EPS-RAN-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-RAN-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	210.0	6.3E-62	60	317	258

Status

Unreviewed

Ensembl Protein

ENSRNOP00000022227

UniProt Accession

D3ZP99;

Protein Name

Protein Synonyms/Alias

Protein RGD1562091;

Gene Name

Ppm1n

Gene Synonyms/Alias

Ppm1n; RGD1562091;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSRNOG00000016599	ENSRNOP00000022227	ENSRNOT00000022227

Organism

Rattus norvegicus

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MAAFAHLLKR LGWAARAQEV TEQELEEECS VPGAPWRLLV APRCWQRLHG GAAAASGLRF 60

GASAVQGWRA RMEDAHCAQL ALPGLPSGWA FFAVLDGHGG ARAARFGARH LPGHVLGELG 120

PAPREPDGVR QALRSAFLHA DSQLSKLWPR CDPGGSTAVA LLVSPRFLYL AHCGDSRALL 180

SRSGSVAFCT EDHRPHRPRE RERIHDAGGT VRRRRVEGSL AVSRALGDFA YKQAPGRPPE 240

LQLVSAEPEV AALARQDEDE FVLLASDGVW DALSGADLAG LVTSRLRLGL DPELLCAQLL 300

DTCLCKGSLD NMTCMVVCFP GAPRPCEEAI SKEMALDAVL SHKVAELYAS AQEPPCLNTV 360

FRTLASE 367

Nucleotide Sequence
(FASTA)

ATGGCGGCCT TTGCACACTT GTTGAAGCGA CTCGGATGGG CCGCTCGAGC TCAGGAGGTG 60

ACGGAGCAAG AGCTGGAGGA GGAGTGCAGC GTCCCGGGCG CTCCTTGGAG ACTCCTGGTA 120

GCGCCCCGGT GCTGGCAGAG GTTACACGGG GGTGCGGCGG CCGCATCTGG TCTGCGCTTC 180

GGAGCAAGCG CCGTGCAGGG CTGGCGCGCG CGTATGGAGG ACGCGCACTG TGCTCAGTTG 240

GCTTTGCCTG GGCTGCCATC AGGATGGGCT TTTTTCGCGG TCCTGGATGG CCATGGAGGA 300

GCGCGGGCCG CGCGCTTCGG AGCGCGCCAC CTCCCGGGTC ACGTGCTGGG GGAACTGGGT 360

CCCGCGCCCC GAGAGCCCGA TGGTGTGCGC CAGGCTCTTC GTAGCGCCTT CCTCCACGCA 420

GACTCTCAGC TGAGCAAGCT CTGGCCCCGC TGCGACCCCG GTGGCTCGAC GGCTGTGGCT 480

CTGCTCGTGT CCCCGCGATT CCTCTACCTG GCGCACTGCG GGGACTCGCG CGCGCTGCTG 540

AGCCGCTCAG GCTCGGTGGC CTTCTGCACC GAGGACCACC GTCCCCACCG GCCTCGGGAA 600

CGCGAGCGCA TCCACGACGC CGGTGGCACA GTCCGTCGCC GGCGCGTAGA GGGCTCCCTG 660

GCCGTGTCGC GAGCCCTAGG TGACTTCGCC TACAAGCAGG CACCGGGGAG GCCTCCTGAG 720

CTGCAGCTCG TGTCCGCTGA GCCCGAGGTG GCTGCGCTGG CACGCCAGGA CGAGGATGAG 780

TTCGTGCTCT TGGCTTCCGA TGGCGTTTGG GACGCTCTGT CTGGTGCGGA CCTGGCGGGG 840

CTGGTGACGT CGCGCCTTCG TCTGGGCCTG GACCCGGAAC TACTCTGTGC GCAGCTGTTG 900

GACACGTGTC TGTGCAAGGG AAGTCTGGAT AACATGACCT GCATGGTGGT CTGCTTCCCT 960

GGGGCCCCCA GGCCTTGTGA GGAGGCAATC AGCAAGGAGA TGGCTTTAGA CGCAGTCCTG 1020

AGCCACAAAG TCGCTGAGCT GTATGCCTCT GCTCAGGAAC CTCCATGCCT AAACACGGTT 1080

TTCAGGACCC TGGCCTCAGA G 1101

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++v+g+r  meda+ ++  +   p+  + +aff+v DGhgg ++a+f + +l  ++

Q: 60    FGASAVQGWRARMEDAHCAQLAL---PGLPSGWAFFAVLDGHGGARAARFGARHLPGHVL  116

         7899*************764443...444445****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

          el    +e + v++al++aFl+ d++l   ++   ++d+ Gstav  l+++  ly a++

Q: 117   GELGPAPREPDGVRQALRSAFLHADSQL---SKLWPRCDPGGSTAVALLVSPRFLYLAHC  173

         ****99999*******************...666667***********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSra+L+r+g++   ++dH+p r++E+eRi +agg+v ++   Rv G+LavsRalGd+

Q: 174   GDSRALLSRSGSVAFCTEDHRPHRPRERERIHDAGGTVRRR---RVEGSLAVSRALGDFA  230

         ****************************************9...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v++ePev    ++ edef+ LasDG+wd +s  ++  lv+++l+ +

Q: 231   YKqapgrppelQLVSAEPEVAALARQDEDEFVLLASDGVWDALSGADLAGLVTSRLRLGL  290

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         +++  + +L++++l +gs dn++ +vv

Q: 291   DPELLCAQLLDTCLCKGSLDNMTCMVV  317

         ***********************9997

Domain Sequence
(FASTA)

FGASAVQGWR ARMEDAHCAQ LALPGLPSGW AFFAVLDGHG GARAARFGAR HLPGHVLGEL 60

GPAPREPDGV RQALRSAFLH ADSQLSKLWP RCDPGGSTAV ALLVSPRFLY LAHCGDSRAL 120

LSRSGSVAFC TEDHRPHRPR ERERIHDAGG TVRRRRVEGS LAVSRALGDF AYKQAPGRPP 180

ELQLVSAEPE VAALARQDED EFVLLASDGV WDALSGADLA GLVTSRLRLG LDPELLCAQL 240

LDTCLCKGSL DNMTCMVV 258

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013