp26; |
| Ensembl Information | |
| Organism | Rattus norvegicus |
| Functional Description | Inactivates MAPK1 and MAPK3 which leads todephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity (By similarity). |
| Protein Length | 211 |
Protein Sequence
(FASTA) | | MCPGNWLWAS MTFMARFSRS SSRSPVRTRG SLEEMPSVHH PFLNVFELER LLYTGKTACN 60 | | HADEVWPGLY LGDQDMANNR RELRRLGITH VLNASHSRWR GTPEAYEGLG IRYLGVEAHD 120 | | SPAFDMSVHF QTAADFIHRA LSQPGGKILV HCAVGVSRSA TLVLAYLMLY HHFTLVEAIK 180 | | KVKDHRGIIP NRGFLRQLLA LDRRLRQGLE A 211 |
|
Nucleotide Sequence
(FASTA) | | ATGTGCCCCG GTAACTGGCT GTGGGCTTCC ATGACTTTTA TGGCCCGCTT CTCCCGAAGC 60 | | AGCTCAAGGT CCCCTGTTCG TACCCGAGGG AGCCTGGAGG AGATGCCCAG TGTTCACCAT 120 | | CCCTTCCTCA ATGTCTTTGA GTTGGAAAGG CTCCTCTACA CGGGCAAGAC AGCCTGCAAC 180 | | CATGCTGACG AGGTCTGGCC AGGCCTCTAC CTCGGAGACC AGGACATGGC CAACAACCGC 240 | | CGTGAGCTTC GTCGCCTGGG CATCACCCAC GTCCTCAACG CCTCCCACAG CAGGTGGCGA 300 | | GGCACCCCCG AGGCCTACGA GGGACTGGGC ATCCGCTACC TGGGTGTTGA AGCCCACGAC 360 | | TCGCCAGCCT TTGACATGAG CGTCCACTTT CAAACCGCTG CGGACTTTAT CCATCGGGCA 420 | | CTGAGCCAGC CAGGAGGGAA GATCCTGGTG CACTGTGCGG TGGGAGTGAG CAGATCTGCC 480 | | ACCCTGGTGC TGGCCTACCT CATGCTGTAC CACCACTTCA CCCTCGTGGA GGCCATCAAG 540 | | AAAGTCAAGG ACCACCGAGG CATCATCCCC AACAGGGGCT TCTTGAGACA GCTCCTAGCC 600 | | CTGGACCGTA GGCTGCGTCA GGGTCTAGAA GCATGA 636 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +e++pglylgdq++a++rreL++lgit+v+nas+s+++ ++Pe+++ gi+y++++++ | Q: 62 ADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWR--GTPEAYEGLGIRYLGVEAH 119 | 799************************************..******************* |
| S: 62 Dsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi 120 | Ds+++d++ +f++aa+fi++a +++ggk+lvHCa+GvsRSatlvlaYLm +++++l++Ai | Q: 120 DSPAFDMSVHFQTAADFIHRAlSQPGGKILVHCAVGVSRSATLVLAYLMLYHHFTLVEAI 179 | *********************9999*********************************** |
| S: 121 eavkrkrpsiepnegfleQLlelekkl 147 | ++vk++r i+pn+gfl+QLl+l+++l | Q: 180 KKVKDHR-GIIPNRGFLRQLLALDRRL 205 | *******.9***************997 |
|
Domain Sequence
(FASTA) | | ADEVWPGLYL GDQDMANNRR ELRRLGITHV LNASHSRWRG TPEAYEGLGI RYLGVEAHDS 60 | | PAFDMSVHFQ TAADFIHRAL SQPGGKILVH CAVGVSRSAT LVLAYLMLYH HFTLVEAIKK 120 | | VKDHRGIIPN RGFLRQLLAL DRRL 144 |
|
| Keyword | Complete proteome; Cytoplasm; Golgi apparatus; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |